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The Poison Lab

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Dive into the captivating world of poisons with The Poison Lab! Hosted by Clinical Toxicologist Ryan Feldman (@EMPoisonPharmD), who has over a decade of managing poisoning and drug overdose via poison centers and in the emergency department. Also occasional co-hosted by his robo cohost Toxo! (@LabPoison). This show unpacks the fascinating history, cutting-edge science, and life-saving medical management of toxins from around the globe. From stories of those impacted to expert insights from pioneers in poisoning treatment, each episode brings you closer to understanding the poisons that lurk in plain sight. Explore episodes, med videos, games, and more at thepoisonlab.com—every poison has a story to tell!

Location:

United States

Description:

Dive into the captivating world of poisons with The Poison Lab! Hosted by Clinical Toxicologist Ryan Feldman (@EMPoisonPharmD), who has over a decade of managing poisoning and drug overdose via poison centers and in the emergency department. Also occasional co-hosted by his robo cohost Toxo! (@LabPoison). This show unpacks the fascinating history, cutting-edge science, and life-saving medical management of toxins from around the globe. From stories of those impacted to expert insights from pioneers in poisoning treatment, each episode brings you closer to understanding the poisons that lurk in plain sight. Explore episodes, med videos, games, and more at thepoisonlab.com—every poison has a story to tell!

Twitter:

@labpoison

Language:

English

Contact:

2628449646


Episodes
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If I had a Nickel (Mystery Case) & Toxicologist vs The internet (#13) with Dr. Damilola Idowu-Ellsworth

2/11/2026
In this episode of The Poison Lab, host Ryan Feldman is joined by medical toxicologist Damilola Idowu‑Ellsworth for a fast-moving, case-heavy conversation packed with clinical pearls, listener participation, and classic toxicology weirdness. The show opens with listener guesses for the previously released mystery case before diving headfirst into a rapid-fire series of Stump the Toxicologist cases—questions pulled straight from the internet and real-world toxicology problem-solving. Along the way, Ryan and Dami cover everything from rodenticides and drug-testing myths to how to clean a benzodiazepine bottle, plus one of the most toxic substances you’ve probably never heard of. One lucky listener also wins a copy of Poisonous Fungus Amongus, and a shout-out to the newly released second edition featuring photography from expert mycologists. Skip the listener guesses and jump straight to the mystery toxin: 38:15 The rest of the episode is Dr. Idowu and Ryan discuss the topics below. Looking for timestamps? Join the supporting member feed! Stump the Toxicologist – Case Discussions (Looking for timestamps? Join the supporting member feed!) Case #1 methemoglobinemia, renal failure inducing enema Case #2 Wide-complex dysrhythmia from an over-the-counter topicalPaper from Ryan on the topical toxicity (or lack there of) of this product Case #3 Case #4 GCS 15 and normal vitals… until they’re notPaper from Ryan on this tricky toxic time bomb Internet & Listener Questions Support the show Review the show where ever your listening Get Messages from Toxo (Join the Newsletter!) Join as a supporting member

Duration:01:40:54

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Poison Lab Update: Mushroom Poisoning Radio Roundup

2/4/2026
Hey everybody, you’re listening to The Poison Lab—well, almost. We’ve got a new episode coming next week, but we’re running a little behind on our usual release schedule because… life happens. That said, if you’re looking for some toxicology content right now, I’ve got you covered. Recently, I had the chance to appear on two local and state radio shows talking about one of my favorite topics: mushroom poisoning 🍄—and both were an absolute blast. 🌱 Garden Talk (Call-In Episode) (Ryan starts @ 1 hour and 14 min) The first appearance was on Garden Talk, a fun, live call-in show where we covered: GOTTA PICCEMPoisonous Fungus Among Us It was lively, unpredictable, and a great example of how curious people are about mushrooms once you open the door. 📻 Local Health Update Radio Segment After that, I joined a local radio health update to talk specifically about mushroom poisoning from a public-health perspective. It’s always interesting to hear how radio hosts approach such a niche topic—and how quickly it turns into something broadly relevant. 🔬 Want a Quick Toxicology Fix? If you’re itching for some Poison Lab content while you wait for the next full episode, these two appearances are a great place to start. And don’t worry—we’ll be back next week with a full episode and answers to our mystery case. Thanks, as always, for listening. Hope to see you there. — Ryan

Duration:00:01:36

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Sick at Work? A Poisonous Cause of Coworker Illness?

