EBRC In Translation

In this episode, we interview Dr. Prachee Avasthi, Co-founder and CSO of Arcadia Science and previous Associate Professor of Biochemistry and Cell Biology at Dartmouth. We talk with Prachee about her many layers of experiments, from mining new biological tools to building new organizational structures for open science. We also talk with her about non-canonical career paths, science publishing models, and much more! For more information about EBRC, visit our website at ebrc.org. If you are interested in getting involved with the EBRC Student and Postdoc Association, fill out a membership application for graduate students and postdocs or for undergraduates and join today! Episode transcripts are the unedited output from Whisper and likely contain errors.

In this episode, we interview Drew Endy, a professor in the Department of Biological Engineering at Stanford University. We talk to Drew about making the engineering of living systems routine, how biology is the perfect technology to interface with joules, bits, and atoms, the concept of synbiophobia-phobia, teaching biological literacy via the “Labrary”, the new discipline of Awestronomy, and so much more. In this episode, Drew mentions several interesting reads: The Genesis of a Curriculum on Biological Engineering The Morals of Measurement Homo Ludens For more information about EBRC, visit our website at ebrc.org. If you are interested in getting involved with the EBRC Student and Postdoc Association, fill out a membership application for graduate students and postdocs or for undergraduates and join today! Episode transcripts are the unedited output from Whisper and likely contain errors.

In this episode, we interview Geoffrey Otim, founder and CEO of SynBio Africa and founder of iGEM Makarere, the first iGEM team in East Africa. We discuss the unique health, agricultural, climate, biosecurity, and energy challenges being tackled by the emerging engineering biology community in Africa. We also talk about his policy advocacy, African Union-led initiatives, and the cultural, political, and funding headwinds faced by African scientists. For more information about EBRC, visit our website at ebrc.org. If you are interested in getting involved with the EBRC Student and Postdoc Association, fill out a membership application for graduate students and postdocs or for undergraduates and join today! Episode transcripts are the unedited output from Whisper and likely contain errors.

In this episode, we interview Dr. John Inglis and Dr. Richard Sever, the executive director and assistant director respectively of the Cold Spring Harbor Laboratory Press. John and Richard also co-founded both bioRxiv and medRxiv, the primary preprint servers for biological and medical research. We discuss what makes the Cold Spring Harbor Laboratory Press unique, how they founded bioRxiv and medRxiv, how preprinting allows us to do experiments on the publication system itself, and much more! In the episode, John recommends a book on career options for biomedical scientists. Note from the editor: Unfortunately, there were some minor issues with Richard's source audio which resulted in some occasional skipping. Our apologies for this! For more information about EBRC, visit our website at ebrc.org. If you are interested in getting involved with the EBRC Student and Postdoc Association, fill out a membership application for graduate students and postdocs or for undergraduates and join today! Episode transcripts are the unedited output from Whisper and likely contain errors.

In this episode, we speak with Dr. Sean Simpson, strategic advisor and former CSO of LanzaTech. We talk with Sean about using biology to convert greenhouse gases into ethanol, how to scale up and sell a novel biological process, and the economic and policy requirements of engineering biology for global challenges. For more information about EBRC, visit our website at ebrc.org. If you are interested in getting involved with the EBRC Student and Postdoc Association, fill out a membership application for graduate students and postdocs or for undergraduates and join today! Episode transcripts are the unedited output from Whisper and likely contain errors.

In this episode, we interview Dr. Tony Kulesa, a Principal at the VC firm Pillar. We talk to Tony about his work to open source the biotech company creation process, overrated and underrated investment theses, reading and writing to all the different scales of biology and more! To learn more about founder-led biotech, check out some of Tony's writing on the topic here. For more information about EBRC, visit our website at ebrc.org. If you are interested in getting involved with the EBRC Student and Postdoc Association, fill out a membership application for graduate students and postdocs or for undergraduates and join today! Episode transcripts are the unedited output from Whisper and likely contain errors.

In this episode, we speak with Melissa Takahashi, an Assistant Professor at California State University Northridge in the Department of Biology. We talk with Melissa about her research on the biological principles behind RNA gene regulation in bacteria, being a professor at a primarily undergraduate institution, helping students realize they can be scientists, and more! For more information about EBRC, visit our website at ebrc.org. If you are interested in getting involved with the EBRC Student and Postdoc Association, fill out a membership application for graduate students and postdocs or for undergraduates and join today! Episode transcripts are the unedited output from Whisper and likely contain errors.

