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The Journal of Immunology ImmunoCasts

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The Journal of Immunology ImmunoCasts

The Journal of Immunology ImmunoCasts
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Location:

United States

Description:

The Journal of Immunology ImmunoCasts

Language:

English


Episodes

[IMMUNOCAST] PILLARS OF IMMUNOLOGY

8/19/2019
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Dr. Katherine Fitzgerald discusses a 2002 paper by Jürg Tschopp and colleagues that first defined the formation of the inflammasome complex.

Duration:00:05:26

[IMMUNOCAST] PILLARS OF IMMUNOLOGY

6/17/2019
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Dr. Claudia Kemper discusses a 1985 PNAS paper that first identified CD46, a key regulatory molecule in the complement system.

Duration:00:11:34

[IMMUNOCAST] PILLARS OF IMMUNOLOGY

5/20/2019
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Dr. Todd Fehniger discusses two seminal papers that demonstrated a role for IL-15 in the development and survival of natural killer cells.

Duration:00:02:47

[IMMUNOCAST] PILLARS OF IMMUNOLOGY

2/19/2019
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Dr. Craig Bassing discusses a 1993 Science paper by Frederick Alt that demonstrating a role for RAG2 in T cell development.

Duration:00:03:40

[IMMUNOCAST] PILLARS OF IMMUNOLOGY

1/22/2019
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Dr. Shabaana Khader discusses a 2003 Nature paper by Daniel Cua that defined a specific role for IL-23 in autoimmune inflammation.

Duration:00:08:35

[IMMUNOCAST] PILLARS OF IMMUNOLOGY

12/26/2018
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Drs. Bethany Moore and Steven Kunkel discuss a 1987 PNAS paper that first identified a chemotactic cytokine that would eventually be known as IL-8.

Duration:00:06:47

[IMMUNOCAST] PILLARS OF IMMUNOLOGY

11/19/2018
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Dr. Dr. Mark Kaplan discusses a 1989 Science paper by Gerald Crabtree that demonstrated the mechanism by which cyclosporin A inhibited T cell activation.

Duration:00:03:42

[IMMUNOCAST] PILLARS OF IMMUNOLOGY

10/22/2018
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Dr. Uttiya Basu discusses a 1999 paper by the group of Tasuku Honjo that demonstrates a critical role for activation-induced cytidine deaminase in class switch recombination and somatic hypermutation of B cells.

Duration:00:05:44

[IMMUNOCAST] PILLARS OF IMMUNOLOGY

9/17/2018
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Dr. Luc van Kaer discusses a 1994 paper by the group of Dr. Don Wiley that demonstrated the binding of superantigens with the MHC class II molecule.

Duration:00:08:37

[IMMUNOCAST] PILLARS OF IMMUNOLOGY

8/20/2018
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Dr. Martin Flajnik discusses a 2004 Nature paper by Drs. Max Cooper and Zeev Pancer that identified the existence of variable lymphocyte receptors that which were generated by non-RAG-based rearrangement events.

Duration:00:12:12

[IMMUNOCAST] PILLARS OF IMMUNOLOGY

7/23/2018
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Dr. Wolf H. Fridman discusses a 2001 paper by the group of Robert Schreiber that established the foundations of modern immune-oncology.

Duration:00:06:05

[IMMUNOCAST] PILLARS OF IMMUNOLOGY

6/18/2018
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Dr. Philippa Marrack discusses a 1994 Nature paper by Charles Surh and Jonathan Sprent that identified apoptotic cells in the thymus during positive and negative selection.

Duration:00:04:05

[IMMUNOCAST] PILLARS OF IMMUNOLOGY

5/21/2018
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Dr. Dr. Jordan Orange discusses a 1994 Cell paper by Ute Francke that reported the discovery of the Wiskott Aldrich Syndrome Protein gene.

Duration:00:04:10

[IMMUNOCAST] PILLARS OF IMMUNOLOGY

4/23/2018
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Dr. Wendy Havran discusses a 2001 paper by Adrian Hayday that demonstrates anti-tumor functions for skin-resident gamma delta T cells.

Duration:00:05:24

[IMMUNOCAST] PILLARS OF IMMUNOLOGY

3/19/2018
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Dr. Eric Vivier discusses a 1999 paper by Thomas Spies that revealed a new mode of immune recognition via NKG2D on NK cells.

Duration:00:05:15

[IMMUNOCAST] PILLARS OF IMMUNOLOGY

2/20/2018
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Dr. Marc Peters-Golden discusses a 1978 paper by Robert Murphy and Bengt Samuelsson that provided the first structural characterization of leukotriene C4.

Duration:00:07:40

[IMMUNOCAST] PILLARS OF IMMUNOLOGY

1/22/2018
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Dr. Sebastian Amigorena discusses a 1994 paper by Sallusto and Lanzavecchia that made significant contributions to the field of dendritic cell biology.

Duration:00:05:54

[IMMUNOCAST] PILLARS OF IMMUNOLOGY

12/18/2017
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Dr. Patricia Gearhart discusses a 1965 paper from Michael Potter and the Michael Potter Homogenous Immunoglobulin workshops held at the NIH.

Duration:00:15:04

[IMMUNOCAST] PILLARS OF IMMUNOLOGY

11/20/2017
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Dr. James Hagman discusses a 1997 paper from the laboratory of Tak Mak, which first described the phenotype of T and B cells in mice lacking IRF4.

Duration:00:07:47

[IMMUNOCAST] PILLARS OF IMMUNOLOGY

10/23/2017
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Dr. Jane Buckner discusses 1974 papers from Bottazzo and MacCuish that were instrumental in determining that autoantibodies are directed at pancreatic islet cells in type I diabetes.

Duration:00:05:07