Going anti-Viral

Episode 16 - Insights on HIV Cure by Stem Cell Transplant with Dr Ravindra Gupta Recorded Live at CROI 2024 on March 3, 2024 In this episode of Going anti-Viral, Dr Michael Saag hosts Dr Ravindra Gupta. Dr Gupta is the infectious diseases expert who led the team that treated Adam Castillejo, also known as ‘The London Patient,' the second person known to have been cured of HIV. The discussion, recorded on March 3, 2024, at the Conference on Retroviruses and Opportunistic Infections (CROI), focused on the intricate process of finding a suitable stem cell donor, the immunologic and virologic considerations around the transplant process, and the collaborative medical team effort involved. 00:00 Introduction 00:30 The London Patient 03:05 Finding the CCR5∆32 Stem Cell Match 04:21 Clinical Challenges on the Transplant Journey 06:58 Post-Transplant Monitoring and Milestones 15:53 Reflecting on the Journey 18:51 Closing Thoughts and Acknowledgments __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube Instagram TikTok ...

In this episode of Going anti-Viral, host Dr Michael Saag interviews Adam Castillejo, known as the London patient, who is the second person to have been cured of HIV infection. The discussion, recorded on March 3, 2024, at The Conference on Retroviruses and Opportunistic Infections (CROI), touches on Adam's initial HIV diagnosis in London during the early 2000s, the societal stigma and personal impact of the diagnosis, and his dual battle with HIV and cancer. Adam shares the complex journey of his treatment, including the failure of initial interventions and the ultimate success of a bone marrow transplant from a donor with a CCR5 delta 32 mutation, leading to his cure of HIV and cancer. The conversation delves into the technical aspects of bone marrow transplant, the emotional and physical challenges Adam faced during recovery, and the continued stigma he experiences even post-cure. The episode reflects on the broader implications of Adam's story for HIV research and societal perceptions of the disease. 00:00 Introduction 01:10 Adam's Early Struggle with HIV Diagnosis 02:46 Confronting Stigma and Finding Support 05:26 The Battle Against Cancer and Mental Health Challenges 08:35 The Turning Point: Bone Marrow Transplant 15:14 The Journey of Recovery 17:29 Life After the Cure 22:37 Concluding Thoughts __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube Instagram TikTok ...

Episode 14 - HIV Treatment with Long-Acting Injectables with Dr Aadia Rana Recorded Live at CROI 2024 on March 4, 2024 In this episode, Dr Michael Saag and Dr Adia Rana discuss a breakthrough study on using a long-acting injectable HIV treatment with conditional economic incentives for individuals who were unable to take oral therapy. Presented at CROI 2024, the study's positive outcomes offer an effective option for certain individuals with no other options for continuing oral antiretroviral therapy. For further reading, please visit the link below. Updated Treatment Recommendation on Use of Cabotegravir and Rilpivirine for People With HIV From the IAS-USA Guidelines Panel 00:00 Introduction to the Podcast and Guest 00:50 Exploring Adherence Challenges and Study Insights 03:27 The Evolution of HIV Treatment: From Oral to Injectable Therapies 10:59 Study Results: A New Alternative for Select Individuals with Limited Treatment Options 16:05 Navigating Real-World Applications and Ethical Considerations 21:08 Reflecting on the Journey and Looking Ahead 25:21 Closing Thoughts and Future Directions __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube Instagram TikTok ...

Episode 13 - Advancements in STI Prevention: Insights from Dr Jean-Michel Molina Recorded Live at CROI 2024 on March 3, 2024 In this episode of Going anti-Viral, Dr Michael Saag and Dr Jean-Michel Molina discuss recent developments in STI prevention, focusing on doxycycline as post-exposure prophylaxis (DoxyPEP) and the evaluation of a meningococcal vaccine for gonorrhea prevention in the ANRS Doxyvac trial. Recorded at CROI 2024, Dr Molina shares insights from clinical trials, including challenges with data analysis and implications for future STI prevention and vaccine research. 00:00 Introduction to the Podcast and Guest 00:30 Innovative Approaches in Clinical Care with Dr Jean-Michel Molina 00:54 Exploring the Impact of Doxycycline and Vaccines on STIs 01:50 Challenges and Insights from Clinical Trials 04:29 The Journey from Interim Analysis to Final Results 09:27 Addressing Data Discrepancies 21:05 Future Directions in STI Prevention and Vaccine Research 26:46 Closing Thoughts and the Importance of Trustworthy Research __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube Instagram TikTok ...

