BrainStorm: Decoding Depression Podcast

In this episode of BrainStorm: Decoding Depression, guide Harmony Hilton engages in a powerful conversation with Dr. Madhukar Trivedi, Director of the Center for Depression Research and Clinical Care at UT Southwestern, and criminal defense attorney and mental health advocate Terry Bentley Hill. The trio delves into the intersection of law, women's mental health, and youth mental health, exploring personal experiences, the language of depression, and the critical need for early intervention.

In this episode of BrainStorm: Decoding Depression, Dr. Madhukar Trivedi, director of the Center for Depression Research and Clinical Care at UT Southwestern, is joined by Nicole Small, Lyda Hill Philanthropies CEO, and Season 3 host, Harmony Hilton, as they discuss how philanthropy and women's mental health intersect as well as how the community can best invest in mental health to support and empower women and youth.

Dr. Madhukar Trivedi, the Director of the Center for Depression Research and Clinical Care at UT Southwestern, and Dr. Samantha Meltzer-Brody, the Director of the University of North Carolina Center for Women’s Mood Disorders and the Assad Meymandi Distinguished Professor and Chair discuss the importance of women’s mental health with the connection to youth and the entire family with Season 3 host, Harmony Hilton. Season 3 of BrainStorm: Decoding Depression focuses on “Celebrating Women Who Tell Our Mental Health Story”. This first episode narrows in on women and policy that affects women and youth mental health as well as the research and projects pertaining to improving the mental health landscape. Follow us on Podbean: utswcdrc.podbean.com Contact us at: DecodingDepressionPodcast@UTSouthwestern.edu Learn more about the CDRC: www.utsouthwestern.edu/labs/trivedi www.utsouthwestern.edu/cdrc

Today’s episode, hosted by Erin A. Harper, PhD, NCSP is all about resilience. Are you born with it? Can it be taught? Listen in as Dr. Madhukar Trivedi and special guests Tobi Fuller, PhD and Adrienne Mays, MEd take a deep dive into this topic. Adrienne Mays serves in the capacity of Learning Supervisor at the CDRC, supporting our Blue Steel program. An advocate for student equity and excellence, her accomplishments include recognition as Dallas ISD Campus Teacher of the Year and TEA Exemplary Teacher Designation. She obtained her M.Ed. in Educational Leadership from Southern Methodist University. Tobi Fuller is an educator, registered nurse, and program developer with over 18 years of experience working with youth and extensive experience in designing, developing, and instructing programs for various learner types and levels. Tobi serves as Instructional Design Specialist at the CDRC, supporting our Youth Aware of Mental Health (YAM) program. Follow us on podbean: utswcdrc.podbean.com Contact us at DecodingDepressionPodcast@UTSouthwestern.edu Learn more about the CDRC: www.utsouthwestern.edu/labs/trivedi www.utsouthwestern.edu/cdrc

Kathryn Forbes interviews Dr. Madhukar Trivedi and special guests Dr. Tracey Brown and Dr. Early Denison about the state of youth in Dallas, Texas. Dr. Tracey Brown serves as the Executive Director of Mental Health Services in Dallas Independent School District. A licensed professional counselor who specializes in resiliency and overcoming trauma and grief, she has served in the field of counseling, education, and mental health for more than 28 years, working with thousands of children and families to help them overcome huge obstacles in their life and relationships. Dr. Brown holds a Bachelor of Arts degree in psychology from the University of North Texas, a Master of Arts degree in counseling and certification in professional school counseling from Dallas Baptist University, and a Ph.D. degree in psychology from Walden University. She serves as an adjunct professor at Dallas Baptist University in the School of Education, and is an award-winning author, speaker, and talk show host. To learn more, visit www.dallasisd.org/mentalhealth. Dr. Early Denison is a pediatrician in the Dallas area and partner in his medical practice. He’s a proud Texas A&M Aggie and received his MD from the University of Texas Southwestern Medical School. He completed his pediatric internship and residency at Children’s Medical Center, and he has an MBA with a healthcare focus. He co-hosts his own podcast, Parenting for the Present, sharing best practices and up-to-date research for practical and proactive parenting. To learn more, visit www.parentingforthepresent.com. Follow us on podbean: utswcdrc.podbean.com Contact us at DecodingDepressionPodcast@UTSouthwestern.edu Learn more about the CDRC: www.utsouthwestern.edu/labs/trivedi www.utsouthwestern.edu/cdrc

