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Impact of Specialized Inpatient IBD Care on Outcomes of IBD Hospitalizations

10/31/2016
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Impact of Specialized Inpatient IBD Care on Outcomes of IBD Hospitalizations: A Cohort Study Law, Cindy C. Y. MD; Sasidharan, Saranya MD; Rodrigues, Rodrigo MD; Nguyen, Deanna D. MD; Sauk, Jenny MD; Garber, John MD; Giallourakis, Cosmas MD; Xavier, Ramnik MD, PhD; Khalili, Hamed MD, MPH; Yajnik, Vijay MD, PhD; Ananthakrishnan, Ashwin N. MD, MPH Background: The management of inflammatory bowel diseases (IBDs; Crohn's disease, ulcerative colitis) is increasingly complex. Specialized care has...

Duration: 00:03:29


Dry Eye Disease: Effect of Re-esterified Omega-3 Supplementation

10/14/2016
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Effect of Oral Re-esterified Omega-3 Nutritional Supplementation on Dry Eyes Alice T. Epitropoulos, MD, Eric D. Donnenfeld, MD, Zubin A. Shah, MPH, Edward J. Holland, MD, Michael Gross, MD, William J. Faulkner, MD, Cynthia Matossian, MD, Stephen S. Lane, MD, Melissa Toyos, MD, Frank A. Bucci, Jr, MD, and Henry D. Perry, MD Cornea Volume 35, Number 9, September 2016 Abstract: Purpose: To assess the effect of oral re-esterified omega-3 fatty acids on tear osmolarity, matrix...

Duration: 00:05:29


HPV Vaccine: A Systematic Review of 10 Years of Real-World Experience

10/11/2016
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Host: Susan J. Wysocki, WHNP, FAANP Impact and Effectiveness of the Quadrivalent Human Papillomavirus Vaccine: A Systematic Review of 10 Years of Real-world Experience Clinical Infectious Disease 16 Aug 15;63(4):519-27. doi: 10.1093/cid/ciw354. Epub 2016 May 26. Garland SM1, Kjaer SK2, Muñoz N3, Block SL4, Brown DR5, DiNubile MJ6, Lindsay BR6, Kuter BJ6, Perez G7, Dominiak-Felden G8, Saah AJ6,Drury R8, Das R6, Velicer C6. Abstract: Prophylactic human papillomavirus (HPV) vaccination...

Duration: 00:04:30


Cell Death and Differentiation: A Novel Treatment of Cystic Fibrosis Acting On-Target

8/1/2016
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A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR Tosco A1, De Gregorio F1, Esposito S2, De Stefano D2, Sana I2, Ferrari E2, Sepe A1, Salvadori L1, Buonpensiero P1, Di Pasqua A1, Grassia R3, Leone CA3,Guido S4, De Rosa G5, Lusa S6, Bona G7, Stoll G8,9,10,11, Maiuri MC9, Mehta A12, Kroemer G9,13,14,15,16,17, Maiuri L2,7, Raia V1. Cell Death Differ. 2016 Aug;23(8):1380-93. doi:...

Duration: 00:03:30


Journal of Cystic Fibrosis: Microbial Colonization and Lung Function in Adolescents With Cystic Fibrosis

8/1/2016
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Microbial colonization and lung function in adolescents with cystic fibrosis Hector A1, Kirn T1, Ralhan A1, Graepler-Mainka U1, Berenbrinker S1, Riethmueller J1, Hogardt M2, Wagner M3, Pfleger A3, Autenrieth I4, Kappler M5, Griese M5, Eber E3, Martus P6, Hartl D7. J Cyst Fibros. 2016 May;15(3):340-9. doi: 10.1016/j.jcf.2016.01.004. Epub 2016 Feb 5. Interpretation: Patients with cystic fibrosis suffer from chronic progressive pulmonary disease, driven by cycles of airway infection and...

Duration: 00:02:30


Journal of Cystic Fibrosis: Efficacy and Safety of Levofloxacin Inhalation Solution (APT-1026) in Stable Cystic Fibrosis Patients

8/1/2016
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A phase 3, multi-center, multinational, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of levofloxacin inhalation solution (APT-1026) in stable cystic fibrosis patients Flume PA1, VanDevanter DR2, Morgan EE3, Dudley MN3, Loutit JS3, Bell SC4, Kerem E5, Fischer R6, Smyth AR7, Aaron SD8, Conrad D9, Geller DE10,Elborn JS11. J Cyst Fibros. 2016 Jul;15(4):495-502. doi: 10.1016/j.jcf.2015.12.004. Epub 2016 Feb 4. Interpretation: In this study published in...

