This Week in Virology

TWiV reviews lymphocytic choriomeningitis virus seroprevalence among urban pregnant women and newborns in Philadelphia, and a functional translation initiation complex encoded in the genome of giant viruses that drives synthesis of viral structural proteins. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Angela Mingarelli Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education (email)LCMV seroprevalencefunctional vIF4F Ribosomal proteinsJolene Weekly Picks Angela – "The Song of the Cell" by Siddhartha Mukherjee. Kathy – Fitbit for farts (WSJ and 1° article) Rich – The Password That Lets Caterpillars Hide in an Ant's Lair Vincent – Astrophysics for People in a Hurry by Neil deGrasse Tyson Listener Pick Larry – Get an early start! (primary article) Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss several states and the governor of Pennsylvania suing HHS over changes in the childhood vaccination schedule, the vaccine derived type 2 poliovirus outbreak in Pakistan and implications for the global withdrawal of the oral poliovirus vaccine, and the outbreak of Candida, then Dr. Griffin deep dives into recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, how to access and pay for Paxlovid, when to use steroids for treating influenza, long COVID treatment center, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode changesSidesteps Unqualified failureVaccine-Derived Poliovirus Type 2Must BeWastewater Wastewatercases and outbreaksMeasles Dashboard UtahMeasles CasesjpgWeeklyMeaslesFACTS MeaslesMeasles Presumptive evidence Contraindications and precautionschildhood vaccinesVaccination:evidence show11 pathogensrespiratoryactivitycliff notes OPTION 211 pathogens Respiratory DiseasesrespiratoryNetVaccines for Adults Economic Analysis Respiratory Diseases11 pathogensdeathsData Channelnational and regionalvariant trackergenomespreeclampsiaWhere EUAcenter CDC QuarantineNIHcheckerpatients accessProCoverage Infectious Disease Society guidelinessafetyimmunocompromisedcorticosteroidsrespiratory virusshortages Anticoagulationevidence basedhotlineThe answers:US house representativeLetters read pdfJolene Ramsey Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV explains how vaccine-induced thrombotic thrombocytopenia develops from antibodies to adenovirus and somatic hypermutation, and castration by a viral protein tyrosine phosphatase that targets a host cell cycle checkpoint protein. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education (email)endangerment findingsue EPApandemic preparedness and biodefenseModerna mRNA rejectionVITT Parasitc castration PolydnavirusesLetters readJolene Weekly Picks Brianne – The effect of seeing scientists as intellectually humble on trust in scientists and their research Rich – The Great Bridge: The Epic Story of the Building of the Brooklyn Bridge by David McCullough Alan – Recipes from the American South, by Michael Twitty Vincent – Why Returning From Mars ls Impossible – Richard Feynman's Warning Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss reversal of last week's no review decision on a flu mRNA vaccine by Vinjay Prasad, appointment of Jay Bhattacharya as CDC director, no experience required, and already detectable reduction in hepatitis B virus vaccination rates, then Dr. Griffin then deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, how to access and pay for Paxlovid, the consequences of measles infection on immune amnesia (shout out to Immune 26), long COVID treatment center, where to go for answers to your long COVID questions, long COVID effect on fertility and type 2 diabetes and contacting your federal government representative to stop the assault on science and biomedical research. Click arrow to play Download TWiV 1298 (26 MB .mp3, 43 min) Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Agrees to ReviewWall Street JournalAccess New wire N.I.H. Director Reductionfailed Wastewatercases and outbreaksMeasles DashboardFlorida College300 casesActively SpreadingMeasles CasesjpgWeeklyMeaslesFACTS MeaslesMeasles Presumptive evidence Contraindications and precautionschildhood vaccinesVaccination:evidence showMeasles 2025diminishesImmune 26 Incompletemeasles-associated immune suppression11 pathogens respiratoryactivitycliff notes OPTION 211 pathogens Respiratory DiseasesrespiratoryNetVaccines for Adults Economic Analysisafter11 pathogensdeathsData Channelnational and regionalvariant trackergenomesAntiviral PrescriptionWhere EUAcenter CDC QuarantineNIHcheckerpatients accessProCoverage Infectious Disease Society guidelinessafetyimmunocompromisedrespiratory virusshortages Anticoagulationevidence basedhotlineThe answers:impactFollowingUS house representativeLetters read pdfJolene Ramsey Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV explains the observation that filamentous