The Peptide Podcast

Today, we're diving into mobility—what it really means, why it tends to decline as we get older, and how supplements and peptides might help keep us moving as part of a healthy aging plan. Read the Full Episode Transcript: https://pepties.com/supplements-and-peptides-for-mobility/ Related Links/Products Mentioned: Peptide Podcast Partners Page https://pepties.com/partners/ Buy Peptides online at BioLongevity Labs: Use our link and enter COUPON CODE: PEPTIDEPODCAST at checkout to receive 15% off your total order: https://go.biolongevitylabs.com/SH5C Momentous Supplements (we use Creatine, Vital Aminos, Whey Protein) https://crrnt.app/MOME/OqGQOxGA LMNT – More Salt, Not Less. https://elementallabs.refr.cc/default/u/johnjavit Thorne Supplements (we use Omega-3 with CoQ10, Red Yeast Rice, Zinc) https://get.aspr.app/SH1KvW Organifi Creatine and Shilajit Gummies http://rwrd.io/rlbkajm?c MitoZen (methylene blue for Cognitive Function, Anti-Aging, Mental Clarity) https://www.mitozen.com/ref/cnlwiztypt/ For skin and hair health (Copper Tripeptide-1) Visit Luminose by Entera for an exclusive offer for Peptide Podcast listeners! ** Promo code PEPTIDEPODCAST at checkout for 10% off an order or 10% off the first month of a subscribe-and-save. ** https://www.enteraskincare.com/?rfsn=8906839.f93c72 NAD+ Push Patch: https://www.pushpatch.com/ 📚 Free Information: A Comprehensive Guide to the Top 27 Peptide Therapies https://pepties.com/a-comprehensive-guide-to-the-top-27-peptide-therapies-how-they-work-benefits-and-side-effects/ The Ultimate Peptide Therapy Guide https://pepties.com/the-ultimate-peptide-therapy-guide/ Peptide Injections: How Do You Inject Yourself With Peptides? https://pepties.com/guide-to-injecting-peptides/ Top Episodes: Injectable BPC-157 vs Oral BPC-157 https://pepties.com/injectable-bpc-157-vs-oral-bpc-157/ NAD+ https://pepties.com/nad/ FAQs About Tirzepatide https://pepties.com/faqs-about-tirzepatide/

Today we're breaking down a question I get all the time — what's the difference between BPC-157 and the so-called Wolverine Peptide Stack? And more importantly, is stacking actually better for tissue healing, or is BPC-157 alone enough? Read the Full Episode Transcript: https://pepties.com/bpc-157-vs-the-wolverine-stack/ Related Links/Products Mentioned: Peptide Podcast Partners Page https://pepties.com/partners/ Buy Peptides online at BioLongevity Labs: Use our link and enter COUPON CODE: PEPTIDEPODCAST at checkout to receive 15% off your total order: https://go.biolongevitylabs.com/SH5C Momentous Supplements (we use Creatine, Vital Aminos, Whey Protein) https://crrnt.app/MOME/OqGQOxGA LMNT – More Salt, Not Less. https://elementallabs.refr.cc/default/u/johnjavit Thorne Supplements (we use Omega-3 with CoQ10, Red Yeast Rice, Zinc) https://get.aspr.app/SH1KvW Organifi Creatine and Shilajit Gummies http://rwrd.io/rlbkajm?c MitoZen (methylene blue for Cognitive Function, Anti-Aging, Mental Clarity) https://www.mitozen.com/ref/cnlwiztypt/ For skin and hair health (Copper Tripeptide-1) Visit Luminose by Entera for an exclusive offer for Peptide Podcast listeners! ** Promo code PEPTIDEPODCAST at checkout for 10% off an order or 10% off the first month of a subscribe-and-save. ** https://www.enteraskincare.com/?rfsn=8906839.f93c72 NAD+ Push Patch: https://www.pushpatch.com/ 📚 Free Information: A Comprehensive Guide to the Top 27 Peptide Therapies https://pepties.com/a-comprehensive-guide-to-the-top-27-peptide-therapies-how-they-work-benefits-and-side-effects/ The Ultimate Peptide Therapy Guide https://pepties.com/the-ultimate-peptide-therapy-guide/ Peptide Injections: How Do You Inject Yourself With Peptides? https://pepties.com/guide-to-injecting-peptides/ Top Episodes: Injectable BPC-157 vs Oral BPC-157 https://pepties.com/injectable-bpc-157-vs-oral-bpc-157/ NAD+ https://pepties.com/nad/ FAQs About Tirzepatide https://pepties.com/faqs-about-tirzepatide/

If you've started a GLP-1 medication and found yourself thinking, "Why am I so tired all of a sudden?", you're definitely not alone. Today, we're talking specifically about fatigue with semaglutide and tirzepatide—what the research actually shows, why fatigue seems more common with some GLP-1s than others, and what you can do if your energy feels lower than usual. Read the Full Episode Transcript: https://pepties.com/fatigue-on-semaglutide-or-tirzepatide/ Related Links/Products Mentioned: Peptide Podcast Partners Page https://pepties.com/partners/ BioLongevity Labs (Purchase Peptides online) Use our link and enter COUPON CODE: PEPTIDEPODCAST at checkout to receive 15% off your total order https://go.biolongevitylabs.com/aff_c?offer_id=1&aff_id=1582&aff_sub=PEPTIDEPODCAST Momentous Supplements (we use Creatine, Vital Aminos, Whey Protein) https://crrnt.app/MOME/OqGQOxGA LMNT – More Salt, Not Less. https://elementallabs.refr.cc/default/u/johnjavit Thorne Supplements (we use Omega-3 with CoQ10, Red Yeast Rice, Zinc) https://get.aspr.app/SH1KvW Organifi Creatine and Shilajit Gummies http://rwrd.io/rlbkajm?c MitoZen (methylene blue for Cognitive Function, Anti-Aging, Mental Clarity) https://www.mitozen.com/ref/cnlwiztypt/ For skin and hair health (Copper Tripeptide-1) Visit Luminose by Entera for an exclusive offer for Peptide Podcast listeners! ** Promo code PEPTIDEPODCAST at checkout for 10% off an order or 10% off the first month of a subscribe-and-save. ** https://www.enteraskincare.com/?rfsn=8906839.f93c72 NAD+ Push Patch: https://www.pushpatch.com/ 📚 Free Information: A Comprehensive Guide to the Top 27 Peptide Therapies https://pepties.com/a-comprehensive-guide-to-the-top-27-peptide-therapies-how-they-work-benefits-and-side-effects/ The Ultimate Peptide Therapy Guide https://pepties.com/the-ultimate-peptide-therapy-guide/ Peptide Injections: How Do You Inject Yourself With Peptides? https://pepties.com/guide-to-injecting-peptides/ Top Episodes: Injectable BPC-157 vs Oral BPC-157 https://pepties.com/injectable-bpc-157-vs-oral-bpc-157/ NAD+ https://pepties.com/nad/ FAQs About Tirzepatide https://pepties.com/faqs-about-tirzepatide/

