Nature Podcast

00:45 A squid-inspired device for needle-free drug delivery Inspired by squids’ ability to shoot ink, a team of researchers have developed swallowable devices that can deliver tiny jets of drugs directly into the gut lining, circumventing the need for needles. Previous studies have shown that most people prefer to take medication in pill form, rather than as an injection, but many drugs are degraded as they pass through the digestive system. The team’s new swallowable devices overcome this issue, and deliver drugs directly to where they need to be. So far, this approach has shown efficacy in animal models, but more work needs to be done to ensure their safety in humans. Research Article: Arrick et al. 10:50 Research Highlights The largest ‘terror bird’ fossil ever found, and a simple solution to help prevent premature births. Research Highlight: Huge carnivorous ‘terror bird’ rivalled the giant panda in size Research Highlight: Reducing pregnancy risk could be as easy as chewing gum 12:52 A milder way to break down ‘forever chemicals’. Two papers describe how light-activated catalysts could be used to break down toxic ‘forever chemicals’, hinting at a new way to clean up pollution caused by these persistent compounds. Forever chemicals contain multiple carbon-fluorine bonds that give them useful physical properties, but these bonds are some of the strongest in organic chemistry, making these compounds energetically difficult to break down. The new, light-based methods demonstrate low-energy ways to sever these bonds, a milestone that could make forever chemicals less permanent. Research Article: Zhang et al. Research Article: Liu et al. News and Views: Catalysts degrade forever chemicals with visible light 21:04 Briefing Chat Analysis of far-side soil highlights the Moon’s turbulent past, and how CRISPR can help make sweeter tomatoes. Nature: First rocks returned from Moon’s far side reveal ancient volcanic activity CNN: Findings from the first lunar far side samples raise new questions about the moon’s history Nature: CRISPR builds a big tomato that’s actually sweet Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. Hosted on Acast. See acast.com/privacy for more information.

00:46 The role of skull bone marrow in ageing During ageing, bone marrow in the skull becomes an increasingly important site of blood-cell production. This is in stark contrast to most bones where the ability of marrow to make blood and immune cells declines. Studies in mice and humans showed that ageing results in skull bone-marrow expanding, and in mice this marrow was more resistant to inflammation and other hallmarks of ageing. The team behind the work hope by understanding this process better it may be possible to help organs become more resistant to ageing. Research Article: Koh et al. 08:56 Research Highlights Elderly big brown bats show remarkable resistance to age-related hearing loss, and why search-engine algorithms may not be the main driver steering people towards misinformation. Research Highlight: No hearing aids needed: bats’ ears stay keen well into old age Research Highlight: Don’t blame search engines for sending users to unreliable sites 11:38 How to make lead a useful material to date the Solar System Researchers have overcome a major hurdle preventing the radioactive isotope lead-205 from being used as a ‘clock’ to date the age of the Solar System. 205Pb is made in some stars and thanks to its half life of around 17 million years has been proposed as a potential way to date ancient astronomical processes. However, exactly how much 205Pb can escape a star were unclear, limiting its dating potential. Now, researchers have mimicked the conditions seen in stars to pin down how much 205Pb can escape into space, paving the way for its use as a clock. Research Article: Leckenby et al. 19:51 Briefing Chat How millions of Android smartphones were used to map the Earth’s ionosphere, and the ethical implications of a virologist who treated her own cancer. Nature: Google uses millions of smartphones to map the ionosphere Nature: This scientist treated her own cancer with viruses she grew in the lab Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. Hosted on Acast. See acast.com/privacy for more information.

Samantha Harvey's Booker Prize shortlisted novel Orbital is set inside an International Space Station-like vessel circling 250 miles above Earth. It looks at a day-in-the-life of the crew, investigating the contrasts they experience during the 16 orbits they make around the planet, crossing continents, oceans and the line separating night and day. On the latest episode of Nature hits the books, Samantha joins us to discuss why the ISS is a rich setting for fiction, the challenges of putting yourself in the shoes of an astronaut, and how distance can give new perspectives on global issues like climate change. Orbital Samantha Harvey Vintage (2024) Music supplied by Airae/Epidemic Sound Hosted on Acast. See acast.com/privacy for more information.