virions act as non-infectious interfering particles to modulate papillomavirus infection, and transmission of monkeypox virus from fire-footed rope squirrels to sooty mangabeys. Hosts: Vincent Racaniello, Alan Dove, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education (email) FDA refuses to review Oz measles vaccine callinterfering virus particlespotential MPXV reservoirMPXV reservoir Letters readJolene Weekly Picks Brianne – Silo TV series Kathy – Ancient RNA expression profiles from the extinct woolly mammoth and Ancient host-associated microbes obtained from mammoth remains Alan – Ubik, by Philip K. Dick Vincent – Starry Messenger by Neil deGrasse Tyson Listener Pick Beth – Iceland crime fiction authors Yrsa Sigurdardottir and Ragnar Jonasson Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello are shocked by recent events, including Dr. Oz's appeal for measles vaccination, Vinjay Prasad's unilateral rejection of Moderna's mRNA influenza vaccine application, and the increasing number of New World screw worm cases, then Dr. Griffin then deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, how to access and pay for Paxlovid, the number of measles deaths in Mexico, long COVID treatment center, where to go for answers to your long COVID questions, choroid plexus alterations in long COVID association with neuropathologies and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Dr. Oz's appealrefuses Hepatitis B Vaccination'dialed in'promotesMexicoscrewworm Wastewatercases and outbreaksMeasles DashboardMeasles CasesjpgWeeklyMeaslesFACTS MeaslesMeasles Presumptive evidence Contraindications and precautionschildhood vaccinesVaccination:evidence show'irreversible'28 have died11 pathogensrespiratoryactivitycliff notesrisk OPTION 211 pathogens Respiratory DiseasesrespiratoryNetpreventionVaccines for Adults Economic Analysis11 pathogensdeathsData Channelnational and regionalvariant trackergenomesWhere EUAcenter CDC QuarantineNIHcheckerpatients accessProCoverage Infectious Disease Society guidelinessafetyimmunocompromisedrespiratory virusshortages Anticoagulationevidence basedhotlineThe answers:associationsUS house representativeLetters read pdfJolene Ramsey Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV reviews a survey conducted in Cambodia's floating villages to explore measles vaccination perceptions and willingness to consider novel vaccination approaches, and how a prophage defends against an infecting phage. Hosts: Vincent Racaniello, Rich Condit, Brianne Barker, and Jolene Ramsey Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education ASV 2026(email)US measles outbreak Tracking Poll Measles vaccination perceptionsProphage defendsLetters readJolene Weekly Picks Brianne - Libib book cataloging app Rich - The Mysterious Case of Rudolf Diesel: Genius, Power, and Deception on the Eve of World War I by Douglas Brunt Jolene - Ellie Jameson artwork and Redbubble Vincent - Recursion by Blake Crouch Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update during Ground hog week, Dr. Griffin and Vincent Racaniello are back to discuss the measles outbreak in South Carolina, American Academy of Pediatrics vaccine recommendations and shingles vaccine and the reduction of dementia, then deep dives into recent statistics RSV, influenza and SARS-CoV-2 infections, the Wastewater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, how to access and pay for Paxlovid, estimated effectiveness of this year's COVID-19 vaccine, long COVID treatment center, where to go for answers to your long COVID questions, long COVID in children, the potential benefits of metformin to reduce disease severity following SARS-CoV-2 infection in obese and overweight patients and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode groundhogsearly springAAP Recommended RecommendeddementiaDutch dairy cow Wastewatercases and outbreaksMeasles DashboardMeasles CasesjpgWeeklyMeaslesFACTS MeaslesMeasles Presumptive evidence Contraindications and precautionschildhood vaccinesVaccination:evidence show11 pathogensrespiratoryactivityclift notes OPTION 211 pathogens Respiratory DiseasesrespiratoryNetVaccines for Adults Economic Analysis11 pathogensdeathsData Channelnational and regionalvariant trackergenomesEffectivenessWhere EUAcenter CDC QuarantineNIHcheckerpatients accessProCoverage Infectious Disease Society guidelinessafetyimmunocompromisedrespiratory virusshortages Anticoagulationevidence basedhotlineThe answers:reinfectionhere to stay Early administrationMetforminmayOverweight or Obese PreventinghighlightsUS house representativeLetters read pdfJolene Ramsey Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV reviews the finding in Sweden that immunization against cervical cancer with human papillomavirus vaccine also protects the non-immunized, and methyl salicylic acid as a key volatile molecule that attracts parasitoid wasps to rice and other crops to destroy destructive leafhoppers, and is down-regulated by virus infection to enable virus spread. Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education ASV 2026(email)Host adaptations to viral infections William Foege Peter Duesbergover 10,000 PhDsHPV vaccinationrice's volatile emissionsLetters readJolene Weekly Picks Kathy - The Beak of the Finch, by Jonathan Weiner Rich - Washington: A Life by Ron Chernow Vincent - The Man from Beijing by Henning Mankell Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss with disgust the decline and fall of American public health and the rise of "only me" when highlighting completion of the US withdrawal from the WHO and possibility of making IPV and MMR optional vaccines, before Dr. Griffin then deep dives into recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, Europe losing its measles elimination status, first measles death in Mexico, almost 1000 measles cases in South Carolina, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, the effectiveness of this season's influenza vaccine, where to go for answers to your long COVID questions and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode completes withdrawalPolio FrighteningErosion WastewaterlosingElimination) Infectious Traveler789cases and outbreaksMeasles CasesjpgWeeklyMeaslesFACTS MeaslesMeasles Presumptive evidence Contraindications and precautionschildhood vaccinesVaccination:evidence showfirst measles cases of year First measles death11 pathogensrespiratoryactivitycliff notesVaccine Effectiveness OPTION 211 pathogens Respiratory DiseasesrespiratoryNetVaccines for Adults Economic Analysis11 pathogensdeathsData Channelnational and regionalvariant trackergenomes Effectiveness and DurabilityWhere EUAcenter CDC QuarantineNIHcheckerpatients accessProCoverage Infectious Disease Society guidelinesNirmatrelvir-ritonavirsafetyimmunocompromisedrespiratory virusshortages Anticoagulationevidence basedhotlineThe answers:US house representativeLetters read pdfJolene Ramsey Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV explains emergence of a neurovirulent double recombinant from the 'improved' nOPV2 in Uganda, and efficiency of viral entry determined whether cells are latently or lytically infected with cytomegalovirus. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education ASV 2026(email) 2023 IMB reportHCMV latency establishmentLetters readJolene Weekly Picks Brianne – Dark Matter by Blake Crouch Rich – Sequoiadendron giganteum; Sequoia & Kings Canyon National Park Alan – The Murderbot Diaries book series, by Martha Wells Vincent – Surely You're Joking, Mr. Feynman! Listener Picks Rocky – Cheetah mummies found in cave (Nature, National Geographic) Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss screwworm, how the shingles vaccination slows biological aging (for all of you who want to reset 'the clock' and live forever…..you know who you are Musk, Bezos) and getting one dose of the HPV vaccine, then Dr. Griffin then deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how losing our elimination status is the cost of doing business (going for broke is never a good business model !) where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, the effectiveness of this season's influenza vaccine, where to go for answers to your long COVID questions and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode official CDC Health Advisoryslower biological agingOne HPV Vaccine Dose Herd effectCommercial and Backyard FlocksWild Birdsmajor commercial WastewaterNotes from the FieldMeasles VirusNotes from the FieldMeasles Outbreakcases and outbreaksjpgMeasles Cases'cost of doing business'WeeklyMeaslesFACTS MeaslesMeasles Presumptive evidence Contraindications and precautionschildhood vaccinesVaccination:evidence showcoverage gaps11 pathogensrespiratoryactivityclift notesprevent severe disease Interim vaccine effectivenesssubclade Kmoderate protection OPTION 211 pathogens Respiratory DiseasesrespiratoryNetVaccines for Adults Economic Analysis11 pathogensdeathsData Channelnational and regionalvariant trackergenomesWhere EUAcenter CDC QuarantineNIHcheckerpatients accessProCoverage Infectious Disease Society guidelinessafetyimmunocompromisedrespiratory virusshortages Anticoagulationevidence basedhotlineThe answers:US house representativeLetters read pdfJolene Ramsey Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV explains how the dengue virus protein NS1 alters Aedes aegypti midgut permeability and favors virus dissemination, and achieving a complete hepatitis B virus cure in chronic hepatitis B virus-infected humanized mice by using a capsid assembly modulator. Hosts: Vincent Racaniello, Alan Dove, and Angela Mingarelli Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education