In this episode, we are joined by Dr. Mustafa Khammash, Professor of Control Theory and Systems Biology in the Department of Biosystems Science and Engineering at ETH-Zurich. We talk with Mustafa about integrating control theory into synthetic biology, designing computer/biology interfaces, starting a wet lab as a tenured computational professor, the need for new theoretical frameworks for biological design, and more! Notes: During the episode, Dr. Khammash references two different papers from his lab, linked below. Cybergenetics: Theory and Applications of Genetic Control Systems Universal structural requirements for maximal robust perfect adaptation in biomolecular networks For more information about EBRC, visit our website at ebrc.org. If you are interested in getting involved with the EBRC Student and Postdoc Association, fill out a membership application for graduate students and postdocs or for undergraduates and join today! Episode transcripts are the unedited output from Whisper and likely contain errors.

In this episode we’re joined by Eldora Ellison, PhD, director at law firm Sterne Kessler and lead patent strategist for the CVC group in the MIT-Berkeley CRISPR patent litigation. We discuss the long and winding road of filing and defending patents, what it’s like to go from PhD scientist to law firm partner, how biotechnology advances are challenging the world of patents, and more! Links related to the episode: Careers at Sterne Kessler U.S. Biotechnology Patent Law by Jorge Goldstein For more information about EBRC, visit our website at ebrc.org. If you are interested in getting involved with the EBRC Student and Postdoc Association, fill out a membership application for graduate students and postdocs or for undergraduates and join today! Episode transcripts are the unedited output from Whisper and likely contain errors.

In this episode, we interview Vineeta Agarwala, MD, PhD, a general partner at Andreesen Horowitz (a16z) where she leads investments in the group’s bio + health fund. We talk to Vineeta about investing in synthetic biology startup companies, a day in the life of a VC, following the good people, and more! Disclosures: The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. In addition, this content may include third-party advertisements; a16z has not reviewed such advertisements and does not endorse any advertising content contained therein. This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments for which the issuer has not provided permission for a16z to disclose publicly as well as unannounced investments in publicly traded digital assets) is available at https://a16z.com/investments/. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information. For more information about EBRC, visit our website at ebrc.org. If you are interested in getting involved with the EBRC Student and Postdoc Association, fill out a membership application for graduate students and postdocs or for undergraduates and join today! Episode transcripts are the unedited output from Whisper and likely contain errors.

In this episode, we interview Dr. Henry Lee, CEO of Cultivarium, a focused research organization that aims to expand access to novel microorganisms. We discuss the world’s fastest-growing bacterium, the challenges of domesticating non-model microbes, new organizational models for science, robotic dogs, and more! If you are interested in Cultivarium, you can learn more and get involved at https://www.cultivarium.org/. For more information about EBRC, visit our website at ebrc.org. If you are interested in getting involved with the EBRC Student and Postdoc Association, fill out a membership application for graduate students and postdocs or for undergraduates and join today! Episode transcripts are the unedited output from Whisper and likely contain errors.

In this episode, we interview Dr. Doug Friedman, CEO of the BioIndustrial Manufacturing and Design Ecosystem (BioMADE) and President of the Engineering Biology Research Consortium (EBRC). We talk about how to build and grow community-driven organizations, what it takes to be an expert in DC, visions for the future of the bioeconomy, and more! For more information about EBRC, visit our website at ebrc.org. If you are interested in getting involved with the EBRC Student and Postdoc Association, fill out a membership application for graduate students and postdocs or for undergraduates and join today! Episode transcripts are the unedited output from Whisper and likely contain errors.

In this episode, we interview Dr. Hana El-Samad, a Professor at UCSF, editor-in-chief of GEN biotechnology, and a founding PI at Altos labs, whose research focuses on controlling mammalian cell behavior with genetic circuits. We talk with Dr. El-Samad about her work on controlling mammalian cell behavior, her role at and transition to Altos labs, committing to equity in STEM, the mission of GEN biotechnology, and more! Notes and links: Fund Black Scientists Director Lander, the time is now For more information about EBRC, visit our website at ebrc.org. If you are interested in getting involved with the EBRC Student and Postdoc Association, fill out a membership application for graduate students and postdocs or for undergraduates and join today! Episode transcripts are the unedited output from Whisper and likely contain errors.

