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Last week, the FDA and CDC signed off on updated Covid-19 vaccines that target currently circulating variants. It comes amid a recent uptick in hospitalizations and deaths in the United States ahead of winter that could see threats from three respiratory viruses – coronavirus, flu and respiratory syncytial virus. In today’s episode, we answer some frequently asked questions about the updated Covid-19 vaccines and look at how we should approach the virus nearly more than three years after its emergence. Guest: Dr. Sanjay Gupta, CNN Chief Medical Correspondent Listen to Chasing Life here. To learn more about how CNN protects listener privacy, visit cnn.com/privacy

After a series of incidents in San Francisco, California authorities have asked General Motors to take some of its Cruise robotaxis off the road. It comes not long after California regulators gave the greenlight for Cruise and its competitor Waymo to charge for robotaxi rides in the city at any time of day. So what does that mean for the future of driverless cars? In today’s episode, we examine what it’s like to ride in one and why the technology has become a flashpoint in multiple cities. Guest: Veronica Miracle, CNN Correspondent To learn more about how CNN protects listener privacy, visit cnn.com/privacy

As a new NFL season kicks off this week, old questions about the game’s safety are being asked following Damar Hamlin’s on-field cardiac arrest and Tua Tagovailoa’s multiple concussions last year. And it’s not just the pros: youth leagues around the countries have adjusted practice routines and safety protocols to guard against injuries that can carry long-term impacts. In today’s episode, we examine football’s deadly history and how it’s informing today’s game. Plus, CNN gets a look at new technology that could one day predict injuries before they happen. Guest: Coy Wire, CNN Sports Anchor & Correspondent To learn more about how CNN protects listener privacy, visit cnn.com/privacy

Eight Republican presidential candidates took the stage in Milwaukee last week for the first primary debate of the 2024 campaign. Notably missing, however, was frontrunner Donald Trump, who surrendered to Fulton County authorities a day later in the Georgia 2020 election subversion case. In today’s episode, we head to Milwaukee to recap the moments that mattered and to get a sense of how the debate could shape the race going forward. Guests: Dana Bash, CNN Anchor & Chief Political Correspondent Jeff Zeleny, CNN Chief National Affairs Correspondent Kit Maher, CNN Campaign Embed To learn more about how CNN protects listener privacy, visit cnn.com/privacy

It’s been over a week since blazing wildfires ripped through the island of Maui, killing over 100 people and causing billions of dollars of damage. While the outpouring of support has been significant, some locals have voiced anger over the official response, lingering tourist presence, and real estate speculators trying to buy up land. In today’s episode, we hear stories of survival and look at how disasters like this one are forcing communities to ask tough questions about how prepared they are for stronger and faster wildfires. Guest: Bill Weir, CNN Chief Climate Correspondent For more on how you can help the Hawaii wildfire victims, go here. To learn more about how CNN protects listener privacy, visit cnn.com/privacy

Thousands of Hollywood actors and writers have been on strike for weeks demanding raises, regulation of artificial intelligence, and residuals from content created for streaming services. Meanwhile, thousands of hotel workers and public sector employees in Los Angeles have also staged work stoppages as they push for better wages. However, this uptick in labor unrest goes well beyond California. In today’s episode, we look at what’s driving a surge in union membership across the country and look at how presidential politics could play a role in a potential autoworkers strike. Guest: Vanessa Yurkevich, CNN Business and Politics Correspondent To learn more about how CNN protects listener privacy, visit cnn.com/privacy

Donald Trump was indicted Tuesday on criminal charges by a federal grand jury in special counsel Jack Smith’s investigation into efforts to overturn the 2020 election, the latest in a series of unprecedented criminal indictments against the former President. In today’s episode, we examine the historic charges and how it appears prosecutors plan to make their case. Plus, a look at how the Republican frontrunner is expected to navigate a packed courtroom calendar while on the campaign trail. Guest: Elie Honig, CNN Senior Legal Analyst To learn more about how CNN protects listener privacy, visit cnn.com/privacy

A new group of drugs for type 2 diabetes and obesity have shown to be more effective for weight loss than any previous medications. Some medications like Ozempic and Wegovy have surged in popularity thanks in part to celebrity use. But who should be taking them? And are they safe? In today’s episode, we break down the future of the weight loss industry and examine why some of these medications could also help curb addictive behaviors. Guest: Meg Tirrell, CNN Medical Correspondent To learn more about how CNN protects listener privacy, visit cnn.com/privacy

Throughout the month of July, scorching temperatures have broken records on several continents — the latest in a trend caused by the climate crisis. Meanwhile, in the US, extreme rainfall has led to devastating floods and toxic wildfire smoke has drifted down from Canada, prompting unhealthy air alerts in multiple cities. In today’s episode, we break down why this moment is uniquely dangerous and look at how the climate crisis is already forcing people’s hands about where to live. Guest: Bill Weir, CNN Chief Climate Correspondent To learn more about how CNN protects listener privacy, visit cnn.com/privacy

