The ACR Interviews: Martin J. Blaser, MD
Martin J. Blaser, MD, is director of the Human Microbiome Program at NYU and author of the book, Missing Microbes. He sat down and spoke with us about how the microbiome plays a role in disease pathogenesis, including autoimmunity, and he also answered the question of whether all of our patients should be on probiotics! :11:351:201:251:492:133:124:205:216:437:549:0210:4512:2313:0913:5714:5415:3318:1819:4720:2620:33 We’d love to hear from you! Send your comments/questions to...
The History of Gout, Part 2
In this episode, explore data from the major study proving uric acid crystals are present in the synovial fluid of patients with gout, as well as the tale of two rheumatologists who injected their own knees (while still working in the hospital) with uric acid to prove it is the trigger for inflammation in gout. The episode finishes with some ripping yarns about the history of the medications we use to treat this...
The History of Gout, Part 1
Do you know the etymology of the word “gout,” or how a simple microscope aided in the identification of tophi? Join me as I explore the history of this inflammatory arthritis and highlight the important scientists who shaped the modern era of gout. :10:481:341:543:053:064:134:586:016:206:42The Lancet7:068:2911:3812:5713:4814:5815:3716:0916:2216:34 We’d love to hear from you! Send your comments/questions to firstname.lastname@example.org. References: Barnett R. Lancet....
A Bovine Conundrum
This episode discusses the case of an 85-year-old man with a history of hypertension and fairly recently diagnosed bladder cancer who presents with oligoarticular asymmetric inflammatory arthritis. Explore the details of this case and learn how bacillus Calmette-Guérin and reactive arthritis are related in this diagnostic conundrum. :10:18:32:531:212:062:242:533:033:244:254:546:186:457:187:4510:2810:5811:2914:3415:0716:1216:3117:0517:3218:1118:49 We’d love to hear from you! Send your...
TMI on TMA
This episode covers a rare but life-threatening complication of lupus nephritis called complement-mediated thrombotic microangiopathy. Rheumatologist Lisa Zickuhr, MD, helps us better understand this often-overwhelming topic with a clinical case example, treatment options and practice pearls. :10:441:502:153:103:353:505:359:1010:1013:0513:5015:4818:2318:5121:1222:3524:0525:1026:13 Lisa Zickuhr, MD, is a rheumatologist at Washington University in St. Louis. We’d love to hear from you! Send...
A Diagnosis Divided
A young woman presents with migraine-like headaches, black spots in her vision and emotional lability. Think you know the diagnosis? You may be surprised – this medical mystery is not what it seems. In this episode, learn more about this rare diagnosis, and gain clinical insight from neurologist Devon Conway, MD, and ophthalmologist Arthi Venkat,...
The History of Steroids
Do you know which U.S. president had Addison’s disease? Or how rumors from WWII led to funding for research on cortisol? In this episode, take a trip down memory lane as we detail the history of steroids and the scientists whose work lead to the discovery of prednisone. :14:401:182:103:396:157:138:4410:0310:1410:2511:1512:2314:2415:2117:0817:4318:34 We’d love to hear from you! Send your comments/questions to email@example.com. References: Benedek TG. Clin Exp Rheumatol....
A Look at Biosimilars
Biosimilars are a fascinating new category of medication and are quickly becoming part of the rheumatologist’s treatment armamentarium, but they can be confusing to understand. This episode will enhance your knowledge of this new class of medications by providing a better understanding of how biologics differ from most other medications, and why biosimilars aren’t just generics of biologics. This episode also takes a brief look into the history of drug regulation with a focus on biosimilars...
Giant Cell Arteritis with Leonard Calabrese, DO
Leonard Calabrese, DO, details the clinical manifestations of giant cell arteritis, the complex scenarios rheumatologists face when working with GCA, and the pathogenesis of this disease. Calabrese also shares clinical pearls and tips for success. :12:311:021:514:184:325:135:206:046:447:039:019:2511:3312:1913:1214:0014:2214:5815:0816:1016:3817:1817:4117:5418:17 Leonard Calabrese, DO, is head of Cleveland Clinic’s Section of Clinical Immunology, co-director of Center for Vasculitis Care and...
A Neck of Deception
What do a fever, stiff neck and leukocytosis have in common with a large swollen knee? Listen to this medical mystery to see if you can figure out the diagnosis, then stick around to hear interesting information you may not know about the disease, including historical perspectives. :10:372:122:243:033:334:305:086:046:246:547:539:3711:0512:4013:4014:2015:4416:1216:39 We’d love to hear from you! Send your comments/questions to firstname.lastname@example.org. References: Ali S, et al. J...