The Empowering Neurologist Podcast

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 Without question, a pivotal player in our health is the adequate and balanced functioning of the immune system. No matter what disease state you can consider, the immune system is playing an important role. We now recognize that our metabolic health is hugely influential in determining the functionality of our immune system. As such, we know that our lifestyles influence metabolic health and therefore, with this understanding, we can influence immune function by paying attention to these decisions we make each day that are so influential as it relates to human metabolism. On today's program, we are going to explore the concept of immune modulation and the relationship between immunity and metabolic health. We are also going to take a deep dive into new some very exciting discoveries as it relates to ancient foods that powerfully influence immune function including Himalayan tartary buckwheat, a modern day superfood that’s getting a lot of attention. There couldn't be anyone better to walk us through this exciting new science than my longtime friend, Dr. Jeffrey Bland. This is a fascinating and thought provoking interview. To further explore this science, visit Big Bold Health: https://bigboldhealth.com/the-science ==== 0:00 Intro 4:25 The Immune System Connects Everything 13:27 Soil Health & Agricultural Toxins 19:01 Looking at the True Quality of Our Food 22:33 Discovering Himalayan Tartary Buckwheat 28:38 Polyphenols & Benefits of HTB 33:38 Longevity & Blue Zones 37:43 Forming a Super Superfood: Sprouting HTB 39:49 The True Interconnected Nature of the Body & Immune System 54:07 The Mystery of Ancient Medicine & Nature’s Intelligence 1:00:01 Taking a Closer Look at Functions 1:02:03 Conclusion ==== Jeff Bland, PhD is the founder of Big Bold Health, a company on a mission to transform the way people think about one of nature’s greatest innovations — the immune system. Through Big Bold Health, Jeff is advocating for the power of Immuno-Rejuvenation to enhance immunity at a global level, often through the rediscovery of ancient food crops and superfoods. To get there, Jeff is building a network of small farms and suppliers throughout the US that take a clear stance on regenerative agriculture, environmental stewardship, and planetary health. Jeff’s career in health spans more than 40 years. A nutritional biochemist by training, he began in academia as a university professor. Jeff then spent three decades in the natural products industry, working alongside other pioneers. A lifelong educator, Jeff has traveled the world many times over in his role as the “father of functional medicine.” In 1991, he and his wife, Susan, founded The Institute for Functional Medicine. In 2012, Jeff founded another educational nonprofit called the Personalized Lifestyle Medicine Institute. Jeff is the author of The Disease Delusion: Conquering the Causes of Chronic Illness for a Healthier, Longer, and Happier Life, as well as countless additional books and research papers. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 As many of you are aware, much of our information that we present deals with problems of the brain and spinal cord. These have been described as being parts of the central nervous system. However, there is another part of the nervous system called the peripheral nervous system that is basically made up of the peripheral nerves. Peripheral neuropathy is a term that describes an abnormality with peripheral nerves. This can cause loss of sensation, pain, or even loss of autonomic function. Here in America some 20 million people suffer from peripheral neuropathy. In fact more than half of the people with diabetes will develop prayerful neuropathy at some point in their lifetimes. We are at increased risk for peripheral neuropathy not only as a consequence of diabetes but also as we age. Pray for neuropathy can be caused by chemotherapy and fully 1/4 of all peripheral neuropathy patients do not have an identifiable cost. There aren't really any FDA approved treatments to actually treat purple neuropathy in terms of the underlying cause of the nerve damage. While we do have drugs that treat, pain for example, again we need to find a way of treating the fire, not just focusing on the smoke. Having said that, there is an exciting new development in this field using drugs that are already available and are called muscarinic antagonists. Basically, they block the transmission of acetylcholine. In today's podcast, we are going to explore deeply, the mechanisms whereby this approach, using these muscarinic antagonists seems to be incredibly effective in growing new nerve fibers as well as increasing metabolism in the nerve itself leading to improvement ultimately in the manifestation of peripheral neuropathy. === 0:00 Intro 5:35 The Scope of the Problem 8:09 Diabetic Neuropathy 11:49 Neuropathy Following Chemotherapy 14:21 Viral Infections: HIV Treatment & Covid 16:56 Why Mitochondria are Essential in This 19:44 Pharmaceutical Study of Neuropathy 24:57 Aldose reductase inhibitor 29:31 Why This Approach is Different 37:44 How Antimuscarinics Work 48:10 Metrics for Getting FDA Approval 58:42 Funding the Research 1:01:53 Conclusion ==== Nigel A. Calcutt, Ph.D. ook both his B.Sc. in Zoology and Ph.D. Physiology and Pharmacology at Nottingham University, England. Dr. Calcutt first began studying nerve damage caused by diabetes as an undergraduate, with a largely unsuccessful but nevertheless entertaining and informative attempt to generate diabetic chickens in the laboratory of the esteemed ornithologist Professor David Tomlinson. Undeterred by the pitiful paucity of pre-diabetic poultry, he has continued to investigate mechanisms of diabetic neuropathy and neuropathic pain throughout his academic career, with a particular interest in translational studies. Dr. Calcutt is also a co-founder of the biotechnology company WinSanTor Inc. and the non-profit organization Diabetes Research Connection. Paul Fernyhough PhD received his PhD in biochemistry from the department of Biochemistry at University of Sheffield. He then carried out postdoctoral research at Colorado State University, Kings College London and as a Wellcome Trust Postdoctoral Fellow at St Bartholomew’s Medical College. Dr. Fernyhough’s research interest is in the cell biology underlying neurodegenerative disorders of the peripheral nervous system with a focus on the impact of diabetes. A biotech start-up, WinSanTor Inc, has been established and is directing phase 2 clinical trials in diabetic neuropathy and chemotherapy-induced peripheral neuropathy. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 In a groundbreaking development, an international team of researchers has unveiled a remarkable advancement in the fight against progressive multiple sclerosis (MS). Their study, led by scientists from the University of Cambridge, the University of Milan Bicocca, and Hospital Casa Sollievo della Sofferenza in Italy, demonstrates the safety, tolerance, and long-lasting effectiveness of injecting a specific type of stem cell directly into the brains of patients living with progressive MS. This breakthrough paves the way for the development of advanced cell therapy treatments for this debilitating disease that affects over 2 million people worldwide. Multiple sclerosis is a complex autoimmune disease that targets the central nervous system, leading to severe disruption in the transmission of nerve signals. While there are treatments available to alleviate some of the symptoms and reduce the frequency of relapses, many patients still progress into a secondary phase of the disease, which steadily worsens over time, causing severe disability. This secondary progressive phase has long been a significant challenge in the treatment of MS. In progressive forms of MS, a type of immune cell known as macrophages, specifically microglial cells, plays a crucial role in attacking and damaging the central nervous system. This relentless assault leads to chronic inflammation and extensive nerve cell damage. Recent advances in stem cell therapies have raised hope that they could help mitigate this damage by replacing damaged cells with healthy ones. Before the current study, the University of Cambridge team had already demonstrated in mouse models that reprogrammed skin cells into brain stem cells, transplanted into the central nervous system, could reduce inflammation and potentially aid in repairing MS-related damage. This groundbreaking study marks a significant step forward in the pursuit of effective treatments for secondary progressive MS. Although the study is relatively small and may have confounding effects from immunosuppressant drugs, its safety and long-lasting effects over the 12-month trial period have paved the way for further clinical trials. The research team's cautious optimism fuels hope for the development of cell therapy as a potential solution for this debilitating condition. This exciting progress holds the promise of a brighter future for the millions of people living with progressive MS, offering renewed hope for a more effective treatment approach. Our interview today is with the lead researcher involved in this study at the University of Cambridge, Stefano Pluchino, MD, PhD. ==== 0:00 Intro 2:46 Why Stem Cell Therapy Works 5:10 Studying Stem Cells on the Brain 9:15 MS Patients Studied in This Trial 13:43 What the Results Mean for the Public 17:40 The Specifics of the Study 26:18 Rigorous Testing that Sets this Trail Apart 28:25 Findings: Feasibility, Safety, and Biomarkers 34:32 Looking at the Results over 12 months 40:11 Correlation of Metabolic Health and MS 44:55 What Exosomes Reveal About Disease 49:01 Senolytic Therapy & Neurodegenerative Diseases 53:36 Conclusion ==== Stefano Pluchino received his MD and PhD degrees at the University of Siena, Italy, and additional training at Cambridge University, UK. He