12/18/2025
Do you think you know the cause of these symptoms? Send your guesses to toxtalk1@gmail.com to take part in the next episode Support the show Review the show where ever your listening Get Messages from Toxo (Join the Newsletter!) Join as a supporting member The GOTTA PICCEM Poisonous Mushroom Game! The Poisonus Fungus Amongus Children's Book! Full book reading (6 minutes!) Tox trinkets (Rep the show at home!) Reach the show More Show Resources Ryan's Medical Games and ResourcesShow Website

Duration:00:01:55

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Outbreak: Thebaine Poisoning from Poppy Seed Tea in Australia

12/3/2025
In November 2022, hospitals across Australia began seeing patients with sudden rigidity, spasms, seizures—and in some cases cardiac arrest—after drinking homemade poppy seed tea. The source? Food-shelf poppy seeds contaminated with extraordinarily high levels of thebaine, an opioid alkaloid that acts nothing like morphine. In this Outbreak episode, host Ryan Feldman, clinical toxicologist and emergency medicine pharmacist, investigates how pharmaceutical-grade, thebaine-rich poppy seeds were mistakenly repackaged into the food supply—and how poison centers, clinicians, labs, and public health teams traced and contained the threat within days. You’ll hear firsthand from the experts who responded: Together, they walk us through the outbreak timeline—from the first ICU cases and puzzling “strych­nine-like” neuroexcitation to the multi-state investigation, product recall, and lessons for future foodborne poisonings. Looking for timestamps? A fully timestamped version—so you can jump to any topic—is available to our supporting members. 💡 Key topics: 📍 Resources & Mentions: case series on thebaine-contaminated poppy seeds (Queensland Health, NSW Health)Dr. Roberts led kinetics study on thebainePoison LabMarkham Aconite Poisoning 🎧 Listen now: www.ThePoisonLab.com 💬 Have thoughts or questions? Instagram @tox_talk • Twitter @LabPoison • Email toxtalk1@gmail.com Disclaimer: The Poison Lab is for educational purposes only and does not provide medical advice. If you suspect a poisoning, contact your local poison center. In the U.S., call 1-800-222-1222. Support the show Review the show where ever your listening Get Messages from Toxo (Join the Newsletter!) Join as a supporting member The GOTTA PICCEM Poisonous Mushroom Game! The Poisonus Fungus Amongus...

Duration:01:17:13

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Poisonous Fungus Amongus is Here— The Rhyming Kid (or Adult) Book For Mushroom Safety

11/17/2025
Get your copy here! https://a.co/d/8QUBmQy Want to hear it with insights from the author?: • Poisonous Fungus Among Us | Full Children’... Don't have time for the full thing: check the highlights: • Poisonous Fungus Amongus Highlights Reel Want a clearer picture: Full reading large scale here: • Poisonous Fungus Amongus- Children's Book ... From the mind of a toxicologist who treats real mushroom poisonings alongside doctors and poison centers comes Poisonous Fungus Amongus—a playful, rhyming adventure into the fascinating world of poisonous mushrooms! Inside, readers will find a colorful introduction to mushroom anatomy and ecology—learning the parts of a mushroom and discovering helpful hints for safe foraging and identifying dangerous look-alikes. Every species featured in these pages is a real poisonous mushroom, brought to life through vivid illustrations and engaging verse. This beautifully illustrated book goes beyond the basics, exploring how mushrooms grow, reproduce, and take shape in nature—from tiny spores to sprawling mycelium to the fruiting bodies we find in forests and fields. Through rhymes and clear explanations, readers learn to recognize essential mushroom features—caps, gills, pores, rings, bulbs (volvas), veils, warts, scales, spore prints, and gill types like free, adnate, and decurrent. Each detail helps distinguish the edible from the toxic—and shows how some features can fool us! The story encourages safe and curious observation: note each feature, dig gently to look for bulbs, observe nearby trees and seasons, and check for bruising or color changes. Along the way, readers also discover fungi’s hidden ecological roles, from tree-nurturing mycorrhizae to the saprotrophs that recycle the forest floor. With rhythm, rhyme, and a spark of scientific wonder, Poisonous Fungus Amongus blends accuracy with imagination—inviting kids and adults alike to explore and respect the natural world, while learning that curiosity and caution must always grow together when it comes to mushrooms. Perfect for young readers, nature lovers, teachers, and families who want to explore the mysterious and magical world of fungi! Support the show Review the show where ever your listening Get Messages from Toxo (Join the Newsletter!) Join as a supporting member The GOTTA PICCEM Poisonous Mushroom Game! The Poisonus Fungus Amongus Children's Book! Full book reading (6...