ASV 2026(email)alters mosquito midgut permeabilitycapsid assembly modulatorLetters readJolene Weekly Picks Angela – How hibernating bears maintain muscle mass Alan – The flood of Chinese grad students in the 2000s was a boon to US students. Vincent – Feynman Lectures on Physics Listener Picks David – Stewart Cheifet, Host of TV's 'Computer Chronicles,' Dies at 87 Charles – Last Year, and the Year to Come Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello are bewildered and dismayed by RFK Jr's announced changes in the routine childhood immunization schedule, though not unpredicted, and highlight the science and evidence which eviscerate these changes, then deep dives into recent statistics on the measles epidemic- in particular in South Carolina, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, estimated societal burden of COVID-19 illness, deaths and hospitalizations, benefit of maternal COVID-19 vaccination, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, neurodevelopmental consequences of in-utero SARS-CoV-2 infection and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Danish cheeses Norovirus Maternal Vaccine Receipt 124 New Measlessoar in South Carolina Wastewatercases and outbreaksMeasles CasesjpgWeeklyMeaslesFACTS MeaslesMeasles Presumptive evidence Contraindications and precautionschildhood vaccinesVaccination:evidence show11 pathogensrespiratoryactivitycliff notespediatric flu deaths OPTION 2Best Flu Drug2025-202611 pathogens Respiratory Diseasesuniversal nirsevimab prophylaxisSafety of RSVpreF VaccinationRSV vaccine saferespiratoryNetVaccines for Adults Economic Analysis11 pathogensdeathsData Channelnational and regionalvariant trackergenomesBA.3.2, XFG, and NB.1.8.1Effectiveness of 2024–2025 Seasonal mRNA-1273Where EUAcenter CDC QuarantineNIHcheckerpatients accessProCoverage Infectious Disease Society guidelinessafetyimmunocompromisedcorticosteroids in influenza-associatedrespiratory virusshortages Anticoagulationevidence basedhotlineThe answers:Postacute Sequelae of SARS-CoV-2 InfectionUS house representativeLetters read pdfJolene Ramsey Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV explain the tracing of 2500 years of human betaherpesvirus 6A and 6B diversity through ancient human DNA, the effect of shingles vaccination at different stages of the dementia disease course. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education ASV 2026AncientFirst through sixthdifferent stages of dementiaLetters readJolene Weekly Picks Brianne – TWiM Annotations and Resources Book for Teaching Alan – Starter Villain, by John Scalzi Rich – Redshirts: A Novel with Three Codas, by John Scalzi Vincent – Mina's Matchbox by Yoko Ogawa Listener Picks Rona – Maggie and Millie and Molly and May by Natalie Merchant Owen – How to get the vaccines you need now Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello are bewildered and dismayed by RFK Jr's announced changes in the routine childhood immunization schedule, though not unpredicted, and highlight the science and evidence which eviscerate these changes, then deep dives into recent statistics on the measles epidemic- in particular in South Carolina, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, estimated societal burden of COVID-19 illness, deaths and hospitalizations, benefit of maternal COVID-19 vaccination, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, neurodevelopmental consequences of in-utero SARS-CoV-2 infection and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Childhood Immunization Schedule Recommended Child and Adolescent Immunization Schedule Kennedy Scales BackRFK Jr. Goes Againan Essential Safety Net Effectiveness and ImpactRotavirusHepatitis A Meningococcal VaccinationRecommendationschildhood vaccine recommendations remain unchanged Wastewatercases and outbreaksMeasles Casesmeasles cases rise by 26jpgWeeklyMeaslesFACTS MeaslesMeasles Presumptive evidence Contraindications and precautionschildhood vaccinesVaccination:evidence show11 pathogensrespiratoryactivitycliff notes2025-202611 pathogens Respiratory DiseasesNetVaccines for Adults Economic AnalysisdeathsData Channelnational and regionalvariant tracker Estimated BurdenRole of Vaccination in Maternal and Perinatal OutcomesWhere EUAcenter CDC QuarantineNIHcheckerpatients accessProCoverage Infectious Disease Society guidelinessafetyimmunocompromisedrespiratory virusshortages Anticoagulationevidence basedhotlineThe answers:consequences of in-uteroUS house representativeLetters read pdfJolene Ramsey Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV reviews compelling virology themes for 2024, as heard in our 98 episodes, including 22 guests. Hosts: Vincent Racaniello and Kathy Spindler Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education ASV 2026TWiV 1199TWiV 1191TWiV 1197TWiV 1203TWiV 1205TWiV 