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The Peter Attia Drive

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English


Episodes

Mark and Chris Bell: steroids, powerlifting, addiction, diet, training, helping others, documentaries, and living your best life (EP.28)

11/12/2018
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In this episode, Mark and Chris Bell discuss their love of powerlifting, their unbelievable personal records, and what prompted the making of their now iconic film, Bigger, Stronger, Faster. They also very openly discuss steroid use, their tragic family history with addiction, the many inspirations that lead to their multifaceted success, and their dedication to having a positive impact on others in fitness and life. We discuss: Learn more at www.PeterAttiaMD.com Connect with Peter on ...

Duration:02:11:22

David Sinclair, Ph.D.: Slowing aging – sirtuins, NAD, and the epigenetics of aging (EP.27)

11/5/2018
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In this episode, David A. Sinclair, Ph.D., a Professor in the Department of Genetics at Harvard Medical School and co-Director of the Paul F. Glenn Center for the Biological Mechanisms of Aging, provides insight into why we age and how to slow its effects based on his remarkable work on the role of sirtuins and NAD in health and diseases. He also presents the case that stabilizing the epigenetic landscape may be the linchpin in counteracting aging and disease. We...

Duration:01:41:22

AMA #3: supplements, women’s health, patient care, and more (EP.26)

10/29/2018
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In this “Ask Me Anything” (AMA) episode, Peter answers a wide range of questions from readers and podcast listeners. Bob Kaplan, Peter’s head analyst, asks the questions. This also marks the first video release of the podcast. You can find it on YouTube (https://youtu.be/kzs7GgxR_FQ) and the website (peterattiamd.com/ama03). If you have any questions for the next AMA, please submit them to the AMA section on the website (peterattiamd.com). We discuss: Learn more at...

Duration:02:08:53

Scott Harrison: transformation, finding meaning, and taking on the global water crisis (EP.25)

10/22/2018
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We discuss: 3:458:001:15:001:28:001:54:002:01:00 Learn more at www.PeterAttiaMD.com Connect with Peter on Facebook | Twitter | Instagram.

Duration:02:18:39

Tom Dayspring, M.D., FACP, FNLA – Part V of V: Lp(a), inflammation, oxLDL, remnants, and more (EP.24)

10/19/2018
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In this five-part series, Thomas Dayspring, M.D., FACP, FNLA, a world-renowned expert in lipidology, and one of Peter's most important clinical mentors, shares his wealth of knowledge on the subject of lipids. In Part V, Peter and Tom talk about inflammation, endothelial health, and oxidative stress as they pertain to cardiovascular disease, and our attempts to monitor them using biomarkers. They also discuss a couple of very important risk factors that too few people (and doctors) know...

Duration:01:29:38

Tom Dayspring, M.D., FACP, FNLA – Part IV of V: Statins, ezetimibe, PCSK9 inhibitors, niacin, cholesterol and the brain (EP.23)

10/18/2018
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In this five-part series, Thomas Dayspring, M.D., FACP, FNLA, a world-renowned expert in lipidology, and one of Peter's most important clinical mentors, shares his wealth of knowledge on the subject of lipids. In Part IV, Peter and Tom review the history and current use of drugs to prevent cardiovascular disease. They also discuss why some drugs appear to be more effective than others, an in-depth conversation about niacin, cholesterol and brain health, and the futility of using CKs...

Duration:02:00:05

Tom Dayspring, M.D., FACP, FNLA – Part III of V: HDL, reverse cholesterol transport, CETP inhibitors, and apolipoproteins (EP.22)

10/17/2018
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In this five-part series, Thomas Dayspring, M.D., FACP, FNLA, a world-renowned expert in lipidology, and one of Peter's most important clinical mentors, shares his wealth of knowledge on the subject of lipids. In Part III, Peter and Tom dig into HDL, why "reverse cholesterol transport" is a lot more nuanced than what most of us are taught, lipid transport, apolipoproteins, and more. In addition, this episode highlights the complexity of HDL and a discussion about the CETP inhibitor...

Duration:01:04:12

Tom Dayspring, M.D., FACP, FNLA – Part II of V: Lipid metrics, lipid measurements, and cholesterol regulation (EP.21)

10/16/2018
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In this five-part series, Thomas Dayspring, M.D., FACP, FNLA, a world-renowned expert in lipidology, and one of Peter's most important clinical mentors, shares his wealth of knowledge on the subject of lipids. In Part II, Tom provides a 101 on lipids and lipoproteins. Tom and Peter also discuss the history and techniques used to measure lipoproteins, and more. We discuss: 1:305:156:4515:15 Learn more at www.PeterAttiaMD.com Connect with Peter on Facebook | Twitter | ...

Duration:01:26:54

Thomas Dayspring, M.D., FACP, FNLA – Part I of V: an introduction to lipidology (EP.20)

10/15/2018
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In this five-part series, Thomas Dayspring, M.D., FACP, FNLA, a world-renowned expert in lipidology, and one of Peter's most important clinical mentors, shares his wealth of knowledge on the subject of lipids. Part I serves as an introduction to Tom, his work, and an overview of lipid terminology. We discuss: Learn more at www.PeterAttiaMD.com Connect with Peter on Facebook | Twitter | Instagram.

Duration:01:14:27

Dave Feldman: stress testing the lipid energy model (EP.19)

10/8/2018
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In this episode, Dave Feldman, discusses his journey from software engineer to n=1 experimenter, his experience with low-carbohydrate diets, and his hypothesis that cholesterol levels are influenced by energy metabolism. We discuss: 5:0015:0018:3020:001:41:001:45:002:10:002:53:00 Learn more at www.PeterAttiaMD.com Connect with Peter on Facebook | Twitter | Instagram.