Duration:00:03:17

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LIVE from Chicago: 2025 NACCT Research Review – Insights from the North American Congress of Clinical Toxicology

10/5/2025
Show Notes In this special live episode from the 2025 North American Congress of Clinical Toxicology (NACCT), Ryan takes you inside the conference to hear directly from the researchers themselves. Covering 11 abstracts that span high-stakes management decisions, surprising case reports, and challenges to toxicology dogma, this year’s highlights feature everything from amlodipine overdoses to naturopathic misadventures, metformin-associated blindness, and more. The show kicks off with a foreword from Ryan and Dr. Jon Cole (abstract co-chair for AACT) discussing some of their favorite research from the conference. If you couldn’t make it to NACCT or just want to catch up on some of the most impactful new research in our field, this episode will give you a front-row seat. Check below for links to the published abstracts, the full list of studies discussed, and timestamps for where you can hear each one. Link to published abstract manuscript Foreword with Dr. Jon Cole 10:24 #7. Is beta blocker toxicity associated with hypoglycemia? 17:58 #237. V-A ECMO as a treatment for vasoplegic shock in amlodipine poisoning: a comparison 27:59 #247. Blocked but not beaten: ECMO’s role in severe amlodipine toxicity – a poison center case series 28:39 #26. Amlodipine double-dose therapeutic errors reported to Poison Centers 30:19 #27. Dosing on the edge: unpacking inadvertent amlodipine ingestions reported to a single poison center 33:44 #292. Intravenous administration of sodium zirconium cyclosilicate resulting in death Researcher interviews 43:57 – #21. Quantitative analysis of amlodipine removal by plasmapheresis 48:14 – #23. Relationship between reported ingestion dose and outcome in amlodipine poisoning 51:18 – #24. Management of severe amlodipine toxicity with high-dose calcium alone 56:37 – #70. Iatrogenic exposure to long-acting buprenorphine injectable in an opioid-naïve patient 59:52– #182. Left in the dark: a case of blindness in the setting of metformin toxicity 61:52 – #169. Just because it’s natural doesn’t mean it’s safe: a case of pediatric toxicity from topical and herbal remedies 64:12 – #203. Serotonin syndrome after vaping Moocah 66:47 – #307. Intravenous ozone autohemotherapy: a retrospective observational case series 71:06 – #134. Do they really need n-acetylcysteine? Exploratory analysis of outcomes in patients with elevated liver function tests but no detectable acetaminophen 75:14 – #130. Outcomes of acute acetaminophen-poisoned patients treated with and without fomepizole: a Toxic registry study

Duration:01:41:29

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LIVE from Chicago: 2025 NACCT Research Review – Insights from the North American Congress of Clinical Toxicology