00:46 Mitochondria divide their labour to help cells thrive Researchers have uncovered that mitochondria divide into two distinct forms when cells are starved, a finding that could help explain how some cancers thrive in hostile conditions. Mitochondria are cellular powerhouses, creating energy and vital metabolic molecules, but how they are able to do this when resources are limited has been a mystery. It turns out that in nutrient-poor situations, mitochondria split into two separate types, one which concentrates on energy production, the other on producing essential cellular building blocks. Together these allow cells to make everything they need. The team showed that this also happens in certain cancer cells, which may help them survive and grow under hostile conditions in the body. Research Article: Ryu et al. News and Views: Division of labour: mitochondria split to meet energy demands Video: A new kind of mitochondrion 07:53 Research Highlights A tidy genome may explain naked mole rats’ long lifespans, and why the midlife crisis may not be as ubiquitous as previously thought. Research Highlight: Naked mole rats vanquish genetic ghosts — and achieve long life Research Highlight: The midlife crisis is not universal 10:41 A smashing way to snapshot an atomic nuclei’s shape Physicists have revealed a new technique to image the shape of atomic nuclei — by smashing them together. The nucleus of an atom doesn’t really resemble what is shown in textbooks — they actually come in a variety of shapes, which drive an element’s behaviour. Current methods essentially take a long-exposure photo of an atom’s nucleus, which doesn’t capture the subtle variations in how the protons and neutrons arrange themselves. The new method overcomes this by colliding nuclei together and then using information on the resulting debris to reconstruct the shape of the nucleus. The researchers hope that this technique can help physicists resolve many more mysteries about atomic nuclei. Research Article: STAR Collaboration News: Scientists worked out the shapes of atomic nuclei — by exploding them 19:51 Briefing Chat Analysing the genome of an ancient clone forest has revealed it could be up to 80,000 years old, and how putting limits on the famous infinite monkey theorem means they probably wouldn’t churn out Shakespeare before the end of the Universe. Nature: The world’s oldest tree? Genetic analysis traces evolution of iconic Pando forest The Guardian: Universe would die before monkey with keyboard writes Shakespeare, study finds Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. Hosted on Acast. See acast.com/privacy for more information.

This series was originally broadcast in 2020. Science and politics are not easy bedfellows - "Stick to the science" is a three part series which aims to find out why. In the third and final episode we try to get to the bottom of how journalists, communicators and policymakers influence how science is perceived. We discuss the danger of politicization and ask the question - can science be part of the political narrative without compromising its values? This episode was produced by Nick Petrić Howe, with editing from Noah Baker and Benjamin Thompson. It featured: Deborah Blum, Bruce Lewenstein, Dan Sarewitz, Hannah Schmid-Petri, Shobita Parthasarathy, and Beth Simone Noveck. Further Reading The great fish pain debate Politicization of mask wearing Masks work Donald Trump used a quote from Anthony Fauci to falsely suggest Fauci approved of his actions in the pandemic Comparing Norway and Sweden in their coronavirus combating actions Beth Simone Noveck argues for more open and transparent governance Solving Public Problems, by Beth Simone Noveck Smart Citizens, Smarter State: The Technologies of Expertise and the Future of Governing, by Beth Simone Noveck The Received Wisdom Podcast, with Shobita Parthasarathy Hosted on Acast. See acast.com/privacy for more information.

This series was originally broadcast in 2020. Science and politics are not easy bedfellows - "Stick to the science" is a three part series which aims to find out why. In this episode we're asking how politics shapes the life of a working scientist. Be it through funding agendas, cultural lobbies or personal bias, there's a myriad of ways in which politics can shape the game; influencing the direction and quality of research, But what does this mean for the objective ideals of science? This episode was produced by Nick Petrić Howe, with editing from Noah Baker and Benjamin Thompson. it featured contributions from many people, including: Mayana Zatz, Shobita Parthasarathy, Michael Erard, Peg AtKisson, Susannah Gal, Allen Rostron, Mark Rosenberg, and Alice Bell. Further Reading Brazil’s budget cuts threaten more than 80,000 science scholarships Move to reallocate funds from scientific institutions in São Paulo Backlash to “Shrimps on a treadmill” Explanation of the Dickey Amendment After over 20 years the CDC can now fund gun violence research Spirometer use “race-correction” software Black researchers less likely to get funding from the National Institutes of Health in the US Black researchers may get less funding from the National Institutes of Health due to topic choice Black researchers fill fewer academic roles in the UK Clinical trials use mostly white participants The Received Wisdom Podcast, with Shobita Parthasarathy Hosted on Acast. See acast.com/privacy for more information.