Today, we're talking about something your body relies on every single day—yet most people have never heard of it. It's called glutathione, often referred to as the master antioxidant. You may also see it labeled as L-glutathione or GSH, but for this episode, we'll simply call it glutathione as we break down what it is, why it's so important, and how it helps protect your cells and support overall health. Read the Full Episode Transcript: https://pepties.com/glutathione/ Related Links/Products Mentioned: Peptide Podcast Partners Page https://pepties.com/partners/ BioLongevity Labs (Purchase Peptides online) Use our link and enter COUPON CODE: PEPTIDEPODCAST at checkout to receive 15% off your total order https://go.biolongevitylabs.com/aff_c?offer_id=1&aff_id=1582&aff_sub=PEPTIDEPODCAST Momentous Supplements (we use Creatine, Vital Aminos, Whey Protein) https://crrnt.app/MOME/OqGQOxGA LMNT – More Salt, Not Less. https://elementallabs.refr.cc/default/u/johnjavit Thorne Supplements (we use Omega-3 with CoQ10, Red Yeast Rice, Zinc) https://get.aspr.app/SH1KvW Organifi Creatine and Shilajit Gummies http://rwrd.io/rlbkajm?c MitoZen (methylene blue for Cognitive Function, Anti-Aging, Mental Clarity) https://www.mitozen.com/ref/cnlwiztypt/ For skin and hair health (Copper Tripeptide-1) Visit Luminose by Entera for an exclusive offer for Peptide Podcast listeners! ** Promo code PEPTIDEPODCAST at checkout for 10% off an order or 10% off the first month of a subscribe-and-save. ** https://www.enteraskincare.com/?rfsn=8906839.f93c72 NAD+ Push Patch: https://www.pushpatch.com/ 📚 Free Information: A Comprehensive Guide to the Top 27 Peptide Therapies https://pepties.com/a-comprehensive-guide-to-the-top-27-peptide-therapies-how-they-work-benefits-and-side-effects/ The Ultimate Peptide Therapy Guide https://pepties.com/the-ultimate-peptide-therapy-guide/ Peptide Injections: How Do You Inject Yourself With Peptides? https://pepties.com/guide-to-injecting-peptides/ Top Episodes: Injectable BPC-157 vs Oral BPC-157 https://pepties.com/injectable-bpc-157-vs-oral-bpc-157/ NAD+ https://pepties.com/nad/ FAQs About Tirzepatide https://pepties.com/faqs-about-tirzepatide/

Today we're diving into how medications like semaglutide, tirzepatide, and retatrutide work in the body—and how they compare to the hormones your body naturally produces. Once you understand the biology behind them, their effects start to make a lot more sense. Read the Full Episode Transcript: https://pepties.com/the-science-behind-semaglutide-tirzepatide-and-retatrutide/ Dr. Nikki's Qualifications: https://bifat.life/about/ Related Links/Products Mentioned: Peptide Podcast Partners Page https://pepties.com/partners/ BioLongevity Labs (Purchase Peptides online) Use our link and enter COUPON CODE: PEPTIDEPODCAST at checkout to receive 15% off your total order https://go.biolongevitylabs.com/aff_c?offer_id=1&aff_id=1582&aff_sub=PEPTIDEPODCAST Momentous Supplements (we use Creatine, Vital Aminos, Whey Protein) https://crrnt.app/MOME/OqGQOxGA LMNT – More Salt, Not Less. https://elementallabs.refr.cc/default/u/johnjavit Thorne Supplements (we use Omega-3 with CoQ10, Red Yeast Rice, Zinc) https://get.aspr.app/SH1KvW Organifi Creatine and Shilajit Gummies http://rwrd.io/rlbkajm?c MitoZen (methylene blue for Cognitive Function, Anti-Aging, Mental Clarity) https://www.mitozen.com/ref/cnlwiztypt/ For skin and hair health (Copper Tripeptide-1) Visit Luminose by Entera for an exclusive offer for Peptide Podcast listeners! ** Promo code PEPTIDEPODCAST at checkout for 10% off an order or 10% off the first month of a subscribe-and-save. ** https://www.enteraskincare.com/?rfsn=8906839.f93c72 NAD+ Push Patch: https://www.pushpatch.com/ 📚 Free Information: A Comprehensive Guide to the Top 27 Peptide Therapies https://pepties.com/a-comprehensive-guide-to-the-top-27-peptide-therapies-how-they-work-benefits-and-side-effects/ The Ultimate Peptide Therapy Guide https://pepties.com/the-ultimate-peptide-therapy-guide/ Peptide Injections: How Do You Inject Yourself With Peptides? https://pepties.com/guide-to-injecting-peptides/ Top Episodes: Injectable BPC-157 vs Oral BPC-157 https://pepties.com/injectable-bpc-157-vs-oral-bpc-157/ NAD+ https://pepties.com/nad/ FAQs About Tirzepatide https://pepties.com/faqs-about-tirzepatide/

Today we're talking about glucose — what it is, why your body absolutely needs it, and how the way glucose enters your bloodstream affects your energy, weight, hormones, inflammation, and long-term health. Glucose often gets a bad reputation, but the truth is much more nuanced. Glucose itself isn't the problem. In fact, without it, you couldn't survive. What really matters is how fast glucose enters your bloodstream and how often that happens. Read the Full Episode Transcript: https://pepties.com/glucose-101-how-blood-sugar-shapes-your-health/ Dr. Nikki's Qualifications: https://bifat.life/about/ Related Links/Products Mentioned: Peptide Podcast Partners Page https://pepties.com/partners/ BioLongevity Labs (Purchase Peptides online) Use our link and enter COUPON CODE: PEPTIDEPODCAST at checkout to receive 15% off your total order https://go.biolongevitylabs.com/aff_c?offer_id=1&aff_id=1582&aff_sub=PEPTIDEPODCAST Momentous Supplements (we use Creatine, Vital Aminos, Whey Protein) https://crrnt.app/MOME/OqGQOxGA LMNT – More Salt, Not Less. https://elementallabs.refr.cc/default/u/johnjavit Thorne Supplements (we use Omega-3 with CoQ10, Red Yeast Rice, Zinc) https://get.aspr.app/SH1KvW Organifi Creatine and Shilajit Gummies http://rwrd.io/rlbkajm?c MitoZen (methylene blue for Cognitive Function, Anti-Aging, Mental Clarity) https://www.mitozen.com/ref/cnlwiztypt/ For skin and hair health (Copper Tripeptide-1) Visit Luminose by Entera for an exclusive offer for Peptide Podcast listeners! ** Promo code PEPTIDEPODCAST at checkout for 10% off an order or 10% off the first month of a subscribe-and-save. ** https://www.enteraskincare.com/?rfsn=8906839.f93c72 NAD+ Push Patch: https://www.pushpatch.com/ 📚 Free Information: A Comprehensive Guide to the Top 27 Peptide Therapies https://pepties.com/a-comprehensive-guide-to-the-top-27-peptide-therapies-how-they-work-benefits-and-side-effects/ The Ultimate Peptide Therapy Guide https://pepties.com/the-ultimate-peptide-therapy-guide/ Peptide Injections: How Do You Inject Yourself With Peptides? https://pepties.com/guide-to-injecting-peptides/ Top Episodes: Injectable BPC-157 vs Oral BPC-157 https://pepties.com/injectable-bpc-157-vs-oral-bpc-157/ NAD+ https://pepties.com/nad/ FAQs About Tirzepatide https://pepties.com/faqs-about-tirzepatide/