9/17/2025
Show Notes In this special live episode from the 2025 North American Congress of Clinical Toxicology (NACCT), Ryan takes you inside the poster hall to hear directly from the researchers themselves. Covering 11 abstracts that span high-stakes management decisions, surprising case reports, and challenges to toxicology dogma, this year’s highlights feature everything from amlodipine overdoses to naturopathic misadventures, metformin-associated blindness, and more. If you couldn’t make it to NACCT or just want to catch up on some of the most impactful new research in our field, this episode will give you a front-row seat. Check below for links to the published abstracts, the full list of studies discussed, and timestamps for where you can hear each one. Link to published abstract manuscript Preamble with Dr. Jon Cole 09:20 - Abstract #7. Is beta blocker toxicity associated with hypoglycemia? 17:00 - Abstract #237. V-A ECMO as a treatment for vasoplegic shock in amlodipine poisoning: a comparison 26:50 - Abstract #247. Blocked but not beaten: ECMO’s role in severe amlodipine toxicity – a poison center case series? 28:15 Abstract #27. Amlodipine double-dose therapeutic errors reported to Poison Centers 29:00 Abstract #27. Dosing on the edge: unpacking inadvertent amlodipine ingestions reported to a single poison center 32:38 - 292. Intravenous administration of sodium zirconium cyclosilicate resulting in death Abstracts & Guests 40:06 – Abstract #21. Quantitative analysis of amlodipine removal by plasmapheresis 44:00 – Abstract #23. Relationship between reported ingestion dose and outcome in amlodipine poisoning 47:30 – Abstract #24. Management of severe amlodipine toxicity with high-dose calcium alone 53:00 – Abstract #70. Iatrogenic exposure to long-acting buprenorphine injectable in an opioid-naïve patient 55:51 – Abstract #182. Left in the dark: a case of blindness in the setting of metformin toxicity 57:56 – Abstract #169. Just because it’s natural doesn’t mean it’s safe: a case of pediatric toxicity from topical and herbal remedies 59:57 – Abstract #203. Serotonin syndrome after vaping "Moocah" 1:03:00 – Abstract #307. Intravenous ozone autohemotherapy: a retrospective observational case series 1:05:59 – Abstract #134. Do they really need n-acetylcysteine? Exploratory analysis of outcomes in patients with elevated liver function tests but no detectable acetaminophen 1:09:30 – Abstract #130. Outcomes of acute acetaminophen-poisoned patients treated with and without fomepizole: a Toxic registry study 1:15:30 – Abstract #295. Evaluation of onset and resolution...

Duration:01:40:37

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Toxicologist vs The internet (#12) with Dr. Joe Kennedy MD

9/10/2025
In this episode of The Poison Lab, host Ryan Feldman is joined by Dr. Joe Kennedy, medical toxicologist at the University of Vermont and consultant for the Northern New England Poison Center. Together they work through real poisoning cases to sharpen toxic differentials, sum up practical resuscitation priorities, and connect first-principles pharmacology to bedside decisions. They also answer listener questions on THAM vs bicarbonate, when to dialyze even with “normal” kidneys, and why rattlesnake antivenom costs so much—plus the real-world logistics of sourcing exotic antivenoms in the U.S. Dr. Kennedy and Ryan discuss the topics below. Looking for timestamps? Join the subscribed feed! Recent outbreak of deaths as related to case 4 Want the cases summarized and sent to you so you can come up with your differential before the show? SIGN UP FOR THE NEWS LETTER! Listener Q&A Call outs from the show NACCT Abstracts!Clover coagulopathy!THAM VS BICARB ElectrolytesRyanArticle on snake antivenom costing >200,000 for one patientArticle on exotic antivenom procurementCase report Ryan published on treating blue Indonesian pit viper Support the show Review the show where ever your listening Get Messages from Toxo (Join the Newsletter!) Join as a supporting member The GOTTA PICCEM Poisonous Mushroom Game! Tox trinkets (Rep the show at home!) Reach the show More Show Resources Ryan's Medical Games and Resources

Duration:01:34:49

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GOTTA PICCEM is Here! — The Poisonous Mushroom Card Game Launch

9/3/2025
GOTTA PICCEM: The Poisonous Mushroom Card Game 👉 Order now right here OR go to www.gottapiccem.com and click "Buy GOTTA PICCEM" Why this is awesome What started as a nerdy teaching tool made to teach mushroom poisoning by folks who treat mushroom poisoning is now a full-fledged card game—equally great for Friday game night and the classroom. What’s inside the deck 58 Poisonous Mushroom Cards88 Play Cards + 30 Bonus CardsToxin-Based ScoringEndless Replayabilitygottapiccem.com Learn while you play Dive into the companion blog at www.gottapiccem.com for: 📖 Start here: gottapiccem.com (Companion Blog → “Learn the Mushrooms”) How to get it 👉 Order now right here OR go to www.gottapiccem.com and click "Buy GOTTA PICCEM" South KoreaGlobal availability P.S. We’re exploring U.S. manufacturing to lower costs and expand distribution—timeline TBD—so we made the game available now. Join the fun If you grab a copy: 📸 Snap a photo of your first round ✉️ Send it to toxtalk1@gmail.com or tag @LabPoison / @tox_talk Nothing would make Ryan happier than seeing the community play!

Duration:00:03:21

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Ryan is LIVE on the Radio Thursday July 17th 11:45AM-12:30 PM CST WPR Larry Meiller Show!