This series was originally broadcast in 2020. Science and politics are not easy bedfellows - "Stick to the science" is a three part series which aims to find out why. In this episode we delve into the past, and uncover the complicated relationship between science, politics and power. Along the way, we come up against some pretty big questions: what is science? Should science be apolitical? And where does Nature fit in? This episode was produced by Nick Petrić Howe, with editing from Noah Baker and Benjamin Thompson. it featured contributions from many researchers, including: Shobita Parthasarathy, Alice Bell, Dan Sarewitz, Anna Jay, Melinda Baldwin, Magdelena Skipper, Steven Shapin, David Edgerton, Deborah Blum, Bruce Lewenstein and Chiara Ambrosio. Quotes from social media were read by: Shamini Bundell, Flora Graham, Dan Fox, Edie Edmundson and Bredan Maher. And excerpts from Nature were read by Jen Musgreave. Further Reading History of Education in the UK Nature’s History Nature’s Mission statement Nature editorial on covering politics Making “Nature”, by Melinda Baldwin Never Pure: Historical Studies of Science as if It Was Produced by People with Bodies, Situated in Time, Space, Culture, and Society, and Struggling for Credibility and Authority, by Steven Shapin David Edgerton’s writing on the history of science and politics in the Guardian The received wisdom podcast with Shobita Parthasarathy Hosted on Acast. See acast.com/privacy for more information.

00:48 Rebuilding mental health after the floods Researchers have been investigating the best ways to help people deal with trauma in the wake of a climate disaster. In April and May devastating floods surged across Rio Grande do Sul in the South of Brazil, affecting two million people and killing hundreds. As people try to put their lives back together scientists have been conducting surveys and investigating how to make sure that any mental health issues don’t become persistent. We hear from some of the affected people and researchers in the region. This story was supported by the Pulitzer Center. News Feature: How to recover when a climate disaster destroys your city 13:48 Research Highlights A new way to make ultra-heavy elements, and how some plankton swim by blowing up like a balloon. Research Highlight: Atomic smash-ups hold promise of record-breaking elements Research Highlight: This plankton balloons in size to soar upwards through the water 16:54 What are your thoughts on the US election? Nature has conducted a poll of its readers to get a sense of what is on researchers’ minds in the run up to the US election. Overwhelmingly, the survey respondents identified as researchers and reported that they supported Vice President Harris (86%). Many also voiced concerns about a possible victory for former President Trump, saying that they would consider changing where they would live if he wins. Reporter Jeff Tollefson tells us more about the results and what the election means for US science. News: The US election is monumental for science, say Nature readers — here’s why 27:07 Briefing Chat The possible benefits of ‘poo milkshakes’ for newborns, and how Tardigrades can withstand incredibly high levels of radiation. Nature: ‘Poo milkshake’ boosts the microbiome of c-section babies Nature: New species of tardigrade reveals secrets of radiation-resisting powers Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. Hosted on Acast. See acast.com/privacy for more information.

By the end of 2024 up to two billion people will have gone to the polls, in a pivotal year of elections around the globe. This is giving political scientists the chance to dive into each election in detail but also to compare the differing voting systems involved. They hope understanding the advantages and drawbacks of the systems will help highlight whether some are more likely to promote democratic resilience or to stave off corrosive partisanship. This is an audio version of our Feature: Which is the fairest electoral system? Mega-election year sparks debate Hosted on Acast. See acast.com/privacy for more information.

