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2 per cent Chlorhexidine vs. Iodine for central line placement in preterm infants: a RCT

Professor of Neonatology Colm O'Donnell, University College Dublin, and Neonatologist Emily Kiernan, British Colombia Women's Centre, Vancouver, discuss a randomised trial on skin cleansing in preterm neonates, Clorhexidine vs Iodine, with Jonathan Davis, Associate Editor of ADC FN. Read the free paper “2% chlorhexidine–70% isopropyl alcohol versus 10% povidone–iodine for insertion site cleaning before central line insertion in preterm infants: a randomised trial” here:...


The Archimedes Podcast March 2018: incongruity, zinc and guessing

This month has work from lower/middle-income countries offering to impact up care both within those resource settings, and the high-income countries that usually provide the bulk of Archi’s feeds. There are questions about the validity of 'PCV/3' as a haemoglobin estimate: and uncertainty about if zinc should be given to children with diarrhoea on Salisbury Plain: We also have the horror of spelling tests rearing their head. And...


Atoms: the ADC March 2018 highlights with Nick Brown

Editor-in-Chief of ADC Nick Brown brings you the monthly Atoms - the highlights of the March 2018 issue in a very short podcast. Read the highlights on the Archives of Disease in Childhood website:


Developmental effects of carbon dioxide targets in extremely preterm infants. The PHELBI follow up

Professor Ulrich Thome, Division of Neonatology, University Hospital for Children and Adolescents, University of Leipzig, Germany, joins Jonathan Davis to discuss the paper "Neurodevelopmental outcomes of extremely low birthweight infants randomised to different PCO2 targets: the PHELBI follow-up study". The Associate Editor of ADC Fetal and Neonatal edition spoke with the author at the Joint European Neonatal Societies meeting in Venice. Read the paper included in the September's 2017...


The Archimedes Podcast: regret and irrational decisions

It’s Musical Month in Archimedes as the podcast explores the nature of regret and rationality, has a snippet of song, and then goes on to more seriously see if Vitamin D can help with Growing pains. Read the article: Also in this podcast, should you swallow or dribble antibiotics for ear infections in children with grommets? More details here: More on the ADC’s January 2018 Archimedes here:...


Atoms: the ADC February 2018 highlights with Nick Brown

Editor-in-Chief of ADC Nick Brown brings you the monthly Atoms - the highlights of the February 2018 issue in a just over 5-minute podcast. Read the highlights on the Archives of Disease in Childhood website:


Delayed cord clamping in preterm birth. The CORD trial

Associate Editor of ADC Fetal and Neonatal edition Jonathan Davis discusses delayed cord clamping in preterm birth with Jon Dorling (Nottingham Clinical Trials Unit, Queen’s Medical Centre, University of Nottingham, UK), Sam Oddie (Centre for Reviews and Dissemination, Hull York Medical School, University of York, UK). Related articles: Randomised trial of cord clamping and initial stabilisation at very preterm birth - Editorial: Timing is everything -...


Atoms: the ADC January 2018 highlights with Nick Brown

Nick Brown brings you the monthly Atoms - the highlights of the January 2018 issue in a few words. Read the highlights on the ADC website:


The Archimedes Podcast: the safety of ACE-inhibitors in children

The January 2018 Archimedes podcast contains all sorts of fun looking at the safety of ACE-inhibitors in children -, squaring up to the Rule of Three (malaria tests in this instance) - - and we also talk validation and revalidation in an attempt to predict the future The ADC Archimedes podcast, home of the best evidence-paediatrics chat, is presented by Bob Phillips, the...


The Archimedes Podcast: overdiagnosis - good or bad?

Stepping back from doing things is the theme of the December 2017’s Archimedes podcast with questions of how not to engage in pointless practices at the forefront of our minds. Read about the lack of advantage of high-dose aspirin in Kawasaki disease here - - and follow-up x-rays for round pneumonia here - -, whose leading author, Patrick McCrossan (Paediatrics, Royal Belfast Hospital for Sick Children,...