is currently Professor of Regenerative Neuroimmunology (2021) and Honorary Consultant in Neurology, within the Department of Clinical Neurosciences at Cambridge University. Twitter: @Pluchinolab Research: https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(23)00393-4 ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 In this episode of The Empowering Neurologist, we're diving into two topics that are gaining significant attention in the worlds of men's health and weight loss: the importance of testosterone replacement therapy and the emerging role of GLP-1 agonists in weight loss as well as in diabetes treatment. Joining us is an esteemed expert in this field, Dr. Tracy Gapin, a renowned urologist and men's health specialist. Why is this topic so crucial? Testosterone, often hailed as the cornerstone of male vitality, plays a central role in various aspects of men's health. It's not just about physical strength or libido; testosterone impacts mood, energy levels, bone density, muscle mass, cognitive function, and overall well-being. However, as men age, testosterone levels naturally decline, leading to a condition known as hypogonadism or low testosterone. This decline can have profound effects on a man's health and quality of life. Dr. Gapin, with his extensive experience and research in the field, sheds light on how testosterone replacement therapy can be a game-changer for men experiencing the effects of low testosterone. He delves into the nuances of identifying candidates for this therapy, the benefits, and the misconceptions surrounding it. His insights are particularly valuable in a time when discussions about men's hormonal health are often overshadowed or misunderstood. Further, as he explains, age-matched testosterone levels in men have plummeted over the past several decades, and we discuss why. In addition, Dr. Gapin takes us through the exciting world of GLP-1 agonists, a class of drugs initially developed for diabetes management but now having a major impact in the weight loss arena. Obesity is a mounting concern globally, and its impact on men's health is undeniable. With cardiovascular disease, diabetes, and a host of other conditions linked to obesity, finding effective weight management solutions is paramount. Dr. Gapin explains how GLP-1 agonists work, their benefits, their potential risks, and their role in revolutionizing weight loss treatments. This episode is not just for those directly experiencing these issues but also for anyone interested in the broader conversation about men's health. Whether you're a healthcare professional, someone exploring options for personal health improvement, or simply curious about the latest in medical advancements, Dr. Gapin's insights offer valuable knowledge and perspective. ==== 0:00 Intro 3:04 The Issues of Low Testosterone 7:07 Why Testosterone Levels are Falling 10:00 What Indicates Low Testosterone 15:00 The Holistic Approach to This 17:28 Why Testosterone Replacement Therapy May Be Essential 19:53 Addressing Potential Risks 28:20 How TRT Works & What to Expect 35:49 Looking at Estrogen and Progesterone 37:23 LDL Medication and Low Testosterone 39:55 Addressing Thyroid Functionality 40:56 Honest Thoughts on Ozempic 50:28 Conclusion ==== Tracy Gapin, MD, is a board-certified urologist, men’s health and performance expert. and founder of the Gapin Institute, a global leader in high performance medicine. He has over 20 years of experience focused on providing executives, entrepreneurs and athletes a personalized path to optimizing their health so they can have exceptional energy, laser-focused mind and a better body. Text HEALTH to 26786 to receive an electronic copy of the High Performance Health Handbook for Men ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 Hello everyone. I am delighted to let you all know about this episode of The Empowering Neurologist. We discuss fundamentally important new book, The Autoimmune Cure, by one of my dearest friends on the planet, New York Times bestselling author, Dr. Sara Gottfried. In this interview, Dr. Gottfried enlightens us as to what is really underlying the vast array of autoimmune conditions. Yes, we do get into the weeds, but the information she provides is not just fascinating, but fully empowering as well. Prepare to be enlightened as she sheds light on how trauma can intricately rewire our bodies, ultimately becoming the catalyst for autoimmune diseases. With a prevalence that's skyrocketing globally, autoimmune conditions affect millions, yet the root cause often remains elusive. Conventional medicine's approach often falls short in effectively diagnosing and treating autoimmune disorders. Many individuals grapple with baffling symptoms ranging from fatigue to brain fog, from aches and pains to anxiety, unaware that their immune system is the culprit behind their distress. Drawing from her wealth of experience in precision medicine, Dr. Gottfried has uncovered a compelling correlation between autoimmune disease and a history of trauma, a revelation that's shaping the future of autoimmune care. But here's the exciting and empowering part—there's hope. Dr. Gottfried's revolutionary program outlined in he Autoimmune Cure offers a beacon of hope for those navigating the treacherous waters of autoimmune ailments. By addressing the root cause head-on and providing a comprehensive roadmap to reset the immune system, this program empowers individuals to reclaim their health and vitality. So, join us as we embark on a transformative journey towards autoimmune liberation. Whether you're grappling with autoimmune symptoms yourself or seeking to deepen your understanding of immune health, this podcast episode promises to be a beacon of insight and inspiration. ==== 0:00 Intro 2:15 We’re Looking at Autoimmune Wrong 8:04 Using Psychedelics for Healing Trauma 12:58 Long Covid’s Impact on the Body 16:11 Thyroid Disruption 19:03 The Microbiome’s Impact on Immune Function 24:55 Symptoms Checklist & MS 30:26 Why Women have a Higher Risk 37:19 Praise for Dr. Gottfried’s World 44:29 Conclusion ==== Sara Szal Gottfried MD is a physician, researcher, author, and educator. She graduated from Harvard Medical School and MIT, and completed residency at UCSF, but is more likely to prescribe a CGM and personalized nutrition plan than the latest pharmaceutical. Dr. Gottfried is a global keynote speaker and the author of four New York Times bestselling books about hormones, nutrition, and health. Her latest book is called THE AUTOIMMUNE CURE (March 2024). She is Clinical Assistant Professor in Dept. of Integrative Medicine and Nutritional Sciences at Thomas Jefferson University, and Director of Precision Medicine at the Marcus Institute of Integrative Health. She takes care of executives and professional athletes. Her focus is at the interface of mental and physical health, N-of-1 trial design, personalized molecular profiling, use of wearables, and how to leverage these tools to improve health outcomes. Learn more at SaraGottfriedMD.com ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 With so much discussion these days centered on metabolic health and issues like overweight, obesity, diabetes, and the downstream consequences of these health challenges, I think it's important to spend some time looking at what may be one of the pivotal causes of metabolic disturbances, the consumption of fructose sugar. As such, I reached out to Dr. Richard Johnson, a world’s authority on the role of fructose in human metabolism, to share with us his latest thoughts not only related to fructose, but also including the various types of sweeteners that are available and have become very popular. This discussion will take us into the world of GLP-1, a receptor that is stimulated by drugs like Ozempic. And no doubt, that is an area of discussion that is interesting for so many people. We begin our discussion however with Dr. Johnson describing his recent trip to Dubai where he attended the COP 28 climate conference which, interestingly, includes his insights related to the threats posed by climate change on human metabolism. Let me tell you a little bit more about Dr. Richard Johnson.He was formerly the chief of the Renal Division and Hypertension at the University of Colorado for nine years. He’s a physician, trained in internal medicine, infectious disease, and nephrology. Dr. Johnson is a widely cited NIH-funded scientist who has lectured in over 40 countries and has authored three books, The Sugar Fix, The Fat Switch, and the new Nature Wants Us to Be Fat. Rick has a special interest in the role of sugar and especially fructose and its byproduct uric acid in driving metabolic and kidney disorders. And most recently he has been exploring the biological properties of a unique sugar, allulose, a topic we discuss in great depth. ==== 0:00 Intro 1:56 Climate Change and Rising Health Concerns 12:53 Correlation of Uric Acid and Impulsivity 20:50 The Mechanics of Obesity as a Low Energy State 26:12 How Our Biology Supports Weight Gain 28:38 Impact of Sugar and Carbs on the Body 31:50 Should you avoid fruit? 33:09 What We should Be Doing 35:03 The World of Low Calorie Sugars 37:55 Disadvantages of Artificial Sweeteners 41:32 Allulose: The Next Best Thing? 54:19 How CGMs Will Change Your Perspective 55:10 The Role of Quercetin on Mitophagy 58:20 Conclusion ==== Dr. Johnson has performed medical research since the early 1980s and has been funded by the NIH since 1987. Most of his research has focused on the pathogenesis of kidney diseases, but during the last 12 years his studies have also included studies of the pathogenesis of primary hypertension, insulin resistance and diabetes, diabetic nephropathy, and obesity. Much of his work has involved a combination of cell culture and animal models with a strong translational component, but he has also been involved in a number of clinical trials and epidemiology-based studies. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

