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TXBioBytes from Texas Biomed

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Behind Steel Doors: High Containment Laboratories — TXBioBytes Podcast Episode 011

Developing vaccines and therapies to successfully treat some of the world’s deadliest diseases for which there are no known treatments or vaccines requires the safest laboratory in the world in which to study them. Texas Biomedical Research Institute is home to one of only six such labs in North America and the only operational BSL-4 lab owned by a private institution. Designed for maximum containment, BSL-4 labs offer a safe setting for scientists and the surrounding environment. This...


Who’s Afraid of the Big Bad Cough? — TXBioBytes Podcast Episode 010

A killer infectious disease called Pertussis is a bacterial infection that causes whooping cough. Vaccines had brought the numbers of cases down dramatically, but now they’re on the rise again and Texas Biomed animals and scientists are involved in the search for something better to treat this health problem that kills more than a hundred thousand infants a year. Pertussis has seen an alarming resurgence in the last decade. That’s surprising, given that a vaccine for this infectious...


Biomedical Science’s Instrumental Model: Rhesus Macaques — TXBioBytes Podcast Episode 009

Rhesus macaque monkeys are nonhuman primates that originate from the jungles of India. Hundreds of them live at the Southwest National Primate Research Center on the Texas Biomedical Research Institute campus. Macaques are useful for studying diseases from HIV to Ebola. While the macaques live in indoor/outdoor housing, the scientific work performed on their samples takes place in a lab setting.


Texas Biomedical Forum: Women Who Support Science — TX BioBytes Podcast Episode 008

The Texas Biomedical Forum started in 1970 as a group of women on a mission – to support the hope and promise of life-saving research at Texas Biomedical Research Institute. What started as the brainchild of a handful of women has turned into an organization that is more than 300 members strong. The Forum raises hundreds of thousands of dollars each year in support of the science at Texas Biomed. The purpose of the Texas Biomedical Forum continues to be to support the Texas Biomedical...


Baboons: 50 years of Helping Human Health — TXBioBytes Podcast Episode 008

The baboon is widely used as a model for the study of genetics of complex diseases, and continues as a successful model for many chronic and infectious diseases, including insulin resistance, obesity, heart disease, hypertension and osteoporosis. This resource has also been used to further studies in contraception, tissue engineered heart valves, epilepsy, immune system aging, pertussis, sepsis and ischemic stroke. SNPRC provides pedigreed baboons for research projects investigating the...


Marmosets: Miniature but Mighty — TXBioBytes Podcast Episode 006

The Southwest National Primate Research Center at Texas Biomedical Research Center is one of only two national primate research centers that provide marmoset research resources. Our resources include the only large population (>70) of aged marmosets (>10 years) in the country. Common marmosets have been a biomedical research resource since the early 1960’s, used predominately in studies of infectious disease, immunology and neuroscience. Historically, they have been a more commonly used...


Unraveling a Childhood Medical Mystery: Kawasaki Disease — TXBioBytes Podcast Episode 005

Kawasaki disease is a rare childhood illness that can cause serious heart trouble for patients later in life. Now, Texas Biomedical Research Institute and Children's Hospital of San Antonio are teaming up to research possible interventions to cut down on the serious side effects of the disease. Dr. Mark Gorelik is a pediatric rheumatologist. He uses a mouse model now housed at Texas Biomed. Jean Patterson, Ph.D., is helping him on the project. Listen to learn more about this exciting...


What do Snails have to do with it? — TXBioBytes Podcast Episode 004

Schistosomiasis is an important tropical disease caused by schistosome trematodes (a parasitic blood fluke). Those parasites are found in South America and the Caribbean, sub-Saharan Africa, the Middle East, and Southeast Asia. An estimated 200 million people worldwide are infected with schistosomes and 200,000 people die each year. Schistosomiasis is a waterborne disease. Infected freshwater snails release larvae (cercariae) which can infect humans during their water related activities....


Much Ado About Malaria – TXBioBytes Episode 002

Malaria is a mosquito-borne disease that kills hundreds of thousands of people around the world every year. Scientist Ian Cheeseman, Ph.D., of Texas Biomed specializes in the genetics of the parasite that causes malaria. His newest study published in the journal Genome Biology and Evolution was recently highlighted in the Editors Choice section of the prestigious journal Science. “At the basic level we simply do not know what’s in a malaria infection, even though this has profound...


TB or not TB – TXBioBytes Episode 001

Texas Biomedical Research Institute in San Antonio is a new focal point for TB research, with scientists studying the disease from dozens of angles, researching new therapies and a better way to vaccinate people against the insidious infection that targets the lungs. Tuberculosis is an ancient health threat that’s still claiming several thousand lives each day around the globe. It’s the world’s deadliest infectious disease. And TB isn’t just a third world concern. It’s an American problem,...