TGen North's Dr. David Engelthaler discusses Valley Fever. We learn why Arizona - with nearly 65% of all Valley Fever cases in the U.S.- is the perfect hotbed for research into this debilitating and potentially lethal disease, and how TGen North is tracking this warm-climate invader and adapting today's technology to provide much needed answers to this age-old problem.
Patrick Pirrotte, Ph.D., Assistant Professor of the Cancer and Cell Biology Division and the Director of TGen's Collaborative Center for Translational Mass Spectrometry discusses the role of proteomics in cancer research, and finding new targets for cancer treatment.
TGen Assistant Professor, Dr. Will Hendricks, discusses comparative oncology, a field of study that in recent years has gained in popularity, as it seeks to integrate information from naturally occurring cancers in pets into what we know about the biology of cancer in humans.
MindCrowd, launched seven years ago by Dr. Matthew Huentelman, studies the healthy brain. At its core, MindCrowd offers a new way approach scientific research to learn how the brain functions and how genetics influences memory.
Microbes out-number the genes in your DNA by more than 1,000 to 1 and together they make up what is known as your microbiome. TGen’s Dr. Sarah K. Highlander, a research professor in the Pathogen and Microbiome Division at TGen North and director of the Clinical Microbiome Service Center, works to understand the microbiome and how it is helping scientists better understand cancer, diabetes and a host of other conditions, including traveler’s diarrhea.
Dr. Glen Otero, a 20 year veteran of life science industry and an expert in high-performance computing, discusses artificial intelligence, or A.I., and how it addresses the computational needs of the biomedical research community by executing tasks more rapidly and without human error in a fraction of the time. Today, A.I. is used to process complex genomic data sets to accelerate delivery of personalized treatments for cancer and other diseases by turning raw genomic data —such as a human...
In medicine, a biomarker is anything used to determine the presence or development of a particular disease or biological state. They can be used to determine if an injury or disease has occurred, or even if a therapy is working. In this episode, Dr. Kendall Van Keuren-Jensen, a Professor in TGen Neurogenomics Division and Co-Director of TGen’s Center for Noninvasive Diagnostics, discusses how her team is working on ways to use biomarkers — in this case the molecular readout of RNA — as a...
Nature vs. nurture? How about nature and nature? Dr. Candace Lewis, a postdoctoral fellow in the Huentelman lab at TGen, walks us through a biological regulatory framework known as epigenomics that changes the behavior of our cells due to our life experiences. Dr. Lewis also discusses the resurgence in psychedelic assisted therapy to treat depression and trauma, and her work in Autism.
James Lowey, TGen's Chief Information Officer, discusses how high-performance computing has revolutionized genomics and how our partnership with Dell has created a powerful platform to transform health.
Dr. Jonathan Keats discusses how multiple myeloma can be multiple cancers from a genetic standpoint. Through his work with the Multiple Myeloma Research Foundation's CoMMpass Study, Dr. Keats' team has sequenced 1,150 patients from 90 sites worldwide. What does this mean for patients?
TGen's Center for Rare Childhood Disorders provides genetic testing to give hope and answers to rare disease patients. As part of their summer project, our Helios Scholars at TGen interns, Hannah and Morgan, interviewed one of our families about their years-long journey to a diagnosis.