Plain English with Derek Thompson

Dramatic regime change. Moderate regime evolution. A calamitous regional conflict. Or … no change at all. Today we consider how the Iran conflict might evolve following the killing of Supreme Leader Khamenei with Karim Sadjadpour, an American policy analyst at the Carnegie Endowment for International Peace. Subscribe to our YouTube channel here: https://www.youtube.com/@PlainEnglishwithDerekThompson If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek ThompsonGuest: Karim SadjadpourProducer: Devon Baroldi Learn more about your ad choices. Visit podcastchoices.com/adchoices

The modern world swims in numbers: work metrics, fitness metrics, health metrics, social media metrics. Sometimes the quantification of life can make things better. But very often, I think they force us to play the games we can measure rather than the games we value. The quantified life has become a modern religion: a system of values that takes us over and keeps us from living the life we want. Today’s guest is the philosopher C. Thi Nguyen. He is the author of the book The Score: How to Stop Playing Somebody Else's Game. We talk about metrics, the games of life, and how to listen to the parts of ourselves that cannot be reduced to numbers. Subscribe to our YouTube channel here: https://www.youtube.com/@PlainEnglishwithDerekThompson If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek Thompson Guest: C. Thi Nguyen Producer: Devon Baroldi Learn more about your ad choices. Visit podcastchoices.com/adchoices

The GLP-1 drug revolution has taken the medicine world by storm. I’ve done several episodes on the science of GLP-1s. But we’ve never done an episode like this before, where we talk to one of the most important people in charge of guiding the GLP-1 drug revolution. Our guest is Dave Ricks, the CEO of Eli Lilly, the largest pharmaceutical company in the world. First we talk about what makes the GLP-1 drug category special and the science that Lilly is doing to improve these drugs. Then, we talk about the pharmaceutical industry more broadly. How it works. How it could work better. And I don’t shy away from the question that I think Pharma CEOs need to take much more seriously: If the pharmaceutical industry is theoretically more devoted than any other economic category to saving people’s lives, why do Americans distrust it more than any other industry in the entire economy? Subscribe to our YouTube channel here: https://www.youtube.com/@PlainEnglishwithDerekThompson If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek ThompsonGuest: David RicksProducer: Devon Baroldi Learn more about your ad choices. Visit podcastchoices.com/adchoices

Donald Trump suffered a huge blow Friday when the Supreme Court struck down the centerpiece of his economic policy: his vast system of tariffs. So, what happens now? Harvard’s Jason Furman explains the implications for the U.S. economy, consumers, global trade, and Trump’s strategy of centralizing power in the executive branch and using trade policy as a means of wringing concessions out of other counties. Subscribe to our YouTube channel here: https://www.youtube.com/@PlainEnglishwithDerekThompson If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek ThompsonGuest: Jason FurmanProducer: Devon Baroldi Learn more about your ad choices. Visit podcastchoices.com/adchoices

In the mid-20th century, a group of media and communications scholars proposed that the shift from spoken to written language—from orality to literacy—transformed our politics, our media, our social relations, and even our sense of consciousness. Today we’re undergoing another shift: from a literate culture to something stranger—a post-literate world awash in social media and digital communications in which oral traditions are making a comeback. Bloomberg’s Joe Weisenthal, the cohost of the Odd Lots podcast, has called this one of the most important trends in the world. Today he explains how he got hooked on orality theory and why it’s the skeleton key that unlocks so many oddities of the modern world. Subscribe to our YouTube channel here: https://www.youtube.com/@PlainEnglishwithDerekThompson If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek Thompson Guest: Joe Weisenthal Producer: Devon Baroldi Learn more about your ad choices. Visit podcastchoices.com/adchoices

In his epic cover story for The Atlantic this month, staff writer Josh Tyrangiel spoke to dozens of economists, workers, tech CEOs, and AI experts about the danger that artificial intelligence might pose to the labor force. Is AI developing the capacity to automate and even replace millions of white-collar jobs, as many technologists and some economists predict? Or is this a normal technology that, like previous generations of technology, will have a much slower effect on the workforce? We cover several scenarios before asking: Why does it seem like nobody in politics is paying close enough attention to this story? Links: https://www.theatlantic.com/magazine/2026/03/ai-economy-labor-market-transformation/685731/ Subscribe to our YouTube channel here: https://www.youtube.com/@PlainEnglishwithDerekThompson If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek Thompson Guest: Josh Tyrangiel Producer: Devon Baroldi Learn more about your ad choices. Visit podcastchoices.com/adchoices