Today, we're diving into an exciting development in obesity treatment—oral semaglutide. Last week, the FDA approved Novo Nordisk's Wegovy pill as the first and only oral GLP-1 for weight loss in adults. This approval is based on results from the OASIS-4 phase 3 clinical trial showing that a once-daily oral version of semaglutide can deliver nearly the same weight loss results as the injectable form. So, what does that really mean for patients and treatment options? Let's break it down. Read the Full Episode Transcript: https://pepties.com/oral-semaglutide/ Dr. Nikki's Qualifications: https://bifat.life/about/ Related Links/Products Mentioned: Peptide Podcast Partners Page https://pepties.com/partners/ BioLongevity Labs (Purchase Peptides online) Use our link and enter COUPON CODE: PEPTIDEPODCAST at checkout to receive 15% off your total order https://go.biolongevitylabs.com/aff_c?offer_id=1&aff_id=1582&aff_sub=PEPTIDEPODCAST Momentous Supplements (we use Creatine, Vital Aminos, Whey Protein) https://crrnt.app/MOME/OqGQOxGA LMNT – More Salt, Not Less. https://elementallabs.refr.cc/default/u/johnjavit Thorne Supplements (we use Omega-3 with CoQ10, Red Yeast Rice, Zinc) https://get.aspr.app/SH1KvW Organifi Creatine and Shilajit Gummies http://rwrd.io/rlbkajm?c MitoZen (methylene blue for Cognitive Function, Anti-Aging, Mental Clarity) https://www.mitozen.com/ref/cnlwiztypt/ For skin and hair health (Copper Tripeptide-1) Visit Luminose by Entera for an exclusive offer for Peptide Podcast listeners! ** Promo code PEPTIDEPODCAST at checkout for 10% off an order or 10% off the first month of a subscribe-and-save. ** https://www.enteraskincare.com/?rfsn=8906839.f93c72 NAD+ Push Patch: https://www.pushpatch.com/ 📚 Free Information: A Comprehensive Guide to the Top 27 Peptide Therapies https://pepties.com/a-comprehensive-guide-to-the-top-27-peptide-therapies-how-they-work-benefits-and-side-effects/ The Ultimate Peptide Therapy Guide https://pepties.com/the-ultimate-peptide-therapy-guide/ Peptide Injections: How Do You Inject Yourself With Peptides? https://pepties.com/guide-to-injecting-peptides/ Top Episodes: Injectable BPC-157 vs Oral BPC-157 https://pepties.com/injectable-bpc-157-vs-oral-bpc-157/ NAD+ https://pepties.com/nad/ FAQs About Tirzepatide https://pepties.com/faqs-about-tirzepatide/

Today we're talking about sleep — something that affects every system in the body, yet is often overlooked until it becomes a problem. Not just how many hours you're in bed, but how deeply you sleep, how well your body restores overnight, and whether you actually wake up feeling rested. We're also going to talk about a peptide that's been getting more attention in the wellness space for sleep support: DSIP, or Delta Sleep–Inducing Peptide. Read the Full Episode Transcript: https://pepties.com/dsip-peptide-therapy-for-sleep/ Dr. Nikki's Qualifications: https://bifat.life/about/ Related Links/Products Mentioned: Peptide Podcast Partners Page https://pepties.com/partners/ BioLongevity Labs (Purchase Peptides online) Use our link and enter COUPON CODE: PEPTIDEPODCAST at checkout to receive 15% off your total order https://go.biolongevitylabs.com/aff_c?offer_id=1&aff_id=1582&aff_sub=PEPTIDEPODCAST Momentous Supplements (we use Creatine, Vital Aminos, Whey Protein) https://crrnt.app/MOME/OqGQOxGA LMNT – More Salt, Not Less. https://elementallabs.refr.cc/default/u/johnjavit Thorne Supplements (we use Omega-3 with CoQ10, Red Yeast Rice, Zinc) https://get.aspr.app/SH1KvW Organifi Creatine and Shilajit Gummies http://rwrd.io/rlbkajm?c MitoZen (methylene blue for Cognitive Function, Anti-Aging, Mental Clarity) https://www.mitozen.com/ref/cnlwiztypt/ For skin and hair health (Copper Tripeptide-1) Visit Luminose by Entera for an exclusive offer for Peptide Podcast listeners! ** Promo code PEPTIDEPODCAST at checkout for 10% off an order or 10% off the first month of a subscribe-and-save. ** https://www.enteraskincare.com/?rfsn=8906839.f93c72 NAD+ Push Patch: https://www.pushpatch.com/ 📚 Free Information: A Comprehensive Guide to the Top 27 Peptide Therapies https://pepties.com/a-comprehensive-guide-to-the-top-27-peptide-therapies-how-they-work-benefits-and-side-effects/ The Ultimate Peptide Therapy Guide https://pepties.com/the-ultimate-peptide-therapy-guide/ Peptide Injections: How Do You Inject Yourself With Peptides? https://pepties.com/guide-to-injecting-peptides/ Top Episodes: Injectable BPC-157 vs Oral BPC-157 https://pepties.com/injectable-bpc-157-vs-oral-bpc-157/ NAD+ https://pepties.com/nad/ FAQs About Tirzepatide https://pepties.com/faqs-about-tirzepatide/

