Siim Land Podcast

Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/ Timestamps: 00:00 Intro01:15 TB4 05:02 Thymosin alpha 1 09:44 Join our longevity community 10:43 Epitalon 15:26 MOTS-c 19:30 Humanin 21:32 Cerebrolysin 23:49 Semax 24:40 CJC1295 (Ipamorelin) 26:31 MK677 (Ibutamoren) 28:26 Tesamorelin 29:12 IGF-1 LR3 29:45 Copper GHK 32:22 Retatrutide 33:55 Melanotan 2 35:30 Final overview and rankingMy 2026 longevity routine: https://youtu.be/OceysodInIo100 supplements ranked: https://youtu.be/W8DZbYyuDmA?si=-QhWReblSJGdNoyiStart rewinding your biological clock: https://www.siimland.co/course

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland Timestamps: 00:00 Top Health Factors and Biomarkers That Matter the Most 17:44 Bon Charge sponsorship 18:50 Glycine and cancer risk 22:05 Can supplements improve IQ and cognition 25:19 Best autophagy routines 31:24 Thoughts on young plasma exchange 35:26 Injectible NAD and glutathione 38:05 Too high cortisol from time restricted eating 42:35 Benefits of mini trampolines My 2026 longevity routine: https://youtu.be/OceysodInIo 100 Health Biomarkers Ranked: https://youtu.be/SgKp5mm0ALI?si=M7YkYo6Lelci7kOQ

Dr. Elie Abirached is a Harvard alumnus, and founder of Restore. He is the creator of the Limitless Human methodology, a science driven framework designed to reduce biological age, enhance resilience, and optimise long term health. Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland Timestamps: 00:00 Intro 00:16 How Elie got into fitness and wellness 07:00 Why recovery is not enough 11:14 How Elie got a VO2 max of 70 in his 50s 16:20 Bon Charge sponsorship 17:15 Why VO2 max is such a good biomarker of overall health 19:25 Elie's scientific approach to increase VO2 max 22:30 Low intensity vs high intensity training 27:16 How to know your true maximum heart rate 34:25 How often should you test VO2 max 36:20 Elie's go-to workouts 44:18 Elie's go-to recovery strategies 48:44 Elie's nutrition 55:10 Elie's supplementation 01:00:24 How to start: beginners and advanced individuals Dr Elie Abirached's YouTube channel: https://www.youtube.com/@DrElie-biohacking Dr Elie Abirached's Instagram: https://www.instagram.com/elie.truth

Dr. Daniel Promislow, DPhil, is a Senior Scientist and Scientific Advisor at the HNRCA. He has worked for over 30 years on the biology of aging and has published over 180 papers. Currently, he's working on the Dog Aging Project Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland Timestamps:00:0000:26 What is the Dog Aging Project02:26 Size and longevity in dogs06:06 Why dog ownership is associated with longevity11:06 Bon Charge sponsorship12:00 What lifestyle makes dogs live longer17:10 Diet for dog longevity19:25 Intermittent fasting for dogs24:20 Calorie restriction for dogs28:35 Exercise for dogs31:55 Rapamycin for dogs45:40 Other longevity compounds for dogs57:35 Supplements for dogs My 2026 longevity routine: https://youtu.be/OceysodInIo 100 supplements ranked: https://youtu.be/W8DZbYyuDmA?si=-QhWReblSJGdNoyi

Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/ Timestamps:00:00 Intro00:00 Panel members introduction05:20 Recap of our week at AIWO18:30 Blood marker testing20:40 Longevity World Cup competition30:00 DEXA scan36:35 Physiotherapy and posture analysis37:55 Skin anti-aging treatments41:55 Exosomes and stem cells for skin anti-aging49:20 Unique tests we did at AIWO52:45 Social experience at the retreat Inka Land YouTube: https://www.youtube.com/@iaminkaland Dr Joy Kong YouTube: https://www.youtube.com/@JoyKongMD Dave Pascoe YouTube: https://www.youtube.com/c/davepascoesurl Adam Ficsor YouTube: https://www.youtube.com/@nopara73 Check out our next retreat: https://www.siimland.co/retreat My 2026 longevity routine: https://youtu.be/OceysodInIo 100 supplements ranked: https://youtu.be/W8DZbYyuDmA?si=-QhWReblSJGdNoyiStart rewinding your biological clock: https://www.siimland.co/courseP.S. This is not professional medical advice and should not be taken as such. The creator of this video is not held accountable for your health. Consult your doctor first.