Hello! I’m back from paternity leave just in time to talk about the biggest media earthquake of the year (so far): the Washington Post meltdown. For decades, the Post was a journalistic gem with superior coverage of politics. Last week, billionaire owner Jeff Bezos decided to gut roughly a third of the staff after the paper lost hundreds of millions of dollars in the last few years. Today’s guest is Jim VandeHei, the cofounder of Politico and Axios and a former Post reporter. We talk about the decades-long rise and fall of the Post before zooming out to talk about the most important changes in news media over the past 20 years, the secret of 21st-century media success, and the coming storm of AI. To read more about Derek’s opening comments on how the future of the news industry is going back to past, check out his Atlantic article on the subject here: https://www.theatlantic.com/ideas/archive/2018/12/post-advertising-future-media/578917/ Subscribe to our YouTube channel here: https://www.youtube.com/@PlainEnglishwithDerekThompson If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek Thompson Guest: Jim VandeHei Producer: Devon Baroldi Learn more about your ad choices. Visit podcastchoices.com/adchoices

Throughout December and January, we’ve been re-airing some of our favorite episodes of the past year and beyond, and today's episode marks the end of our "best of" series for this year! This list includes interviews that really stuck with me and some others that you guys had tons of feedback and thoughts on … including this one!“What’s the Matter With America’s Food?” originally aired September 26, 2025.If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com.Host: Derek ThompsonGuests: Julia Belluz and Kevin HallProducer: Devon Baroldi Learn more about your ad choices. Visit podcastchoices.com/adchoices

Throughout December and January, we’re going to be re-airing some of our favorite episodes of the past year and beyond. This list includes interviews that really stuck with me and some others that you guys had tons of feedback and thoughts on … including this one! “This Is How the AI Bubble Could Burst” originally aired September 23, 2025. If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek ThompsonGuest: Paul KedroskyProducer: Devon Baroldi Learn more about your ad choices. Visit podcastchoices.com/adchoices

Throughout December and January, we’re going to be re-airing some of our favorite episodes of the past year and beyond. This list includes interviews that really stuck with me and some others that you guys had tons of feedback and thoughts on … including this one! “The Healthiest "Super-Agers" Have One Thing in Common, According to a 25-Year Study” originally aired August 27th, 2025. If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek ThompsonGuest: Dr. Sandra WeintraubProducer: Devon Baroldi Learn more about your ad choices. Visit podcastchoices.com/adchoices

Throughout December and January, we’re going to be re-airing some of our favorite episodes of the past year and beyond. This list includes interviews that really stuck with me and some others that you guys had tons of feedback and thoughts on … including this one! “The Modern World Is Changing America’s Personality for the Worse” originally aired August 13, 2025. If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek ThompsonGuest: John Burn-MurdochProducer: Devon Baroldi Learn more about your ad choices. Visit podcastchoices.com/adchoices

Throughout December and January, we’re going to be re-airing some of our favorite episodes of the past year and beyond. This list includes interviews that really stuck with me and some others that you guys had tons of feedback and thoughts on … including this one! “What Experts Really Think About Smartphones and Mental Health” originally aired June 4th, 2025. If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek ThompsonGuest: Jay Van BavelProducer: Devon Baroldi Learn more about your ad choices. Visit podcastchoices.com/adchoices

Throughout December and January, we’re going to be re-airing some of our favorite episodes of the past year and beyond. This list includes interviews that really stuck with me and some others that you guys had tons of feedback and thoughts on … including this one! “How Gen Z Sees the World” originally aired March 12, 2025. If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek ThompsonGuest: Kyla ScanlonProducer: Devon Baroldi Learn more about your ad choices. Visit podcastchoices.com/adchoices

Throughout December and January, we’re going to be re-airing some of our favorite episodes of the past year and beyond. This list includes interviews that really stuck with me and some others that you guys had tons of feedback and thoughts on … including this one! “A Grand, Unified Theory of Why Americans Are So Unhealthy” originally aired June 18, 2025. If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek Thompson Guests: David Kessler and Eric Topol Producer: Devon Baroldi Learn more about your ad choices. Visit podcastchoices.com/adchoices

Throughout December and January, we’re going to be re-airing some of our favorite episodes of the past year and beyond. This list includes interviews that really stuck with me and some others that you guys had tons of feedback and thoughts on … including this one! “The Antisocial Century” originally aired January 10, 2025. If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek Thompson Guest: Nick Epley Producer: Devon Baroldi Learn more about your ad choices. Visit podcastchoices.com/adchoices