Episode 7 features an insightful conversation between Dr. Madhukar Trivedi and Dr. Debra Atkisson about the state of youth in Fort Worth, Texas. What is research showing, and what are the pediatricians and psychologists from the largest clinics in Fort Worth seeing? Hosted by Kathryn Forbes. Debra Atkisson, MD is a board-certified child and adolescent psychiatrist who serves as the Regional Medical Director for Connections Wellness Group in the Dallas Fort Worth metroplex. As a Professional Certified Coach, she also serves as a Physician Development Coach at the TCU Burnett School of Medicine. She has served in leadership roles in Texas psychiatry, and currently is the President of the Texas Society of Child and Adolescent Psychiatry as well as a Representative to the American Psychiatric Association from Texas. A fifth-generation Texan, Dr. Atkisson graduated from Texas Tech University School of Medicine. She completed a general psychiatry residency and child and adolescent psychiatry fellowship at the Karl Menninger School of Psychiatry in Topeka. She is passionate about serving as an advocate for patients’ mental health as well as educating the public and fellow physicians about the many ways we can all help improve the mental health of our patients. For more information about Connections Wellness Group, visit their website: www.connectionswellnessgroup.com Follow us on podbean: utswcdrc.podbean.com Contact us at DecodingDepressionPodcast@UTSouthwestern.edu Learn more about the CDRC: www.utsouthwestern.edu/labs/trivedi www.utsouthwestern.edu/cdrc

This episode, hosted by Kathryn Forbes, features Marcellina Melvin, MA, LPC—the Deputy Director of The Hackett Center for Mental Health—in conversation with Dr. Madhukar Trivedi about health disparities among communities of color and the research and public policy initiatives that work to improve our mental health care system and advance health equity. The Hackett Center for Mental Health is a regional center of Meadows Mental Health Policy Institute. For more information, visit: thehackettcenter.org Follow us on podbean: utswcdrc.podbean.com Contact us at DecodingDepressionPodcast@UTSouthwestern.edu Learn more about the CDRC: www.utsouthwestern.edu/labs/trivedi www.utsouthwestern.edu/cdrc

What really IS depression? What does depression research entail? How does research work, who benefits from it, why is participation so important, and how can we progress it even further? If you’ve ever wondered how research studies are conducted, this episode is for you! Episode 5 features special guests Dr. Manish Jha, Dr. Geoffrey Obel, and Dr. DeWanda Harris Trimiar in discussion about research study protocols, diversity in participation, safety and privacy, and community research design. Dr. Manish Jha serves as Assistant Professor of Psychiatry in the CDRC, and has the endowed title of the O’Donnell Brain Institute Clinical Neuroscience Scholar. Dr. Jha is conducting clinical research that aims to identify the biological mechanisms of depression, anxiety and substance use disorders to inform the development of novel treatments. In addition to his research and educational activities, Dr. Jha maintains an active clinical practice focusing on evidence-based interventions for difficulty-to-treat depressive and anxiety disorders. Dr. Geoffrey Obel has been advancing research and knowledge in public health for over 10 years, working with organizations to develop policies, procedures and programs that facilitate improved public health outcomes. Now, he serves as a National Project Director for the Innovative Development Research Engagement Manual (I-DREM) at the University of Texas Southwestern Medical Center, working to increase recruitment and retention of diverse populations in Randomized Clinical Trials and Non-Experimental Studies. Dr. DeWanda Harris Trimiar has her bachelor’s in social work, a master’s in Human Service Counseling, and a PhD in Counseling & Psychological Studies with a concentration in Research. She currently serves as a Research Patient Navigator and Recruitment and Retention Specialist for the Texas Node of the National Institute of Drug Abuse’s Clinical Trials Network. Here, Dr. Trimiar helps identify areas of interest for clinical trials, acts as a liaison for participants, and serves as Program Director for the RMIST study, developing the protocol and aiding in understanding of the science supporting the research. Follow us on podbean: utswcdrc.podbean.com Contact us at DecodingDepressionPodcast@UTSouthwestern.edu Learn more about the CDRC: www.utsouthwestern.edu/labs/trivedi www.utsouthwestern.edu/cdrc

Kathryn Forbes interviews Dr. Madhukar Trivedi and special guest Tom Osborne, the co-founder and CEO of Shamiri Institute, about evidence-based youth interventions. This discussion includes topics such as contextual and cultural understanding of mental health approaches, the meaning of stigma, and the impact of peer support. The Shamiri Institute is a youth-led organization that provides affordable, evidence-based and personalized mental health care to young people across Sub-Saharan Africa. To learn more about the Shamiri Institute, visit their website www.shamiri.institute and check out Tom Osborne’s TED Talk. Follow us on podbean: utswcdrc.podbean.com Contact us at DecodingDepressionPodcast@UTSouthwestern.edu Learn more about the CDRC: www.utsouthwestern.edu/labs/trivedi www.utsouthwestern.edu/cdrc