Duration: 00:03:30


Individual detection of 14 high-risk HPV genotypes by the PapType test for the prediction of high-grade cervical lesions

7/29/2016
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Individual detection of 14 high-risk HPV genotypes by the PapType test for the prediction of high-grade cervical lesions Cuzick J1, Ho L2, Terry G2, Kleeman M2, Giddings M2, Austin J2, Cadman L2, Ashdown-Barr L2, Costa MJ2, Szarewski A2. J Clin Virol. 2014 May;60(1):44-9. doi: 10.1016/j.jcv.2014.02.002. Epub 2014 Feb 14. Review by Mark H. Einstein, MD, MS Interpretation: A recent article published by Cuzick and colleagues in the Journal of Clinical Virology has helped clarify the value of...

Duration: 00:05:30


A study of HPV typing for the management of HPV-positive ASC-US cervical cytologic results

7/28/2016
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Host: Thomas C. Wright, Jr., MD A study of HPV typing for the management of HPV-positive ASC-US cervical cytologic results Schiffman M1, Vaughan LM2, Raine-Bennett TR3, Castle PE4, Katki HA5, Gage JC5, Fetterman B6, Befano B7, Wentzensen N5. Gynecol Oncol. 2015 Sep;138(3):573-8. doi: 10.1016/j.ygyno.2015.06.040. Epub 2015 Jul 4. Reviewed by: Thomas C. Wright Jr., MD Interpretation: HPV testing is now a well-established as an integral component of cervical cancer screening. In the US,...

Duration: 00:04:29


The Lancet: Postural Modification to the Standard Valsalva Maneuver for Emergency Treatment of Supraventricular Tachycardias (REVERT)

9/4/2015
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Postural modification to the standard Valsalva manoeuvre for emergency treatment of supraventricular tachycardias (REVERT): a randomised controlled trial Andrew Appelboam, FRCEM, Adam Reuben, FRCEM, Clifford Mann, FRCEM, James Gagg, FRCEM, Prof Paul Ewings, PhD, Andrew Barton, MSc, Trudie Lobban, MRCP, Mark Dayer, FRCP, Jane Vickery, MSc, Prof Jonathan Benger, MD on behalf of the REVERT trial collaborators The Lancet. 2015; DOI:10.1016/S0140-6736(15)61485-4 Published Online: 24 August 2015...

Duration: 00:03:00


NEJM: Outcomes of Daytime Procedures Performed by Attending Surgeons after Night Work

9/4/2015
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Outcomes of Daytime Procedures Performed by Attending Surgeons after Night Work Anand Govindarajan, M.D., David R. Urbach, M.D., Matthew Kumar, M.Sc., Qi Li, M.Sc., Brian J. Murray, M.D., David Juurlink, M.D., Ph.D., Erin Kennedy, M.D., Ph.D., Anna Gagliardi, Ph.D., Rinku Sutradhar, Ph.D., and Nancy N. Baxter, M.D., Ph.D. N Engl J Med 2015; 373:845-853 DOI: 10.1056/NEJMsa1415994 August 27, 2015 Background: Sleep loss in attending physicians has an unclear effect on patient outcomes. In...

Duration: 00:03:29


JAMA: Noninvasive Prenatal Testing and Incidental Detection of Occult Maternal Malignancies

9/4/2015
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Noninvasive Prenatal Testing and Incidental Detection of Occult Maternal Malignancies Diana W. Bianchi, MD; Darya Chudova, PhD; Amy J. Sehnert, MD; Sucheta Bhatt, MD; Kathryn Murray, MS; Tracy L. Prosen, MD; Judy E. Garber, MD; Louise Wilkins-Haug, MD, PhD; Neeta L. Vora, MD; Stephen Warsof, MD; James Goldberg, MD; Tina Ziainia, MD; Meredith Halks-Miller, MD JAMA. 2015;314(2):162-169. doi:10.1001/jama.2015.7120 Importance: Understanding the relationship between aneuploidy detection on...

Duration: 00:04:29