Episode 12 - New Study on Treatments for Non-Alcoholic Fatty Liver Disease in People With HIV With Dr Jordan Lake Recorded Live from CROI 2024 In this episode, Dr Michael Saag speaks with Dr Jordan Lake live from the 2024 Conference on Retroviruses and Opportunistic Infections (CROI). They discuss the prevalence of non-alcoholic fatty liver disease (NAFLD) among people with HIV and explore the effectiveness of the GLP-1 receptor agonist semaglutide, commonly used to treat diabetes and aid in weight loss, to treat NAFLD. Future areas of research are considered, including maintenance strategies post-weight loss and a placebo-controlled version of the study. 00:02 Introduction and Welcome 00:44 Discussion on Non-Alcoholic Fatty Liver Disease in People With HIV 01:56 Role of HIV in Non-Alcoholic Fatty Liver Disease 02:43 Understanding the Inflammation and Fat Accumulation in the Liver 04:38 Exploring the Impact of Nucleoside Therapy on Non-Alcoholic Fatty Liver Disease 06:37 Potential Treatments for Non-Alcoholic Fatty Liver Disease 07:35 The Role of Semaglutide in Treating Non-Alcoholic Fatty Liver Disease 13:36 The Importance of Routine Assessment for Non-Alcoholic Fatty Liver Disease 15:37 Exploring New Drugs for Treating Non-Alcoholic Fatty Liver Disease 18:49 The Challenges and Future Directions in Non-Alcoholic Fatty Liver Disease Research 22:25 Conclusion and Closing Remarks __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube Instagram TikTok ...

Episode 11 - Innovations in Vaccine Research: Single Cell Immunity Development With Dr Fabian Otte Recorded Live from CROI 2024 In this podcast episode, Dr Michael Saag converses with Dr Fabian Otte, a molecular biologist at the University of Basel in Switzerland, live from the 2024 Conference on Retroviruses and Opportunistic Infections (CROI). Dr Otte shares insights into the ongoing development of an innovative SARS-CoV-2 vaccine that employs a single-cell immunity development approach. Highlighting its potential benefits, such as broader and longer-lasting immunity compared with mRNA vaccines. This pioneering vaccine research might also extend to other RNA viruses in the future. 00:02 Introduction to the Podcast and Guest 00:28 Discussion on the Development of Next-Generation SARS-CoV-2 Vaccines 00:50 Exploring a Single-Cell Immunity Approach 01:10 Understanding the Vaccine Development Process 02:42 The Potential of the New Vaccine 03:13 Challenges and Advantages of the New Vaccine 05:07 The Impact of the Vaccine on Immune Response __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube Instagram TikTok ...

Episode 10 - Harnessing the Power of Bacteriophages With Dr Robert Schooley In this podcast episode, host Dr Michael Saag speaks with Dr Robert “Chip” Schooley, a distinguished Professor of Medicine in the Division of Infectious Diseases and Global Public Health at the University of California San Diego. They discuss the revolutionary potential of bacteriophages, viruses that can infect and kill bacteria. They detail the research efforts and case studies involved in understanding the potential deployment of bacteriophages as a medical treatment. The discussion also highlights the necessity for clinical trials and future research involving genetically engineered phages. 00:02 Introduction and Guest Profile 01:51 The Growing Problem of Antimicrobial Resistance 02:55 Understanding Bacteriophages 04:21 The History and Use of Bacteriophages in Labs 05:45 The Role of Bacteriophages in Molecular Biology 11:43 The Journey of Treating a Patient with Bacteriophages 19:19 The Future of Bacteriophage Therapy 31:05 Closing Remarks and Podcast Outro __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube Instagram TikTok ...

Episode 9 - Understanding The Implementation of Doxycycline Post-Exposure Prophylaxis (DoxyPEP) and Addressing Sexually Transmitted Infections with Dr Annie Luetkemeyer In this episode of Going anti-Viral, Dr Michael Saag has an insightful discussion with Dr Annie Luetkemeyer, a professor of medicine in the Division of HIV, Infectious Diseases, and Global Medicine at Zuckerberg San Francisco General at the University of California San Francisco. Centering around the state of sexually transmitted infections in the United States, rising cases, strategies for control, and the promising role of doxycycline post-exposure prophylaxis (DoxyPEP) 00:02 Introduction to the Podcast 01:31 Discussion on the State of Sexually Transmitted Infections 05:21 Exploring the Concept of Post-Exposure Prophylaxis 07:19 Understanding the Implementation of DoxyPEP 10:23 Effectiveness of DoxyPEP 17:41 Potential Side Effects and Concerns of DoxyPEP 22:37 Future Prospects of DoxyPEP in STI Prevention 28:04 Conclusion and Final Thoughts 28:46 Podcast Closing Remarks __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube Instagram TikTok ...