00:48 The hidden cities of Uzbekistan Researchers have uncovered the scale of two ancient cities buried high in the mountains of Uzbekistan. The cities were thought to be there, but their extent was unknown, so the team used drone-mounted LiDAR equipment to reveal what was hidden beneath the ground. The survey surprised researchers by showing one of the cities was six times bigger than expected. The two cities, called Tashbulak and Tugunbulak, were nestled in the heart of Central Asia’s medieval Silk Road, suggesting that highland areas played an important role in trade of the era. Research Article: Frachetti et al. Video: Uncovering a lost mountain metropolis 09:32 Research Highlights How children's’ movements resemble water vapour, and why coastal waters may be a lot dirtier than we thought. Research Highlight: Kids in the classroom flow like water vapour Research Highlight: Sewage lurks in coastal waters — often unnoticed by widely used test 12:06 Watermarking AI-generated text A team at Google Deepmind has demonstrated a way to add a digital watermark to AI-generated text that can be detected by computers. As AI-generated content becomes more pervasive, there are fears that it will be impossible to tell it apart from content made by humans. To tackle this, the new method subtly biases the word choices made by a Large Language Model in a statistically detectable pattern. Despite the changes to word choice, a test of 20 million live chat interactions revealed that users did not notice a drop in quality compared to unwatermarked text. Research Article: Dathathri et al. News: DeepMind deploys invisible ‘watermark’ on AI-written text 22:38 Briefing Chat What one researcher found after repeatedly scanning her own brain to see how it responded to birth-control pills, and how high-altitude tree planting could offer refuge to an imperilled butterfly species. Nature: How does the brain react to birth control? A researcher scanned herself 75 times to find out Nature: Mexican forest ‘relocated’ in attempt to save iconic monarch butterflies Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. Hosted on Acast. See acast.com/privacy for more information.

In this episode: 00:46 An unusual γ-ray producing microquasar A type of binary-system known as a microquasar has been found to be firing out γ-rays at high energy-levels, which may make it a candidate to be a long-theorized natural particle-accelerator known as a PeVatron. These objects are thought to be a source of galactic cosmic rays, the origins of which are currently a mystery. Understanding how this microquasar works could also help researchers learn more about full-sized quasars — monstrous objects centred around supermassive black holes, which are too distant to study easily. Research Article: Alfaro et al. News and Views: High-altitude particle detector spots a second Galactic microquasar 09:27 Research Highlights The comb jellies caught fusing their bodies, and an ancient burial site reveals that Classical accounts of Scythian culture appear to be true. Research Highlight: Two comb jellies fuse their bodies and then act as one Research Highlight: Evidence of dead people posed on dead horses found in ancient tomb 12:08 A ‘smart’ insulin-molecule that could lower hypoglycaemia risk Researchers have developed a modified insulin-molecule that varies its level of activity depending on blood-glucose levels. It’s hoped that this ‘smart’ insulin could one day help those with diabetes regulate their blood sugar more easily. Many people with diabetes rely on regular insulin injections, but because blood-sugar levels can be difficult to predict it can be hard to select the correct dose. This can lead to hypoglycaemia — a life-threateningly low level of glucose. To overcome this, a team created a modified form of insulin with a switch that activates the molecule when glucose levels are high, and deactivates it when levels are low. This insulin-molecule was effective at maintaining correct blood glucose in animal models, and may eventually help lessen diabetes-related complications in humans. Research Article: Hoeg-Jensen et al. News and Views: Smart insulin switches itself off in response to low blood sugar 20:33 Briefing Chat Ancient DNA confirms that infamous lions hunted humans and a variety of game, and a new technique can sequence a cell’s DNA and pinpoint its proteins, without cracking it open. Nature: Famed lions’ full diet revealed by DNA — and humans were among their prey Nature: ‘Phenomenal’ tool sequences DNA and tracks proteins — without cracking cells open Hosted on Acast. See acast.com/privacy for more information.