Throughout December and January, we’re going to be re-airing some of our favorite episodes of the past year and beyond. This list includes interviews that really stuck with me and some others that you guys had tons of feedback and thoughts on … including this one! “How to Be Happy and the Science of Cognitive Time Travel” originally aired August 9, 2024. If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek Thompson Guest: Laurie Santos Producer: Devon Baroldi Learn more about your ad choices. Visit podcastchoices.com/adchoices

One of my favorite theories about the modern world is the idea that culture is "stuck." Whether the decline of ornamentation in modern architecture, or the fact that every corporate logo looks the same now, or the fact that Gen Z's favorite television was all made in the 1990s and 2000s, or the sequel fetish in Hollywood, or the theory that old music is eating new music on Spotify, the evidence of cultural stagnation abounds. But is there one grand theory that explains all of it? The psychologist and writer Adam Mastroianni thinks so. He joins Derek to discuss. If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek Thompson Guest: Adam Mastroianni Producers: Devon Baroldi Links:https://www.slowboring.com/p/the-hidden-cause-of-cultural-stagnationhttps://www.experimental-history.com/p/the-decline-of-deviancehttps://www.astralcodexten.com/p/whither-tartariahttps://www.theatlantic.com/ideas/archive/2021/12/america-innovation-film-science-business/620858/https://www.theatlantic.com/ideas/archive/2021/12/america-really-running-out-original-ideas/621055/https://www.theatlantic.com/culture/2025/11/blank-space-book-excerpt-culture/685037/ Learn more about your ad choices. Visit podcastchoices.com/adchoices

The University of California San Diego is one of the best public colleges in America. So it was fairly shocking when the school released a report on the steep decline in academic preparedness of its freshman. The number of incoming students in need of remedial math has surged in the past few years. These students did not fail high school math. Many of them got straight A's. Other colleges have seen similar trends: declining mathematical ability from students who aced their high school tests. I think that there are several ways to frame the problem we’re looking at here. One is that American kids can’t do math: That’s the headline of a recent Atlantic article by Rose Horowitch. Another frame, as Kelsey Piper writes in the online magazine The Argument, is that grades have stopped meaning anything. I think that the full story is somewhere in between. The age of grade inflation is also the age of achievement deflation. We are giving more and more A's to students who are learning less and less. There is a lot of talk these days about America moving into a postliterate future. One piece of evidence for this is declining test scores for literacy among students and adults. Fewer people talk about a post-numerate future. The problem here is bigger than UC San Diego. National assessments in the U.S. and even throughout the developed world show that people are getting worse at math. But why? Today we have three guests to help us answer these questions. Rose Horowitch of The Atlantic, Kelsey Piper of The Argument, and Joshua Goodman, an associate professor of education and economics at Boston University. We talk about plummeting math scores for American students, why it’s happening, and why it matters at a moment when carbon-based humans seem to be getting dumber at the very moment that silicon-based machines are getting smarter. If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek Thompson Guests: Rose Horowitch, Kelsey Piper and Joshua Goodman Producers: Devon Baroldi Learn more about your ad choices. Visit podcastchoices.com/adchoices

Many AI experts believe that some time in the next few years, we will build something close to artificial general intelligence (AGI), a system that can do nearly all valuable cognitive work as well as or better than humans. What happens to jobs, wages, prices, and politics in that world? To explore that question, Derek is joined by Anton Korinek, an economist at the University of Virginia and one of the leading thinkers on the economics of transformative AI. Before he focused on superintelligence, Anton studied financial crises and speculative booms, so he brings a rare mix of macroeconomic skepticism and technological optimism. They talk about quiet AGI versus loud AGI, Baumol’s cost disease, robots, mass unemployment, and what kinds of policies might prevent an “AGI Great Depression” and keep no American left behind. If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek Thompson Guest: Anton Korinek Producers: Devon Baroldi Learn more about your ad choices. Visit podcastchoices.com/adchoices

Sometimes, the perfect guest to discuss your own writing is ... you. On this special crossover episode, I am interviewed by Ben Smith and Max Tani of Semafor's Mixed Signals podcast about my recent essay, "Everything Is Television." During our conversation, which you can also find on the Mixed Signals feed, we discuss TV, politics, the definition of charisma, and much more. If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Hosts: Ben Smith and Max Tani Guest: Derek Thompson Listen to my episode on the Mixed Signals feed HERE. You can find my essay "Everything is Television" HERE. Learn more about your ad choices. Visit podcastchoices.com/adchoices