
Could Be Worse, a Toxicology Podcast
Medical
A toxicology podcast designed to give a quick overview of different chemicals starting with ones causing much of the morbidity and mortality as reported to poison control centers. It also covers what can be learned from these exposures.
Location:
United States
Description:
A toxicology podcast designed to give a quick overview of different chemicals starting with ones causing much of the morbidity and mortality as reported to poison control centers. It also covers what can be learned from these exposures.
Language:
English
Website:
https://anchor.fm/ed7881
Episodes
US FDA Guidance on Disproportionate Metabolites
4/17/2025
Abridged version of the US FDA Guidance on Disproportionate Metabolites. The full version of the guidance can hopefully still be found at www.fda.gov. This is one of the references for the ABT exam. Disclaimer: I am not a member of the board and this did not involve the board.
Duration:00:15:45
OECD 207 Earthworm Acute Toxicity Tests
3/25/2025
Abridged version of OECD 207 Earthworm Acute Toxicity Tests.
Duration:00:09:45
OECD 202 Daphnia Immobilization
3/10/2025
Abridged version of OECD 202 Daphnia Immobilization Assay
Duration:00:12:29
The in silico reference question.
8/29/2023
This episode covers four kinds of in silico methods identifying the one that can be used to leverage the toxicological data from one chemical for a similar chemical lacking such data.
Duration:00:03:46
The Opioids and Cholinergics Antidotes Question
8/21/2023
This episode goes over the recently posted question about opioids, cholinergics, the antidotes used to treat them and what conditions associated with their respective toxidromes most need treatment with an antidote.
Duration:00:02:59
Theophylline question
8/14/2023
This episode covers a question a case that happened years ago where a group of children suddenly became agitated due to high blood theophylline levels.
Duration:00:03:08
Wasp Sting Question
7/1/2023
This episode explains the question posted on LinkedIn about a wasp sting that had an unusual reaction. The episode goes into the clues in wording of the question and how to eliminate the three other different routes of administration. It also explains where this strange but true sting took place.
Duration:00:04:48
2020 Hydrogen sulfide
3/16/2023
US Poison control center annual report case of hydrogen sulfide is covered.
Duration:00:04:38
DABT 2022 OECD 203 Acute Fish Toxicity
2/19/2023
This is an abridged version of the OECD 203 Acute Fish Toxicity Testing Guideline. Not every part or paragraph is covered as it is designed to highlight those parts most likely to be on the 2022 DABT Exam. For the actual practice of Toxicology please read the "Fine Manual."
Duration:00:24:03
DABT 2022 OECD 404 Acute Dermal Irritation/Corrosion
2/19/2023
Note this is ab abridged version of the guideline that highlights the information most likely to be on the DABT Exam. The actual guidance document contains more detail but since it's unlikely the DABT Exam will ask how many lumens should be provided when the lights are on that kind of detail has been omitted from this episode. For the actual practice of Toxicology please read the "Fine Manual" and the other associated guidance documents.
Duration:00:11:35
DABT 2022 ICH S1A Guideline on the Need for Carcinogenicity Studies for Pharmaceuticals
2/19/2023
This is an abridged version of the guideline that is focused on the parts of the guideline most likely to be covered on the DABT 2022 exam. As always for the actual practice of Toxicology, please read the "fine manual."
Duration:00:08:14
Episode 10 DABT 2022 ICH S1B
2/19/2023
This is an abridged version of the guideline focused on the parts most likely to be on the 2022 DABT exam. Some parts and paragraphs have been left out. As always for the actual practice of Toxicology please read the "fine manual."
Duration:00:09:51
DABT 2022 ICH S1C(R2) Carcinogenicity Testing Dosing
2/19/2023
This is an abridged version of the guideline focused on the parts most likely to be on the DABT exam. As always in the actual practice of Toxicology please read the "fine manual."
Duration:00:13:36
DABT 2022 ICH S2(R1) Guidance on Genotoxicity Testing and Data Interpretation for Pharmaceuticals
2/19/2023
This is an abridged version of the guideline focused primarily on the parts most likely to be on the DABT exam. There are additional ICH, OECD and other guidance documents referenced in this guideline. As always for the actual practice of Toxicology, please read the "fine manual."
Duration:00:42:29
Could Be Worse DABT 2022 ICH 3A Toxicokinetics
2/19/2023
This is an abridged version of the guidance focusing primarily on the parts most likely to be on the DABT exam. Some parts and even some paragraphs have been left out. There are additional notes and documents referenced that have been left out. As always for the actual practice of Toxicology, please read the "fine manual."
Duration:00:19:03
Could Be Worse DABT 2022 ICH S3B Pharmacokinetics
2/19/2023
This is an abridged version of the guideline focusing primarily on the parts most likely to be on the DABT exam. Some parts and even some paragraphs have been left out. There are also additional notes and references that have been left out. As always for the actual practice of Toxicology, please read the "fine manual."
Duration:00:03:26
Could Be Worse DABT 2022 ICH S4 Duration of Chronic Toxicity Testing
2/19/2023
This an abridged version of the guideline focusing primarily on the parts most likely to be on on DABT exam. Some parts and even some paragraphs have been left out. There are also additional notes and guidance documents left out. As always for the actual practice of Toxicology, please read the "fine manual." Also rodents for six months and non-rodents for nine months sums it up.
Duration:00:01:07
Could Be Worse DABT 2022 ICH S5 (R3) Detection of Reproductive and Developmental Toxicity
2/19/2023
This is a highly abridged version of the guideline focusing primarily on the parts most likely to be on the exam. There are notes, references and a really important but probably not so much for the exam appendix that have been left out. As always for the actual practice of Toxicology please read the "fine manual." And note the corrected stages of reproduction are at the end of the episodes.
Duration:00:45:39
Could Be Worse DABT 2022 ICH S6 (R1) Preclinical Safety Evaluation of Biotechnology-Derived "Drugs"
2/19/2023
Note it's actually pharmaceuticals but that won't fit. This is an abridged version of the guidelines focusing primarily on the parts most likely to be on the DABT exam. Some parts and even some paragraphs have been left out. There are additional notes and guidance documents referenced in this guideline. As always for the actual practice of Toxicology, please read the "fine manual." Note this is part 1 of 2 as this guideline has an addendum that is complimentary to this guidance document. If there is a disagreement between the two then the addendum wins.
Duration:00:23:37
Could Be Worse DABT 2022 ICH S6 (R1) Preclinical...Biotechnology-Derived Pharmaceuticals Addendum
2/19/2023
This is an abridged version of the guideline focusing primarily on the parts most likely to be on the DABT exam. Some parts and even some paragraphs have been left out. There are also additional notes and guidance documents referenced in this guideline. As always for the actual practice of Toxicology please read the "fine manual." Note this is part 2 of 2 as this guideline has an addendum that is complimentary to this guidance document. If there is a disagreement between the two then the addendum wins.
Duration:00:18:01