Intention to Treat
Medical
From the New England Journal of Medicine, welcome to “Intention to Treat,” a podcast exploring the most complicated, perplexing, and fascinating issues facing medicine today. From groundbreaking research, to clinical advances, to personal stories from doctors and their patients, we give you a behind-the-scenes look at discoveries that are changing medical practice and provide you with the knowledge to thrive on the front lines of health care.
Location:
United States
Description:
From the New England Journal of Medicine, welcome to “Intention to Treat,” a podcast exploring the most complicated, perplexing, and fascinating issues facing medicine today. From groundbreaking research, to clinical advances, to personal stories from doctors and their patients, we give you a behind-the-scenes look at discoveries that are changing medical practice and provide you with the knowledge to thrive on the front lines of health care.
Language:
English
Episodes
CAR T-Cells and Safety Signals
4/24/2024
This episode examines CAR T-cell therapy’s early successes, broader promise, and emerging risks, as the FDA considers reports of occasional secondary cancers.
A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2400701.
Duration:00:25:25
Progress for Parkinson's?
4/3/2024
This episode explores the fastest-growing neurologic condition in the world, Parkinson’s disease. What have we learned in recent years, and where are the greatest hopes for the future?
A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2414003.
Duration:00:26:36
Doctors and Guns
3/13/2024
In this episode, parents who have lost children to gun accidents and physicians working for gun safety discuss the number-one killer of U.S. children and what doctors can do about it.
A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2314002.
Duration:00:25:38
Race Relations and the First Paramedics
2/28/2024
This episode of “Intention to Treat” tells the story of the Freedom House Ambulance Service — a group of Black laypeople in Pittsburgh who underwent intensive training to become the first paramedics in the United States. [Originally aired on May 4, 2023.]
A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2303614.
Duration:00:29:06
Why Doctors Need to Talk about Death
2/14/2024
Highlighting gaps in communication near the end of life, this podcast episode explores a new approach to preparing patients with serious illness and their families for all possible outcomes.
A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2314001.
Duration:00:23:41
Investigating Injustices in the Journal's History, Part 2
1/31/2024
In the second half of our podcast series on historical injustices, guests Evelynn Hammonds and David Jones examine the racism of post-World War II American medicine and its lessons for the present day.
A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2314000.
Duration:00:28:40
Investigating Injustices in the Journal's History
1/17/2024
Over its 200-plus years, the Journal has sometimes published articles that have perpetuated injustices against various groups of people. A new Perspective series explores that history and its lessons.
A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2311329.
Duration:00:21:31
Covid Update
12/20/2023
This episode examines Covid-19 variants that are currently circulating, recommendations for booster shots, and new treatments in the pipeline.
A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2311327.
Duration:00:41:19
Is Xenotransplantation Ready for Prime Time?
12/6/2023
This episode examines the need for and promise of xenotransplantation, considering first the plight of patients and then the progress being made by researchers.
A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2309946.
Duration:00:47:23
Alzheimer’s Update, Part 2
11/22/2023
This episode explores the current state of research on the multiple likely mechanisms of Alzheimer’s disease as well as promising treatments and diagnostics.
A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2309944.
Duration:00:54:00
Alzheimer’s Update, Part 1
11/8/2023
Host Rachel Gotbaum talks with a patient with early-onset Alzheimer’s disease and two dementia experts about frustrations with the current state of Alzheimer’s care.
A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2309485.
Duration:00:56:29
The Long Haul of Long Covid
10/11/2023
This episode explores long Covid, an often-disabling but unexplained syndrome of post-acute sequelae of SARS-CoV-2. How is it affecting millions of people, and what is being done about it?
A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2309483.
Duration:01:03:22
What We Don’t Know about School Shooter Drills
9/27/2023
This episode peers into U.S. schools to examine a widespread but non–evidence-based approach to preparing children and staff for gun-violence incidents.
A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2308309.
Duration:00:31:56
Awakened Hope for Narcolepsy
9/13/2023
In this episode, a patient with narcolepsy describes her rough, long road to diagnosis and treatment, and a researcher elucidates both the condition and a new therapeutic direction.
A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2308308.
Duration:00:32:35
Obesity and Heart Failure
8/25/2023
Cardiologists now recognize that heart failure with preserved ejection fraction (HFpEF) may be caused by obesity. This episode of “Intention to Treat” examines new evidence that treating obesity can prevent HFpEF.
A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2307349.
Duration:00:38:43
Preventing HIV’s Collateral Cardiovascular Damage
8/16/2023
People living with HIV have increased risk for cardiovascular disease (and other diseases of aging) earlier in life than those without HIV. In this episode of “Intention to Treat,” researcher Steven Grinspoon describes a new strategy for preventing collateral damage.
A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2307347.
Duration:00:50:40
Prospects for Pain
8/2/2023
Some types of pain have proven resistant to all available medications. In this episode of “Intention to Treat,” Rachel Gotbaum talks with a patient with neuropathic pain and a researcher exploring new sodium-channel blockers that offer promise for such patients.
A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2305759.
Duration:00:42:02
The Plight of Primary Care, Part 2
7/19/2023
What is driving U.S. physicians out of primary care — and keeping trainees from going into it in the first place? In this episode of “Intention to Treat,” host Rachel Gotbaum explores the breakdown of the system and possible ways to save it.
A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2305758.
Duration:00:53:25
The Plight of Primary Care, Part 1
7/5/2023
This episode of “Intention to Treat,” explores the crisis in primary care in the United States, as increasing numbers or primary care physicians leave the field — driven out by corporatization, growing time pressure, and the inability to form the relationships that enable good care.
A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2303852.
Duration:00:54:55
Unleashing CRISPR on Cancer
6/21/2023
In this episode of “Intention to Treat,” host Rachel Gotbaum explores the story of a teenager who’s now in remission from previously relapsed lymphoblastic leukemia and talks with the investigator who developed the “off-the-shelf” CAR T cells that made her treatment possible.
A full transcript of this episode is available at nejm.org/doi/full/10.1056/NEJMp2303851.
Duration:00:52:50