7/16/2025
Listen here (https://www.wpr.org/shows/larry-meiller-show) to hear Ryan Live on AIR for the Larry Meiller show, Thursday July 17th 11:45AM-12:30 PM CST. Check this "Listen Live" link if your having trouble!

Duration:00:00:54

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Poisoning Outbreak: Aconite Poisoning at Markham, Ontario Restaurant

7/10/2025
Support the show Review the show where ever your listening Join as a supporting member The GOTTA PICCEM Poisonous Mushroom Game Landing Page! Tox trinkets (Rep the show at home!) Reach the show More Show Resources Get Messages from Toxo (Newsletter)Ryan's Medical Games and ResourcesShow Website The Poison Lab: Outbreak – Markham Aconite Poisoning On August 29, 2022, twelve diners at a Markham, Ontario restaurant fell critically ill with vomiting, numbness, and life-threatening arrhythmias. The culprit? A deadly plant toxin: aconite. In this episode—the first of a new Poison Lab Outbreak series—we go inside the Markham mass poisoning case. Join host Ryan Feldman, clinical toxicologist and emergency medicine pharmacist, as he investigates how a rare and lethal toxin ended up in a restaurant spice jar and nearly cost lives. You’ll hear firsthand from the experts who responded to the outbreak: Together, they walk us through the outbreak timeline—from the first patients in VT to the public health investigation that uncovered a mislabeled spice bag full of pure aconite root. Looking for timestamps? A fully timestamped version of the episode—so you can jump to any topic—is available to our supporting members. 💡 Key topics: galangal 📍 Resources & Mentions: Case series about the incident written by Dr. Kent, Sathya, and ThompsonTwitter/XThe Poison Lab previous aconite episode: Open and shut (Mystery Case #31)Paper written by Ryan, Dan McCabe, and Crissy Lawson 🎧...

Duration:01:15:26

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A Mnemonic Poisonous Mushrooms and Their Effects- GOTTA PPICEM

4/30/2025
Support the show Review the show where ever your listening Join as a donating member The GOTTA PICCEM Poisonous Mushroom Game Landing Page! Tox trinkets (Rep the show at home!) Reach the show More Show Resources Get Messages from Toxo (Newsletter)Ryan's Medical Games and ResourcesShow Website If you are looking for links to Dr. Basset's initiatives check back later, they are not fully launched yet! Check it out on Dr. Hamilton's website as well Poison Mushrooms! Got’a Pic’em (GOTAAPPICEM) A mnemonic device to sort through mushroom ingestions – The Hot Stove League of EM/Tox The GOTAA PPICCEM Mnemonic Late-Onset (Severe) Toxic Mushrooms ("GOTA") These mushrooms have delayed symptoms (>6 hours) and are associated with significant toxicity: G – Gyromitrin (Gyromitra esculenta) – False morels; inhibits GABA, leading to seizures. O – Orellanine (Cortinarius spp.) – Causes renal failure; famously poisoned The Horse Whisperer author. T – Tricholoma equestre (Man on Horseback) – Leads to rhabdomyolysis. A – Amatoxin (Amanita phalloides, Galerina spp.) – Causes liver failure; the most lethal mushroom toxicity. Early Onset Nausea, Late Toxicity Mushrooms ("A²P²") A² – Allenic norleucine (Amanita smithiana) – Found in the Pacific Northwest; early GI symptoms followed by renal failure. These may present early but still cause significant toxicity. P² – Paxillus spp. – Can cause hemolytic anemia and multi-organ injury. Early-Onset Nausea Mushrooms ("PICCEM") P– Psilocybin (Psilocybe spp.) – Hallucinogenic, similar to LSD, typically low toxicity but may cause hyperthermia or seizures. Symptoms appear within 6 hours and are usually self-limited. I – Ibotenic Acid & Muscimol (Amanita muscaria, Amanita pantherina) – Acts like a “mushroom speedball”, causing both stimulant and sedative effects. C – Coprine (Coprinus spp., Inky Caps) – Induces disulfiram-like reaction with alcohol. E – Emetic Mushrooms (LBMs: Little Brown Mushrooms) – Various species that cause self-limited vomiting and diarrhea. M – Muscarine...

