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Precision Evidence

Science Podcasts

At the Precision Evidence Podcast, we go beyond the abstract of medical papers to find medical research relevant and meaningful to patients and healthcare professionals and separate the news from the fake news in medicine. Finding, evaluating, and using clinical trials with relevant outcomes for patients and Evidence-Based Medicine is the focus of the podcast’s analysis of medical papers, discussions, and interviews with stakeholders. Hosted by Dr. Kim Kristiansen, M.D., and JG Staal. Twitter: @PrecisionEBM email us at podcast@precision-evidence.com

At the Precision Evidence Podcast, we go beyond the abstract of medical papers to find medical research relevant and meaningful to patients and healthcare professionals and separate the news from the fake news in medicine. Finding, evaluating, and using clinical trials with relevant outcomes for patients and Evidence-Based Medicine is the focus of the podcast’s analysis of medical papers, discussions, and interviews with stakeholders. Hosted by Dr. Kim Kristiansen, M.D., and JG Staal. Twitter: @PrecisionEBM email us at podcast@precision-evidence.com

Location:

Denmark

Description:

At the Precision Evidence Podcast, we go beyond the abstract of medical papers to find medical research relevant and meaningful to patients and healthcare professionals and separate the news from the fake news in medicine. Finding, evaluating, and using clinical trials with relevant outcomes for patients and Evidence-Based Medicine is the focus of the podcast’s analysis of medical papers, discussions, and interviews with stakeholders. Hosted by Dr. Kim Kristiansen, M.D., and JG Staal. Twitter: @PrecisionEBM email us at podcast@precision-evidence.com

Language:

English


Episodes

Clinically Relevance - Looking at Recent Research (11)

4/29/2021
Clinical trials and research should always aim to provide information that is meaningful and relevant for patients. However, researchers are rarely addressing that topic when presenting results from trials.In this episode, we look at published papers from high-ranking journals to get a sense of the extent of that problem. You may be surprised by our findings... We want to make it mandatory to state the researchers' clinical relevance levels ahead of the trial, mentioning what they will...

Duration:00:08:27

How to Get to Clinically Relevant Research (10)

3/26/2021
How to Get to Clinically Relevant Research The default method to evaluate clinical research is by statistical significance Unfortunately is statistical significance not related to the meaningfulness of the findings in the research and thereby to its meaningfulness for patients and healthcare If researchers stated ahead of starting the trial what they would consider clinically relevant, the reader could relate to that and agree or disagree with the researcher It would come from focusing...

Duration:00:17:32

Russia's Sputnik COVID19 Vaccine Trial - Efficacy and Limitations #9

2/23/2021
Russia's Sputnik COVID19 Vaccine Trial - Efficacy and Limitations The Russian Sputnik COVID19 vaccine interim analysis has been published in the prestigious medical journal The LancetEfficacy is comparable to vaccines like the Pfizer/BioNTech and Moderna vaccinesBut there are some serious concerns with the study and the published data reducing the usefulness of this vaccine and to whom it can be usedYou don’t want to miss this episode GET THE ABSTRACT SCREENING TOOL It can be a challenge...

Duration:00:08:36

Critical Appraisal of the Moderna COVID19 Vaccine Trial #8

2/2/2021
Critical Appraisal of the Moderna COVID19 Vaccine Trial There is a big interest in clinical research now due to the Covid19 pandemicEspecially the trails behind the Covid vaccines gain interest and is all over the newsIn this episode, we take a look at the published paper on the Moderna vaccine trial using our last episode of this podcast (#7) about the precision of the evidenceWe know from the news that the outcome in the Moderna vaccine trial is good with a reduction in risk at 94.1% by...

Duration:00:15:04

The Precision of Clinical Research #7

1/15/2021
You’ve probably often heard that “Clinical trials show..” or “ evidence support that..”Unfortunately, a research paper being published in a peer-reviewed medical journal is NOT a guarantee that it is clinically relevant - even if it is a high ranking journalAs it is often the case the devil is in the details, so itisnecessary to both read and evaluate the paper’s details and to put it into the context where you need the informationIn this episode, we will talk about the details you need to...

Duration:00:19:22

Covid-19 Vaccines Trials: Understanding the First Published Results #6

12/15/2020
Covid-19 Vaccines Trials: Understanding the First Published Results #6 GET THE ABSTRACT SCREENING TOOL It can be a challenge to screen papers for clinical relevance. As we go beyond the abstract in this podcast, we have created a screening tool you can use when reading an abstract from a clinical research paper. Using that tool enables you to quickly screen an abstract from a medical journal for clinical relevance selecting only those you want to read. At the same time, you will know...

Duration:00:14:27

Covid-19 Vaccines Trials and Press Releases – Looking Beyond the Efficacy - 5

12/2/2020
Results from clinical trials should be published in medical papers and not evaluated from selected information in press releasesWe still need a lot of information from the trials to be able to have a clear picture of the efficacy and safety of the Covid-19 vaccines, let alone the precision and clinical relevance of the findingsThe information presented in the press releases are not sufficient to make calculations on riskBut here is what you can find if you do it anyway GET THE ABSTRACT...

Duration:00:17:24

New Clinical Trial on Face Masks & Covid-19 - 4

11/24/2020
GET THE ABSTRACT SCREENING TOOL It can be a challenge to screen papers for clinical relevance. As we go beyond the abstract in this podcast, we have created a screening tool you can use when reading an abstract from a clinical research paper. Using that tool enables you to quickly screen an abstract from a medical journal for clinical relevance selecting only those you want to read. At the same time, you will know why you skipped the rest. Get it at...

Duration:00:13:53

Covid-19 Vaccine Trials and the Precision of the Evidence - 3

11/5/2020
youthat Links: https://www.fda.gov/emergency-preparedness-and-response/coronavirus-disease-2019-covid-19/covid-19-related-guidance-documents-industry-fda-staff-and-other-stakeholders https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2771091https://www.ajpmonline.org/article/S0749-3797(20)30284-1/fulltext#:~:text=This%20study%20found%20that%20the,(e.g.%2C%20social%20distancing) Notes: We will review published Covid-19 vaccine trials here at the Precision Evidence...

Duration:00:13:24

Face Masks: The Evidence and the Research - 2

11/5/2020
In this episode of the Precision Evidence Podcast, we look at the hot topic of evidence behind the use of face masks as we are in the middle of the Covid-19 pandemic. Does and can evidence-based medicine and clinical relevance play a role here? What do we know? What do we think we know? And what do we want to know? Links: https://advances.sciencemag.org/content/6/36/eabd3083 https://www.ncbi.nlm.nih.gov/research/coronavirus/publication/32829745...

Duration:00:14:57

Welcome to The Precision Evidence Podcast - 1

11/5/2020
The Precision Evidence Podcast is the podcast for those in healthcare interested in finding, evaluating, and using medical research that is meaningful to patients. Hosted by Dr. Kim Kristiansen, M.D. https://www.linkedin.com/in/kim-kristiansen - Twitter: @KKristiansenMD A family physician with 30 years of clinical experience, a peer reviewer for medical journals, and former TEDMED research scholar J.G Staal https://www.linkedin.com/in/jgstaal - Twitter: @HealthyEvidence Work in the...

Duration:00:08:26