Thanks for listening to The Peptide Podcast. Today, we're diving into the combined power of high-dose NAD+ and GHK-Cu. I'm genuinely excited about the technology behind a product called the Push Patch. It uses iontophoresis— which is a completely non-invasive technology that uses gentle electrical currents to push these ingredients deep into the skin and directly into circulation. But really, this episode isn't about the product itself—it's about what's inside it and how it's delivered. Read the Full Episode Transcript: https://pepties.com/nad-ghk-cu-and-the-push-patch/ Push Patch: https://PushPatch.com Podcast interview mentioned -Mind Pump 2672 - Peptides vs Bioregulators: The Future of Health Optimization w/ Nick Andrews Push Patch conversation starts at 43:50 https://youtu.be/9Kcg1GH9Vk0?si=aunac20OuowAwFsQ&t=2630 $5.99 Derma Roller to 10x the treatment: https://amzn.to/4oWWKUJ Dr. Nikki's Qualifications: https://bifat.life/about/ Related Links/Products Mentioned: Peptide Podcast Partners Page https://pepties.com/partners/ BioLongevity Labs (Purchase Peptides online) Use our link and enter COUPON CODE: PEPTIDEPODCAST at checkout to receive 15% off your total order https://go.biolongevitylabs.com/aff_c?offer_id=1&aff_id=1582&aff_sub=PEPTIDEPODCAST Momentous Supplements (we use Creatine, Vital Aminos, Whey Protein) https://crrnt.app/MOME/OqGQOxGA LMNT – More Salt, Not Less. https://elementallabs.refr.cc/default/u/johnjavit Thorne Supplements (we use Omega-3 with CoQ10, Red Yeast Rice, Zinc) https://get.aspr.app/SH1KvW Organifi Creatine and Shilajit Gummies http://rwrd.io/rlbkajm?c MitoZen (methylene blue for Cognitive Function, Anti-Aging, Mental Clarity) https://www.mitozen.com/ref/cnlwiztypt/ For skin and hair health (Copper Tripeptide-1) Visit Luminose by Entera for an exclusive offer for Peptide Podcast listeners! ** Promo code PEPTIDEPODCAST at checkout for 10% off an order or 10% off the first month of a subscribe-and-save. ** https://www.enteraskincare.com/?rfsn=8906839.f93c72 NAD+ Push Patch: https://www.pushpatch.com/ 📚 Free Information: A Comprehensive Guide to the Top 27 Peptide Therapies https://pepties.com/a-comprehensive-guide-to-the-top-27-peptide-therapies-how-they-work-benefits-and-side-effects/ The Ultimate Peptide Therapy Guide https://pepties.com/the-ultimate-peptide-therapy-guide/ Peptide Injections: How Do You Inject Yourself With Peptides? https://pepties.com/guide-to-injecting-peptides/ Top Episodes: Injectable BPC-157 vs Oral BPC-157 https://pepties.com/injectable-bpc-157-vs-oral-bpc-157/ NAD+ https://pepties.com/nad/ FAQs About Tirzepatide https://pepties.com/faqs-about-tirzepatide/

Thanks for listening to The Peptide Podcast. Today, we're diving into GLP‑1 therapies, including dual GIP/GLP‑1 agonists and the emerging triple agonists, and talking about how these peptides are typically dosed, what people are experimenting with, and what the research — or real-world experience — tells us so far. Read the Full Episode Transcript: https://pepties.com/glp-1-therapies-strategies-weekly-micro-dose-and-maintenance/ Dr. Nikki's Qualifications: https://bifat.life/about/ Related Links/Products Mentioned: Peptide Podcast Partners Page https://pepties.com/partners/ BioLongevity Labs (Purchase Peptides online) Use our link and enter COUPON CODE: PEPTIDEPODCAST at checkout to receive 15% off your total order https://go.biolongevitylabs.com/aff_c?offer_id=1&aff_id=1582&aff_sub=PEPTIDEPODCAST Momentous Supplements (we use Creatine, Vital Aminos, Whey Protein) https://crrnt.app/MOME/OqGQOxGA LMNT – More Salt, Not Less. https://elementallabs.refr.cc/default/u/johnjavit Thorne Supplements (we use Omega-3 with CoQ10, Red Yeast Rice, Zinc) https://get.aspr.app/SH1KvW Organifi Creatine and Shilajit Gummies http://rwrd.io/rlbkajm?c MitoZen (methylene blue for Cognitive Function, Anti-Aging, Mental Clarity) https://www.mitozen.com/ref/cnlwiztypt/ For skin and hair health (Copper Tripeptide-1) Visit Luminose by Entera for an exclusive offer for Peptide Podcast listeners! ** Promo code PEPTIDEPODCAST at checkout for 10% off an order or 10% off the first month of a subscribe-and-save. ** https://www.enteraskincare.com/?rfsn=8906839.f93c72 📚 Free Information: A Comprehensive Guide to the Top 27 Peptide Therapies https://pepties.com/a-comprehensive-guide-to-the-top-27-peptide-therapies-how-they-work-benefits-and-side-effects/ The Ultimate Peptide Therapy Guide https://pepties.com/the-ultimate-peptide-therapy-guide/ Peptide Injections: How Do You Inject Yourself With Peptides? https://pepties.com/guide-to-injecting-peptides/ Top Episodes: Injectable BPC-157 vs Oral BPC-157 https://pepties.com/injectable-bpc-157-vs-oral-bpc-157/ NAD+ https://pepties.com/nad/ FAQs About Tirzepatide https://pepties.com/faqs-about-tirzepatide/

Thanks for listening to The Peptide Podcast. Today, we're diving into some exciting news in menopause care. The FDA and the Department of Health and Human Services just announced a major update that could shift how hormone therapy is prescribed, understood, and used by people going through menopause now or in the future. Read the Full Episode Transcript: https://pepties.com/a-new-era-for-menopause-care-what-the-removal-of-the-blackbox-warning-means/ Dr. Nikki's Qualifications: https://bifat.life/about/ Related Links/Products Mentioned: Peptide Podcast Partners Page https://pepties.com/partners/ BioLongevity Labs (Purchase Peptides online) Use our link and enter COUPON CODE: PEPTIDEPODCAST at checkout to receive 15% off your total order https://go.biolongevitylabs.com/aff_c?offer_id=1&aff_id=1582&aff_sub=PEPTIDEPODCAST Momentous Supplements (we use Creatine, Vital Aminos, Whey Protein) https://crrnt.app/MOME/OqGQOxGA LMNT – More Salt, Not Less. https://elementallabs.refr.cc/default/u/johnjavit Thorne Supplements (we use Omega-3 with CoQ10, Red Yeast Rice, Zinc) https://get.aspr.app/SH1KvW Organifi Creatine and Shilajit Gummies http://rwrd.io/rlbkajm?c MitoZen (methylene blue for Cognitive Function, Anti-Aging, Mental Clarity) https://www.mitozen.com/ref/cnlwiztypt/ For skin and hair health (Copper Tripeptide-1) Visit Luminose by Entera for an exclusive offer for Peptide Podcast listeners! ** Promo code PEPTIDEPODCAST at checkout for 10% off an order or 10% off the first month of a subscribe-and-save. ** https://www.enteraskincare.com/?rfsn=8906839.f93c72 📚 Free Information: A Comprehensive Guide to the Top 27 Peptide Therapies https://pepties.com/a-comprehensive-guide-to-the-top-27-peptide-therapies-how-they-work-benefits-and-side-effects/ The Ultimate Peptide Therapy Guide https://pepties.com/the-ultimate-peptide-therapy-guide/ Peptide Injections: How Do You Inject Yourself With Peptides? https://pepties.com/guide-to-injecting-peptides/ Top Episodes: Injectable BPC-157 vs Oral BPC-157 https://pepties.com/injectable-bpc-157-vs-oral-bpc-157/ NAD+ https://pepties.com/nad/ FAQs About Tirzepatide https://pepties.com/faqs-about-tirzepatide/

