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Pediatrics in Practice: Positive Antinuclear Antibody: What Now?

“Positive ANA” is one of the most common reasons for referral to the pediatric rheumatology clinic. The antinuclear antibody (ANA) is often mistakenly considered a good screening test for rheumatic disease. Dr. Ashley Cooper, Interim Division Director of Pediatric Rheumatology, discusses what it means when a child has a positive anti-nuclear antibody test, when ANA should be checked, and how to talk about the test results with the family.


Common Orthopedic Conditions and How to Treat Them

Orthopedic conditions can cause pain and dysfunction, causing aches and pains in bones and joints. Mobility and activity may be limited by these conditions. Polly Wimer, CPNP, APRN discusses common orthopedic conditions and their treatment.


Pediatrics in Practice: The Opioid-Pain Nexus: Current Opioid Use and Safety

Although there has been less emphasis on responsible prescribing of opioids in children, with newly developed legal and regulatory efforts focused almost exclusively on adults, it remains important for pediatric providers to be aware of the heightened risk for substance misuse in adolescents, and the appropriate use of opioids in a pediatric population. In this podcast, Daniel Millspaugh, MD, anesthesiologist and Director of the Comprehensive Pain Management and Opioid Stewardship...


Pediatrics in Practice: Primary Care for Pediatric Cancer Survivors

As pediatric cancer survival rates continue to improve, we are faced with a new set of health challenges in caring for these survivors. Joy Fulbright, MD, Director of the Survive and Thrive program at Children’s Mercy Kansas City, discusses health concerns after cancer treatment, what primary care providers need to know, and the need for yearly screenings addressing medical and psychosocial issue.


Previously Untreated Patients with Hemophilia Matter

As regional hemophilia treatment center, Children's Mercy follows more than 900 patients with bleeding disorders. Listen as Shannon Carpenter, MD, pediatric hematologist/oncologist and director of the Hemophilia Treatment Center at Children's Mercy Kansas City, discusses hemophilia A and B in children, current treatments and promising new research studies and options on the horizon, such as the PUPS Matter cohort study.


Getting in Front of Type 2 Diabetes

Type 2 diabetes was commonly associated with the adult population. This diagnosis was even referenced as adult-onset diabetes but in recent years type 2 diabetes in children is on the rise. Although researchers aren’t clear as to why some children develop type 2 diabetes there are some causes that can increase the risk. When children present with these risks the Children Mercy Diabetes Center can evaluate these patients and create a care plan to possibly alter the path to such a...


Kids and Kidney Stones

Kidney stones in children have been on the rise for more than a decade, mostly due to hypercalciuria and hypocitraturia. Join us as Uri Alon, MD, Director of the Bone and Mineral Disorders Clinic at Children’s Mercy Kansas City, discusses what is behind the increasing incidence of kidney stones, and medical and non-pharmacological interventions to prevent new stones and inhibit the growth of existing ones.


Is There a Role for Fecal Transplant in IBD?

Can an effective treatment for medically refractive Crohn’s disease be found in the gastrointestinal tract itself? Dr. Alka Goyal with Children’s Mercy Kansas City is exploring the role of fecal transplant as a rescue therapy for patients whose inflammatory bowel disease has not responded to traditional treatment. Early research showed that a single transplant is relatively safe and can result in a short-term response in young patients with active IBD but doesn’t provide long-term relief....


Tourette Syndrome: Using an Evidence-based Algorithm to Guide Treatment

As an expert in the treatment of Tourette Syndrome (TS), recently, Dr. Coffman was asked to author an article on the pharmacological treatment of Tourette Syndrome. In collaboration with Dr. Quezada, the paper was published in CNS Drugs Journal, focusing on current approaches and new developments regarding treatment of Tourette Syndrome. The team developed a visual algorithm to help guide the treatment of TS using medication based on the level-of-evidence and side-effects. It has been...


Cancer Genomics: Finding Answers Through Data and DNA

Approximately 10 to 15 percent of childhood cancer cases are due to a genetic predisposition. Children’s Mercy Kansas City is searching within the genetic code to not only identify genes that may lead to cancer, but to find answers in how to better treat or cure pediatric cancer. Erin Guest, MD, Director of Cancer Genomics at Children’s Mercy, discusses the growing role of cancer genomics and how big data, new tests, and personalized treatments could change the future of pediatric cancer...