Episode 8 - An Overview of The HIV/AIDS Epidemic, Prevention and Intervention Methods, and Future Strategies with Dr Susan Buchbinder In this episode of the Going anti-Viral podcast, host Dr Michael Saag speaks with Dr Susan Buchbinder, a professor of medicine, epidemiology, and biostatistics at the University of California, San Francisco. They discuss the HIV/AIDS epidemic, tracing its history from its rise in the early 80s to its current status. The conversation covers the efficacy of different preventive and treatment strategies, such as community engagement, behavioral changes, condom use, pre-exposure prophylaxis (PrEP), and the prospects of a future HIV vaccine. 00:02 Introduction to the Podcast 00:31 Guest Introduction: Dr Susan Buchbinder 01:10 History of the HIV Epidemic 05:01 The Role of Community in HIV Prevention 06:30 Prevention and Interventions 07:40 The Importance of HIV Testing 10:28 The Revolution of PrEP in HIV Prevention 12:42 The Challenges in Ending the HIV Epidemic 22:18 The Future of HIV Prevention 24:55 Conclusion and Final Thoughts __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube Instagram TikTok ...

Episode 7 - A Conversation With Dr Katelyn K. Jetelina About Her Journey in The Field of Epidemiology, The Initial Handling of The COVID-19 Pandemic, The Spreading of Misinformation, And The Urgent Need to Rebuild Public Trust in Health Infrastructure Recorded January 8, 2024. In this episode of Going anti-Viral, Dr Michael Saag speaks to epidemiologist Dr Katelyn K. Jetelina, co-founder of The Health Trust Initiative, and Senior Scientific Advisor to several government and non-profit agencies, including the White House, Centers for Disease Control and Prevention, and Resolve to Save Lives. The conversation, dated January 8, 2024, revolves around Dr Jetelina’s journey in the field of epidemiology, the initial handling of the COVID-19 pandemic, the spreading of misinformation, and the urgent need to rebuild public trust in health infrastructure. They also touch on the role of Artificial Intelligence (AI) in rapidly spreading misinformation for profit, and its potential to disseminate correct information. Dr Jetelina suggests that empowering community leaders with accurate scientific information and leveraging technologic innovations can play a key role in improving the public health system. 00:02 Introduction and Guest Presentation 01:09 Dr Jetelina's Journey Into Epidemiology 03:19 Understanding the Transmission of COVID-19 06:39 The Impact of COVID-19 and the Role of Public Health Officials 11:00 The Challenge of Misinformation and Disinformation 21:49 Addressing the Future: Preparing for the Next Pandemic 26:10 Conclusion and Final Remarks __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube Instagram TikTok ...

Episode 6 - A Conversation With Dr Anthony Fauci on His Career And His Role in the Responses to AIDS and COVID-19. Recorded December 14, 2023 Dr Michael Saag hosts Dr Anthony Fauci on this episode of the Going anti-Viral podcast, discussing Dr Fauci's career journey, his involvement in AIDS research, and his contribution towards managing other viral diseases. The conversation particularly focuses on the initial response to AIDS, the response to the COVID-19 pandemic, the vaccine development process, and the challenges and successes encountered. The podcast also highlights the significant shift in activism around public health crises, contrasting the constructive role of AIDS activists with the destructive anti-science activism faced during COVID-19. 00:02 Introduction and Background 00:42 Dr Anthony Fauci's Early Life and Career 02:07 Beginning of the AIDS Story 02:12 First Encounter with AIDS and Initial Response 03:34 The Turning Point in AIDS Research 04:16 Building the AIDS Research Team 12:04 The Role of Activism in AIDS Research 17:06 The Emergence of COVID-19 17:55 The Development of the COVID-19 Vaccine 25:58 The Challenges of Anti-Science Activism in the COVID-19 Era 29:29 The Future of Public Health Communication 30:28 Conclusion and Reflections __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube Instagram TikTok ...

