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Explore the world of neuroscience and the secrets of the brain. Discover how the brain works, technologies to harness brain power, ways to treat disease, and more.

Explore the world of neuroscience and the secrets of the brain. Discover how the brain works, technologies to harness brain power, ways to treat disease, and more.
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Explore the world of neuroscience and the secrets of the brain. Discover how the brain works, technologies to harness brain power, ways to treat disease, and more.




Melding Minds with Machines: Development of Implantable Interfaces to Restore Motor Function

Millions of Americans have difficulties with their physical functioning. Dr. Karunesh Ganguly explores the Brain-Computer Interface (BCI). The concept of bio-interactive neural interfaces sates to the early 20th century with successes like cochlear implants, deep brain stimulation and responsive stimulation. He is now working on neural interfaces for communication and movement by working to translate neural engineering based approaches into treatments for those with impaired function....


Staying Sharp: Current and Future Approaches to Brain Health and Alzheimer’s Therapeutics

Dr. Aimee Kao looks at recent news in Alzheimer's Disease therapeutics including drugs in development and the potential of stem cells and genome editing. Series: "Mini Medical School for the Public" [Show ID: 35238]


Sensory Implications of Brain Organoids with Patricia Churchland

What defines consciousness? Can it develop in a petri dish? Patricia Churchland reviews the current state of brain organoid research and shares her views on how conciseness and physical structures within the brain intersect. She also cautions the media on the tendency to "over hype" new research advances. Series: "Stem Cell Channel" [Show ID: 35247]


Neural Organoids Are Not Brains in Vats with Evan Thompson

Recently, some scientists have asked whether neural organoids will ever be conscious, and have wondered about the ethical implications of this possibility. Meanwhile, some philosophers have argued that neural organoids are miniature versions of “brains in vats.” Evan Thompson feels that both scientist and philosophers should shift their thinking. He argues that the minimal instantiation of sentience is organismic - not just neuronal, and that conscious processes of moral interest require...


Consciousness in Cerebral Organoids - How Would We Know? with Christof Koch

As brain organoids become more widely used in research, concerns about the development of consciousness arise. Christof Koch discusses how we determine and define consciousness and how we look for the underlying physical signatures of consciousness. Series: "Stem Cell Channel" [Show ID: 35246]


The Current Status of Human Brain Organoids Research with Alysson Muotri and Larry Goldstein

The study of brain organoids is leading to a better understanding of human development and potential therapies for neurological disorders. Yet when people hear the phrase "brain in a dish" it instantly brings to mind the stuff of science fiction - labs full of sentient brains thinking and plotting. Alysson Muotri explains why these organoids should not called "brains in a dish" and how they are being used to explain human processes previously inaccessible to study. While underscoring...


APOE TREM and Microglia in the Pathogenesis of Tau-mediated Neurodegeneration with David Holtzman MD - Shiley Endowed Lecture

David M. Holtzman, MD of the Washington University School of Medicine discusses the mechanisms underlying neurodegeneration and how microglia and specific microglial genes such as TREM2 influence neurodegeneration in the setting of Aβ and tau pathology. Learn how this line of study may lead to new therapeutics and diagnostic testing for Alzheimer's disease. Series: "Brain Channel" [Professional Medical Education] [Show ID: 35262]


The Burden of Alzheimer’s Disease and Related Diseases in Vulnerable Populations

Worldwide 50 million people live with dementia. By 2040 over 70% of them will be living in the developing world. Dr. Shamiel McFarlane explores the social and economic cost of dementia around the world. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 34779]


Brain Health Promotion Strategies: Separating Reality-Based Hope From Hopeless Pseudo-Medicine

There are modifiable behaviors that may reduce the risk factor of Alzheimer's: vascular disease, sedentary lifestyle, depression/stress, diet factors and alcohol. Kaitlin Casaletto talks about the benefits of an active lifestyle and proper nutrition. Then Dr. Joanna Hellmuth looks at how to decode direct-to-consumer interventions - dietary supplements - and the rise of pseudo-medicine for dementia. She explains that supplements may or may not be safe and that manufacturers can make broad...


