Life as a Nephrology Professional

Join us in this episode as we explore the intriguing world of pediatric kidney health with Dr. Casey Rebholz, an esteemed expert in epidemiology and clinical research. Discover recent insights from the Journal of Renal Nutrition (linked here) regarding the impact of dietary protein-rich foods on kidney disease progression in children. Dr. Rebholz shares valuable perspectives on the significance of protein metabolites, the importance of metabolite testing, and effective strategies for preserving renal function in pediatric patients with chronic kidney disease (CKD). Tune in for a deep dive into protecting and optimizing kidney health in our young population. Host: Osama El Shamy, MD Contributor: Casey Rebholz, PhD, MS, MNSP, MPH

Kidney transplants are a life-changing intervention, but do not work immediately; this delayed graft function has serious implications for transplant programs, patient outcomes, and organ waste. Tune in as our host Dr. Anna Gaddy interviews Dr. Matthew Cooper to discuss the research and implications behind his co-authored special report, “Understanding Delayed Graft Function to Improve Organ Utilization and Patient Outcomes: Report of a Scientific Workshop Sponsored by the National Kidney Foundation”, published in the March 2024 issue of AJKD. Kidney transplant care teams can work collaboratively to say ‘yes’ to transplant and decrease the number of viable kidneys that are otherwise discarded. Read the article, listen in, and bring this important conversation to your kidney transplant community. Host: Anna Gaddy, MD, FASN, FNKF Contributor: Matthew Cooper, MD, FACS, FAST, FNKF

Experience a dynamic panel discussion on advancing kidney health equity and increasing access to transplants in our recorded webinar, presented by the NKF and National MOTTEP. In 2021, there were 786,000 patients living with kidney failure, yet fewer than 25,000 received a transplant that year. Black people are more than 4 times as likely as White people to have kidney failure. To help address these disparities, the NKF and National MOTTEP (Minority Organ Tissue Transplant Education Program) are teaming up to educate on the importance of building trustworthiness and community partnerships to advance kidney health equity and increase access to transplants for all. Panelists: Clive O. Callender, MD; Kirk Campbell, MD, FASN; Karim Ali, SA; Tanjala S. Purnell, PhD, MPH, FASN; Morgan Reid, MSJ; Velma Scantlebury, MD, FACS, GCM

In part two of this 2-episode mini-series, our panelists discuss the recent approval of tenapanor for hyperphosphatemia management in patients on dialysis by the United States Food & Drug Administration (FDA). Tune into this discussion where our expert panelists share how the phosphate absorption inhibitor (PAI) works, factors to consider when integrating this agent into a patient’s treatment regimen, and how it may impact hyperphosphatemia management moving forward. Learning objectives: Host: Sam Kant, MD Guests: Alexander Leidner, MD; Annabel Biruete, RD, PhD; Alex Berrios Supported by a grant from Ardelyx. Don't miss Part 1 in this series! Listen to: Patient & Clinician Experiences with Hyperphosphatemia: The Current Landscape

In part one of this 2-episode mini-series, our panelists discuss the current landscape of hyperphosphatemia management for patients on dialysis – including what’s working well and where there is room for improvement. Tune into this discussion where our experts share their experiences with leveraging team-based and person-centered approaches to managing hyperphosphatemia from the perspectives of nephrologist, dietitian, and patient. Learning objectives: Host: Sam Kant, MD Guests: Alexander Leidner, MD; Annabel Biruete, RD, PhD; Alex Berrios Supported by a grant from Ardelyx. Don't miss Part 2 in this series! Listen to: Hyperphosphatemia Treatment Innovations: Phosphate Absorption Inhibitor (PAI)

In this episode, experts in the field—Dr. Shivam Joshi, Dr. Holly Kramer, Dr. Blake Shusterman, and professional chef Duane Sunwold—explore the upcoming issue of Advances in Kidney Disease and Health (AKDH), titled "Rethinking the Renal Diet." Tune into this discussion that revolves around the critical need for a shift in dietary perspectives for kidney health, debunking misconceptions and highlighting the benefits of embracing plant-based diets. The team recognizes the historical focus on restriction in the renal diet and offers a new way of thinking that aligns with the preference for "more" over "less." This episode aims to inspire a reevaluation of the conventional "renal diet" and encourages health practitioners to prioritize dietary interventions for improved patient outcomes.