Episode 5 - An In-depth Discussion on Syphilis With Dr Meredith Clement, Associate Professor at Louisiana State University Health Sciences Center. This special episode was recorded live from the 2023 Ryan White HIV/AIDS Program CLINICAL CONFERENCE in Portland, OR, on December 4th, 2023. In this special episode of Going anti-Viral, recorded live from the 2023 Ryan White HIV/AIDS Program CLINICAL CONFERENCE in Portland, OR, Dr Michael Saag speaks with Dr Meredith Clement, Associate Professor at Louisiana State University Health Sciences Center. They discuss the history and increasing prevalence of syphilis, the contributing factors to its resurgence, and its various stages. Dr Clement also highlights the current challenges in syphilis treatment, such as medication shortages and the need for rigorous screenings during prenatal care. 00:08 Introduction and Welcome 00:57 Discussing the History and Prevalence of Syphilis 01:40 Understanding the Decline of Syphilis in the 1990s 02:21 Current State of Syphilis Cases and Demographics 03:29 Challenges in Prenatal Care and Congenital Syphilis 07:05 Understanding the Stages of Syphilis 09:47 Diagnosis and Testing for Syphilis 13:53 Treatment Options for Syphilis 15:53 Challenges and Future Directions in Syphilis Treatment 22:41 Conclusion and Final Thoughts __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube Instagram TikTok ...

Episode 4 - A Deep Dive Into Vaccine Development With Dr Richard Koup, Deputy Director Chief, Immunology Laboratory Vaccine Research Center, NIAID, NIH. This special episode was recorded live from the 2023 Ryan White CLINICAL CONFERENCE in Portland, OR, December 2nd, 2023 In this special episode of Going anti-Viral, recorded live from the 2023 Ryan White CLINICAL CONFERENCE in Portland, OR, we explore the challenges and progress in developing vaccines for HIV and COVID-19. Dr Saag discusses with Dr Richard Koup, Deputy Director Chief, Immunology Laboratory Vaccine Research Center, NIAID, NIH, about vaccine development for HIV and its associated challenges and how pre-existing knowledge of similar viruses expedited COVID-19 vaccine development. The conversation also touches upon cellular immunity, broadly neutralizing antibodies, and the potential future of HIV vaccine development. 00:08 Introduction and Welcome 00:44 Interview with Dr Richard Koup 01:05 The History of HIV Vaccine Development 02:26 The Challenges of HIV Vaccine Development 06:33 The Role of Broadly Neutralizing Antibodies in HIV Vaccine Development 14:30 The Potential of Cellular Immunity in HIV Vaccine Development 16:08 The Miraculous Development of the COVID-19 Vaccine 26:37 The Future of HIV Vaccine Development 28:13 Conclusion and Closing Remarks __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube Instagram TikTok ...

Episode 1 - 40 Years Later: Looking Back at the Beginning of the HIV/AIDS Epidemic In this episode of Going anti-Viral, we revisit a panel discussion titled "40 Years Later: Looking Back at the Beginning of the HIV/AIDS Epidemic," sponsored by the IAS–USA. Dr Gerald Friedland moderates a panel of key medical figures who served at the frontlines of the HIV/AIDS epidemic during its early years. The panel, consisting of Dr Kathryn Anastos, Dr Donna Futterman, Dr Sheldon Landesman, and Dr Fred Valentine discusses their experiences, the systemic responses, and the stigma associated with the disease. They contemplate on how the lessons learned from HIV are relevant to the current COVID-19 pandemic and the potential pandemics that may come in the future. The discussion took place on June 13, 2022, at the Scott M. Hammer Annual Update on HIV Management in New York City. 00:00 Introduction and Overview of the Podcast 00:37 Panel Discussion: Reflecting on the Early Days of the HIV Epidemic 01:20 Panelists Share Their Personal Experiences and Challenges 02:29 The Impact of HIV on Medical Professionals and Their Careers 03:01 The Spread of HIV in Different New York City Boroughs 03:45 Panelists' Current Roles and Their Initial Encounters with HIV 06:01 The Struggle with Internalized Homophobia in HIV Patients 06:26 The Evolution of HIV Treatment and the Reaction of Medical Providers 07:44 The Emotional Impact of the HIV Epidemic 20:06 The Challenges of Creating a System of Care for HIV Patients 21:23 The Stigma and Misunderstandings Surrounding HIV 40:29 The Role of Activism in the Fight Against HIV 41:35 Institutional Responses to the HIV Epidemic 43:21 Challenges in Pediatric Care for HIV Patients 44:10 Stigma and Discrimination in Healthcare 44:47 International Efforts in HIV Testing 47:01 Safety Measures in HIV Research Labs 48:43 Health and Hospitals Corporation's Role in HIV Care 50:01 The Impact of HIV on Medical Education and Training 54:11 The Role of Activism in the HIV/AIDS Response 55:40 Lessons from HIV for Future Pandemics 57:16 The Response of the Medical Community to HIV 58:21 The Importance of Addressing Social Determinants of Health 01:00:08 The Future of HIV Research and Care 01:06:34 Closing Remarks and Reflections __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube Instagram TikTok ...