Kathryn Forbes interviews Dr. Madhukar Trivedi and special guest Kelly Davis, Associate Vice President of Peer and Youth Advocacy at Mental Health America, about youth lived experiences, community networks, and research. Kelly opens up honestly about her own mental health journey, her experience navigating the mental healthcare landscape, and how this has all led to the amazing work she does today. Learn about the ways that we can advance mental health services and support for youth, in schools and beyond. Follow us on podbean: utswcdrc.podbean.com Contact us at DecodingDepressionPodcast@UTSouthwestern.edu Learn more about the CDRC: www.utsouthwestern.edu/labs/trivedi www.utsouthwestern.edu/cdrc

What is the difference between mental illness and mental health? How can we make the shift from being reactive to being proactive? How can we promote recovery of the whole person, rather than just treat the symptoms? In this episode, Kathryn Forbes interviews Dr. Madhukar Trivedi and Dr. Anne Fuller about strategies to reduce risk, promote resilience, and ultimately prevent depression in adolescents. Learn about the importance of early identification and about CDRC research and outreach programs that are working to improve our understanding of youth mental health. Anne Fuller, PhD joins us from Xavier University in Cincinnati, Ohio, where she is Assistant Professor in the School of Psychology. She received her Master's and PhD in Clinical Psychology with a child family subspecialty from Loyola University, Chicago, and completed her postdoctoral research with us at the CDRC. Follow us on podbean: utswcdrc.podbean.com Contact us at DecodingDepressionPodcast@UTSouthwestern.edu Learn more about the CDRC: www.utsouthwestern.edu/labs/trivedi www.utsouthwestern.edu/cdrc

Kathryn Forbes interviews Dr. Madhukar Trivedi and three special guests—a clinical psychologist, a pediatrician, and a minister—about adolescent risk and the protective factors that can prevent mood disorders and promote mental health and well-being in adolescents. Matthew Housson PhD, Early Denison MD, and Andy Stoker PhD are all fathers who, together, have nearly 60 years of experience cultivating the minds, bodies, and spirits of children, parents, and families. To learn more, visit their website www.parentingforthepresent.com and listen to the Parenting for the Present podcast where they share best-practices and up-to-date research for practical, proactive parenting. Follow us on podbean: utswcdrc.podbean.com Contact us at DecodingDepressionPodcast@UTSouthwestern.edu Learn more about the CDRC: www.utsouthwestern.edu/labs/trivedi www.utsouthwestern.edu/cdrc

Catherine Huff interviews Dr. Manish Jha and Dr. Madhukar Trivedi. There has been a renewed interest in researching psychedelic-assisted psychotherapy for the treatment of depression, anxiety, and other mental health disorders. But there is still much work to be done to understand this as a potential treatment. What is the mechanism by which psychedelics may work for depression? What are the risks associated with this kind of treatment? What has the research shown? What work needs to be done to have clear evidence of benefit and safety profiles? Dr. Jha has substantial expertise in the conduct of clinical trials and extensive clinical experience in providing care to patients with treatment-refractory psychiatric illnesses. His research uses functional neuroimaging and affective neuroscience experiments to elucidate the neurocircuit mechanisms in order to develop the next generation of circuit-specific treatments for psychiatric disorders. Dr. Jha was involved with studies investigating ketamine for people with major depressive disorder. Follow us on podbean: utswcdrc.podbean.com Contact us at DecodingDepressionPodcast@UTSouthwestern.edu Learn more about the CDRC: www.utsouthwestern.edu/labs/trivedi www.utsouthwestern.edu/cdrc

Catherine Huff interviews Lisa Rigby, Executive Director of Woven Health Clinic, and our own Dr. Madhukar Trivedi, in this episode all about “Integrated Health Care.” How can we work together to better support comprehensive, integrated patient care and bring quality, affordable mental health care to communities around the country? Woven Health is a valued partner of the CDRC’s Mood Disorders Network, having implemented the VitalSign6 program with significant success in clinics across the DFW area. Learn more about Woven Health Clinic at www.wovenhealth.org Follow us on podbean: utswcdrc.podbean.com Contact us at DecodingDepressionPodcast@UTSouthwestern.edu Learn more about the CDRC: www.utsouthwestern.edu/labs/trivedi www.utsouthwestern.edu/cdrc