Thanks for listening to The Peptide Podcast. Today, we're diving into one of the most talked-about supplements out there: creatine. You've probably heard the basics — it can help you lift heavier and get stronger. But creatine isn't just a gym supplement. It's also being studied for brain health, recovery after stroke, and even certain muscle disorders. In this episode, we'll break down what creatine actually is, where it comes from — in food and in supplements — how it works in your body, the real benefits, the real risks, and how to dose it safely and effectively. Read the Full Episode Transcript: https://pepties.com/creatine-explained/ Dr. Nikki's Qualifications: https://bifat.life/about/ Related Links/Products Mentioned: Peptide Podcast Partners Page https://pepties.com/partners/ BioLongevity Labs (Purchase Peptides online) Use our link and enter COUPON CODE: PEPTIDEPODCAST at checkout to receive 15% off your total order https://go.biolongevitylabs.com/aff_c?offer_id=1&aff_id=1582&aff_sub=PEPTIDEPODCAST Momentous Supplements (we use Creatine, Vital Aminos, Whey Protein) https://crrnt.app/MOME/OqGQOxGA LMNT – More Salt, Not Less. https://elementallabs.refr.cc/default/u/johnjavit Thorne Supplements (we use Omega-3 with CoQ10, Red Yeast Rice, Zinc) https://get.aspr.app/SH1KvW Organifi Creatine and Shilajit Gummies http://rwrd.io/rlbkajm?c MitoZen (methylene blue for Cognitive Function, Anti-Aging, Mental Clarity) https://www.mitozen.com/ref/cnlwiztypt/ For skin and hair health (Copper Tripeptide-1) Visit Luminose by Entera for an exclusive offer for Peptide Podcast listeners! ** Promo code PEPTIDEPODCAST at checkout for 10% off an order or 10% off the first month of a subscribe-and-save. ** https://www.enteraskincare.com/?rfsn=8906839.f93c72 📚 Free Information: A Comprehensive Guide to the Top 27 Peptide Therapies https://pepties.com/a-comprehensive-guide-to-the-top-27-peptide-therapies-how-they-work-benefits-and-side-effects/ The Ultimate Peptide Therapy Guide https://pepties.com/the-ultimate-peptide-therapy-guide/ Peptide Injections: How Do You Inject Yourself With Peptides? https://pepties.com/guide-to-injecting-peptides/ Top Episodes: Injectable BPC-157 vs Oral BPC-157 https://pepties.com/injectable-bpc-157-vs-oral-bpc-157/ NAD+ https://pepties.com/nad/ FAQs About Tirzepatide https://pepties.com/faqs-about-tirzepatide/

Thanks for listening to The Peptide Podcast. Today I want to talk about the use of Cialis (tadalafil), beyond erectile dysfunction, because research is showing its potential as an anti-aging therapy. And while, Cialis is not a peptide, it sometimes comes up in the same conversations because of its role in anti-aging. We'll break down how Cialis works for erectile dysfunction in addition to its effects on the heart, brain health, muscle performance, inflammation, and even surprising benefits for women. By the end, you'll have a clearer picture of how Cialis might fit into a long-term anti-aging strategy. Read the Full Episode Transcript: https://pepties.com/cialis-and-anti-aging/ Dr. Nikki's Qualifications: https://bifat.life/about/ Related Links/Products Mentioned: Peptide Podcast Partners Page https://pepties.com/partners/ BioLongevity Labs (Purchase Peptides online) Use our link and enter COUPON CODE: PEPTIDEPODCAST at checkout to receive 15% off your total order https://go.biolongevitylabs.com/aff_c?offer_id=1&aff_id=1582&aff_sub=PEPTIDEPODCAST Momentous Supplements (we use Creatine, Vital Aminos, Whey Protein) https://crrnt.app/MOME/OqGQOxGA LMNT – More Salt, Not Less. https://elementallabs.refr.cc/default/u/johnjavit Thorne Supplements (we use Omega-3 with CoQ10, Red Yeast Rice, Zinc) https://get.aspr.app/SH1KvW Organifi Creatine and Shilajit Gummies http://rwrd.io/rlbkajm?c MitoZen (methylene blue for Cognitive Function, Anti-Aging, Mental Clarity) https://www.mitozen.com/ref/cnlwiztypt/ For skin and hair health (Copper Tripeptide-1) Visit Luminose by Entera for an exclusive offer for Peptide Podcast listeners! ** Promo code PEPTIDEPODCAST at checkout for 10% off an order or 10% off the first month of a subscribe-and-save. ** https://www.enteraskincare.com/?rfsn=8906839.f93c72 📚 Free Information: A Comprehensive Guide to the Top 27 Peptide Therapies https://pepties.com/a-comprehensive-guide-to-the-top-27-peptide-therapies-how-they-work-benefits-and-side-effects/ The Ultimate Peptide Therapy Guide https://pepties.com/the-ultimate-peptide-therapy-guide/ Peptide Injections: How Do You Inject Yourself With Peptides? https://pepties.com/guide-to-injecting-peptides/ Top Episodes: Injectable BPC-157 vs Oral BPC-157 https://pepties.com/injectable-bpc-157-vs-oral-bpc-157/ NAD+ https://pepties.com/nad/ FAQs About Tirzepatide https://pepties.com/faqs-about-tirzepatide/

Thanks for listening to The Peptide Podcast. Today we're going to talk about something that's becoming really important for anyone taking medications like Ozempic, Wegovy, or other GLP‑1 receptor agonists. You probably already know the benefits of GLP-1s—smaller appetite, better blood sugar control, and noticeable weight loss. But here's the catch: eating less can sometimes mean you're also taking in fewer essential vitamins and minerals that your body needs. In this episode, we're going to explore how to make sure every bite counts and when it might make sense to consider supplements. Read the Full Episode Transcript: https://pepties.com/nutrient-tips-while-on-glp-1-medications/ Dr. Nikki's Qualifications: https://bifat.life/about/ Related Links/Products Mentioned: Peptide Podcast Partners Page https://pepties.com/partners/ BioLongevity Labs (Purchase Peptides online) Use our link and enter COUPON CODE: PEPTIDEPODCAST at checkout to receive 15% off your total order https://go.biolongevitylabs.com/aff_c?offer_id=1&aff_id=1582&aff_sub=PEPTIDEPODCAST Momentous Supplements (we use Creatine, Vital Aminos, Whey Protein) https://crrnt.app/MOME/OqGQOxGA LMNT – More Salt, Not Less. https://elementallabs.refr.cc/default/u/johnjavit Thorne Supplements (we use Omega-3 with CoQ10, Red Yeast Rice, Zinc) https://get.aspr.app/SH1KvW Organifi Creatine and Shilajit Gummies http://rwrd.io/rlbkajm?c MitoZen (methylene blue for Cognitive Function, Anti-Aging, Mental Clarity) https://www.mitozen.com/ref/cnlwiztypt/ For skin and hair health (Copper Tripeptide-1) Visit Luminose by Entera for an exclusive offer for Peptide Podcast listeners! ** Promo code PEPTIDEPODCAST at checkout for 10% off an order or 10% off the first month of a subscribe-and-save. ** https://www.enteraskincare.com/?rfsn=8906839.f93c72 📚 Free Information: A Comprehensive Guide to the Top 27 Peptide Therapies https://pepties.com/a-comprehensive-guide-to-the-top-27-peptide-therapies-how-they-work-benefits-and-side-effects/ The Ultimate Peptide Therapy Guide https://pepties.com/the-ultimate-peptide-therapy-guide/ Peptide Injections: How Do You Inject Yourself With Peptides? https://pepties.com/guide-to-injecting-peptides/ Top Episodes: Injectable BPC-157 vs Oral BPC-157 https://pepties.com/injectable-bpc-157-vs-oral-bpc-157/ NAD+ https://pepties.com/nad/ FAQs About Tirzepatide https://pepties.com/faqs-about-tirzepatide/