Interested in an Apollo device? Click the following link and use code PERLMUTTER for a 15% OFF discount. https://apolloneuroscience.pxf.io/c/4460811/1861953/12331 🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 Clearly, we've communicated a lot of information indicating that it's really fundamentally important for our health and ability to resist disease that we gain control over things like anxiety, lack of restorative sleep, lack of exercise, and certainly make other good choices like eating appropriately as well. These are powerful modulators of our metabolic health I have wide ranging implication not just as it relates to the brain, but our entire physiology. How exciting is that we live in the day and age of wearable devices. And, importantly, we now see the development of a wearable device that specifically allows us in a non pharmaceutical way to deal with anxiety, help us through the days it relates to our decision making ability, and even help us in the night as a relates to sleep, and it’s called Apollo. I thought it would be a great idea to interview the creator of this device, Dr. David Ravin. Dr. David Rabin, MD, PhD, a board-certified psychiatrist and neuroscientist, is the co-founder & chief medical officer at Apollo Neuroscience, the first scientifically-validated wearable system to improve heart rate variability, focus, relaxation, and access to meditative states by delivering gentle layered vibrations to the skin. In addition to his clinical psychiatry practice, Dr. Rabin is also the co-founder & executive director of The Board of Medicine, and a psychedelic clinical researcher currently evaluating the mechanism of psychedelic-assisted psychotherapy in treatment-resistant mental illnesses. This is a very interesting podcast about a very interesting and clearly beneficial wearable device. I have found that using this device my heart rate variability has gone up dramatically, which is a good thing, and something I have been trying to accomplish for quite some time. This has huge implications for health. I hope you enjoy this information. ==== 0:00 Intro 3:09 Where It All Began - Searching for Stress Solutions 7:18 MDMA Therapy for PTSD 9:52 Why the Pushback on Psychedelic Therapy? 12:20 New Wearable Tech that Simulates MDMA Benefits 19:56 Creating the Apollo 24:53 Key Metric: Heart Rate Variability 29:10 Dr. Perlmutter’s Success Story with the Apollo 34:32 Perceived vs Real Threat in Anxiety 36:53 Other Success Stories with Apollo 42:51 Solving the Problems of Sleep 50:04 Conclusion ==== Dr. David Rabin, MD, PhD, a board-certified psychiatrist and neuroscientist, is the co-founder & chief medical officer at Apollo Neuroscience, the first scientifically-validated wearable system to improve heart rate variability, focus, relaxation, and access to meditative states by delivering gentle layered vibrations to the skin. In addition to his clinical psychiatry practice, Dr. Rabin is also the co-founder & executive director of The Board of Medicine, and a psychedelic clinical researcher currently evaluating the mechanism of psychedelic-assisted psychotherapy in treatment-resistant mental illnesses. Socials: Drdave.io Apolloneuro.com Boardofmedicine.org Twitter: @daverabin Instagram: @drdavidrabin ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