Episode 2 - Latest Update on Urgent Virus Outbreaks, August 2023 Dialogue on Urgent Viral Diseases This episode of Going anti-Viral features an IAS–USA Dialogue titled "Latest Update on Urgent Virus Outbreaks," which is a panel discussion held on August 1, 2023. Dr Paul A. Volberding from the University of California San Francisco serves as the moderator and welcomes three distinguished panelists: Dr Carlos del Rio from Emory University, Yvonne Maldonado from Stanford University and Dr Michael Saag from the University of Alabama Birmingham. discuss recent developments in COVID-19, MPOX, RSV, and HIV. This includes the the paradigm-shifting results of the REPRIEVE study, current hurdles in COVID-19 vaccination and antiviral treatment, and trends in RSV and MPOX. They also discuss the overall impact of COVID-19 on education and child development. 00:08 Introduction and Panel Discussion Overview 01:56 Discussion on the REPRIEVE Study 05:59 COVID-19 Updates and Vaccination Challenges 13:35 The Role of Antivirals in COVID-19 Treatment 20:39 Future of COVID-19 Vaccines and Age Group Considerations 27:20 The Importance of Transparency 28:18 The Need for Open Discussions on COVID-19 Vaccines 29:47 The Existential Threat to Science-Based Medicine 31:49 The Challenge of Testing for RSV 33:11 The Potential Impact of RSV Vaccines 36:45 The Ongoing Struggle with Long COVID-19 42:46 The Increasing Cases of MPOX 48:27 The Tragic Impact of the Pandemic on Education 53:42 The Importance of In-Person Interactions 54:10 Closing Remarks __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube Instagram TikTok ...

Episode 3 - Latest Update on Emerging And Reemerging Urgent Viral Outbreaks, Including COVID-19, MPOX, And Flu. October 2023 In today's episode of Going anti-Viral, we present a recent dialogue from October 19th, 2023, with special guest Katelyn K. Jetelina, MPH, PhD. Dr Jetelina is an epidemiologist, data scientist, and author of the popular newsletter "Your Local Epidemiologist (YLE)". She joined moderator Paul Volberding, MD, and discussants Peter Chin-Hong, MD, and Carlos del Rio, MD, for a lively discussion on the latest hot-button issues in the field of infectious diseases. Key conversations focus on the state of the COVID-19 pandemic, the role of vaccines and the growing issues related to insufficient data when tracking and treating viral infections. The discussion further extends to examine the political backlash that threatens institutional trust, pushing for a stronger approach that involves community-based contributions to conquering infectious diseases. 00:08 Introduction and Guest Presentation 01:16 Guest Introductions and Backgrounds 04:48 Discussion on Current Infectious Disease Trends 09:14 The Role of Data in Tracking Disease Trends 12:30 The Politics of Public Health Data 16:41 The Impact of Politics on Vaccination 16:54 Vaccination Discussion: COVID-19, Influenza, and RSV 26:20 Influenza Season Discussion 28:24 Discussion on Vaccination Coverage and Data Collection 30:30 The Importance of Vaccination Timing and Convenience 31:33 Understanding RSV in Adults and Its Diagnosis 32:28 The Importance of Testing and the Impact of COVID-19 on Testing Practices 33:13 The Challenge of Distinguishing Between Different Respiratory Infections 34:27 Discussion on Influenza Vaccines and Their Effectiveness 36:08 The Importance of Vaccination and Addressing Vaccine Hesitancy 43:55 The Future of Vaccines 09:10 Addressing the Challenges of Misinformation and Trust in Public Health __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube Instagram TikTok ...

Introducing Going anti-Viral, the podcast of the IAS–USA, a professional continuing medical education organization focused on HIV and other viral diseases. I’m Dr Michael Saag, professor emeritus of medicine and infectious diseases at the University of Alabama at Birmingham and volunteer member of the IAS–USA Board of Directors. Join us as we interview experts in viral medicine about their area of specialty and current developments in the field. Other episodes are drawn from the IAS-USA vast catalogue of panel discussions, Dialogues, and various meetings and conferences. Going anti-Viral is a podcast series for clinicians, produced by the International Antiviral Society–USA. The IAS–USA is a not-for-profit professional organization committed to improving the treatment, care, and quality of life for people with or at risk for HIV or other viral infections and their complications through balanced education and information. This podcast is intended as a technical source of information for specialists in this field, but we hope anyone listening will enjoy learning more about the state of modern medicine around viral infections and their consequences. __________________________________________________ Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode. Follow Going anti-Viral on: Apple Podcasts YouTube Instagram TikTok ...