2023 has been a stupendous year in the realm of nephrology research. Host Sam Kant welcomes editors from the National Kidney Foundation’s family of journals to share reflections on the year, while also discussing what listeners can look forward to in research and publication in 2024.

November 2023 marks the 45th anniversary of the International Society for Renal Nutrition and Metabolism (ISRNM)! To celebrate, our host is joined by a team of editors and authors from the Journal of Renal Nutrition’s 45th Anniversary ISRNM Special Supplement, which highlights key themes including plant-dominant diets, microbiome modulation, and how to approach nutrition in patients who select conservative care. Join this discussion on key takeaways from three JRN articles and learn how clinicians can turn this research into action to improve patient experiences and outcomes. Articles features in the episode include: New Insights Into Dietary Approaches to Potassium Management in Chronic Kidney DiseaseTargeting the Gut Microbiota in Kidney Disease: The Future in Renal Nutrition and MetabolismNutritional and Dietary Management of Chronic Kidney Disease Under Conservative and Preservative Kidney Care Without Dialysis Host: Natasha Dave, MD Guests: Kam Kalantar-Zadeh, MD, PhD, MPH; Angela Wang, MD, PhD; Brandon Kistler, PhD, RD, MS; Keiichi Sumida, MD, MPH, PhD; Kelly Lambert, PhD, MS

This episode deep-dives into a recent AJKD article entitled Fatigue in Patients Receiving Maintenance Hemodialysis: A Review. Our host is joined by a current hemodialysis patient and two of the article’s co-authors to explore and share all about interdialytic and postdialysis fatigue. Listen in as our host and contributors ask the tough questions and review the data around interventions ranging from dialysate composition and temperature to treating depression. Most importantly, hear how the research intersects with a kidney patient’s lived experience in this episode of the Life as a Nephrologist podcast. Contributing Authors: Dr. Susan Hedayati and Dr. Parker Gregg Contributing Patient: Dr. David Perchinsky Podcast Host: Dr. Natasha Dave

In this episode, our host is joined by members of the Kidney Medicine editorial team and author, Dr. Chintan Shah, to tackle the “forgotten electrolyte”, magnesium. The panel highlights the importance and relevance of magnesium through discussion of four published journal articles, including: SGLT2 Inhibitors in Management of Severe Hypomagnesemia in Patients Without Diabetes: A Report of 4 CasesSodium Glucose Cotransporter 2 Inhibitors and Management of Refractory Hypomagnesemia Without Overt Urinary Magnesium Wasting: A Report of 2 CasesDialysate Magnesium and Coronary Artery Calcification, Bone Mineral Density, and Cramping in Maintenance Hemodialysis: A Quasi-experimental StudySerum Magnesium Levels and Cardiovascular Outcomes in Systolic Blood Pressure Intervention Trial Participants Host: Sam Kant, MD Guests: Daniel Weiner, MD, MS; Jenny Shen, MD, MS; David Drew, MD, MS; Chintan Shah, MD

Increased prevalence and treatment modalities for kidney disease, shifts in priorities, clinical demands, and changes in funding have altered how we approach nephrology education. We are witnessing a massive shift in how education is delivered and implemented; innovative methods now exist outside the classroom and beyond the medical wards. Our focus in this episode is a journal issue of Advances in Kidney Disease and Health*, entitled Nephrology Education for the 21st Century. The study of nephrology is already a daunting undertaking; how can we develop novel ways of teaching at all levels of higher education? Co-editors Drs. Niralee Patel and Staci Leisman join host Dr. Sam Kant to discuss and explore examples of restructured nephrology curricula and learning methods in undergraduate, graduate, fellowship, and continuing medical education spaces. *Formerly called Advances in Chronic Kidney Disease.