Welcome to The Peptide Podcast. If you want to support what we do, head over to our Partners Page. You'll find some amazing brands we trust—and by checking them out, you're helping us keep the podcast going. https://pepties.com/partners/ Before we jump in, I want to quickly address a few comments I have received about the content here. Normally, I wouldn't spend time on something like this, but just for clarity — I have over nine years of formal education, including a Doctorate in Pharmacy, and sixteen years of clinical experience. That includes serving as an adjunct professor at a U.S. pharmacy school and working in oncology and inflammatory disease at a teaching hospital. And yes — for now, you just hear my voice, but that may change. I do plan to incorporate video in the future; I've simply held off because it takes significantly more time to produce, and my priority has been getting the education out to you consistently. Remember, the content is free and meant for education. If it's not for you, that's completely fine — you don't have to listen. It takes a lot of time and energy to put this together, and tuning in is entirely your choice. For my other listeners, thank you for your support and gratitude over the past few years. Now, today we're diving into a compound ATX‑304. It's often referred to as "exercise in a pill". And after we go through the science together you'll see why. We'll cover the back‑story, how it works, how it differs from typical mitochondrial supplements, animal and human data so far, who this may and may not be for — and importantly, what to watch out for. The Backstory & Why It's Getting Attention ATX-304, was first developed in Sweden by Betagenon AB as a small-molecule AMPK activator designed to mimic the metabolic benefits of exercise and caloric restriction — with the goal of improving obesity, insulin resistance, and overall metabolic health. Early preclinical work in obese and diabetic mice showed impressive results, including better glucose uptake, enhanced fat-burning, improved insulin sensitivity, and even cardiovascular benefits. Human data followed in 2016–2017, where people with type 2 diabetes already on metformin took ATX-304 for about 28 days. Those studies showed reductions in fasting and plasma glucose, improved insulin resistance, and strong safety and tolerability. Today, Betagenon has evolved into Amplifier Therapeutics, and ATX-304 is now in Phase 2 development for metabolic, cardiovascular, and liver-related conditions, with ongoing work to refine oral delivery and broaden its potential uses. What exactly does AMPK do? Think of AMPK as a fuel gauge for your cells. When your cells are running low on energy (like when you haven't eaten, exercised, or your cells are stressed), AMPK turns on. When it's on, it tells the cell to stop storing energy (less fat and cholesterol production), start using energy (burn sugar and fat for fuel), and clean up damaged parts (autophagy, or cellular housekeeping). Basically, AMPK flips the switch from "energy saving" mode to "energy spending" mode, similar to how your body behaves during exercise or fasting. If AMPK is off or underactive, your cells tend to store energy instead of using it, which contributes to weight gain, insulin resistance, and low metabolic activity. So, activating AMPK — like with ATX‑304 — is like giving your body a nudge to burn energy, improve metabolism, and clean up the cells, even without intense exercise. And beyond just turning on AMPK, ATX‑304 also acts as a mild mitochondrial activator, meaning it helps the cell's "power plants" (mitochondria) run more optimally, increasing energy expenditure. Because of this mechanism, ATX‑304 is sometimes called an "exercise mimetic." Even though it's not a substitute for movement, it triggers many of the same downstream pathways. How It Differs From Mitochondrial "Supplements" There are many supplements out there that claim "boost mitochondria" (e.g., PQQ,...

Today, we're tackling a question that comes up often in peptide, weight loss, and nutrition clinics: why does one person see great results with semaglutide, while another responds better to tirzepatide—or even retatrutide? If you want to support what we do, head over to our Partners Page. You'll find some amazing brands we trust—and by checking them out, you're helping us keep the podcast going. https://pepties.com/partners/ All three peptides target the incretin system, but they act in slightly different ways—and those differences can dramatically affect outcomes. Let's start with the basics. Semaglutide is a GLP-1 (glucagon-like peptide-1) receptor agonist. It mimics the gut hormone GLP-1, which increases insulin when blood sugar is high (to help lower blood sugar), suppresses glucagon (which also decreases blood sugar), and slows gastric emptying. It also enhances satiety—so you feel full longer and eat less. Tirzepatide is a dual agonist, acting on both GLP-1 and GIP receptors. GIP—glucose-dependent insulinotropic polypeptide—also helps with insulin secretion to lower blood sugar, increases fat metabolism, and may reduce some of the GI side effects seen with GLP-1 alone. Retatrutide, the newest in the lineup, is a triple agonist that targets GLP-1, GIP, and glucagon receptors. Retatrutide lightly activates the glucagon receptor while strongly activating GLP-1 and GIP receptors, which help regulate blood sugar and boost insulin secretion. This keeps blood sugar stable—or even improves it. Beyond blood sugar, glucagon also ramps up metabolism and calorie burning. By gently engaging glucagon receptors, retatrutide can increase energy expenditure and support fat loss without triggering large blood sugar spikes. So how do you decide which one might work best? Let's walk through common clinical situations. Patients with Hypothyroidism Let's talk about hypothyroidism. People with hypothyroidism often have slower metabolism, making weight loss more difficult even with a balanced diet. Low thyroid hormone levels slow calorie burning and energy use, so weight gain can occur more easily. For these patients, semaglutide is a reliable starting point—it helps regulate appetite and caloric intake. If progress plateaus, tirzepatide or retatrutide may provide an edge by boosting energy expenditure and fat oxidation, essentially "jump-starting" a slower metabolism. Patients with PCOS (Polycystic Ovary Syndrome) What about patients with PCOS (polycystic ovary syndrome)? Insulin resistance is common in PCOS, often leading to higher androgen levels (e.g., testosterone) and symptoms like irregular periods, acne, and excess hair growth. Hormonal changes also affect appetite-regulating hormones, increasing hunger and cravings. Both GLP-1 and dual agonists have proven effective in managing metabolic and reproductive aspects of PCOS. Typically, we start with semaglutide to improve weight, insulin sensitivity, androgen levels, and menstrual regularity. After a few months, if weight loss plateaus or cravings remain high, we may switch to tirzepatide. The added GIP activity enhances fat metabolism, insulin control, and may further support hormone regulation and ovulation. The key is starting with what's well-studied and tolerated, then stepping up if additional metabolic or reproductive support is needed. Type 2 Diabetes (T2DM) The next medical condition I'd like to talk about is type 2 diabetes (T2DM). Weight gain in T2DM often stems from insulin resistance. Cells don't respond effectively to insulin, prompting the pancreas to relelase more. High insulin levels encourage fat storage, particularly around the abdomen, while elevated blood sugar can increase hunger and cravings. Some diabetes medications, like insulin or sulfonylureas (e.g., glipizide or glyburide), can also contribute to weight gain. All three drugs lower blood sugar and promote weight loss, but tirzepatide currently shows the strongest combined A1c reduction...

