SurgOnc Today®

This education episode of SurgOnc Today® features a roundtable discussion with input from surgical oncologists and a surgical oncology APPs on exploring the different ways APPs can contribute to a surgical oncology practice, both in the inpatient and outpatient settings.

In this episode of SurgOnc Today, Dr. Julie Hallet and Dr. Patricio Polanco, Chair and Vice-Chair of the HPB disease site, are joined by Drs. Ryan Ellis from Indiana University Scholl of Medicine and Allison Martin from Duke University. They will wrap the 2024 HPB year with us by reviewing the top HPB surgical oncology published this year. References/Resources: #5 NETTER-2 #4 NEOLUPANET #3 TRANSMET #2 PANDORINA #1 NORPACT

In this episode of SurgOnc Today®, Dr. Julie Hallet, Chair of the HPB Disease Site Work Group, and Dr. Patricio Polanco, Vice-Chair of the HPB Disease Site Work Group, are joined by Drs. Sajid Khan from Yale School of Medicine and Dr. Cecilia Ethun from UT Southwestern. They will wrap the 2024 HPB year by reviewing the top HPB surgical oncology published this year. References/Resources: #10: AMPLIFY https://www.nature.com/articles/s41591-023-02760-3 #9: Adjuvant therapy for IPMN-derived PDAC - https://ascopubs.org/doi/abs/10.1200/JCO.23.02313 #8: HELIX https://jamanetwork.com/journals/jama/fullarticle/2822555 #7: CAMINO https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00572-7/fulltext #5 : PANDAS/PRODIGE https://www.annalsofoncology.org/article/S0923-7534(24)03884-5/fulltext

Speaking of SurgOnc has a new home! New episodes can now be found under the Society of Surgical Oncology's podcast, SurgOnc Today, available on all major podcast platforms. Subscribe today to receive updates on new episode releases. In this new episode of Speaking of SurgOnc, Dr. Rick Greene discusses with Dr. Michael Bouvet and Dr. Kristin Cox the applicability of M5A-IR800 to target human gastric cancer, as reported in their article, "Targeting Patient-Derived Orthotopic Gastric Cancers with a Fluorescent Humanized Anti-CEA Antibody."

In this SSO Education Series episode of SurgOnc Today®, Dr. Seth Concors, an Assistant Professor of Surgical Oncology at Emory University interviews Dr. Aatur Singhi, an Associate Professor in the Divisions of Anatomic Pathology and Molecular Genomic Pathology, Director and Coordinator of Anatomic Pathology Research and Director of the UPMC Developmental Laboratory, who reviews the fundamentals of appendiceal pathology – reviewing recent changes relevant for clinical management.

In this episode of SurgOnc Today®'s Surgical Oncology Insight series, Dr. Shishir Maithel, Editor of Surgical Oncology Insight, discusses with Dr. Rita Mukhtar contemporary neoadjuvant therapy approaches to the treatment of breast cancer, with a focus on the interplay between imaging, systemic therapy, radiotherapy, and surgical management, as reported in her article, "The Neoadjuvant Approach to Treatment of Breast Cancer: Multidisciplinary Management to Improve Outcomes."

In this episode of SurgOnc Today®, Dr. Cord Sturgeon and Dr. Mahsa Javid are joined by Dr. Eduardo Guzmán Huerta, Dr. Juan Pablo Pantoja, and Professor Brian Lang to discuss factors affecting management of thyroid cancer with this group of experts who have a wealth of experience in different parts of the globe. Considerations affecting decision making and treatment options, adjuvant testing, adjuncts to surgery, overall costs and the system factors that need to be taken into account in the treatment and follow up of patients with thyroid cancer are explored. The discussed contributes towards advancing our understanding of worldwide processes and challenges in the management of thyroid cancer.

Dr. Rick Greene discusses with Dr. Heather Neuman and Dr. Alyssa Wiener the results of a randomized trial of topical pain approaches for radiotracer injections for breast cancer sentinel lymph node mapping, as reported in her article, "A Four-Arm Randomized Clinical Trial of Topical Pain Control for Sentinel Node Radiotracer Injections in Patients with Breast Cancer.”

In this episode of SurgOnc Today®, Prakash Pandalai, MD, Georgios Karagkounis, MD, and Fadwa Ali, MD, review the evolution of the Watch and Wait strategies in the management of rectal cancer patients with an emphasis on challenges, current clinical trials, and future directions.

This podcast was recorded on September 30, which is the National Day for Truth and Reconciliation in Canada and features an interview with Dr. Nadine Caron, who was the first Indigenous female surgeon in Canada. Dr. Caron shares her experience and perspectives from her leadership roles in health equity for First Nations peoples in Northern British Columbia with Dr. Cord Sturgeon and Dr. Mahsa Javid. The conversation explores the inequities in cancer care and cancer outcomes among Indigenous Peoples. Cancer incidence and survival among Indigenous People, gaps in knowledge, drivers of inequity, and a path forward for developing trust are discussed.