This episode explores the 2021 NKF Kidney Disease Outcomes Quality Initiative Commentary (KDOQI) on the Kidney Disease Improving Global Outcomes (KDIGO) guideline for glomerular diseases. The KDOQI commentary provides discussion on issues that are specific for implementation of the KDIGO guidelines in US healthcare settings. Tune in is as our host Dr. Natasha Dave dives into the commentary with Co-Chairs Dr. Bill Whittier, Rush University Medical Center in Chicago, and Dr. Laurence Beck, Boston Medical Center.

In this episode, journey with us on an expedition filled with unexpected challenges, daunting obstacles, and arduous travels: the journey of a manuscript on its way to publication. Guiding us there and back again are the editors of Kidney Medicine, National Kidney Foundation’s open access journal focused on clinical medicine in nephrology and hypertension, which includes original research, case reports, and review articles. Host: Sam Kant, MD Guests: Daniel Weiner, MD, MS; Jenny Shen, MD, MS; David Drew, MD, MS

This is the final episode of a series celebrating the 40th anniversary of the American Journal of Kidney Disease, an official journal of the National Kidney Foundation. AJKD is recognized worldwide as a leader in clinical nephrology content, publishing original investigations describing the latest findings related to kidney diseases, hypertension, dialysis therapies, and kidney transplantation. Join us as we discuss how the AJKD has helped bring the patient experience and patient voice to researchers and clinicians in order to enhance the quality of research ideas and improve the quality of care delivered. Host: Sam Kant, MD Guests: Harold Feldman, MD, Dena Rifkin, MD, MS & John Ortiz

Too many kidney patients face significant barriers to accessing lifesaving care. Research shows longer, more frequent dialysis done in the home yields better kidney health outcomes and improved quality of life for patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD). Yet, patients do not have equal access to this treatment option. Join us as we unpack disparities in today’s kidney disease treatment paradigm and discuss the steps, we, as nephrologists, need to take to alleviate access issues and help make the options of in-home treatment a reality for more patients.

In this episode, we are joined by a hardworking group of individuals who are passionate about advocating for patients with kidney disease. Our guests focus on the ways in which AJKD has communicated health policy updates in the last four decades and discuss key developments in kidney disease and health policy. They explain some of the current policy challenges facing the kidney disease community today. Furthermore, they discuss the future of slowing progression of CKD as well as shifting kidney replacement therapies from the default in-center hemodialysis to home dialysis and transplantation. Join us as we regenerate excitement for the future in advocacy. Our guests include: Miriam Godwin, the NKF Health Policy Director Sharon Moe, Professor of Medicine in the Division of Nephrology and Hypertension at Indiana University and a Past President of the ASN Bruce Robinson, Professor of Medicine at the University of Michigan and the Arbor Research Collaborative for Health Dan Weiner, Associate Professor of Medicine at Tufts University School of Medicine and Editor-in-Chief of Kidney Medicine. Dan is a familiar friend of AJKD, having also served as Deputy Editor for ten years, and then as Policy Forum Editor for another five years. Resources Policy Forum collectionUSRDSKidneyXNKF Advocacy BlogAJKD 40th Anniversary Celebration