00:55 Graphene Tongue Researchers have developed a graphene ‘tongue’ that uses AI to tell the subtle differences between drinks. Graphene has long been sought after as a chemical sensor, but tiny variations between devices have meant that it couldn’t be used very reliably. The team behind the ‘tongue’ got around this problem by training an AI to tell the difference between similar liquids regardless of variations between graphene devices. They hope that their work shows that it’s possible to use ‘imperfect’ chemical sensors to get accurate readings and that the ‘tongue’ will be able to help detect problems with food. Research Article: Pannone et al. 09:22 Research Highlights A 3D-printed optical microscope that can image biological samples with ultrahigh resolution, and how newly-hatched sea turtles dig their way up to the beach. Research Highlight: A ‘Swiss army knife’ microscope that doesn’t break the bank Research Highlight: Baby sea turtles ‘swim’ up from buried nests to the open air 11:32 How migrating salmon move nutrients and contaminants at a continental scale Studies of migrating Pacific salmon have revealed that these animals transport thousands of tonnes of nutrients and kilograms of contaminants from the ocean to freshwater ecosystems. It’s been known that as the fish return to their freshwater spawning grounds from the sea they bring with them both nutrients and contaminants, but the impact of each has largely been studied separately. A new study combines datasets to estimate that over 40 years, the levels of nutrients these fish carry have increased at a proportionally higher rate than the contaminants, but the toxins could nevertheless be present at concerning levels to the animals that eat them. Research Article: Brandt et al. News and Views: Salmon’s moveable feast of nutrients with a side order of contaminants 23:19 Nobel News Flora Graham from the Nature Briefing joins us to talk about the winners of this year’s science Nobel Prizes. News: Medicine Nobel awarded for gene-regulating ‘microRNAs’ News: Physics Nobel scooped by machine-learning pioneers News: Chemistry Nobel goes to developers of AlphaFold AI that predicts protein structures Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. Hosted on Acast. See acast.com/privacy for more information.

00:46 Physicists spot new types of high-energy radiation in thunderstorms Physicists have identified new forms of γ-ray radiation created inside thunderclouds, and shown that levels of γ-ray production are much higher on Earth than previously thought. Scientists already knew about two types of γ-ray phenomena in thunderclouds — glows that last as long as a minute and high-intensity flashes that come and go in only a few millionths of a second. Now, researchers have identified that these both occur more frequently than expected, and that previously undetected γ-ray types exist, including flickering flashes that share characteristics of the other two types of radiation. The researchers hope that understanding more about these mysterious phenomena could help explain what initiates lightning, which often follows these γ-ray events. Research Article: Østgaard et al. Research Article: Marisaldi et al. Nature: Mysterious form of high-energy radiation spotted in thunderstorms 10:00 Research Highlights Ancient arrowheads reveal that Europe's oldest battle likely featured warriors from far afield, and why the dwarf planet Ceres’s frozen ocean has deep impurities. Research Highlight: Bronze Age clash was Europe’s oldest known interregional battle Research Highlight: A dwarf planet has dirty depths, model suggests 12:09 A complete wiring diagram of the fruit fly brain Researchers have published the most complete wiring diagram, or ‘connectome’ of the fruit fly’s brain, which includes nearly 140,000 neurons and 54.5 million connections between nerve cells. The map, made from the brain of a single female fruit fly (Drosophila melanogaster), reveals over 8,400 neuron types in the brain, and has enabled scientists to learn more about the brain and how it controls aspects of fruit fly behaviour. The FlyWire connectome: neuronal wiring diagram of a complete fly brain Nature: Largest brain map ever reveals fruit fly's neurons in exquisite detail 22:16 Briefing Chat How researchers created an elusive single-electron bond between carbon atoms, and why bigger chatbots get over-confident when answering questions. Nature: Carbon bond that uses only one electron seen for first time: ‘It will be in the textbooks’ Nature: Bigger AI chatbots more inclined to spew nonsense — and people don't always realize Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. Hosted on Acast. See acast.com/privacy for more information.

The world's fastest supercomputer, known as Frontier, is located at the Leadership Computing Facility at Oak Ridge National Laboratory in Tennessee. This machine churns through data at record speed, outpacing 100,000 laptops working simultaneously. With nearly 50,000 processors, Frontier was designed to push the bounds of human knowledge. It's being used to create open-source large language models to compete with commercial AI systems, simulate proteins for drug development, help improve aeroplane engine design, and more. This is an audio version of our Feature: A day in the life of the world’s fastest supercomputer Hosted on Acast. See acast.com/privacy for more information.