Timestamps: 00:00 Why does longevity matter 03:25 Tracking for preventing chronic diseases 06:14 Advanced longevity therapies we’re excited about 10:30 How long would you like to live 14:25 Will longevity technology become available to everyone 17:27 Big moonshots in longevity 23:32 What does the life of a 70 year old look like in 2040 26:32 Most important step towards your longevity you should take today 28:10 Most overhyped and underrated longevity product 30:25 Emotional health 33:40 Research on mushrooms Panel discussion at Copenhagen Health Week 2025: https://www.youtube.com/@CPHHW/videosWith Julian Assa and Jürgen MehrtensStart rewinding your biological clock: https://www.siimland.co/course

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland Timestamps:00:00 Intro00:44 My results in 202506:19 Body composition goals16:00 Bon Charge sponsorship16:52 My 2025 fitness results25:05 My 2026 fitness goals30:25 My workout plan for 202635:05 My nutrition plan for 202643:27 My supplement protocol for 202646:37 My sleep routine and goals48:47 My bloodwork results for 2025 and goals for 202601:01:07 Auxiliary routines01:05:05 ConclusionGet to top 1% health: https://youtu.be/8M9uHhFf26c Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/Start rewinding your biological clock: https://www.siimland.co/course

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland Timestamps: 00:00 Intro 00:15 100 supplements ranked from worst to best 57:00 Bon Charge sponsorship 57:55 How to eliminate microplastics and heavy metals from your body feat Dr Anil Bajnath 01:27:20 Nutrition masterclass with Physionic and Dr Greg Potter 02:27:25 Exercise masterclass with Physionic and Dr Greg Potter 03:17:15 Best performing video of the year 03:29:30 Top underrated video of the year 03:36:14 Sleep and circadian clock dysfunction feat Dr Greg Potter 04:04:38 Skin anti-aging masterclass with Dr Alexis Ortega Get to top 1% health: https://youtu.be/8M9uHhFf26c

Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/ Timestamps: 00:00 Intro 00:15 Zone 2 cardio 01:44 Napping 03:03 Walking 05:09 Polyphasic sleeping 06:47 Mouth breathing 07:52 Soleus pushups 09:40 Stretching 11:10 Mobility 12:03 Yoga 13:20 HIIT 14:20 Sprinting 14:48 Plyometrics 16:12 Morning sunlight 17:05 Evening sunset 17:52 Blocking out blue light 19:12 Red light therapy 20:37 Infrared light 21:43 Supplements 23:30 Education 25:20 Problem solving 26:14 Weight lifting 26:56 Bilingualism 27:10 Sunbathing 28:54 Tanning beds 30:06 Coffee and teas 31:28 Low carb diet 33:26 Low fat high carb diet 34:04 Vegan diet 34:36 Vegetarian diet 35:00 Carnivore diet 37:07 Paleo diet 37:45 Calisthenics 39:15 Mediterranean diet 40:20 Sugar diet 40:58 Hydration 41:42 Smoking 42:00 Alcohol 43:40 Vaping 44:00 Mouth tobacco 44:35 Hyperbaric oxygen therapy (HBOT) 45:40 Sauna 47:09 Total plasma exchange 47:53 Meditation 48:49 Religion 50:10 Purpose 51:30 Mindfulness 52:14 Intermittent fasting 53:15 Low calorie diet 55:40 If it fits your macros diet 57:30 Pet ownership 58:57 Marriage 01:00:57 Ice bath 01:01:57 Having children 01:03:29 Social health 01:04:23 Having fun and play 01:04:40 Mental health 01:05:03 Extended fasting 01:07:07 Forest bathing 01:08:02 Fasting mimicking diet 01:09:10 Juice fasting 01:09:41 Dry fasting 01:11:16 Protein restriction 01:12:17 Hot baths 01:13:40 Time-restricted eating 01:14:10 Circadian mismatch 01:14:50 Sleep consistency 01:15:23 Chronic stress 01:16:00 Junk food 01:16:25 Water filtration 01:16:50 Air filtration 01:17:00 Outdoor pollution 01:17:20 Sitting lifestyle 01:17:43 Sleep 7-8 hours 01:18:09 Regular bloodtests 01:18:40 Continuous glucose monitoring 01:19:19 Exercise snacks 01:19:57 Standing workdesk 01:20:53 Nasal breathing 01:21:03 Breathing exercises 01:21:38 Recreational drugs and weed 01:22:26 Peptides 01:23:30 HRT & TRT 01:27:04 Sleep 4-6 hours 01:27:28 Stem cell therapy 01:28:17 Team sports 01:28:40 Steroid cycle 01:29:10 Grounding 01:29:32 Mouth taping 01:29:51 Artificial sweeteners 01:31:30 Hypochondria 01:33:50 Overview My 2025 supplement list guide: https://www.siimland.co/supplement-list-2025 100 supplements ranked: https://youtu.be/W8DZbYyuDmA?si=-QhWReblSJGdNoyi Get to top 1% health: https://youtu.be/8M9uHhFf26c Start rewinding your biological clock: https://www.siimland.co/course