Duration:00:22:31

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MURDER for Lunch: Toxicologist vs The internet (#11) with Dr. Amy Zosel MD

4/30/2025
In this episode of The Poison Lab, host Ryan Feldman is joined by Dr. Amy Zosel, a medical toxicologist, emergency physician, and educator. Together, they use real poisoning cases to practice identifying toxins and flexing their toxic differential The conversation dives into intriguing and challenging toxicology cases, with a focus on educating listeners about real-world poisoning scenarios, myth-busting internet misinformation, and providing practical clinical insights. Mini episode with Dr. Robert Bassett on Remembering Poisonous Mushrooms Dr. Zosel and Ryan discuss: 14:15 Case 1 33:04 Case 2 News story 37:00 Case 3 New story 48:00 Case 4 News storyUS outbreak "Robocough" Study about Naloxone in Clonidine overdose ++Spoiler++: Below this will be key takeaways regarding managing the poisonings discussed, it may ruin your experience if you are guessing the poisons Key Takeaways: Amatoxin Mushroom PoisoningTetramine Toxicity A Lethal mushroom hiding in edible mushrooms Mushroom foraging danger Resources Mentioned: 1-800-222-12221-800-273-82551-800-662-HELP (4357) Follow The Poison Lab: Twitter@LabPoisonInstagram@tox_talkWebsitewww.ThePoisonLab.com Subscribe and Review: Love what you're hearing? Help us reach more toxicology enthusiasts by leaving a review on Apple Podcasts, Spotify, or wherever you listen. Don’t forget to share this episode with...

Duration:01:30:29

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Leafy Greens & Injured Beans: Natures Nephrotoxins – A Poison Lab & NephMadness Collaboration

3/1/2025
In this special collaboration with NephMadness, we're diving into the world of nephrotoxins with an expert panel from Virginia Commonwealth University. NephMadness is an educational competition modeled after March Madness, and this year, one of the featured regions focuses on plant-based nephrotoxins. Together, with our expert panel we break down the competing nephrotoxin teams: Tubular Toxins vs. Oxalate Offenders. Joining us are Dr. Anna Vinnokova (Nephrologist), Dr. Rachel Khan PharmD (Neph pharmacist), Dr. Ethan Downes (Nephrology fellow), and the legendary nephrotoxicologist, Dr. Josh King (Board certified Nephrologist and Toxicologist). We ALMOST named this episode "Getting Downe with the Mad Neph King and the Bean Queens"... but we didn't, your welcome. After the show, go to the blog and vote for your favorite! Expect irreverent musings, deep dives into toxic plant exposures, and a mystery case reveal that will leave you questioning your diet. Topics and Timeline of Episode: Intro Listener Guesses With Josh and Ryan– 8:30 Listener Winner – 25:42 NephMadness and Guest Introductions – 28:07 Toxin Reveal – 33:41 NEJM Case report Tubular Toxins – 35:46 Aristolochic Acid & the Belgian Weight-Loss Clinic Outbreak – Black Licorice & Its Surprising Toxic Effects The Oxalate Offenders Team: How Dietary Oxalates Harm the Kidneys – 52:00 Historical ContextHalogeton glomeratusOxalate in PlantsImpact on the BodyChronic inflammation from excess oxalate deposition leads to CKD progressionHigh-Oxalate FoodsEverything in moderation! Practical Advice for Clinicians & Patients on Herbal Medicine Use – 1:00:00 Herbals may not all be safe: Josh King Discovering Contaminants– 1:01:11 Wrap up– 1:08 Key Takeaways: Aristolochic acidBlack licorice toxicity

Duration:01:16:40

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A Mysterious Case of Weakness, Low Potassium, and Kidney Injury

2/12/2025
Do you think you know the cause of these symptoms? Send your guesses to toxtalk1@gmail.com to take part in the next episode Support the show!Rep the show!Show website

Duration:00:01:55

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Should we Give Naloxone in Cardiac Arrest? Insights From the Authors of Three Key Studies

