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Haematology Podcast

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A podcast exploring the Haematology speciality, made for nurses, junior doctors and allied healthcare professionals.

A podcast exploring the Haematology speciality, made for nurses, junior doctors and allied healthcare professionals.
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United Kingdom


A podcast exploring the Haematology speciality, made for nurses, junior doctors and allied healthcare professionals.




+44 7788 171583


S01E10 POEMS and Waldenström’s macroglobulinaemia with Shirley D'sa

In our final podcast of the series we discuss with Dr Shirley D'Sa plasma cell function and disorders including POEMS and Waldenström’s macroglobulinaemia. Dr D'sa is a haematologist with a specialist interest in Waldenström’s macroglobulinaemia and associated disorders, myeloma and POEMS syndrome at UCLH. UCLH currently manages one of the largest reported group of POEMS patients in Europe, with approximately 75 people attending the clinic. POEMS syndrome is a rare condition caused by the...


S01E09 Introduction to Allogeneic Transplantation with Ben Carpenter

For our penultimate podcast of the series, we are joined by Ben Carpenter, a Transplant Consultant at UCLH. We start by discussing the history of Allogeneic transplantation through the 20th Century, and how transplants are matched. We the move into the rationale for the use of different types of conditioning and sources of haematopoietic progenitor cells. Potential areas of refinement, and new directions of travel for immunotherapies are explored at the end. Transplantation is a large area,...


S01E08 Myelodysplastic Syndromes with Beth Payne

Beth Payne is a Senior Clinical Researcher at the UCL Cancer Institute, where she is Research Group leader in bone marrow failure and myelodysplastic syndromes. Beth is also a Leukaemia Consultant at UCLH. The title, Myelodysplastic Syndromes (MDS), covers a diverse group of diseases, with far more genetic mutations than many Haematological disorders. Ward staff are familiar with treating patients with MDS when it transforms to Acute Myeloid Leukaemia (AML), so we asked Beth to give us an...


S01E07 Cancer Biology With Marc Mansour

Welcome to the formal launch episode of the 'Bolus' podcast! In this episode we are joined by Marc Mansour, a consultant haematologist specialising in the treatment of patients with Acute Leukaemias and Myelodyspastic Syndromes at UCLH. He is the research group leader of the Leukaemia Biology group at the UCL Cancer Institute, focusing on T-cell acute lymphoblastic leukaemia (T-ALL) and acute myeloid leukaemia (AML), and in particular on oncogenic transcription factor complexes, mechanisms...


S01E06 Thrombotic Thrombocytopenic Purpura with Marie Scully

Thrombotic Thrombocytopenic Purpura (TTP) is a rare type of Microangiopathic Haemolytic Anaemia (MAHA). UCLH Haematology has long been a leading centre in the treatment of TTP, so we met up with a renowned authority on the subject, Professor Marie Scully, to discuss the disease. We run through the development of this specialism at UCLH, the disease pathophysiology and current treatment options. Much of the discussion is grounded in the importance of appropriate nursing care and monitoring of...


S01E05 Thalassaemia with John Porter

Our discussion covers the background, pathophysiology and historic treatment options for patients with Thalassaemia. A new drug, LentiGlobin, has been used recently in clinical trials at UCLH. It involves genetically modifying autologous stem cells to produce sufficient Red blood cells, and takes away the need for blood transfusions. Prof John Porter is a well-recognised consultant haematologist and expert on red cell haematology. He is Professor of Haematology at UCL and Head of the Red...


S01E03 Overview of Lymphoma with Will Townsend

Dr Will Townsend is a UCLH Lymphoma Consultant and conducts Phase 1 clinical trials at the UCLH Clinical Research Facility. Our discussion covers the basics of Lymphoma, unpicking the different types, grades, classifications and treatments. At the end we touch upon a current clinical trial involving the use of T-cell Bispecific Antibodies, an off-the-shelf drug that can recruit the patient’s immune system to attack malignant B-cells.


S01E02 Cancer Clinical Trials with Leigh Wood

UCLH NHS Foundation Trust and University College London have a close academic and clincal partnership. In the field of immunotherapy, this partnership has led to UCL being ranked second in the world and top in Europe for the number of inventions and patent applications made in relation to CAR T-cells. In 2018, more CAR T-cells were administered at UCLH than in the rest of Europe combined. To help explore these developments we asked Leigh Wood, the Cell Therapy Team Lead from the Cancer...


S01E01 Immunotherapy and CAR-T Cells with Emma Morris

In discussion with Emma Morris, Professor of Clinical Cell and Gene Therapy at University College London. For decades immunotherapies, like vaccines and allogeneic stem cell transplantation, have harnessed the ability of the immune system to fight diseases. More recently, genetically modified immune cells known as CAR T-Cells have been designed to recognise and attack cancer cells that display tell-tale markers, bringing new hopes of cure in previously resistant blood cancers. Further...


S01E04 Acute Myeloid Leukaemia with Andrew Wilson

A discussion about Acute Myeloid Leukaemia, from diagnosing to devising a personalised treatment plan. We run through the challenges in the initial treatment of APML, namely differentiation syndrome and DIC, and delve briefly into functional neutropenia. Many thanks to Dr Andrew Wilson for his valuable insights. Andrew is a consultant haematologist at UCLH with a special interest in laboratory haematology and cancer education. Clinically he works in the MPN service and is one of the...