To save 15% off an Apollo device, click THIS LINK and use code PERLMUTTER at checkout. 🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 One area that we spend a lot of time exploring focuses on the role of lifestyle choices as they relate to brain, health, functionality, and resistance to disease. I have to admit, over the years I have perhaps somewhat neglected a very important tool that offers up incredible utility as a relates to doing good things for the brain, and that is art. With that in mind, I felt it would be a great idea to interview the authors of an exciting new book that explores this very topic entitled, Your Brain on Art by Susan Magsamen and Ivy Ross. Your Brain on Art explores the vital role of arts in our lives, beyond mere entertainment. The book reveals a cultural evolution where arts emerge as powerful, accessible solutions for overall well-being. The authors present robust research highlighting the health benefits of art engagement. They illustrate how just 45 minutes of an art activity can significantly reduce stress hormones regardless of skill level, and regular artistic engagement could potentially extend life expectancy by a decade. The book delves into how music fosters cognitive abilities, the therapeutic effects of sound vibrations, the innovative use of virtual reality in therapy, and how interactive art experiences enhance memory and sensory engagement. It also discusses how art is being integrated into medical prescriptions for various health issues like loneliness and dementia. Your Brain on Art serves as a gateway to understanding the intersection of arts, aesthetics, and wellness. It includes discussions with renowned figures like David Byrne, Renée Fleming, and E. O. Wilson, offering a comprehensive view of neuroaesthetics. This guide combines cutting-edge research, multidisciplinary expert insights, and inspirational stories, showcasing how arts significantly improve life quality. ==== 0:00 Intro 3:07 How Susan & Ivy Began Studying Art 9:20 Why Art is Necessary for Humanity 14:22 Your Brain on Art 18:50 How Observing Art Helps Us 20:34 Reducing Amygdala Actions 22:16 The Healing Power of Sound and Vibration 25:18 The Role of Aesthetics & Awe of Nature 32:06 Poetry: the Oldest Art Form 34:48 Treating Mental Illness with Art 40:06 Why Talent Doesn’t Matter 44:14 Creative Flow & Mindfulness 45:34 Theatre & Connecting to Our Emotions 51:04 Psychedelics for Healing 57:30 The Art of Food 1:00:51 Conclusion ==== Susan Magsamen is the founder and executive director of the International Arts + Mind Lab (IAM Lab), Center for Applied Neuroaesthetics, a pioneering neuroaesthetics initiative from the Pedersen Brain Science Institute at Johns Hopkins University School of Medicine. Susan’s work focuses on how the arts and aesthetic experiences measurably change the brain, body and behavior and how this knowledge can be translated to inform health, wellbeing and learning programs in medicine, public health and education. Magsamen is also the co-author of the New York Times Bestseller, Your Brain on Art: How the Arts Transform Us written for the general public. === Ivy Ross is the Vice President of Design for the Hardware organization at Google. Over the past six years, she and her team have launched 50+ products winning over 240 global design awards. This collection of hardware established a new Google design aesthetic that is tactile, colorful, and bold. Most recently, Ivy co-authored with SusanMagsamen Your Brain on Art: How the ArtsTransform Us. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

Get up to 53% off the P600 cookware and a FREE set of silicone utensils: https://chefsfoundry.com/DrPerlmutter 🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 Loneliness is pervasive in our modern world. The sense of isolation and lack of connection, clearly made worse by the COVID pandemic, is associated with a wide scope of health issues and even mortality. So what do we do? Some important steps are presented in our podcast, an interview with the author of Project Unlonely - Healing Our Crisis of Disconnection, Dr. Jeremy Nobel. Jeremy Nobel, M.D., MPH, is a primary-care physician, public health practitioner, and award-winning poet with faculty appointments at the Harvard T.H. Chan School of Public Health and the Harvard Medical School. He is the founder and president of the Foundation for Art & Healing (www.ArtandHealing.org), whose signature initiative, Project UnLonely, addressing the personal and public health challenges of loneliness and social isolation, has gained national visibility. This is an important topic, not just for the elderly, living alone, but for all of us. For it is clear that any of us can feel lonely and disconnected, even in the midst of our busy lives. ==== TIMESTAMPS: 0:00 Intro 2:10 Our Epidemic of Loneliness 6:11 Leveraging the Creative Arts for Healing 12:21 Evaluating Loneliness in Studies 16:31 How Loneliness Equates to Heightened Disease Risk 19:43 The Loneliness Spiral 21:56 Inflammation 24:38 How World Events Impact Well-Being 26:45 What You Can Do: Art as a Medium for Healing 31:05 How Psychedelics Overlap with Creativity 35:44 Cultural Norms Impact Loneliness 38:31 The Biggest Challenge for Moving Forward 40:57 The Potential of Awe and Nature-Connection 44:24 Correlation Between Loneliness and FMRI Imaging 50:00 Conclusion ==== JEREMY NOBEL, M.D., MPH, is a primary-care physician, public health practitioner, and award-winning poet with faculty appointments at the Harvard T.H. Chan School of Public Health and the Harvard Medical School. He is the founder and president of the Foundation for Art & Healing (www.ArtandHealing.org), whose signature initiative, Project UnLonely, addressing the personal and public health challenges of loneliness and social isolation, has gained national visibility. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1 See omnystudio.com/listener for privacy information.

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 Who knew? The same mechanisms that are involved in brain degeneration, cardiovascular disease, and virtually any other chronic degenerative decline that we experience in our bodies is also at play on our bodies, meaning affecting our skin. Yes, free radical mediated stress and inflammation are the pillars of what causes good skin to go bad. So, with that in mind I felt it would be terrific to interview a leader in holistic approaches to skin care and plastic surgery, Dr. Anthony Youn. Let me tell you more about him. Known as America's Holistic Plastic Surgeon®, Anthony Youn, M.D. F.A.C.S is a nationally-recognized, board-certified plastic surgeon. Recognized as a leader in his field, he is the author of the best-selling books “The Age Fix," "In Stitches," and “Playing God.” His public television special, The Age Fix with Dr. Anthony Youn, has been viewed by millions. Dr. Youn also hosts the popular podcast The Holistic Plastic Surgery Show. He is the most followed plastic surgeon on social media, with over 4.5 million subscribers on his YouTube Channel and 8 million followers on TikTok. His new book, “Younger for Life” is a complete holistic guide to turning back the clock using the process of Autojuvenation®. I learned an awful lot today on this podcast and hope you do too. ==== TIMESTAMPS: 0:00 Intro 3:00 Dr. Youn’s Wake-up Call From Plastic Surgery 7:05 5 Accelerates for Skin Aging 10:44 What Causes Loss of Collagen 14:59 Healing the Skin Microbiome 17:38 Challenging the Dogma of Plant-Based Collagen 20:24 How to Supplement Collagen 21:29 Skin Cancer, Sun Exposure & Healthy Sunscreens 30:18 How Our Food Choices Cause Skin Inflammation 34:39 Autophagy: Small Steps that Lead to Big Changes 41:03 Botox & Fillers: What You Should Know 43:46 Conclusion ==== Known as America's Holistic Plastic Surgeon®, Anthony Youn, M.D. F.A.C.S is a nationally-recognized, board-certified plastic surgeon. Recognized as a leader in his field, he is the author of the best-selling books “The Age Fix," "In Stitches," and “Playing God.” His public television special, The Age Fix with Dr. Anthony Youn, has been viewed by millions. Dr. Youn also hosts the popular podcast The Holistic Plastic Surgery Show. He is the most followed plastic surgeon on social media, with over 4.5 million subscribers on his YouTube Channel and 8 million followers on TikTok. His new book, “Younger for Life” is a complete holistic guide to turning back the clock using the process of Autojuvenation®. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1 See omnystudio.com/listener for privacy information.

🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 Get a special sneak peek of Calm Your Mind with Food here if you join Dr. Uma’s weekly email list: https://umanaidoomd.com/pages/calmyourmindwithfoodsneakpeek Want even more? Get a special introduction to Nutritional Psychiatry for reducing anxiety and depression symptoms in a special 6-lesson mini-course from Dr. Uma, bundled with a copy of her book: https://umanaidoomd.com/products/calm-your-mind-with-food-anti-anxiety-course-book-bundle ==== Anxiety issues are certainly pervasive, and becoming much more common in our very stressful world. Generally, to go to therapy for dealing with anxiety seems to be pharmacotherapy, in other words, drugs. And while drugs may take the edge off and prove to be effective, it's good to know there are other ideas that are being considered. One important inroad into treating anxiety focuses on dietary change. We know that the consumption of the typical standard American diet is fraught with issues including posing a threat to metabolism by virtue of our consumption of large amount of ultra process foods which actually make up between 52 to 54% of of the calories consumed every day in American adults. This is a diet that has been associated with a dramatic increase risk for metabolic issues, cardiovascular disease, and even threatens the brain. As we will learn today, our consumption of these highly refined foods plays a role in creating anxiety as well. Our guest today is Dr. Uma Naidoo, and we will be discussing her new book, Calm Your Mind with Food - A Revolutionary Guide to Controlling Your Anxiety. Please enjoy the podcast. ==== 0:00 Intro 3:42 The Rising Problem of Anxiety 6:37 Nutritional Psychiatry: Eating for Mental Health 9:51 Foods that Cause Anxiety 13:20 The Process of Healing Through Food 16:50 How We Can Gauge Progress 19:40 Helpful Lab Studies & Food Allergies 23:22 The Benefits of Supplements & Which to Take 28:04 Metabolic Issues & Anxiety 30:23 Bringing Medical Specialities Together 34:16 Starting Small and Regaining Control 37:35 Commonly Used Drugs that Impact Mood Disorders 39:33 Leptin Levels and Anxiety 42:13 The Future of Nutritional Psychiatry 45:20 Conclusion ==== Michelin-starred chef David Bouley described Dr. Uma Naidoo as the world’s first “triple threat” in the food and medicine space: a Harvard-trained psychiatrist, professional chef graduating with her culinary schools’ most coveted award, and a trained Nutrition Specialist. Her nexus of interests have found their niche in Nutritional Psychiatry. Dr. Naidoo founded and directs the first hospital-based Nutritional Psychiatry Service in the United States. She is the Director of Nutritional and Lifestyle Psychiatry at Massachusetts General Hospital (MGH) & Director of Nutritional Psychiatry at MGH Academy while serving on the faculty at Harvard Medical School. She is considered Harvard’s Mood Food Expert and has been featured in the Wall Street Journal, Goop, Live with Kelly & Ryan, and more. Dr. Naidoo is also the national bestselling author of This Is Your Brain on Food: https://umanaidoomd.com/collections/this-is-your-brain-on-food, and the upcoming title that we will discuss today, Calm Your Mind With Food https://umanaidoomd.com/collections/calm-your-mind-with-food ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1 See omnystudio.com/listener for privacy information.

Get up to 53% off the P600 cookware and a FREE set of silicone utensils: https://chefsfoundry.com/DrPerlmutter 🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: https://www.drperlmutter.com/ ✉️🌱 Allulose as a sugar is getting a lot of well deserved attention. We are seeing some pretty remarkable science with respect to allulose as it relates to metabolic health and specifically, weight loss. I felt, as such, that it would be a good idea to interview Dr. Benjamin Bikman on the Empowering Neurologist program today. Let me tell you more about Dr. Bikman. Benjamin Bikman earned his Ph.D. in Bioenergetics and was a postdoctoral fellow with the Duke-National University of Singapore in metabolic disorders. Currently, his professional focus as a scientist and professor (Brigham Young University) is to better understand the role of elevated insulin and nutrient metabolism in regulating obesity, diabetes, and dementia. In our time together, we discuss the important science of allulose as it relates to fat distribution in the body, insulin resistance, heart disease, fatty liver disease, cognitive decline, and even how allulose is able to lower uric acid, an area that I'm certainly interested in. I hope you enjoy this fascinating interview with Dr. Benjamin Bikman. ==== TIMESTAMPS: 0:00 Intro 2:08 The Study of Metabolism 4:53 Dr. Bikman's Insulin Research 7:08 Why People's Bodys Aren’t Able to Use Insulin Correctly 10:12 What Causes Spikes in Insulin Levels 14:59 Problem with Annual Fasting Blood Sugar Test 17:24 Merits of a Continuous Glucose Monitor 19:53 New Sugar Replacement: Allulose 30:43 Bringing Down Uric Acid with Allulose 33:17 Allulose & Insulin Resistance 35:52 Reducing Fatty-Liver Disease Risk 38:48 Protecting Mitochondria Against Cardiovascular Disease 42:00 Cognitive Decline & Allulose 44:42 Preventing Alzheimers 51:28 Conclusion ==== Benjamin Bikman earned his Ph.D. in Bioenergetics and was a postdoctoral fellow with the Duke-National University of Singapore in metabolic disorders. Currently, his professional focus as a scientist and professor (Brigham Young University) is to better understand the role of elevated insulin and nutrient metabolism in regulating obesity, diabetes, and dementia. Dr. Bikman is the author of the book: Why We Get Sick Dr. Bikman’s education platform: https://www.insuliniq.com/ ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1 See omnystudio.com/listener for privacy information.