Catherine Huff interviews Dr. Russell Toll, Dr. Andy Czysz, and Dr. Madhukar Trivedi in this episode "All About TMS." TMS is the acronym for transcranial magnetic stimulation. But what does that mean? How is it used as treatment for depression, and why does it work? Listen as the experts discuss. Andrew Czysz, MD, PhD, is Assistant Professor of Psychiatry at the CDRC and UTSW’s outpatient psychiatry clinic. His research focuses on biomarker discovery for depression, as well as understanding and developing new treatments for mood and substance use disorders. In his clinical practice, Dr. Czysz evaluates and treats patients with treatment-resistant depression using innovative approaches including transcranial magnetic stimulation. Russell Toll, PhD, is Assistant Professor of Psychiatry at the CDRC who serves as the research lead for the CDRC’s Electroencephalography (EEG) and Transcranial Magnetic Stimulation (TMS-EEG) programs. As a US Army combat veteran of the Iraq War, Dr. Toll works on solutions to depression and PTSD through his research on connectivity topographies of mood disorders. Follow us on podbean: utswcdrc.podbean.com Contact us at DecodingDepressionPodcast@UTSouthwestern.edu Learn more about the CDRC: www.utsouthwestern.edu/labs/trivedi www.utsouthwestern.edu/cdrc

Kathryn Forbes interviews Sara Levinson, MPH, MSLOC and Dr. Madhukar Trivedi about the importance of self-monitoring and the work to reduce the burdens associated with mental health screening by putting the power in the hands of individuals. Active self-monitoring helps you quickly notice changes in your mental health, so that you can quickly take action. CDRC researchers designed the Evexia self-monitoring website to empower individuals to screen themselves regularly and track changes in their mental wellness over time. As Senior Project Manager and Head of the CDRC’s Mood Disorders Network (MDN), Sara Levinson works to implement the findings from CDRC research into real world settings. The MDN’s newest project, Evexia, is a tool developed by mental health professionals that empowers youth and adults alike to manage and monitor their mental health from anywhere, at anytime. Ready to get started? You can sign up today for this free and confidential service at www.centerfordepression.org Follow us on podbean: utswcdrc.podbean.com Contact us at DecodingDepressionPodcast@UTSouthwestern.edu Learn more about the CDRC: www.utsouthwestern.edu/labs/trivedi www.utsouthwestern.edu/cdrc

Catherine Huff interviews Dr. Madhukar Trivedi, Founding Director of the CDRC, about the search to identify biosignatures for depression. What were the first biomarker research studies? What are the most promising biomarkers? What is the CDRC studying now? And how will this impact the future of depression treatment? Depression isn’t “one size fits all”, and treatment shouldn’t be, either. Listen to learn about all things biomarkers, and why it is so important to apply precision medicine to depression. Follow us on podbean: utswcdrc.podbean.com Contact us at DecodingDepressionPodcast@UTSouthwestern.edu Learn more about the CDRC: www.utsouthwestern.edu/labs/trivedi www.utsouthwestern.edu/cdrc

This episode discusses youth suicide prevention and school-based programs. Our debut episode discussed youth depression, and now we dig in deeper with a focus on what can be done to support healthier, more resilient youth and young adults. Kathryn Forbes interviews Dr. Madhukar Trivedi, Founding Director of the CDRC, and Dr. Jennifer Hughes, Associate Professor, Licensed Psychologist, and head of the CDRC’s Risk and Resilience Network. To learn more about the Youth Aware of Mental Health program, visit y-a-m.org Follow us on podbean: utswcdrc.podbean.com Contact us at DecodingDepressionPodcast@UTSouthwestern.edu Learn more about the CDRC: www.utsouthwestern.edu/labs/trivedi www.utsouthwestern.edu/cdrc

Kathryn Forbes interviews Dr. Madhukar Trivedi and Dr. Jennifer Hughes about the Texas Youth Depression and Suicide Research Network (TX-YDSRN). Funded by the state as part of the Texas Child Mental Health Care Consortium, TX-YDSRN supports important research into identifying, intervening with, and supporting suicidal adolescents and young adults as well as sharing those findings with health care systems across the state to improve care for all Texans. To learn more about the TX-YDSRN, visit tx-ydsrn.swmed.org Follow us on podbean: utswcdrc.podbean.com Contact us at DecodingDepressionPodcast@UTSouthwestern.edu Learn more about the CDRC: www.utsouthwestern.edu/labs/trivedi www.utsouthwestern.edu/cdrc

Dr. Madhukar Trivedi talks with Catherine Huff about the CDRC's research into biosignatures for depression and how this work will lead to more accurate diagnosis and more personalized and precise treatment options for people living with depression.