Treatment and Management of Patients with Neurodegenerative Disease: Current State of Science

Dr. Julio Rojas-Martinez discusses the pharmacological treatment of Alzheimer’s disease now and what is in development. Current approaches pursue early intervention in the dementia phase. Novel emerging strategies will likely accompany anti-amyloid and anti-tau approaches in the future. Then Sarah Dulaney, RN, describe dementia education, support, and non-pharmacological treatment strategies. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 34777]


Looking Beyond Alzheimer’s Disease: An Overview of Other Major Forms of Neurodegenerative Disease

Alzheimer’s disease is the most common but not the only cause of dementia throughout the lifespan. Dr.Salvatore Spina discusses frontotemporal dementias and how they differ. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 34776]


Diagnosing Alzheimer’s Disease: From Genetics Neuropathology to Common and Rare Clinical Manifestations of the Disease

Dr. Geroges Naasan explores the principal clinical syndromes of Alzheimer's Disease: memory, visual, language and frontal/executive. He also discusses neuropathology, genetic factors and modern biomarkers with colleagues from the UCSF Memory and Aging Center. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 34775]


Mouse and Human Induced Pluripotent Stem Cell Models of Autism Associated with Early Brain Overgrowth

Tony Wynshaw-Boris, MD, PhD describes his lab's efforts to use mouse and IPSC models to find commonalities that give insight into the complex disorder of autism. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Education] [Professional Medical Education] [Show ID: 34977]


A Brief Overview of the Neurodegenerative Diseases of the Brain

Neurologist Dr. Serggio Lanata explores the neurodegenerative disease of the brain, what they have in common and how they differ. alzheimer's is the most common neurodegenerative disease but there are several others including Parkinson's, Huntington Disease and others. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 34774]


Epilepsy Syndromes: An Evidence-based Era of Novel Treatments

Joseph Sullivan, MD, Neurology and Pediatrics, UCSF. Series: "Developmental Disabilities Update" [Health and Medicine] [Education] [Professional Medical Education] [Show ID: 34673]


Young Latino Scientists Working on Alzheimer's

More than 5 million Americans are currently diagnosed with Alzheimer’s disease, and that number is expected to triple by 2050, without prevention or cure. By 2060, the number of Latinos in the United States living with Alzheimer’s disease is projected to increase 832 percent — from 379,000 in 2012, to more than 3.5 million. Find out what UC San Diego is doing to both serve this community and catalyze the research careers of investigators from underrepresented groups. Series: "Brain Channel"...


Investigation About Alzheimer's Disease in the Latino Community (English Subtitles)

Alex Figueroa and Dr. Jose Soria-Lopez discuss clinical symptoms of Alzheimer's Disease and the need to include the Latino community in clinical research. Series: "Brain Channel" [Health and Medicine] [Science] [Show ID: 34416]


Investigación sobre la Enfermedad de Alzheimer en la Comunidad Latina

Este es el primer episodio en español de la Universidad de San Diego California sobre la investigación de la Enfermedad de Alzheimer Demencia en la comunidad latina. En este episodio Alex Figueroa y el Dr. Jose Soria-Lopez conversan sobre los síntomas clínicos y la necesidad de incluir la comunidad latina en investigaciones clínicas sobre esta enfermedad. Se mencionan maneras de combatir la enfermedad y recursos sociales que están disponibles para personas con esta enfermedad y familiares....


A Flaw in Modern-Day Alzheimer's Treatment

Rudolph Tanzi, PhD, of the Harvard Medical School describes a fundamental problem with modern-day treatment of Alzheimer's disease. Series: "Wellbeing " [Health and Medicine] [Show ID: 34243]


ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS

Sandrine Da Cruz, PhD and Jone López-Erauskin, PhD explain how ALS causing mutations in FUS inhibit intra-axonal protein synthesis and drive disease without nuclear loss of FUS function. This research appears in the journal Neuron. [Health and Medicine] [Science] [Show ID: 34203]