Intelligent Medicine

Nutritionist Leyla Muedin focuses on a new perspective in Alzheimer's research, particularly the role of microglial cells. She reveals insights from integrative neurologist Dr. David Perlmutter's presentation at the Integrative Healthcare Symposium, emphasizing the significance of microglial cells in Alzheimer's disease. The discussion highlights the traditional focus on beta amyloid plaques and introduces the importance of shifting from the M1 pro-inflammatory phenotype to the M2 anti-inflammatory phenotype of microglial cells. Dr. Perlmutter advocates for addressing systemic metabolic and inflammatory issues, pointing out factors like poor diet, lack of sleep, and high blood sugar, which are crucial in preventing Alzheimer's. The episode delves into lifestyle interventions such as ketogenic diets, fasting, and nutritional impacts to manage and potentially reverse the detrimental shift in microglial behavior.

Clinical Pharmacist, Author, Board-Certified Clinical Nutritionist, and Health Expert Jim LaValle details the many health benefits of aged garlic extract, particularly its impact on periodontal disease. He reveals exciting new research findings that show Kyolic Aged Garlic Extract supplements can significantly reduce periodontal pocket depth -- a key indicator of gingivitis and periodontal disease progression. He also highlights the role of aged garlic extract in reducing inflammation and improving gum health, which in turn has significant implications for cardiovascular and cognitive health. The conversation also touches on various formulations of aged garlic extract available from Kyolic, the importance of integrative approaches to health and wellness, and updates on the latest trends in anti-aging medicine, including peptides and GLP-1 agonists.

Dr. Hoffman continues his conversation with clinical pharmacist, author, board-certified clinical nutritionist, and health expert Jim LaValle on the many health benefits of aged garlic extract.

Nathan Jones, CEO of Xlear, Inc., details the benefits of xylitol in dental and respiratory health products such as nasal sprays and chewing gums under the Spry brand. Nathan advocates for the FDA to allow anti-cavity claims for xylitol and other compounds despite the current monopoly of fluoride in such claims. They question the efficacy and potential downsides of fluoride, and explore alternative dental health interventions. The episode also covers xylitol’s role in preventing tooth decay, respiratory health benefits during the COVID-19 pandemic, and ongoing legal challenges with the FTC. Discussions highlight the potential implications of oral health on systemic diseases like cardiovascular disease and Parkinson’s, and emphasize the importance of nasal hygiene alongside dental care.

Dr. Hoffman continues his conversation with Nathan Jones, CEO of Xlear, Inc.

“Study” that’s not even a study spreads panic about dubious melatonin-heart failure link; Should you ignore dr’s advice to take powerful acid-blocking drugs? Novel implantable electrical pacemakers may bring relief to sufferers of severe constipation; Benefits of cocoa flavanols for heart, brain, athletic performance. Give the gift of healthy chocolate! Go to FlavaNaturals.com and use coupon code HOFFMAN20 for 20% off site-wide. Plus get free shipping on all orders over $30.

The FDA belatedly liberates women’s hormone replacement; Beta-blockers now deemed passé for routine heart attack aftercare; After most breast cancer surgery, adjuvant radiation brings no survival benefits; Can you drink caffeinated coffee if you have atrial fibrillation? Ignore frequent falls without attention to balance and stability training at your peril; Is it reasonable to contemplate a knee replacement surgery at 88?

Navigating the Complexities of Antinutrients in Your Diet: Leyla Muedin, a registered dietitian nutritionist, delves into the controversial topic of antinutrients. Responding to a question from a listener named Deanna, Leyla explains the different types of antinutrients—such as phytates, oxalates, tannins, lectins, goitrogens, and phytoestrogens—and their potential impacts on nutrient absorption. She discusses the dual nature of these compounds, highlighting their possible negative effects along with their roles in health benefits like gut microbiota support and anti-cancer properties. Leyla also shares practical food preparation tips for mitigating the adverse effects of antinutrients and emphasizes the importance of dietary variety.

Fertility specialist Gabriela Rosa, the CEO and founder of the Rosa Institute, discusses the decline in fertility rates, the experiences of couples struggling to conceive, and the multifaceted methods used to address this issue. Gabriela shares her journey of merging conventional and holistic fertility sciences, citing real-life cases of couples who succeeded in conceiving after addressing underlying health issues. They delve into the importance of lifestyle factors, such as diet, exercise, and mental health, and discuss specific interventions like hormone management and supplements. The conversation also covers environmental influences, the role of metabolic health, and the critical importance of personalized treatment plans for couples facing infertility. Gabriela provides insights on how to balance high-tech and holistic approaches to optimize fertility outcomes.

Dr. Hoffman continues his conversation with fertility specialist Gabriela Rosa, the CEO and founder of the Rosa Institute.

Neil Levin, Senior Nutrition Education Manager and product formulator for Now Foods and Protocol for Life Balance, discusses the importance of targeted nutrients for women's health. They delve into various supplements such as magnesium, myo-inositol, progesterone cream, D-Mannose, and biotin, explaining their benefits for conditions like PCOS, blood sugar regulation, menstrual migraines, urinary tract infections, and overall skin, hair, and nail health. The conversation also touches on the importance of tailoring nutrients to individual needs and the role of personalized nutrition in supporting women's health amidst modern stresses.

Dr. Hoffman continues his conversation with Neil Levin, Senior Nutrition Education Manager and product formulator for Now Foods and Protocol for Life Balance.

Just 4 simple lifestyle measures deliver 9 additional years of disease-free healthspan; Study underscores protein’s role in staving off cancer, heart disease, and death; CoQ10 scores vs. neurodegeneration; Urolithin A (Mitopure®️) found to support athletic performance, immune function; Why you should ignore some influencers’ advice to avoid fish oil.

As little as 3000 steps per day can slow progression to Alzheimer’s Disease; Self-reports of memory impairment soaring among young people; New study vindicates unprocessed red meat—and even often-vilified processed red meat—for cancer and overall health. Prostate artery embolization (PAE) offers new non-invasive option for men’s age-related urinary problems; Targeting the mitochondria and the microbiome for Parkinson’s Disease; Popular prostate and hair loss prevention drugs linked to depression and suicide—while Cialis for urinary symptoms may stave off cardiovascular disease; Discovery that a safe, cheap medication may increase survival after breast cancer surgery.

Nutritionist Leyla Muedin discusses the differences between gluten intolerance and fructan intolerance, highlighting how many people mistakenly attribute their symptoms to gluten. She explains the role of FODMAPs in diet, their impact on gut health, and the importance of a personalized approach to managing intolerances. Additionally, Leyla reviews a recent study showing that vegans have significantly lower levels of Omega-3 fatty acids compared to other dietary groups, emphasizing the need for careful planning and necessary supplementation to maintain optimal health for those on plant-based diets.