Visit puritycoffee.com/empoweringneurologist for more information on Balance and use code PERLMUTTER for 30% off a one-time purchase of Balance. Applies to both 12oz bags and 5lb bags. 🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱 Without question, melatonin may well be the most popular nutritional supplement that people are talking about these days, and with good reason. There is an extensive body of science that looks at the use of melatonin in humans and the results of the research are certainly intriguing. Dr. Deanna Minich has been at the forefront of melatonin research for the past several years. She brings to our attention some interesting new insights as a relates to using melatonin, including ways to optimize and personalize its use. Today on this podcast, we will discuss how melatonin interacts with our light exposure and how we can adjust our blue light exposure, especially at night, to maximize the effectiveness of melatonin. We will learn how to enhance melatonin functionality by making sure our vitamin D levels are where they need to be. We will explore melatonin in the wider context of our overall antioxidant status and our discussion will reveal differences in melatonin availability between men and women. When should we take melatonin, what's your dosage be, and how do we adjust our dosage based upon the cycles of the moon? These are interesting questions, for sure. Dr. Minich does exemplary job in explaining these and other questions, and offers up some intriguing information as a relates to possible interactions between melatonin habits like caffeine consumption. I hope you enjoy the program today. I know I found it very informative. ==== TIMESTAMPS: 0:00 Intro 2:20 The Origin on Melatonin Supplements 9:24 Understanding Receptors: Time of Day & Dosages 13:07 Purity Coffee: Better For You Energy 14:15 How Light & Darkness Affects Melatonin 21:13 Setting a Caffeine Curfew 25:38 Antioxidants & Melatonin 28:58 Gender Specificities for Melatonin 31:28 Impact on the Gut Microbiome 33:19 How to Get Started on Supplements 36:10 Why Plants Make Melatonin 37:25 How the Moon Cycle Affects Melatonin 39:25 Melatonin: A Molecule of Consciousness 45:14 How Stress Impacts Melatonin 47:40 Wearable Technology 49:01 Rebound: Waking Up in the Middle of the Night 57:33 Conclusion ==== Deanna Minich, MS, PhD, CNS, Certified Functional Medicine Practitioner (IFMCP), is a nutrition scientist, international lecturer, teacher, and author, with over twenty years of experience in academia and in the food and dietary supplement industries. Throughout the years, she has been active as a functional medicine clinician in clinical trials and in her own practice (Food & Spirit™), which has now become oriented towards groups, workshops, and retreats. She is the author of six consumer books on wellness topics, four book chapters, and fifty scientific publications. Her academic background is in nutrition science, including a Master of Science (M.S.) degree in Human Nutrition and Dietetics from the University of Illinois at Chicago (1995) and a Doctorate (Ph.D.) in Medical Sciences (nutrition focus) from the University of Groningen in the Netherlands (1999). Review article on melatonin authored by Dr. Minich: https://www.mdpi.com/2072-6643/14/19/3934/htm Published article comparing plant melatonin to synthetic melatonin: https://www.mdpi.com/1420-3049/26/19/6087 Research website on melatonin: https://www.phytomelatonin.com/ ==== Visit puritycoffee.com/empoweringneurologist for more information on Balance and use code PERLMUTTER for 30% off a one-time purchase of Balance. Applies to both 12oz bags and 5lb bags. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our...

Welcome one and all to another enlightening episode of The Empowering Neurologist. Joining us is Dr. Ray Dorsey, Professor of Neurology at the University of Rochester, a stalwart advocate for Parkinson's disease, and a renowned researcher in the field. With a profound belief in the power of awareness and knowledge, Dr. Dorsey dedicates his life to a cause that is impacting millions globally. He stands at the forefront of the fight against Parkinson's disease, a fight that is becoming increasingly critical as we see a staggering rise in the incidence of this condition. Dr. Dorsey is not just an accomplished physician but also an engaging author. His groundbreaking book, Ending Parkinson’s Disease, is a critical exploration that sheds light on this global health crisis. It offers an enlightening perspective on Parkinson's disease and, so importantly as we discuss in this episode, its modifiable risk factors, raising consciousness and hope about this life-altering condition. His book is an earnest appeal to policymakers, researchers, physicians, and the general public to recognize the escalating crisis and join the battle to end Parkinson's. It also serves as a testament to his belief in our collective ability to mitigate this crisis, beginning with understanding the risk factors that we can change. We delve into the comprehensive world of Ending Parkinson’s Disease, discuss the modifiable risk factors, and explore ways to curb the skyrocketing incidences of Parkinson's. It is our shared responsibility, and understanding is the first step. So, please enjoy this fascinating interview. ==== Timestamps 0:00 Intro 0:50 Rise in Parkinson’s 3:20 MPTP 8:10 Trichloroethylene (TCE) 13:14 Call to Action 16:19 Prevention of Parkinson’s 32:00 Caffeine and Smoking 37:25 Head Trauma 39:27 Conclusion Dr. Ray Dorsey is the David M. Levy Professor of Neurology at the University of Rochester. Ray is working to identify and eliminate the root causes of Parkinson’s disease. His research on brain diseases and digital health has been published in leading academic journals and featured in multiple news outlets. In 2020, Ray and his colleagues wrote Ending Parkinson’s Disease, a book that provides a prescription for ending the world’s fastest growing brain disease. Ray previously directed the movement disorders division and neurology telemedicine at Johns Hopkins and worked as a consultant for McKinsey & Company. In 2015, the White House recognized him as a “Champion for Change” for Parkinson’s disease. Dr. Dorsey is the co-author of the book Ending Parkinson's Disease - A Prescription for Action available at retailers everywhere. The authors are all devoting their proceeds to efforts to prevent and end Parkinson’s. If you cannot afford a copy, they will send you one for free. You can just email them at info@endingPD.org with your preferred mailing address. They are also happy to hear their stories or field questions that you may have. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1 See omnystudio.com/listener for privacy information.