Today we’re talking about peptides being researched for addiction. We’ll unpack the science behind the incretin system, how those pathways tie into reward and substance use, and focus in on the newest triple‐agonist retatrutide. We’ll also look at early evidence for alcohol, tobacco and other substance-use disorders when using certain peptide therapies. If you want to support what we do, head over to our Partners Page. You'll find some amazing brands we trust—and by checking them out, you're helping us keep the podcast going. https://pepties.com/partners/ What are GLP-1, GIP and the “dual/triple” agonists? First, let’s review some biology to ground the discussion. GLP-1 (glucagon‐like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) are incretin hormones. Incretins are gut hormones that help with digestion and blood sugar control. They’re released by the gut in response to food. GLP-1 raises insulin levels after you eat to help lower blood sugar, slows gastric emptying, and reduces appetite. It also reduces how much glucagon your body makes. This helps to lower your blood sugar. Medications like semaglutide and dulaglutide work by mimicking GLP-1 and are often referred to as “GLP-1 agonists”. GIP has somewhat overlapping but distinct roles from GLP-1. It too, influences insulin secretion, but it also helps with fat metabolism. In a nut shell, GIP helps fat cells respond more efficiently to insulin so they release stored fat to be used as energy when your body needs it. This process helps your metabolism shift from just storing energy to burning fat for fuel. Medications like tirzepatide work by mimicking both GLP-1 and GIP and are often referred to as “dual” agonists. When GIP and GLP-1 are activated together — like in tirzepatide — they work as a team: GLP-1 helps control appetite and slow down digestion. GIP boosts how your body handles insulin and energy. Together, they help reduce hunger, improve metabolism, and burn fat more efficiently. Now here’s where it gets a bit tricky. A newer medication that’s still in development, retatrutide, works on three hormone pathways: GLP-1, GIP, and glucagon receptors. It’s called a “triple agonist”, and even though it activates the glucagon receptor, it doesn’t cause high blood sugar like you might expect. It’s about balance. In type 2 diabetes and obesity, the body’s hormone signals are out of balance. Retatrutide gently activates the glucagon receptor, but at the same time it strongly activates GLP-1 and GIP receptors — which still help control blood sugar and increase insulin. So blood sugar stays stable or even improves overall. Glucagon doesn’t just affect blood sugar — it also increases metabolism and helps the body burn fat and calories. By slightly stimulating glucagon receptors, retatrutide can boost energy use and promote fat loss without causing big spikes in blood sugar. As a result, you get the blood sugar control of GLP-1 and GIP, plus the fat-burning benefits of glucagon activation — leading to even greater weight loss and metabolic improvement. Right now, retatrutide is in phase 3 clinical trials, which are the final stage of testing before approval. These studies are expected to finish in early 2026, and if results look good, the FDA could approve retatrutide as early as 2027. Addiction Why is this relevant for addiction? Because the gut-brain axis, reward circuitry, and the pathways that regulate “wanting/consuming” food overlap with those involved in substance use. Appetite, reward, and craving may share neural substrates (dopamine, GABA, mesolimbic system) and so a drug that reduces drive to eat might also modulate drive to drink, smoke or use other substances. The link between GLP-1/related drugs and substance use disorders Let’s now dive into what the research says about GLP-1 receptor agonists (and related medications) in the context of alcohol, tobacco, and other substances. Let’s start with what we know from animal...

Today, we’ll examine an important debate in nutrition: whether skipping breakfast or skipping dinner is more effective for your health and metabolism. We’ll unpack what the research says, how your body’s internal clock affects metabolism, and why the timing of your last meal can make or break your weight loss—especially if you’re on a GLP-1 medication like semaglutide, dual GIP/GLP-1 like tirzepatide, or triple agonist like retatrutide. If you want to support what we do, head over to our Partners Page. You'll find some amazing brands we trust—and by checking them out, you're helping us keep the podcast going. https://pepties.com/partners/ Let’s get into it. Circadian Rhythms and Eating Windows Our bodies are wired to follow a circadian rhythm—a 24-hour cycle that controls hormones like melatonin, cortisol, and insulin. One key thing to understand is that your body follows the rhythm of the day. When it’s light out, you’re naturally wired for activity—your metabolism is active, digestion works efficiently, and your body is more sensitive to insulin. As daylight fades, melatonin levels rise, signaling it’s time to slow down, rest, and prepare for sleep. Here’s the kicker: melatonin doesn’t just make you sleepy—it also reduces insulin sensitivity. That means when you eat late at night—say at 8 or 9pm—your body doesn’t handle sugar or calories as well. Instead of using that energy, you’re more likely to store it as fat. So, a meal at 5pm when it’s still light out? Your body’s insulin response is stronger. You burn and use more of what you eat. But a meal at 9pm in the dark? Your body’s gearing up for sleep, not digestion. Calories from that meal are more likely to go into fat storage. Breakfast vs. Dinner Skipping—What the Data Says Let’s talk about what the research shows when it comes to skipping breakfast versus skipping dinner. Several studies have looked at early time-restricted feeding, where you eat earlier in the day, like between 8 a.m. and 4 p.m., versus eating later, where you skip breakfast and stretch meals into the evening. One of the most cited studies, published in Cell Metabolism. The study looked at men with prediabetes who followed an early time-restricted feeding schedule for five weeks. Even though they didn’t lose weight, they had significant improvements in insulin sensitivity, blood pressure, and markers of oxidative stress compared to those eating over a twelve-hour window. The takeaway? Eating earlier in the day improved metabolic function even without reducing calories. Another study found that early eaters experienced lower evening hunger and better fat oxidation, meaning their bodies were burning fat more efficiently. By contrast, those eating later in the day had higher insulin and glucose levels after meals, signaling greater insulin resistance. And more broadly, research consistently shows that eating late at night, especially after seven or eight in the evening, is linked to increased body fat and higher risks of obesity and type 2 diabetes. The reason is straightforward: insulin sensitivity drops as the day goes on, so your body is less efficient at processing glucose at night, and those late calories are more likely to be stored as fat, especially around the belly. So while skipping breakfast might be easier for some people, from a metabolic standpoint, skipping dinner—or at least finishing it earlier—tends to be more beneficial. This connects directly to why fasting works for weight loss. Fasting gives your insulin a chance to drop, which signals your body to tap into stored fat for energy. Front-loading your meals earlier in the day aligns with your body’s natural rhythm: insulin sensitivity is higher, digestion is more efficient, and your body has more opportunity to burn fat overnight. People who eat earlier often report feeling more energized, less hungry in the evening, and sleeping better—all key factors in long-term weight control. Now, if you’re taking medications...