In this episode: 00:46 Unravelling why children with Down’s syndrome are at a higher risk of leukaemia Children with Down’s syndrome have a 150-fold increased risk of developing leukaemia than those without the condition. Now, an in-depth investigation has revealed that changes to genome structures in fetal liver stem-cells appear to be playing a key role in this increase. Down’s syndrome is characterised by cells having an extra copy of chromosome 21. The team behind this work saw that in liver stem-cells — one of the main places blood is produced in a growing fetus — this extra copy results in changes in how DNA is packaged in a nucleus, opening up areas that are prone to mutation, including those known to be important in leukaemia development. The researchers hope their work will be an important step in understanding and reducing this risk in children with Down’s syndrome. Research Article: Marderstein et al. News and Views: Childhood leukaemia in Down’s syndrome primed by blood-cell bias 11:47 Research Highlights How taking pints of beer off the table lowers alcohol consumption, and a small lizard’s ‘scuba gear’ helps it stay submerged. Research Highlight: A small fix to cut beer intake: downsize the pint Research Highlight: This ‘scuba diving’ lizard has a self-made air supply 14:12 Briefing Chat How tiny crustaceans use ‘smell’ to find their home cave, and how atomic bomb X-rays could deflect an asteroid away from a deadly Earth impact. Science: In the dark ocean, these tiny creatures can smell their way home Nature: Scientists successfully ‘nuke asteroid’ — in a lab mock-up Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. Hosted on Acast. See acast.com/privacy for more information.

In this episode: 00:45 The biggest black hole jets ever seen Astronomers have spotted a pair of enormous jets emanating from a supermassive black hole with a combined length of 23 million light years — the biggest ever discovered. Jets are formed when matter is ionized and flung out of a black hole, creating enormous and powerful structures in space. Thought to be unstable, physicists had theorized there was a limit to how large these jets could be, but the new discovery far exceeds this, suggesting there may be more of these monstrous jets yet to be discovered. Research Article: Oei et al. 09:44 Research Highlights The knitted fabrics designed to protect wearers from mosquito bites, and the role that islands play in fostering language diversity. Research Highlight: Plagued by mosquitoes? Try some bite-blocking fabrics Research Highlight: Islands are rich with languages spoken nowhere else 12:26 A sustainable, one-step method for alloy production Making metal alloys is typically a multi-step process that creates huge amounts of emissions. Now, a team demonstrates a way to create these materials in a single step, which they hope could significantly reduce the environmental burdens associated with their production. In a lab demonstration, they use their technique to create an alloy of nickel and iron called invar — a widely-used material that has a high carbon-footprint. The team show evidence that their method can produce invar to a quality that rivals that of conventional manufacturing, and suggest their technique is scalable to create alloys at an industrial scale. Research article: Wei et al. 25:29 Briefing Chat How AI-predicted protein structures have helped chart the evolution of a group of viruses, and the neurons that cause monkeys to ‘choke’ under pressure. Nature News: Where did viruses come from? AlphaFold and other AIs are finding answers Nature News: Why do we crumble under pressure? Science has the answer Subscribe to the Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. Hosted on Acast. See acast.com/privacy for more information.