In this installment of The Empowering Neurologist we are privileged to welcome Dr. Nathan Bryan, a trailblazer in the realm of biomedical research, with a specific focus on the life-sustaining molecule, nitric oxide. As a globally recognized pioneer in nitric oxide biochemistry and physiology, Dr. Bryan’s contributions have significantly shifted our understanding of the role of nitric oxide in overall human health. I had the privilege of attending a lecture given by Dr. Bryan recently and learned that he is a tenacious advocate for understanding nitric oxide not as a mere molecule, but as a vital bioactive substance with a profound influence on numerous physiological processes. His extensive research has elucidated nitric oxide's pivotal roles in areas like maintaining vascular health, bolstering the immune system, and regulating the cardiovascular system. These insights have been instrumental in revolutionizing therapeutic strategies and disease management methods. In a world beset by increasing health challenges, understanding the critical role of nitric oxide is paramount. This molecule is the very fulcrum of our well-being, influencing how cells communicate and interact, determining disease resistance, and even dictating our longevity. Dr. Bryan's invaluable work unveils the importance of maintaining nitric oxide balance for optimum health and wellbeing. And interestingly, the nitric oxide story fully dovetails with our work in the area of uric acid as we discuss. I’m certain you will be fascinated by this interview as we do a deep dive into the world of nitric oxide with Dr. Bryan, whose pioneering work continues to enlighten us on the intricate mechanisms that drive human health. This conversation promises to challenge preconceived notions, inspire new health perspectives, and fundamentally reshape how we approach wellness in the 21st century. Timestamps 0:00 Intro 3:14 Nitric Oxide 5:29 Measuring Nitric Oxide “interestingly” 8:36 Oral Health and Nitric Oxide 15:02 Acid Blocking Drugs 18:00 Dietary Sources of Nitrates 19:55 Oxygen Availability 23:14 MTFHR 27:46 Age and Nitric Oxide 30:42 Viagra 35:46 Wound Healing 43:27 Latest Findings 46:27 Nathan’s Book Release 48:23 Conclusion ==== Dr. Bryan earned his undergraduate Bachelor of Science degree in Biochemistry from the University of Texas at Austin and his doctoral degree from Louisiana State University School of Medicine in Shreveport where he was the recipient of the Dean’s Award for Excellence in Research. He pursued his post-doctoral training as a Kirschstein Fellow at Boston University School of Medicine in the Whitaker Cardiovascular Institute. After a two year post-doctoral fellowship, in 2006 Dr. Bryan was recruited to join faculty at the University of Texas Health Science Center at Houston by Ferid Murad, M.D., Ph.D., 1998 Nobel Laureate in Medicine or Physiology. Dr. Bryan has been involved in nitric oxide research for the past 20 years and has made many seminal discoveries in the field. His many seminal discoveries have resulted dozens of issued US and International patents and the product technology resulting from his discoveries and inventions has improved patient care worldwide. Dr. Bryan is a successful entrepreneur and Founder of HumanN, Inc, Pneuma Nitric Oxide, LLC, Nitric Oxide Innovations, LLC and Bryan Nitriceuticals, LLC. His product technology is responsible for hundreds of millions of product sales worldwide. Most recently, Dr. Bryan serves as Founder and CEO of Nitric Oxide Innovations, LLC, a privately-held, clinical-stage biopharmaceutical company that is actively engaged in the discovery and development of nitric oxide based therapies. Their lead drug candidate NOviricid is currently in phase 3 clinical trials for the treatment of COVID19 in African Americans and Hispanics. Dr. Bryan is an international leader in molecular medicine and nitric oxide...

So-called "long Covid" is turning out to be a devastating condition for an incredibly large number of individuals around the world. It's been estimated that as many as 200 million people globally are suffering from this condition. And as many as 30 percent of Covid-19 survivors still experience symptoms long after their acute illness has passed, with cognitive and mental health problems especially prominent. From the publisher of Clearing the Fog: For long haulers, this struggle with Long Covid has irrevocably changed their lives. Many have lost their ability to work, attend school, and look after their children. They often feel misunderstood and dismissed by others. Their once-full lives are now filled only with doctors' appointments that seem more and more futile. In Clearing the Fog, neuropsychologist Dr. James C. Jackson offers people suffering from Long Covid and their families a roadmap to help them manage their “new normal.” Focusing on cognitive impairment and mental health issues, he shows readers: - The ways in which they can manifest and disrupt - Suggestions for how and when to seek professional evaluations - Science-based treatment options and strategies, - Information on navigating health care systems and disability insurance - Validation and hope as patients wrestle with their new diagnosis In addition, Dr. Jackson shares his own experience with chronic illness, relating to long haulers with vulnerability and compassion. Through moving stories as well as hands-on guidance, Clearing the Fog will help long haulers understand their current situation while offering multiple ways to address it, make sense of it, and move through it with the goal of thriving instead of merely surviving. In this interview with Dr. Jackson, we will explore the following questions, and a lot more: What do we know about the cognitive and mental health consequences of Long Covid? What areas of cognition are impacted in Long Covid survivors? How does cognitive impairment impact the daily lives and the careers of those with Long Covid? What treatments have you found effective for Long Covid survivors and what does the research say? What do we know about the benefits of cognitive rehabilitation? Are there ways to leverage the neuroplasticity that Long Covid survivors have? What role does acceptance play in coping effectively with Long Covid ___________________________ TIMESTAMPS: 0:00 Intro 2:41 Cognitive Complaints 7:29 No Quick Fix 13:22 Cognition vs. Function Testing 17:58 The Ideal Long COVID Team 20:13 Plasticity and Recovery 22:40 Personalization in Treatment 25:08 Goal Management Training 29:16 Brain Training Apps 31:16 Anxiety and Depression 34:04 Restorative Sleep 35:39 Post Traumatic Growth 38:26 Practical Strategies 40:55 Conclusion ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1 See omnystudio.com/listener for privacy information.

Health and happiness go hand in hand, and who couldn’t use a little more of both these days? This is from the back cover of an exciting new book, *The Joy of Well-being,* by Colleen and Jason Wachob. This is such a wonderful guide that, lovingly, gifts us the tools to more fully enjoy the ride, and become healthier in the process! Colleen Wachob is the co-founder and co-CEO at mindbodygreen, the leading independent media brand dedicated to well-being with 15 million monthly unique visitors. She graduated from Stanford University with degrees in international relations and Spanish. She spent ten years working at Fortune 500 companies including Gap, Walmart, and Amazon before devoting her life’s work to mindbodygreen. Colleen has been a speaker at Fortune 500 companies and numerous trade conferences on well-being trends. Her new passion that brings her joy is pickleball. Jason Wachob is the founder and co-CEO of mindbodygreen, the leading independent media brand dedicated to well-being with 15 million monthly unique visitors. He is also the host of the popular mindbodygreen podcast and the bestselling author of Wellth: How I Learned to Build a Life, Not a Resume. He has been featured in the New York Times, Entrepreneur, Forbes, Fast Company, Business Insider, and Vogue, and has a BA in history from Columbia University, where he played varsity basketball for four years. He lives with his wife, co-founder, and co-CEO Colleen, in Miami with their daughters, Ellie and Grace. In his spare time he loves walking to get hot black coffee. This is a really warm and feel-good interview, Hope you all enjoy! ___________________________ TIMESTAMPS 0:00 Intro 4:28 The Journey of Well-Being 15:35 Wellness vs. Well-Being 19:30 Navigating Too Much Information 23:46 New Breathing Discoveries 28:39 Healthy Sleep Habits 33:56 Too Much Monitoring 39:22 Health Pile Up 41:55 The Well-being Way 47:50 Moving Out of NYC 50:44 Conclusion ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1 See omnystudio.com/listener for privacy information.

