JAMAevidence Users' Guides to the Medical Literature

Gordon H. Guyatt, MD, MSc, discusses Assessing the Strength of Recommendations: The GRADE Approach with Per Olav Vandvik, MD, PhD. Related Content: How to Interpret and Use a Clinical Practice Guideline or Recommendation

Host Gordon Guyatt, MD, MSc, discusses Understanding and Applying the Results of a Systematic Review with M. Hassan Murad, MD, MPH. Related Content: How to Read a Systematic Review and Meta-analysis and Apply the Results to Patient CareAcute Treatments for Episodic Migraine in Adults

Gordon H. Guyatt, MD, MSc, discusses Fixed-Effects and Random-Effects Models with M. Hassan Murad, MD. Related Content: Random-Effects Meta-analysis

Gordon H. Guyatt, MD, MSc, discusses Adjusted Analyses in Studies Addressing Therapy and Harm with Thomas Agoritsas, MD, PhD. Related Content: Adjusted Analyses in Studies Addressing Therapy and Harm

Gordon Guyatt, MD, MSc, discusses Spectrum Bias with Reem A. Mustafa. MD, MPH, PhD.

Gordon Guyatt, MD, MSc, discusses Discrimination and Calibration of Clinical Prediction Models with Ana Carolina Alba, MD, PhD. Related Content: Discrimination and Calibration of Clinical Prediction Models With Dr Alba Read Transcript

Host Robert M. Golub, MD, discusses How to Interpret and Use a Clinical Practice Guideline or Recommendation with Gordon H. Guyatt, MD, MSc, and Romina Brignardello-Petersen, DDS, MSc, PhD.

Gordon Guyatt, MD, discusses Measuring Agreement Beyond Chance with Thomas McGinn, MD, MPH. Related Content: Does This Patient Have Infectious Mononucleosis? The Rational Clinical Examination Systematic Review

Gordon H. Guyatt, MD, MSc, discusses Correlation and Regression with Roman Jaeschke, MD, MSc.

Gordon Guyatt, MD, discusses economic analysis with Paul Moayyedi, PhD

Gordon Guyatt, MD, discusses Misleading Presentations of Clinical Trial Results with Victor Montori, MD Related Content: Misleading Presentations of Clinical Trial Results with Dr Victor MontoriWhen Can Intermediate Outcomes Be Used in Clinical Trials?When Guidelines Recommend Shared Decision-making

Anne M. Holbrook, MD and Gordon Guyatt, MD, discuss Surrogate Outcomes from the JAMA Users’ Guides to the Medical Literature Related Content: When Can Intermediate Outcomes Be Used as Surrogate Outcomes? FDA Acceptance of Surrogate End Points for Cancer Drug Approval: 1992-2019 What Constitutes a Valid Surrogate End Point in Cancer Clinical Trials?

Interview with Yun Liu, author of How to Read Articles That Use Machine Learning: Users’ Guides to the Medical Literature

JAMA Deputy Editor Edward Livingston, MD, discusses "Cluster Randomized Trials: Evaluating Treatments Applied to Groups" With William J. Meurer, MD, MS

Ed Livingston, MD, FACS, AGAF, discusses Dose-Finding Trials: Optimizing Phase 2 Data in the Drug Development Process with Kert Viele, PhD

Ed Livingston, MD, FACS, AGAF, discusses Noninferiority Trials: Is a New Treatment Almost as Effective as Another? with Amy Kaji, MD, PhD

Gordon Guyatt, MD, MSc, discusses Decision-making and the Patient with Victor Montori, MD, MSc.

Clinical researchers and biostatisticians use highly specialized language to help them discuss statistics and research methods efficiently. In 2019 JAMA published the JAMA Guide to Statistics and Methods, a book of short reviews that translate that specialized language and explain statistics and methods to a broad physician readership. The book's editors and authors, Edward Livingston, MD, and Roger J. Lewis, MD, PhD, discuss their approach to choosing statistical topics and their objectives in compiling the reviews into book format. Purchase the JAMA Guide to Statistics and Methods at: McGraw-Hill: ja.ma/StatsGuideMH Barnes and Noble: ja.ma/StatsGuideBN Amazon: ja.ma/StatsGuideAmazon

Gordon Guyatt, MD, MSc, discusses the application of the results of systematic reviews and meta-analyses to individual patients with author Thomas Agoritsas, MD.

Dr Edward Livingston discusses How to Use a Subgroup Analysis with Dr Gordon Guyatt