In this inaugural episode of the Surgical Oncology Insight series of SurgOnc Today®, Dr. Shishir Maithel, Editor of Surgical Oncology Insight, SSO's open-access journal, discusses with Dr. Brett Ecker the results of a systematic review and meta-analysis characterizing the incidence of cfDNA-positivity after resection of colorectal cancer liver metastases with quantification of its sensitivity and specificity for postoperative recurrence, as reported in his article, "The Prognostic Role of Post-operative cfDNA after Resection of Colorectal Liver Metastases: A Systematic Review and Meta-Analysis."

The surgical management of superficial soft tissue sarcoma require a multidisciplinary surgical team given the defect and reconstruction required from an extended resection to achieve negative margins. This team most often includes the primary surgeon (surgical oncology or orthopedic oncology) and a plastic surgeon. A critical decision in the treatment plan is whether or not to reconstruct immediately at the index operation or delay final reconstruction pending pathologic assessment of margins. In this podcast, we will focus on the multidisciplinary surgical approach for superficial sarcoma. We will highlight the role of delayed reconstruction and key clinical considerations in this approach.

Please listen in as Drs. Piltin, van Akkooi, and Hyngstrom discuss relevant clinical trial presentations from ASCO 2024 annual meeting and their impressions on the implications for surgical oncologists. Abstracts results discussed include the neoadjuvant NADINA and PIVOTAL trials as well as an initial report on upfront TIL therapy for stage IV patients.

In this episode of SurgOnc Today®, Dr. Patrick Sullivan is joined by Dr. Nicole Lopez and Dr. César Reátegui to discuss diverting ostomy. Current practice guidelines suggest that diverting ostomy is the standard of care in surgical management of rectal cancer after neoadjuvant therapy to minimize the risk of clinically significant leak which can then result in permanent colostomy. However, the risk of anastomotic leak after neoadjuvant chemoradiation ranges from 4-12% suggesting that most patients have unnecessary ostomy and additional surgery. With improvement of surgical techniques, utilization of robotic surgery and recent adoption of more TNT approaches, selective use of diverting ostomy will lead to improvement in QOL and decrease in health care costs with minimal impact on incidence of permanent colostomy.

In this podcast, the relatively new ASCO guidelines for breast cancer genetic testing will be discussed. The differences between these and other guidelines, such as ASBrS and NCCN, will be discussed. In addition, the different testing options and implications of positive results will be reviewed.

The podcast will explore different barriers to implement international cancer quality standards in developing countries, approach to overcome these barriers and how the SSO can help and support access to world class cancer care in developing countries. This episode is led by Dr. Cherif Boutros, who is joined by Dr. Nader Hanna and Dr. Joseph Espat.

In this episode of SurgOnc Today®, Dr. Julie Hallet, Chair of the SSO HPB Disease Site Working Group, reviews key updates and takeaways from the recent AHPBA Annual Meeting held in April 2024 in Miami. They are joined by Dr. Miral Grandhi, Dr. Amer Zureikat, Dr. Rebecca Snyder, and Dr. Katrina Duncan to review clinical trials on blood management for liver resection, biliary decompression for Klatskin tumors, and total venous deprivation to generate liver hypertrophy, as well as new data on genomics of pancreatic neuroendocrine tumors and bile liquid biopsy, and why evidence from clinical trials may not be adopted in HPB surgery.

In this episode of SurgOnc Today®, Akhil Chawla, MD, from Northwestern University, and a member of the SSO HPB disease site working group, is joined by Bas Groot Koerkamp, MD, PhD, from Erasmus Medical Centre and Knut Jørgen Labori, MD, PhD, from Oslo University Hospital. They discuss the details, similarities, and differences of their respective clinical trials for neoadjuvant therapy for pancreatic adenocarcinoma, NORPACT-1 and PREOPANC2. References/Resources: NORPACT-1 results: https://www.sciencedirect.com/science/article/abs/pii/S2468125323004053?via%3Dihub NORPACT-1 editorial: https://pubmed.ncbi.nlm.nih.gov/38604195/ PREOPANC-2 protocol: https://bmccancer.biomedcentral.com/articles/10.1186/s12885-021-08031-z PREOPANC-2 results : https://www.annalsofoncology.org/article/S0923-7534(23)04228-X/fulltext

In this episode of SurgOnc Today®, Deepa Magge, MD, and Abhineet Uppal, MD, provide a recap of highlights from the SSO Advanced Cancer Therapies conference held in February 2024.

In this episode of SurgOnc Today®, Yinin Hu, MD, and Sarah Fisher, MD, are joined by Neal Saunders, MD, and Heather Wachtel, MD, for a discussion of molecular testing for thyroid nodules and how to incorporate this adjunct into clinical practice.