In this episode, we interview Dr. Ross Cloney, a Senior Editor at Nature Communications, focusing on the areas of synthetic biology, genome engineering, and therapeutic biotechnology. We talk with Ross about: how a manuscript becomes a publication; what it’s like to be an editor; how to make scientific publishing more diverse, equitable, and inclusive; what the future of scientific journals looks like; and more! For more information about EBRC, visit our website at ebrc.org. If you are interested in getting involved with the EBRC Student and Postdoc Association, fill out a membership application for graduate students and postdocs or for undergraduates and join today! Episode transcripts are the unedited output from Whisper and likely contain errors.

In this episode, we interview Dr. Doug Densmore, a professor at Boston University and co-founder of Lattice Automation, Asimov. and Biosens8. We talk to Doug about developing laboratory workflows as a service for engineering biology, finding your own management style, and treating automation and algorithms as first-class scientific citizens. Links and notes for the episode: Lynn Doucette-Stamm Runs the BU COVID testing facility Programming Biology Stem Pathways Asimov Lattice biosens8 International Workshop on Bio-Design Automation EBRC SPA Mentorship Program For more information about EBRC, visit our website at ebrc.org. If you are interested in getting involved with the EBRC Student and Postdoc Association, fill out a membership application for graduate students and postdocs or for undergraduates and join today! Episode transcripts are the unedited output from Whisper and likely contain errors.

In this episode, we interview Dr. Tobias Erb, a member of the Max Planck Society and Director of the Max Planck Institute for terrestrial Microbiology in Marburg, Germany. We talk to Tobias about building synthetic carbon dioxide fixation pathways, similarities and differences between science in the US and Europe, and the superiority of German bread and beer. For more information about EBRC, visit our website at ebrc.org. If you are interested in getting involved with the EBRC Student and Postdoc Association, fill out a membership application for graduate students and postdocs or for undergraduates and join today! Episode transcripts are the unedited output from Whisper and likely contain errors.

In this episode, we interview Dr. David Baker, a professor at the University of Washington and the director of the Institute for Protein Design. We talk to David about the practical and philosophical sides of protein design, the impact of machine learning on protein structure prediction and design, and how video games can be used for science. For more information about EBRC, visit our website at ebrc.org. If you are interested in getting involved with the EBRC Student and Postdoc Association, fill out a membership application for graduate students and postdocs or for undergraduates and join today! Episode transcripts are the unedited output from Whisper and likely contain errors.

In this episode, we interview Dr. Emily Leproust, CEO and co-founder of Twist Bioscience, a leading and rapidly growing synthetic biology and genomics company that is well-known for its disruptive DNA synthesis platform. We talk to Dr. Leproust about the future of DNA synthesis, making cloning obsolete, and eating challenges for breakfast. This episode was recorded in September 2021. During the interview, Emily mentions the publication of an article "last week" that happened in September of 2021. You can find this article here. For more information about EBRC, visit our website at ebrc.org. If you are interested in getting involved with the EBRC Student and Postdoc Association, fill out a membership application for graduate students and postdocs or for undergraduates and join today! Episode transcripts are the unedited output from Whisper and likely contain errors.

In this episode, we interview Dr. Kate Adamala, an assistant professor at the University of Minnesota and a leader in Build-a-Cell, an international community of scientists and policymakers working on building synthetic cells. We talk to Dr. Adamala about building cells from the ground up, life beyond planet Earth, and the definition of life. For more information about EBRC, visit our website at ebrc.org. If you are interested in getting involved with the EBRC Student and Postdoc Association, fill out a membership application for graduate students and postdocs or for undergraduates and join today! Episode transcripts are the unedited output from Whisper and likely contain errors.

In this episode, we interview Dr. Jake Becraft, co-founder of Strand Therapeutics. We talk to Dr. Becraft about running an RNA therapeutics company during the pandemic, the future of synthetic biology and RNA, and advice on converting your graduate school research into a start-up. For more information about EBRC, visit our website at ebrc.org. If you are interested in getting involved with the EBRC Student and Postdoc Association, fill out a membership application for graduate students and postdocs or for undergraduates and join today! Episode transcripts are the unedited output from Whisper and likely contain errors.