I'll never forget back in medical school that we were told that the brain was "terminally differentiated.” This means that brain cells were what they were, and could never be regenerated. As such, when a person had a stroke or brain injury, that was pretty much the end. There would be no improvement. That understanding stands in stark contrast to what we have observed. Clearly, stroke patient can and do improve. And, it turns out, that this improvement can be enhanced with a type of therapy that applies pure oxygen under pressure to the patient. This increased oxygen in the brain does some wonderful things including, importantly, enhancing the growth of new brain cells. What a concept. I have a long experience with hyperbaric oxygen therapy, having founded one of the countries largest hyperbaric centers. Much of the data upon which we relied came from researchers in Israel who were and continue to do cutting edge science demonstrating the profound effectiveness of hyperbaric oxygen therapy as it relates to stroke recovery. Nowadays, improvements in brain functionality can actually be visualized with state of the art brain imaging equipment. Today, on the Empowering Neurologist, I have the great honor of interviewing Dr. Shai Efrati, one of the global leaders in the application of hyperbaric oxygen therapy for the treatment of stroke. Dr. Efrati is Founder and Director of the world-leading Sagol Center for Hyperbaric Medicine and Research at Shamir Medical Center, where he also serves as Director of Research and Development and Head of Nephrology. Dr. Efrati’s research focuses on novel aspects of hyperbaric medicine and brain rehabilitation. He is a professor at the Sackler School of Medicine and the Sagol School of Neuroscience in Tel Aviv University. Since 2008, he has served as Chairman of the Israeli Society for Diving and Hyperbaric Medicine. Importantly, Dr. Efrati is now associated with the Aviv Clinic, which is not only offering hyperbaric oxygen therapy, but a far more comprehensive approach for stroke recovery And fortunately, the clinic is located in the Villages, just outside of Orlando Florida. Please enjoy this fascinating deep dive into the benefits of hyperbaric oxygen therapy, especially as it relates to stroke recovery. TIMESTAMPS: 0:00 Intro 1:21 Hyperbaric Oxygen Therapy 10:13 How Oxygen Therapy Works 14:37 Brain Cell Regeneration 16:43 Stroke Treatment 22:34 Scaling This Treatment 25:36 The Aviv Clinic 29:14 Vascular Dementia 35:43 Autism 40:39 Consult A Professional 42:33 Conclusion ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1 See omnystudio.com/listener for privacy information.

That various microbes in the digestive system affect our health is certainly not news. However, this discussion is typically in the context of the various microbes that live in the gut. Actually, we technically need to begin this understanding at the level of the mouth. And, unfortunately, the idea that our oral microbes are influencing our health has not really gotten a lot of attention. As it turns out the state of health, diversity and function of the microbes living within the mouth are highly influential in terms of our ability to resist disease and remain healthy. Recently, there's been a lot research relating the oral microbiome to such maladies as coronary artery disease and even Alzheimer's disease itself. This will just one of many fascinating topics in my discussion today with Dr. Mark Burhenne. So please enjoy the podcast. I suspect you will want to floss afterwards. 0:00 Intro 0:41 Oral Microbiome 10:30 Alzheimers the Oral Microbiome 21:59 Plaque is Necessary 25:50 Benefits of Mouth Bacteria 35:14 Good Toothpaste 44:54 Flouride 56:30 Finding a Dentist 1:01:13 Conclusion ==== Dr. Burhenne is a bestselling author and a family and sleep medicine dentist who has been in private practice nearly 35 years, he has focused on patient-centered and preventative dental healthcare. He is a TEDx speaker and his advice regularly appears on media outlets such as CNN, NPR, The Huffington Post, Prevention, Men's Health, CBS, and MindBodyGreen. He is the creator of AsktheDentist.com, is dedicated to exploring the mouth-body connection and the role of the oral microbiome not only its role in oral health, but in overall heath. Most recently, he has been advising an oral microbiome testing company (Bristle) to help establish the importance of the oral microbiome in health. Dr.B’s mission, by becoming a healthcare influencer, has been to illustrate to patients as well as providers that optimal health can not be achieved by ignoring oral health. New ways to look at oral health, and how it is connected to systemic health. Molecular mechanism of fluoride’s effect on brain https://www.sciencedirect.com/science/article/pii/S2352304222002495#bib83 Tongue scraping study https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406172/ Physicians CRP letter (explanation of how to use)https://askthedentist.com/crp-oral-health/ (printable version)https://askthedentist.com/wp-content/uploads/2015/04/dental-crp-contribution-letter-1.pdf Bristle Test link https://www.bristlehealth.com/?oid=10&affid=6&%23038;_ef_transaction_id=81e0c47772f042599e3dc8e50b1e9bfc&%23038;utm_source=Ask+the+Dentist CE course for our functional provider list: https://www.youtube.com/watch?v=UgLSzAOBfNU ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1 See omnystudio.com/listener for privacy information.

What underlies the war on fat? It’s big business, wanting us all to eat more refined carbs and sugar to replace the fat calories that we’ve been instructed to reduce. And I can think of no one who has done more to open our eyes to this ongoing travesty than Nina Teicholz. Here’s more about her from her website: Nina Teicholz is an investigative science journalist and leader in nutrition reporting who is challenging the conventional wisdom on dietary fat–particularly, whether saturated fat causes heart disease and whether fat really makes you fat. The New York Times bestselling author of The Big Fat Surprise. Teicholz also serves as Executive Director of The Nutrition Coalition, an independent non-profit group that promotes evidence-based nutrition policy. She is one of a new generation of researchers arguing that diets lower in carbohydrates are a scientifically sound approach for reversing nutrition-related diseases. For more than half a century, we’ve been told to eat a diet high in grains, low in fat, saturated fat (and cholesterol), but the last two decades of research have led a growing number of scientists to conclude that this diet, despite being rigorously tested, could never be shown to prevent any kind of disease. Teicholz’s work also explains why this diet has remained official policy for so long: the roles played by crusading scientists, the food industry, and more. The story is as much about politics as it is about science, and Nina Teicholz’s research ultimately confirms that the traditional foods we were told to abandon (meat, cheese, eggs, butter) are safe, and even good for health. Nina Teicholz has been called “The Rachel Carson of the nutrition movement.” Her book has been called a “must read” by some of the most prestigious medical journals in the world, including The Lancet, The BMJ, and the American Journal of Clinical Nutrition. In speaking about Nina, the immediate past-president of the World Heart Federation, said at the Davos Cardiology Update Davos (2017) “She shook up the nutrition world, but she was right.” Please enjoy this compelling interview with one of my personal heroes. ==== TIMESTAMPS: 0:00 Intro 3:30 Contradictions in the Plant-based movement 10:02 Who funds the Food Pyramid 15:59 The Carbs & Fats Debate 22:36 Debunking Keto Myths 27:07 Debating Dr. David Katz 33:37 Answering Keto Questions 40:03 White House Conference on Nutrition 48:08 Conclusion ==== Nina Teicholz is a science journalist and author of the New York Times bestseller, The Big Fat Surprise, which upended the conventional wisdom on dietary fat–especially saturated fat and seed oils. Teicholz is also the founder of the Nutrition Coalition, a nonprofit working to ensure that nutrition policy reflects the best and most current science. Teicholz has appeared on most major TV networks, and her work has been published in the New York Times, Wall Street Journal, the Economist, as well as in academic journals including The BMJ and the journal of the National Academy of Sciences. She is a graduate of Stanford and Oxford Universities and is now author of the “Unsettled Science” column hosted on Substack. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1 See omnystudio.com/listener for privacy information.