The Decision to Withhold Life-Sustaining Medical Treatment for Children

In pediatrics care most often supports life-sustaining treatment to promote the best interests of the child. But in some circumstances (after weighing the balance of benefits and burdens of a range of treatment choices) continuing life-sustaining treatment is decided to no longer be in the child’s best interests. Collaboration and clear communication are essential in these difficult discussions. Join Bioethicist and Neonatologist Brian Carter, MD at Children’s Mercy Kansas City, as he...


The Importance of Reducing Pediatric Lawnmower-Related Injuries

Did you know over 17,000 children are treated for lawnmower injuries each year in the US, resulting in 4,000 trips to the ER. About 75 children die annually from these injuries. Our Guest Dale Jarka, MD is leading a first of its kind research study at Children’s Mercy to better define the causes, patterns and effects of Lawn Mower injuries, identify predictors of severe injuries in order to elevate public education and prevent injuries.


Lessons Learned from the CKID Study

What are the risk factors for CKID progression? Should children with CKID be screened for cardiovascular risks? Can we predict relative time to a composite event? These are a few of the questions being answered by the CKID study. To date, the translational research study has resulted in more than 90 publications. Listen as Dr. Warady highlights some of the key findings that are shaping care and providing answers that matter now to pediatric patients with CKID.


Fetal Surgery Interventions: Hope, Hype and the Future

Since opening as one of the first fetal centers based in a children’s hospital, the Elizabeth J. Ferrell Fetal Health Center at Children’s Mercy has delivered nearly 1,000 high-risk babies, with more than one third having complex heart disease. The addition of Emmanuel “Mike” Vlastos, MD, further expands the center’s fetoscopy experience, which includes open myelomeningocele repair and other advanced in-utero procedures. While fetal surgery has been around for decades, the hope has not...


Pediatrics in Practice: Bacterial Infection in Neonates and Young Infants

Infants under 90 days old with fever can present a diagnostic dilemma. Join us as Russell McCulloh, MD discusses unresolved issues and common conundrums faced by front-line clinicians in the evaluation of neonatal fever, recent literature on laboratory testing for infants with fever, and potential management strategies for febrile infants.


Innovative Interventions for Children with Type 1 Diabetes

How can technology improve adherence and control for children and their families dealing with type 1 diabetes? Mark Clements, MD, PhD, Endocrinologist and Associate Professor of Pediatrics, University of Missouri-Kansas City School of Medicine, and Susana Patton, PhD, Psychologist and Professor of Pediatrics, University of Kansas Medical School, are working in partnership on three unique collaborative projects funded by the National Institutes of Health which are utilizing technology to...


Help for Opiate Exposed Babies: Family-Centered NAS Care Initiative

The recent trend in infants born exposed to neurotropic substances during pregnancy is increasing at an alarming rate across the United States, posing a public health threat in the form of neonatal abstinence syndrome (NAS). Jodi Jackson, MD, Children’s Mercy Neonatologist and Medical Director of the Shawnee Mission Medical Center (SMMC) level III NICU, has implemented family-centered care initiatives that have improved outcomes for these infants. This family-centered protocol for NAS has...


Cancer Immunotherapy and the Promise of CART19

Acute lymphoblastic lymphoma is the most common childhood cancer, with about 3,100 patients younger than 20 diagnosed every year, according to the National Cancer Institute. Children’s Mercy contributed to the trial of the first U.S. approved cancer gene therapy, Kymriah, for children and young adults with acute lymphoblastic leukemia that is resistant to treatment or has relapsed. Doug Myers, MD, Children’s Mercy oncologist, was an early investigator of immunotherapy using chimeric...


What is a Voiding Dysfunction?

Voiding dysfunctions comes in all shapes, sizes and symptoms. With so many presentations, sometimes the common feels uncommon, but you are not alone! Mary Langston, RN, MSN, CPN, PPCNP-BC discusses voiding dysfunctions and what strategies primary care providers and families can use to help a child before referral to a specialist.


Multidisciplinary Sickle Cell Pulmonology Clinic

In patients with sickle cell concurrent pulmonary issues such as asthma, allergies, sleep apnea and acute chest syndrome are common. Alvin Singh, MD, is helping save these sickle cell patients an extra trip to the hospital through the multidisciplinary sickle cell pulmonary clinic. Dr. Singh ensures that patients are well oxygenated, ventilated and that pulmonary issues don’t affect their sickle cell disease. Listen in as Alvin Singh, MD explains that although acute chest syndrome is the...