In this episode: 00:45 What ancient DNA has revealed about Rapa Nui’s past Ancient DNA analysis has further demonstrated that the people of Rapa Nui did not cause their own population collapse, further refuting a controversial but popular claim. Rapa Nui, also known as Easter island, is famous for its giant Moai statues and the contested idea that the people mismanaged their natural resources leading to ‘ecological suicide’. Genomes sequenced from the remains of 15 ancient islanders showed no evidence of a sudden population crash, substantiating other research challenging the collapse idea. Research Article: Moreno-Mayar et al. News and Views: Rapa Nui’s population history rewritten using ancient DNA News article: Famed Pacific island’s population 'crash' debunked by ancient DNA 17:03 Research Highlights The extinct bat-eating fish that bit off more than they could chew, and how manatee dung shapes an Amazonian ecosystem. Research Highlight: Ancient fish dined on bats — or died trying Research Highlight: The Amazon’s gargantuan gardeners: manatees 19:29 A macabre parasite of adult fruit flies Despite being a hugely-studied model organism, it seems that there’s still more to find out about the fruit fly Drosophila melanogaster, as researchers have discovered a new species of parasitoid wasp that infects the species. Unlike other parasitic wasps, this one lays its eggs in adult flies, with the developing larva devouring its host from the inside. The miniscule wasp was discovered by chance in an infected fruit fly collected in a Mississippi backyard and analysis suggests that despite having never been previously identified, it is widespread across parts of North America. Research article: Moore et al. 32:04 Briefing Chat How a dye that helps to give Doritos their orange hue can turn mouse tissues transparent, and an effective way to engage with climate-science sceptics. Nature News: Transparent mice made with light-absorbing dye reveal organs at work Nature News: How to change people’s minds about climate change: what the science says Hosted on Acast. See acast.com/privacy for more information.

The often repeated claim that "80% of the world's biodiversity is found in the territories of Indigenous Peoples" appears widely in policy documents and reports, yet appears to have sprung out of nowhere. According to a group of researchers, including those from Indigenous groups, this baseless statistic could be undermining the conservation efforts of the Indigenous People it's meant to support and prevent further work to really understand how best to conserve biodiversity. Two of the authors joined us to discuss how this statistic gained traction, the harm it could cause, and how better to support the work of Indigenous Peoples. Read more in a Comment article from the authors: No basis for claim that 80% of biodiversity is found in Indigenous territories Hosted on Acast. See acast.com/privacy for more information.

In this episode: 00:45 Why a 'nuclear clock' is now within researchers’ reach Researchers have made a big step towards the creation of the long theorized nuclear clock, by getting the most accurate measurement of the frequency of light required to push thorium nuclei into a higher energy state. Such a timekeeper would differ from the best current clocks as their ‘tick’ corresponds to the energy transitions of protons and neutrons, rather than electrons. Nuclear clocks have the potential to be more robust and accurate than current systems, and could offer researchers new insights into fundamental forces present within atomic nuclei. Research Article: Zhang et al. News and Views: Countdown to a nuclear clock Nature News: ‘Nuclear clock’ breakthrough paves the way for super-precise timekeeping Editorial: Progress on nuclear clocks shows the benefits of escaping from scientific silos 10:10 Research Highlights The star that got partially shredded by a supermassive black hole, not just once, but twice, and how heatwaves could mangle bumblebees’ sense of smell. Research Highlight: This unlucky star got mangled by a black hole — twice Research Highlight: Bumblebees’ sense of smell can’t take the heat 12:11 How engineered immune cells could help limit damage after spinal injury By harnessing T cells to fine-tune the inflammation response, researchers have limited the damage caused by spinal injury in mice, an approach they hope might one day translate into a human therapy. Following injury to the central nervous system, immune cells rush to the scene, resulting in a complex array of effects, both good and bad. In this work researchers have identified the specific kind of T cells that amass at the site, and used them to create an immunotherapy that helps the mice recover more quickly from injuries by slowing damage to neurons. Research article: Gao et al. 20:36 Briefing Chat How unprecedented floods in Brazil have helped and hindered paleontologists, and the ‘AI scientist’ that does everything from literature review through to manuscript writing, to an extent. Nature News: The race to save fossils exposed by Brazil’s record-setting floods Nature News: Researchers built an ‘AI Scientist’ — what can it do? Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. Hosted on Acast. See acast.com/privacy for more information.

The 'file-drawer problem', where findings with null or negative results gather dust and are left unpublished, is well known in science. There has been an overriding perception that studies with positive or significant findings are more important, but this bias can have real-world implications, skewing perceptions of drug efficacies, for example. Multiple efforts to get negative results published have been put forward or attempted, with some researchers saying that the incentive structures in academia, and the ‘publish or perish’ culture, need to be overturned in order to end this bias. This is an audio version of our Feature: So you got a null result. Will anyone publish it? Hosted on Acast. See acast.com/privacy for more information.