1/6/2025
Finally, the journal club to rule ALL journal clubs. In this episode of The Poison Lab, we tackle one of the biggest topics in emergency medicine and toxicology: Should naloxone be given during opioid-associated cardiac arrest? With three fantastic studies published in 2024, we’re diving into the data and hearing directly from the authors themselves. Join host Ryan Feldman as he interviews Dr. Eric Quinn, Dr. Joshua Lupton, and Dr. David Dillon, some of the minds behind the latest research exploring the role of naloxone in out-of-hospital cardiac arrest (OHCA). With perspectives ranging from clinical outcomes to practical implementation, this episode offers a deep dive into what these studies tell us—and what remains unanswered. But that’s not all! Featuring special guests Spencer Oliver and Chris Pfingston from EMS 2020, this roundtable discussion incorporates the real-world insights of prehospital EMS professionals who face these decisions every day. Together, the panel unpacks: Whether you’re a toxicologist, EMS professional, or just curious about the intersection of drugs, overdose, and resuscitation, this episode is packed with actionable insights, expert opinions, and engaging discussions. Tune in now to explore the science, controversy, and future directions for naloxone in cardiac arrest care! Studies discussed in the show Outcomes of Out-of-Hospital Cardiac Arrest Patients Who Receive Naloxone in an EMS System with a High Prevalence of Opioid Overdose Association of Early Naloxone Use with Outcomes in Nonshockable Out-of-Hospital Cardiac Arrest Naloxone and Patient Outcomes in Out-of-Hospital Cardiac Arrest in Northern California Studies and guidelines mentioned Editorial by Dr. Lavonas on Dr. Lupton's study AHA 2023 GuidelinesAHA 2021 Position statement on opioid overdose out of hospital cardiac arrestStudy of opioid overdose death after bystander naloxone training mentioned by Toxo Shows mentioned Chris and Spencer's excellent EMS showRyan's Interview on Poisoning Cardiac Arrest GuidelinesJournal club with Ryan and Dr. Dillon Timestamps and chapters Introduction (0:00–12:25) Podcast

Duration:01:17:42

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The Poison Lab Holiday Bonus- Stump The Toxicologist Reel 2022

12/25/2024
In this special holiday bonus episode, Ryan takes a look back at some of the most captivating episodes of The Poison Lab from 2022. Get ready for an ultimate test of your toxicology differential diagnosis skills as we compile all the "Stump the Toxicologist" segments into one streamlined, binge-worthy episode. Explore eight unique poisoning cases, be sure to check the show notes for a description of each case. time stamp of where it begins, and links to the original episodes, where you can dive deeper into the discussions and unravel the mysteries behind these intriguing cases! Case Teasers and Time Stamps Episode 13, March 2nd, 2022: Dr. Howard Greller Case 1:Case 2:Case 3:Case 4: Episode 15, July 6th, 2022: Dr. Josh Trebach Case 1:Case 2:Case 3:Case 4: Episode 17, November 9th, 2022: Dr. Emily Kieran Case 1:

Duration:02:05:43

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The Forever Chemicals Inside You and Your Environment with the Wizard of PFAS Dr. John Downs

11/27/2024
Join host Ryan Feldman in an insightful episode of "The Poison Lab" as he sits down with Dr. John Downs, Director of the Virginia Poison Center, and one of the leading experts on per- and polyfluoroalkyl substances (PFAS), commonly known as "forever chemicals." Known for their persistence in the environment and human body, PFAS have raised significant public health concerns over the past few decades. Dr. Downs shares his journey through occupational medicine, toxicology, and public health, which uniquely positioned him to provide expertise on PFAS exposure, health risks, and ongoing regulatory efforts. Together, they delve into the origins, uses, and potential health effects of these ubiquitous compounds, while examining government policies, environmental impact, and strategies to reduce exposure. A must-listen for anyone interested in the intersection of environmental health and toxicology! Episode Breakdown: 2:428:0115:4120:4225:2031:1541:1445:29 Key Topics Discussed 2:42 – What Are Forever Chemicals? PFOA (perfluorooctanoic acid)PFOS (perfluorooctanoic sulfonic acid)thousands of different PFAS compounds 8:01 – History of PFAS and Associated Health Concerns PFAS in the Environment Non-stick cookware:Firefighting foam:Fast food wrappers and other consumer products:Biosolids:Ski wax:

Duration:01:16:54

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Episode 2 Teaser

6/7/2020
Can you figure out what is causing these symptoms? Send guesses to Toxtalk1@gmail.com

Duration:00:00:59

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Teaser- Episode 1

5/26/2020
Can you figure out what poison Ryan and Toxo will be talking about in episode 1? Tune in, first episode 5/27

Duration:00:01:01