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Episodes

Episode 18: Stirring Up A Whole Lot of Science Around Valley Fever

8/20/2019
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TGen North's Dr. David Engelthaler discusses Valley Fever. We learn why Arizona - with nearly 65% of all Valley Fever cases in the U.S.- is the perfect hotbed for research into this debilitating and potentially lethal disease, and how TGen North is tracking this warm-climate invader and adapting today's technology to provide much needed answers to this age-old problem.

Duration:00:10:59

Episode 17: A Deeper Look at Proteomics

7/19/2019
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Patrick Pirrotte, Ph.D., Assistant Professor of the Cancer and Cell Biology Division and the Director of TGen's Collaborative Center for Translational Mass Spectrometry discusses the role of proteomics in cancer research, and finding new targets for cancer treatment.

Duration:00:04:38

Episode 16: Comparative Oncology Provides Deeper Insight into Cancer

6/20/2019
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TGen Assistant Professor, Dr. Will Hendricks, discusses comparative oncology, a field of study that in recent years has gained in popularity, as it seeks to integrate information from naturally occurring cancers in pets into what we know about the biology of cancer in humans.

Duration:00:09:20

Episode 15: MindCrowd—A Study on how the Healthy Brain Works

5/29/2019
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MindCrowd, launched seven years ago by Dr. Matthew Huentelman, studies the healthy brain. At its core, MindCrowd offers a new way approach scientific research to learn how the brain functions and how genetics influences memory.

Duration:00:11:22

Tiny Microbes A Big Deal for Dr. Sarah Highlander

4/16/2019
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Microbes out-number the genes in your DNA by more than 1,000 to 1 and together they make up what is known as your microbiome. TGen’s Dr. Sarah K. Highlander, a research professor in the Pathogen and Microbiome Division at TGen North and director of the Clinical Microbiome Service Center, works to understand the microbiome and how it is helping scientists better understand cancer, diabetes and a host of other conditions, including traveler’s diarrhea.

Duration:00:09:37

Episode 13: AI and Big Data with Dr. Glen Otero

3/20/2019
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Dr. Glen Otero, a 20 year veteran of life science industry and an expert in high-performance computing, discusses artificial intelligence, or A.I., and how it addresses the computational needs of the biomedical research community by executing tasks more rapidly and without human error in a fraction of the time. Today, A.I. is used to process complex genomic data sets to accelerate delivery of personalized treatments for cancer and other diseases by turning raw genomic data —such as a human...

Duration:00:08:07

Episode 12: TGen Talks — Tracking Neurodegenerative Disorders With Biomarkers

1/29/2019
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In medicine, a biomarker is anything used to determine the presence or development of a particular disease or biological state. They can be used to determine if an injury or disease has occurred, or even if a therapy is working. In this episode, Dr. Kendall Van Keuren-Jensen, a Professor in TGen Neurogenomics Division and Co-Director of TGen’s Center for Noninvasive Diagnostics, discusses how her team is working on ways to use biomarkers — in this case the molecular readout of RNA — as a...

Duration:00:09:39

Episode 11: Outside Influence: Stimuli, Epigenomics, and Changing Cell Behavior

12/13/2018
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Nature vs. nurture? How about nature and nature? Dr. Candace Lewis, a postdoctoral fellow in the Huentelman lab at TGen, walks us through a biological regulatory framework known as epigenomics that changes the behavior of our cells due to our life experiences. Dr. Lewis also discusses the resurgence in psychedelic assisted therapy to treat depression and trauma, and her work in Autism.

Duration:00:08:03

Episode 10: TGen Talks Takeover - Your Best Advice

10/25/2018
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Helios Scholar Mario Mosqueda asked 10 TGen scientists for their best career advice in an insightful discussion on charting a path in science.

Duration:00:19:33

Did You Know? Postdocs Are People Too

9/17/2018
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Did You Know? There are fellows - and ladies - that work in the lab to learn how to lead a lab. They're called 'postdocs.'

Duration:00:03:39

Episode 9: Meet Steve, Pancreatic Cancer Survivor

8/10/2018
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Steve, a four-year pancreatic cancer, survivor shares his story of hope.

Duration:00:12:54

Episode 8: Students Takeover TGen Talks - Discovery Ensues!

7/26/2018
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Students from the inaugural TGen Bioscience Leadership Academy took over the TGen Talks podcast to discuss what they learned during their two-week, immersive summer experience at TGen.

Duration:00:11:15

Did You Know? Single-Cell Sequencing

6/14/2018
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Single-Cell Sequencing promises to bring more precision to 'precision medicine.' Learn how this new technique could revolutionize diagnosis and treatment from Dr. Jonathan Keats.

Duration:00:04:48

Episode 7: Computing Horsepower with James Lowey

5/1/2018
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James Lowey, TGen's Chief Information Officer, discusses how high-performance computing has revolutionized genomics and how our partnership with Dell has created a powerful platform to transform health.

Duration:00:10:02

Episode 6: Mom-To-Be Makes Ovarian Cancer Discovery

4/17/2018
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Dr. Jessica Lang, a mother-to-be, discusses a new treatment discovery for ovarian cancer, the deadliest reproductive cancer.

Duration:00:09:51

Episode 5: Understanding Multiple Myeloma

3/22/2018
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Dr. Jonathan Keats discusses how multiple myeloma can be multiple cancers from a genetic standpoint. Through his work with the Multiple Myeloma Research Foundation's CoMMpass Study, Dr. Keats' team has sequenced 1,150 patients from 90 sites worldwide. What does this mean for patients?

Duration:00:09:32

Did You Know? Computer Science vs Lab Science

3/19/2018
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Did You Know? Bioscience is as much about computer science as it is about laboratory science! Make yourself smarter in 2 minutes with our latest TGen Talks podcast!

Duration:00:02:18

Episode 4: What Is CAR T Therapy?

2/22/2018
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Dr. John Altin explains how a patient's own immune cells can be transformed into cancer-killers through CAR T therapy — and what this means for the future of cancer treatment.

Duration:00:12:10

Episode 3: The Diagnostic Odyssey

1/22/2018
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TGen's Center for Rare Childhood Disorders provides genetic testing to give hope and answers to rare disease patients. As part of their summer project, our Helios Scholars at TGen interns, Hannah and Morgan, interviewed one of our families about their years-long journey to a diagnosis.

Duration:00:15:30

Did You Know? Arsenic vs Glioblastoma

1/9/2018
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Arsenic is a poison, commonly associated with murder mysteries, but did you know that it can be an effective cancer-killer? Learn more from disease detective Dr. Harshil Dhruv at TGen.

Duration:00:03:32