The 2023 Women’s World Cup gets underway this week in Australia and New Zealand, featuring the largest field in tournament history. It comes a year after US Soccer and the United States Women’s National Team struck a deal over equal pay. However, advocates say many disparities remain between the men's and women’s games on the global stage. In today’s episode, we examine what strides towards equality are being made and get a preview of this year’s top teams and players. Guest: Amanda Davies, CNN Sports Anchor To learn more about how CNN protects listener privacy, visit cnn.com/privacy

At least 12 candidates have announced a run for the 2024 Republican presidential nomination, setting up a crowded field ahead of the first primary debate next month. Former President Donald Trump still holds a strong lead in polling despite multiple criminal indictments, so will any candidate be able to unseat him? We look at exactly who is running and examine the different visions of the Republican party they are pitching to voters. Guest: Jake Tapper, CNN Anchor and Chief Washington Correspondent To learn more about how CNN protects listener privacy, visit cnn.com/privacy

More than a week after the aborted Wagner rebellion, it’s unclear what comes next for Russia and President Vladimir Putin. The eventual fate of Wagner boss Yevgeny Prigozhin is also murky after striking a deal with Belarus to end the insurrection. In today’s episode, we head to Moscow to get a view from the ground and examine what the greatest challenge to Putin’s leadership in decades says about his military’s performance in Ukraine. Guest: Matthew Chance, CNN Senior International Correspondent To learn more about how CNN protects listener privacy, visit cnn.com/privacy

A record number of anti-LGBTQ bills have been proposed across the country this year, including a new push to ban access to gender-affirming health care for transgender youth. Beyond the debates and protests, some families are grappling over how to relate to the trans people in their lives. In today’s episode, we hear about a Black minister’s ongoing journey to accept his transgender daughter. Guest: Adrienne Broaddus, CNN Correspondent If you or someone you know is struggling with suicidal thoughts or mental health matters, call or text the Suicide and Crisis Lifeline at 988 in the US. The International Association for Suicide Prevention and Befrienders Worldwide have contact information for crisis centers around the world. To learn more about how CNN protects listener privacy, visit cnn.com/privacy

Last month, some of the top voices in artificial intelligence put out a warning about the technology, saying “mitigating the risk of extinction from AI should be a global priority.” How seriously should we take a warning like that? In today’s episode, we examine what’s behind calls for stricter regulation and explore some of the ways AI is already being used in politics and health care. Guest: Donie O’Sullivan, CNN Correspondent To learn more about how CNN protects listener privacy, visit cnn.com/privacy

Former President Donald Trump has been indicted on 37 counts in the special counsel's classified documents probe, the first time in American history a former president has faced federal charges. It sets up an unprecedented legal clash between President Joe Biden’s Justice Department and his potential 2024 general election opponent. In today’s episode, we break down what we know about the charges against Trump and his aide Walt Nauta. Guest: Paula Reid, CNN Senior Legal Affairs Correspondent To learn more about how CNN protects listener privacy, visit cnn.com/privacy

After weeks of intense negotiations, the Senate passed a bill late Thursday evening that will avert a first-ever US default just days ahead of the deadline. In today’s episode, we examine why neither party is particularly thrilled about the deal and why a similar standoff in 2011 could foreshadow struggles for Republicans as they try to implement spending cuts. Guest: Tami Luhby, CNN Senior Writer To learn more about how CNN protects listener privacy, visit cnn.com/privacy

In 2021, a blog post forced the US Coast Guard to confront a problem that had gone unchecked for years. A 19-year-old woman said she was raped while training to work on commercial ships. Then more sexual assault survivors in the industry came forward. In today’s episode, we hear why these women went public and what’s being done about it. Read more here. Guest: Blake Ellis & Melanie Hicken, CNN Investigates Senior Writers To learn more about how CNN protects listener privacy, visit cnn.com/privacy

This week marks one year since 19 students and two teachers were killed in a shooting at Robb Elementary School in Uvalde, Texas. In that time, victims’ families say they have not received sufficient answers from authorities as to why they waited 77 minutes before breaching the classroom. In today’s episode, we hear why CNN agreed to show some parents unreleased body camera footage and examine how surviving students are coping. Guest: Shimon Prokupecz, CNN Senior Crime & Justice Correspondent To learn more about how CNN protects listener privacy, visit cnn.com/privacy

Many Western cities are grappling with large encampments on the streets as homeless populations grow. In Phoenix, a judge recently ordered one such encampment to be cleared after local residents sued the city for violating public nuisance laws. In today’s episode, we hear from people living in that camp about what comes next and why advocates fear similar legal strategies could soon be used in other cities. Guest: Gabe Cohen, CNN Correspondent To learn more about how CNN protects listener privacy, visit cnn.com/privacy

The Biden administration is preparing for an influx of migrants at the US-Mexico border when the Covid-era border restriction known as Title 42 expires later this week. Officials in El Paso, Texas say they are already running out of space to house asylum seekers. In today’s episode, we hear from migrants on both sides of the border and look at how the policy shift could be felt in other cities across the country. Guest: Rosa Flores, CNN Correspondent To learn more about how CNN protects listener privacy, visit cnn.com/privacy