1209TWiV 1211TWiV 1215TWiV 1217TWiV 1219TWiV 1221TWiV 1223TWiV 1225TWiV 1227TWiV 1231TWiV 1233TWiV 1241TWiV 1243TWiV 1245TWiV 1285TWiV 1187TWiV 1207TWiV 1249TWiV 1263TWIV 1233TWiV 1213TWIV 1237Chari CohenStephan Urban, Thomas TuTWiV 1279themes/highlightsTWIV 1195TWiP 254YouTube excerpt, DDD PhotographyDespommier's Parasitic DiseasesTWiV 1193TWiV 1257TWiV 1259TWiV 1211TWiV 1273TWiV 1209TWiV 1265TWiV 1267TWIV 1241TWiV 1273TWiV 1275TWiV 1279TWiV 1269TWiV 1243TWiV 1261TWiV 1181Letters readJolene Weekly Picks Kathy – APOD for 1/1/2026; American Kestrals Put the Cherry on Top Primary article (open access) Vincent – Science in Your Own Back Yard by Elizabeth Cooper Listener Picks Bill – They did the Monster Slash and Elle Cordova Rona – The married scientists torn apart by a COVID bioweapon theory Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

Recording after the ball drops, Dr. Griffin and Vincent Racaniello wish everyone a Happy New Year, discuss an evidence-based approach to teaching and practice medicine and reminisce on the history of vaccine development and use before their discussion about the whooping cough outbreak of 2025 in the US and falling levels of tetanus vaccination, then Dr. Griffin then deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how NY state reported the greatest number of influenza confirmed infections ever in one week during the week ending Dec 20, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Evidence-Based Medicine:28,000 whooping cough casesDevelopments by Yearnotable diseasestetanus vaccination rates decline Wastewatercases and outbreaksMeasles CasesjpgWeeklyMeaslesFACTS MeaslesMeasles Presumptive evidence Contraindications and precautionschildhood vaccinesVaccination:evidence show11 pathogensrespiratoryactivityMost Flu Cases Ever Recorded in One Weekcliff notes2025-202611 pathogens Respiratory DiseasesNetVaccines for Adults Economic Analysis Nirsevimab vs RSVpreF VaccineFrequently Asked11 pathogensdeathsData Channelnational and regionalvariant trackergenomesBA.3.2, XFG, and NB.1.8.1Where EUAcenter CDC QuarantineNIHcheckerpatients accessProCoverage Infectious Disease Society guidelinessafetyimmunocompromisedrespiratory virusshortages Anticoagulationevidence basedhotlineThe answers:US house representativeLetters read pdfJolene Ramsey Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV explains studies which reveal that Inhibition of CXCL10 and IFN-γ mitgates myocarditis associated with SARS-CoV-2 mRNA vaccination, and identification of a bacteriophage T7 protein that antagonizes the DNA restriction system of the host by mimicking B form DNA. Hosts: Vincent Racaniello and Jolene Ramsey Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education ASV 2026vaccine-associated myocarditisDNA restriction of hostmimics DNALetters readJolene Weekly Picks Jolene – Book series Dinosaur Therapy, Dinosaur Philosophy, & Dinosaur Friendship Vincent – One Plus One Equals One: Symbiosis and the evolution of complex life by John Archibald Listener Picks Terry – Arcadia by Tom Stoppard Greg – Charctic Interactive Sea Ice Graph | National Snow and Ice Data Center Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

Calling out "Happy Christmas to all and to all a good-night, Dr. Griffin and Vincent Racaniello discuss high path influenza in dairy herds in Wisconsin and Marburg virus in Ethiopia before Dr. Griffin then deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the slightly higher association of COVID-19 infection with death than following influenza infection, benefit of passive infant immunization with niresevimab, association of COVID-19 vaccine immunogenicity protection against severe disease in vulnerable populations, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, effect of remdesivir and nirmatrelvir/ritonavir on COVID-19 associated mortality, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Dairy HerdSequencing ResultsOutbreak in Ethiopia Wastewatercases and outbreaksMeasles CasesjpgWeeklyMeaslesFACTS MeaslesMeasles Presumptive evidence Contraindications and precautionschildhood vaccinesVaccination:evidence show11 pathogensrespiratoryactivityclift notesCDC recommends2025-202630-day Mortality Risk11 pathogens Respiratory DiseasesrespiratoryNetVaccines for Adults Economic Analysis Nirsevimab vs RSVpreF VaccineFrequently Asked11 pathogensdeathsData Channelnational and regionalvariant trackergenomesBA.3.2, XFG, and NB.1.8.1COVID-19 vaccine immunogenicity and protectionWhere EUAcenter CDC QuarantineNIHcheckerpatients accessProCoverage Infectious Disease Society guidelinesremdesivir and nirmatrelvir/ritonavirsafetyimmunocompromisedrespiratory virusshortages Anticoagulationevidence basedhotlineThe answers:big funding boostUS house representativeLetters read pdfJolene Ramsey Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.