Today, we’re talking about tesamorelin, a peptide that works through the growth hormone pathway and is especially effective when it comes to targeting stubborn belly fat. If you want to support what we do, head over to our Partners Page. You'll find some amazing brands we trust—and by checking them out, you're helping us keep the podcast going. https://pepties.com/partners/ So, what exactly is tesamorelin? In simple terms, it’s a synthetic growth hormone-releasing hormone (GHRH) analog—basically, it signals your pituitary gland to release more growth hormone (GH). Why does that matter? Because GH plays a big role in fat metabolism, especially when it comes to visceral fat, the deep fat that surrounds your organs in your abdominal region. Here’s how it works: when GH levels rise, your body starts breaking down fat for energy—a process called lipolysis. Visceral fat, in particular, is very responsive to GH. Reducing this type of fat isn’t just about looking better; it also improves metabolic health, boosts insulin sensitivity, and lowers inflammation, all of which support long-term health and reduce your risk of heart disease. Why not just give GH directly? Your body only produces a certain amount of GH naturally, and this declines with age. Giving exogenous GH can boost levels quickly, but it comes with higher risks like swelling, joint pain, and sometimes insulin resistance if overused. Tesamorelin, on the other hand, stimulates your own pituitary gland to release GH naturally, which tends to be safer and more physiologic over time. That said, GH injections might be preferred in certain clinical scenarios, but for most people, tesamorelin offers a more controlled approach. What about side effects? Some common ones include joint pain, swelling, and muscle aches. These happen because GH causes fluid retention and increased tissue growth, which can put pressure on joints and muscles. Also, tesamorelin can slightly increase blood sugar, so people with diabetes or prediabetes should be monitored carefully. But why does this happen? Since tesamorelin works by boosting your growth hormone, it can have an impact on how your body handles glucose. Growth hormone naturally makes your body a little less sensitive to insulin, which means your cells don’t take up sugar as efficiently. So, some people might notice a slight rise in fasting blood sugar when they start using tesamorelin. But here’s the interesting part: growth hormone also increases IGF-1, which has some insulin-like effects. In most healthy people, this helps balance things out, so blood sugar doesn’t spike dramatically. But if someone already has prediabetes or type 2 diabetes, it’s something to keep an eye on. The takeaway? Tesamorelin can slightly raise blood sugar, but it’s usually manageable. Regular monitoring is smart, especially for anyone with a history of blood sugar issues. And compared to direct growth hormone injections, tesamorelin tends to have less of an effect on blood sugar because it stimulates your body to release GH naturally, instead of flooding your system with it. Typical dosing of tesamorelin For men, peptide therapy is often 1 mg at night to support natural GH peaks during sleep, and 1 mg in the morning before fasted cardio or exercise. Women usually do 1 mg daily. Tesamorelin can be expensive, so many people cycle it 5 days on, 2 days off to reduce cost, or just do 1 mg at night, which still supports GH production and can even improve sleep. Typically, tesamorelin is cycled for 8 weeks on, then 8 weeks off, and most people start noticing results after 4 to 6 weeks. This cycling helps manage cost, reduce potential side effects, and allows the body to maintain responsiveness to the therapy. My Final thoughts Tesamorelin is a powerful tool for targeting visceral fat and improving body composition safely through your natural GH pathways. It’s not a cheap therapy, but if used strategically—especially timed with sleep or exercise—it can...

I’m so glad you’re here today because we’re diving into a therapy that people are buzzing about—GLOW peptide therapy. If you want to support what we do, head over to our Partners Page. You'll find some amazing brands we trust—and by checking them out, you're helping us keep the podcast going. https://pepties.com/partners/ Now, you’ve probably heard me talk about individual peptides before, but this one’s a peptide stack—a combination of three peptides that are designed to work together. And honestly, the name says it all. People who use this blend often say they recover faster, their skin looks healthier, and they just feel better overall. That’s why it’s called GLOW. So today, I’m going to walk you through what GLOW peptide therapy is, what’s actually in it, how each of these peptides work, typical dosing, cycles, side effects, who should avoid it, and finally—I’ll go through some of the most common questions people ask. The Three Peptides in GLOW GLOW therapy combines BPC-157, TB-500 or thymosin beta-4, and GHK-Cu. Each one does something unique, but when you put them together, you get this synergistic effect that’s bigger than the sum of its parts. Let’s start with BPC-157. This peptide is naturally derived from something we all have in our stomach lining—it’s literally called the body protection compound. And the name fits. It helps protect and repair tissue, calm down inflammation, and even support gut health. A lot of people first hear about BPC-157 because athletes use it for muscle strains, tendon injuries, or joint pain. But it’s also been studied for gut issues like ulcers and leaky gut. The magic is in how it helps new blood vessels form so your tissues can actually heal faster and stronger. The next thing I want to touch on is that the GLOW peptide stack sometimes lists TB-500 or Thymosin Beta-4 (TB4) as if they’re interchangeable. And while they’re closely related, they’re not exactly the same. Both of them are best known for their role in healing and recovery. They guide cells to the site of an injury, help reduce scar tissue, improve blood flow by encouraging new blood vessel growth, and calm down excess inflammation so real healing can happen. Where they start to differ is in their scope of action. Thymosin Beta-4 is the full-length, naturally occurring peptide — the master version, if you will. Because it’s the entire chain, it interacts with more pathways and has been studied in a wide range of areas: wound healing, heart repair after a heart attack, corneal healing, brain and nerve protection, even immune system regulation. TB-500, on the other hand, is a synthetic fragment of Thymosin Beta-4. It contains the “active core” that drives cell migration and blood vessel growth. That makes it very effective for tissue repair, tendon healing, wound closure, and circulation. But it doesn’t have all the extra regulatory sections that give the full peptide those broader effects on the heart, brain, or immune system. What’s good to know, is that in practice, most formulations use TB-500 because it’s more stable (both in the body and for storage), widely available, and it’s cost-effective. Some clinics may use the full Thymosin Beta-4, but that’s far less common due to the cost of production. From a user perspective, both serve the same purpose in the stack: recovery, regeneration, and repair. However, TB-500 does not have all the broader effects that the full-length Thymosin Beta-4 peptide has. Think of it this way, TB-500 tends to be seen as more targeted — very good at tissue and tendon repair, wound closure, and improving circulation, but without the same wide-ranging effects on the heart, brain, or immune system that you see with the complete TB4 peptide. Okay, moving along to the last component of the GLOW peptide stack: GHK-Cu or the copper peptide. You might’ve already seen this one in the skincare world—creams and serums often brag about having copper peptides because they boost collagen,...