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland Timestamps:00:00 What level of sports performance is unhealthy04:15 How much protein is bad for aging and longevity11:45 Bon Charge sponsorship12:45 Do I want to reach the longevity escape velocity16:40 Absorbing supplements through the skin18:40 Optimal level of testosterone for longevity22:50 Should you cycle supplements on and off27:26 How I managed to follow a healthy lifestyle in my 20s31:07 How much red light therapy can you do per day33:10 Role of stress in longevity39:35 What to do against smog and air pollution43:50 Training fast twitch muscle fibers instead of lifting weights48:30 My all out supplement stack 100 supplements ranked: https://youtu.be/W8DZbYyuDmA?si=-QhWReblSJGdNoyi

Jon Berner, MD PhD is a board certified Psychiatrist from Seattle with 27 years of experience. He's also published several scientific papers. Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland Timestamps:00:00 Intro00:20 Why Dr Berner became interested in lithium04:50 Lithium’s benefits in Alzheimer’s and dementia10:50 Lithium’s effects on mTOR and autophagy12:50 Bon Charge sponsorship13:40 Clinical evidence for lithium in dementia18:20 What’s the optimal dose for lithium26:25 Lithium for bipolar and hyperactive brains29:25 Lithium as potential treatment in neurodegeneration31:55 Lithium’s effects on kidneys34:20 Personal experience with taking lithium40:40 Is it safe to take lithium prophalactically over the counter47:55 Rapamycin synergy with lithium51:45 AI and human development Dr Berner's practice: https://www.woodinvillepsychiatric.com/ 100 supplements ranked: https://youtu.be/W8DZbYyuDmA?si=-QhWReblSJGdNoyi

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland Yip (Zico) Tszho is the Chief Executive of Lonvi Biosciences, a longevity-drug start-up, in Shenzhen, China. They're developing pharmaceuticals for extending human lifespan. We discuss their first senolytic called PCC1. Timestamps:00:00 Intro00:15 Articles about a pill making people live to 15002:50 What is PCC1 and how is it made07:10 How much can targeting senescence extend lifespan12:25 Bon Charge sponsorship13:15 Dose of PCC1 for senolytic and senomorphic effects18:30 PCC1 extending lifespan in mice by 9.4%23:20 Absorption rate of PCC1 and other senolytics27:10 Senolytics for young vs old age31:10 Human study on PCC134:40 What’s the optimal dose for senolytics38:05 Biomarkers of cell senescence40:10 Senolytic benefits on skin and retina46:35 What’s going on in Chinese longevity science52:10 Future direction of PCC1PCC1 studies: https://lonvibio.com/pages/science

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland Brady Holmer is a science writer and researcher with a Master's degree in Human Performance from the University of Florida Timestamps:00:00 Intro00:40 Why heat acclimation has performance benefits08:10 How to train heat acclimation12:40 Bon Charge sponsorship13:30 Benefits of the sauna for fitness18:25 Saunas and injury recovery22:30 Cold exposure and exercise performance26:45 Cooling down during and before exercise31:40 How often to train heat acclimation and sauna37:05 Sauna and HRV38:10 How long to stay in the sauna41:15 Electrolytes and dehydration acclimation46:25 Differences between men and women in heat acclimation47:00 Does heat acclimation have longevity benefits49:05 Does cold exposure have longevity benefits54:30 Which research should be done more on heat acclimation First podcast with Brady about VO2 max: https://youtu.be/xLDaFhN6h8I Brady Holmer Twitter: https://x.com/B_Holmer Brady Holmer website: https://www.bradyholmer.com/Start rewinding your biological clock: https://www.siimland.co/course

Join our upcoming retreat in January 2026: https://www.siimland.co/retreat Timestamps:Introduction (00:00)Discussion on longevity clinics and testing (01:52)Essential health tests and biomarkers (05:45)Improving VO2 Max and cardiovascular health (11:28)Blood tests and metabolic health (16:42)Hormone tests and longevity (21:35)Microbiome tests and toxicity (26:55)Microplastics and environmental toxicity (32:14)Food sensitivity testing (39:01)NAD testing and energy metabolism (41:50)Comprehensive health retreat (49:29) Dr. Joy Kong Youtube channel: https://www.siimland.co/retreat