Duration:03:10:15

Richard Isaacson, M.D.: Alzheimer’s prevention (EP.18)

10/1/2018
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In this episode, Richard Isaacson, a neurologist and director of the Alzheimer’s Prevention Clinic at Weill Cornell Medicine and NewYork-Presbyterian, discusses strategies for staving off Alzheimer’s disease. Richard shares a wealth of insight for people who want to know more about Alzheimer’s and what you can do to help yourself and your loved ones – starting today and continuing throughout the entire lifespan. We discuss: 8:0018:20APOE1:13:00MTHFR1:45:00 Learn more at...

Duration:02:24:17

Mike Trevino: life-lessons from ultra-endurance, mindset, hard work, and removing limitations (EP.17)

9/24/2018
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In this episode, ultra-endurance athlete and entrepreneur, Mike Trevino, discusses the lessons he’s learned from his remarkable athletic feats, and the training required to reach them. Not only is Mike’s advice practical for those looking to take their endurance training to the next level, but his lessons and insight are extraordinarily applicable to living everyday life. We discuss: 6:3016:001:03:001:15:001:22:00 Learn more at www.PeterAttiaMD.com Connect with Peter on Facebook | ...

Duration:01:56:05

Formula 1 (with Paul Conti): the best drivers, Ayrton Senna, and the cautionary tales of driven individuals (EP.16)

9/20/2018
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In this bonus episode, Peter and med school colleague (and brilliant psychiatrist) Paul Conti reminisce on their favorite moments in Formula 1 history, their deep admiration for the late Ayrton Senna, and the remarkable careers of their all-time favorite drivers. Paul also helps to illuminate the psychological components that made the luminary drivers great, and the cautionary lessons we can take from their incredible lives. We discuss: 3:459:5012:5517:4523:30 Learn more at...

Duration:01:03:12

Paul Conti, M.D.: trauma, suicide, community, and self-compassion (EP.15)

9/17/2018
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In this episode, psychiatrist Paul Conti, M.D. discusses the impact of untreated trauma, the rising rate of suicide, and the influence of modern society on mental health, to name a few important topics covered. Paul also talks about how to deal with these challenges for yourself, your loved ones, and the community at large. We discuss: Learn more at www.PeterAttiaMD.com Connect with Peter on Facebook | Twitter | Instagram.

Duration:02:05:46

Robert Lustig, M.D., M.S.L.: fructose, processed food, NAFLD, and changing the food system (EP.14)

9/10/2018
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In this episode, Rob Lustig — a researcher, an expert in fructose metabolism, and a former pediatric endocrinologist — discusses what’s wrong with the current food environment, and what we can do to reduce our chances of becoming part of the obesity, diabetes, metabolic syndrome, and nonalcoholic fatty liver disease (NAFLD) epidemics. Rob recently earned a Master of Studies in Law because he believes that educating people about sugar from a scientific standpoint is only half the equation:...

Duration:01:23:16

Brett Kotlus, M.D.: How to look younger while you live longer (EP.13)

9/3/2018
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This episode explores the question of how we can maintain a naturally youthful look as we get older. Brett — a New York City oculofacial plastic surgeon who specializes in both non-surgical and surgical cosmetic and reconstructive procedures of the eyes and face — shares some remarkably practical advice on everything from the most extensive procedural options, down to the simple steps one can do themselves, starting today, that can make a tremendous impact. Brett also discusses how to pick a...

Duration:01:48:41

Corey McCarthy: Overcoming trauma, dealing with shame, finding meaning, changing the self-narrative, redemption, and the importance of gratitude (EP.12)

8/27/2018
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Corey and Peter met when they visited North Kern State Prison in California together as volunteers for Defy Ventures. Peter was moved by Corey’s remarkable story, who is a former inmate himself, and realized he had to have him on the podcast to share his experiences with a wider audience. You’ll almost assuredly take away something very important from listening to this episode. Understanding how your experiences can define you, what forgiveness means of both yourself and others, and how good...

Duration:02:26:59

AMA #2: the Nothingburger — results from Peter’s week-long fast between two weeks of nutritional ketosis — and answering questions on all things fasting (EP.11)

8/23/2018
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Consider this episode a cross between an ask me anything (AMA) and a show-and-tell. Peter discusses his fasting experiment in great detail and answers questions from listeners and readers. We discuss: Learn more at www.PeterAttiaMD.com Connect with Peter on Facebook | Twitter | Instagram.

Duration:01:50:31

Matt Kaeberlein, Ph.D.: rapamycin and dogs — man’s best friends? — living longer, healthier lives and turning back the clock on aging, and age-related diseases (EP.10)

8/20/2018
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Matt is someone who is deeply interested in understanding the biology of aging. Why do we age? What happens to us as we age? What are the things we can do to slow the aging process? How can we delay or prevent the onset of age-related diseases? These are all questions that Matt thinks deeply about, and explores these questions with his research at the University of Washington. He is currently investigating many of these questions through the Dog Aging Project and the compound rapamycin—the...

Duration:01:32:44

David Sabatini, M.D., Ph.D.: rapamycin and the discovery of mTOR — the nexus of aging and longevity? (EP.09)

8/13/2018
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In this episode, my good friend David Sabatini delves into his extensive work with the mechanistic target of rapamycin—better known as mTOR—and rapamycin. The compound rapamycin is the only known pharmacological agent to extend lifespan all the way from yeast to mammals—across a billion years of evolution. David, a professor of biology and a member of the Whitehead Institute at MIT, shares his remarkable journey and discovery of mTOR in mammalian cells and its central role in nutrient...

Duration:01:11:21