Welcome to another episode celebrating the 40th year of the American Journal of Kidney Diseases. This episode will focus on AJKD’s education features. We are joined by Dr. Jeff Berns, the Deputy Editor of AJKD, Professor of Medicine at the University of Pennsylvania and a Past President of the National Kidney Foundation, Dr. Agnes Fogo, Editor of the Atlas of Renal Pathology and Professor of Medicine at Vanderbilt University, Dr Ashgar Rastegar, Core Curriculum Editor, and Professor of Medicine and Global Health at Yale University, and Dr. Debbie Chen, former AJKD Editorial Intern and a research fellow at the University of California at San Francisco. Our guests discuss how AJKD provides education to the nephrology workforce including those who are in training. These educational tools include the Atlas of Renal Pathology, the Core Curriculum, AJKD quizzes and blog, NephMadness and the AJKD Editorial Internship. Finally, they wrap up by sharing their favorite classic paper from AJKD, which are all linked at the bottom of this episode’s description. Resources and links: Atlas of Renal PathologyCore CurriculumReviewsQuizzesAJKDBlog.orgEditorial InternshipNKF Professional Membership Our guest’s favorite articles: Pathologic Classification of Focal Segmental Glomerulosclerosis: A Working Proposal (2004)Clinical Epidemiology of Cardiovascular Disease in Chronic Renal Disease (1998)Management of Acute Kidney Injury: Core Curriculum 2018Principles of Kidney Pharmacotherapy for the Nephrologist: Core Curriculum 2021

This podcast will celebrate the 20th anniversary of the very first clinical practice guideline for CKD which included recommendations for CKD classification and staging. We are joined by Dr. Kerry Willis, Chief Scientific Officer of the NKF, Dr. Andy Levey Professor of Medicine at Tufts Medical Center and Joe Coresh, Professor of Epidemiology at Johns Hopkins School of Public Health and Mike Rocco, Chair of KDOQI and Professor of Medicine at Wake Forest Medical Center. The original workgroup for the CKD guideline published in 2002 in AJKD was chaired by Dr. Andy Levey and Dr. Coresh from Johns Hopkins for the adult section of the guideline and by Dr. Rob Portman for the Pediatric portion. This guideline had a profound impact on the clinical care of both adults and children with kidney disease and it also was a major catalyst for CKD research. The published guideline was cited by 3,500 journal articles and now has over 20 accompanying editorials. In 2012, the guideline was updated by the KDIGO and the classification stage was altered to include information on urine albumin excretion. But overall, the CKD staging system basically remains and in this podcast, we talk about how the guideline influenced clinical care, research and even policy.

On this episode, our guests discuss how AJKD has pursued and met objectives over the past 40 years. Specifically, we will discuss how the AJKD has not only influenced the care of patients with kidney disease but helped NKF support its mission. We will discuss how AJKD helped to shape kidney disease research and clinical care and help grow patient centered care. We are joined by four outstanding colleagues and speakers who will share their thoughts and experiences with AJKD and its impact on clinical care, research, education, and policy. Guests: Other 40th Anniversary materials: AJKD at 40: The Boston Era—Years 25-35 (2007-2016)Celebrating 4 Decades of AJKD40th Anniversary Special Collection: CKD40th Anniversary Special Collection: Kidney TransplantationJuly 2021 Table of ContentsJuly 1981 Table of ContentsKDOQI GuidelinesA Unifying Approach for GFR Estimation: Recommendations of the NKF-ASN Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Disease

Over the past year and a half, the NKF and ASN have been leading the effort to develop race-free eGFR test results while maintaining the accuracy of the test. The NKF-ASN Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Diseases has recently released its final report that recommends a new, race-free approach to estimate eGFR. In this collaborative episode with the ASN, the Task Force discusses how they approached the work and what efforts are being made to ensure the new equation is implemented as quickly as possible. Our guests, Dr. Cynthia Delgado, Dr. Lesley Inker, Dr. Joe Vassalotti and Tod Ibrahim discuss the goals of the Task Force and how the healthcare team came together to come up with a solution that better served kidney patients. They discuss the implications for patients, how clinicians and researchers can adopt these new guidelines, and what resources are available for both patients and the medical community to learn more. Developed in accordance with the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) and recommended by the National Kidney Foundation and American Society of Nephrology Task Force Reassessing the Inclusion of Race in Diagnosing Kidney Diseases, the new app is available for free by visiting the NKF website. If you enjoyed this episode, please follow us on Apple Podcasts, Spotify, Podbean or wherever you listen to your podcasts. Have ideas for future episodes? Email us at nkfpodcast@kidney.org or tweet us @NKF_Nephpros. Thank you for tuning in!