Dr. Mark Tarnopolsky is a Professor and Division Head of Neuromuscular and Neurometabolic Disorders in the Department of Pediatrics at McMaster University. He completed a PhD in Cell Biology and Metabolism in 2001. Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland Timestamps:00:00 Intro00:25 What are mitochondria03:55 Mitochondria in aging and longevity06:00 Oxidative stress, inflammation, and longevity09:30 Antioxidants and benefits of exercise12:40 Bon Charge sponsorship13:30 Who should take antioxidants21:30 Mark’s antioxidant cocktail study24:30 Why is exercise the best thing for your mitochondria30:35 How endurance training shapes the mitochondria35:10 High intensity interval training36:50 Role of mitochondria in muscle loss42:00 Nutrition for mitochondrial health46:50 Supplements for mitochondrial health53:35 Stimulating mitophagy Dr Mark Tarnopolsky research page: https://scholar.google.com/citations?user=4jhi_KkAAAAJ&hl=en

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland Timestamps:00:00 Intro00:48 The genetics of a 117-year-old woman08:16 Resilience, immunity and longevity14:33 Muscle building genetics19:33 FOXO3 and stress resilience24:53 FOXO3 gene editing32:08 Can telomere lengthening be harmful to some individuals38:58 IGF-1 and growth hormone and longevity50:08 Genetically short sleepers54:38 What you should know about your longevity genes First podcast with Tyler about genetics and supplements: https://youtu.be/9GLbTEYewUs Tyler Panzner channel: https://www.youtube.com/@drtylerpanzner

Timestamps 0:00 – Introduction 4:12 – Humans adapt, and that changes the rules 9:58 – Diet diversity, sensitivities, and n of 1 16:51 – Assess first: biomarkers that predict disease risk 18:27 – Fixing sleep, movement, diet, environment 22:47 – Caution on rapamycin, metformin, methylene blue 25:54 – FOXO3 stem-cell study and what it means 37:15 – Mindset and willpower as real enhancers 41:44 – TMG, astaxanthin, melatonin, creatine 47:09 – VO2 max priorities and performance trade-offs 48:51 – Balancing fitness with joy and purpose 53:18 – Biomarkers mediate risk more than labels 1:01:00 – 2030–2040: what is realistic 1:04:02 – Immortality probabilities and living well now Julian Issa video podcast: https://youtu.be/vV8yMVGLG6Y?si=XiLxOx0bSSM-xT-v

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland Timestamps: 00:00 Does exercise increase inflammation 03:03 Melatonin megadosing research 04:23 NOVOS vs Blueprint VS DoNotAge 07:44 Hidden things that contribute to my health 12:14 Bon Charge sponsorship 13:05 How to improve night shift work 15:40 Supplements to take before the sauna 17:15 Does caffeine age the brain 19:34 Can you make up for lost sleep 20:40 Thoughts on Urolithin A 23:14 Doing too much for longevity 27:59 How to stop waking up at 3AM 30:57 How much sodium do I consume 33:20 Do sleep supplements blunt natural sleep 37:07 Inflammation in longevity 41:23 Importance of good relationship with food

Get my 2025 supplement guide: https://www.siimland.co/supplement-list-2025 Timestamps:00:00 Intro00:14 Taurine01:19 Apigenin01:55 Resveratrol03:20 Rapamycin04:55 Metformin06:11 Calcium AKG07:30 Melatonin08:16 SIRT609:05 NAC09:43 NMN, NR, Niacinamide11:10 Niacin13:58 Glycine15:16 Spermidine16:44 Omega-3s17:40 Creatine18:48 Pterostilbene19:19 Magnesium20:16 Vitamin K220:45 Sulforaphane21:34 Curcumin22:08 Methylated B vitamins22:33 Glutathione24:08 Lithium24:55 Lutein & Zeaxanthin25:30 Vitamin C26:29 Ergothioneine27:23 Methylene blue28:46 Multivitamin29:37 Aged garlic extract30:22 Astaxanthin31:06 TMG31:50 Ginger32:15 CoQ1032:53 PQQ33:24 Chondroitin33:45 MSM32:25 Glucosamine34:54 Conclusion 100 supplements ranked worst to best: https://youtu.be/W8DZbYyuDmA Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/

Chris Dancy is called 'the most connected man on Earth' because of his pioneering use of technology in everyday life and health optimization. Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland Timestamps:00:00 Intro00:23 Why Chris is the most connected man on earth03:38 How Chris used technology to lose weight and get healthy08:43 How technology changes the human experience in the future10:43 Best tools 16:28 The technology Renaissance period20:43 Bon Charge sponsorship21:38 Implants24:18 Hacking time33:28 Meditation and mindfulness36:48 Does time go by faster if you’re stuck in daily routines47:38 How Chris’ perception of time has changed as he got older52:43 Will virtual reality extend perception of lifespan59:03 How to make technology better for your health Chris Dancy website: https://www.chrisdancy.com/