Introducing ADC's new editors. The highlights of the December 2017 issue with Nick Brown

Nick Brown is the new Editor-in-Chief of Archives and Disease in Childhood. Listen to his vision for the journal in this podcast, which will bring you Atoms - the highlights of this issue in a few words. Read the highlights of the December 2017 issue here:


The Archimedes Podcast: necrotising varicella and lumbar punctures in meningitis

The October 2017’s Archimedes podcast includes answers to “Have you ever wondered if it might be worth trying to do an Archi?” and “What came first, the ‘brufen or the necrotic flesh?” along with cerebrospinal fluid (CSF) analysis and musings on the nature of evidence-based medicine. Read more about varicella-zoster virus (VZV) and non-steroidal anti-inflammatories here - - and how to interpret delayed CSF results here -...


The Archimedes Podcast: plant oils for babies; better sleep in children with intellectual disability

In the September 2017 podcast, we have two evidence-based cases, an exposition of shared decision making, and a zingier feel to the podcast which we’d like you to appreciate fully. You can read the full articles on plant oils for baby soft skin here - - and melatonin for sleep disturbances in children with intellectual disability here - - along with our blog discussing all manner of EBM things at


The role of prenatal steroids at 34–36 weeks of gestation

Professor of Obstetrics and Gynaecology at University of Cambridge Gordon Smith discusses a leading article from the July Edition of the Archives of Disease in Childhood Fetal and Neonatal edition with Associate Editor Jonathan Davis. The article states that administration of betamethasone to women with threatened preterm delivery at 34–36 weeks of gestational age to reduce the risk of neonatal respiratory morbidity may cause long-term harm through effects on the infant’s brain. This...


Thin-for-gestational age infants and neurodevelopmental outcome

Associate Editor of Archives of Disease in Childhood Fetal and Neonatal edition Jonathan Davis is joined by two authors included in the May 2017's issue of the journal: Deirdre Murray and Louise Kenny (both from the Irish Centre for Fetal and Neonatal Translational Research, Cork University Maternity Hospital, Ireland). They are two of the authors of ‘Thin-for-gestational age infants are at increased risk of neurodevelopmental delay at 2 years’. Read the full article:...


The Archimedes Podcast, August 2017: towards evidence based medicine for paediatricians

We're back! The ADC Archimedes podcast, home of the best evidence-paediatrics chat in Soundcloud has been reborn. This month, Bob Phillips, the Social Media and Archimedes Editor, talks runny poo and how to reduce it (see 'Probiotics in acute infectious diarrhoea: should we run with it?' here and what to pre-med a prem in the own words of Tim van Hasselt, Birmingham Children’s Hospital, (read 'What is the best sedative to give as premedication for...


Global Child Health - Strengthening the paediatric workforce for better health outcomes

Paediatric training and the practice of paediatrics is built on the bedrock of ensuring best possible health outcomes for all children, optimising opportunity for those without full health and contributing to a voice, in advocacy, for children. In the world’s high-income countries (HICs), child health outcomes are comparatively good, and the paediatric workforce well trained to manage the health issues of children. Paediatric training and continuing professional development is generally...


Automated Control of Inspired Oxygen in the Preterm Infants

The automated control of inspired oxygen in the preterm infants is discussed in this podcast. Associate Editor of Archives of Disease in Childhood Fetal and Neonatal edition Jonathan Davis is joined by two authors included in the January 2017 issue of the journal: Christian Poets (Department of Neonatology, University Children's Hospital, Tübingen, Germany) and Peter Dargaville (Department of Paediatrics, Royal Hobart Hospital, Hobart, Tasmania, Australia). Find more details of the ADC...


Global Child Health - An informal forum is driving innovation in Pakistan

The Critical Creative Innovative Thinking (CCIT) is a forum formed at the Aga Khan University (AKU) in Karachi, Pakistan, aiming to provide an arena conducive to lateral thinking and to equip biomedical professionals with the skill set to enable and promote creativity and innovation in paediatric care for resource-limited backgrounds. The promoter of this project, Asad Mian, (Departments of Emergency Medicine, Paediatrics & Child Health, AKU) tells global commissioning editor of ADC, Nick...


The Archimedes Podcast, March 2017

Bob Philips introduces the latest Archimedes podcast. Follow the links below to read the articles. Towards evidence based medicine for paediatricians - QUESTION 1: What is the risk of a repeat reaction to amoxicillin or a cephalosporin in children with a history of a non-immediate reaction to amoxicillin? - QUESTION 2: Does prophylactic nystatin prevent invasive fungal infections in immunocompetent critically ill...


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