Evolution 2.0

Jay Cross interviews me about my new paper, The Reasonable Ineffectiveness of Mathematics in the Biological Sciences (co-authored with Sy Garte and Stuart Kauffman.) Together we explore why “there are no equal signs in biology,” how this revelation redefines medicine as we know it, and the post-computational, post-permission future of healing—with new hope for people facing serious health challenges. Jay is an accomplished direct response copywriter and researcher with great interest in the “third transition” in science, and this conversation opens that up in a big way. Hosted on Acast. See acast.com/privacy for more information.

Perry describes a series of life-changing "thin place" experiences that shifted his reality. This was presented to Adam Safron's Sapience group, followed by a guided meditation and a Q&A at the end. A further expansion on these ideas is online at perrymarshall.com/ireland. Hosted on Acast. See acast.com/privacy for more information.

Sy Garte's book, Beyond Evolution, is written for the person who is trying to reconcile their deep yearnings for meaning and significance with the longstanding scientific dogma that nature has no purpose. Not only is the tide shifting dramatically inside of secular science, the new discoveries are connecting gaps between the many factions and divisions within the religious world. Sy Garte Email: sygarte@gmail.com [mailto:sygarte@gmail.com] Website: https://sygarte.com/ Substack: https://sygarte.substack.com/ Pre-order Beyond Evolution on Amazon [https://www.amazon.com/Beyond-Evolution-Discoveries-Science-Point/dp/B0DJY6PY7H] Hosted on Acast. See acast.com/privacy for more information.

What happens when researchers from competing scientific worldviews sit down for an honest conversation? In this dialogue, three thinkers—exploring Neo-Darwinism, Third Way evolution, and Intelligent Design—discover unexpected common ground while respecting disagreements. Denis Noble (Oxford University, Third Way evolution, www.thethirdwayofevolution.com), Casey Luskin (Discovery Institute, Intelligent Design, www.evolutionnews.org), and Perry Marshall (Evolution 2.0, bridge-builder, www.evo2.org) engage in the kind of scientific discourse that's increasingly rare: genuine curiosity about opposing viewpoints without the usual academic tribalism. This isn't just another evolution debate. It's a case study in how scientists engage across ideological divides to advance understanding. The most profound insights often emerge not from echo chambers, but from healthy tension between opposing ideas. "We don't substitute any certainties whatsoever... let it evolve. Let us find out, let us, for God's sake, be open to what it might be that we discover." Denis Noble Transcript: https://evo2.org/wp-content/uploads/2025/07/Bridging-Evolution-A-Conversation-Between-Intelligent-Design-and-Third-Way-transcript.pdf Hosted on Acast. See acast.com/privacy for more information.

What happens when researchers from competing scientific worldviews sit down for an honest conversation? In this dialogue, three thinkers—exploring Neo-Darwinism, Third Way evolution, and Intelligent Design—discover unexpected common ground while respecting disagreements. Denis Noble (Oxford University, Third Way evolution, www.thethirdwayofevolution.com), Casey Luskin (Discovery Institute, Intelligent Design, www.evolutionnews.org), and Perry Marshall (Evolution 2.0, bridge-builder, www.evo2.org) engage in the kind of scientific discourse that's increasingly rare: genuine curiosity about opposing viewpoints without the usual academic tribalism. This isn't just another evolution debate. It's a case study in how scientists engage across ideological divides to advance understanding. The most profound insights often emerge not from echo chambers, but from healthy tension between opposing ideas. "We don't substitute any certainties whatsoever... let it evolve. Let us find out, let us, for God's sake, be open to what it might be that we discover." Denis Noble Transcript: https://evo2.org/wp-content/uploads/2025/07/Bridging-Evolution-A-Conversation-Between-Intelligent-Design-and-Third-Way-transcript.pdf Hosted on Acast. See acast.com/privacy for more information.

Andrew Briggs started to write the book Human Flourishing just before COVID and then the world went mad. Since then, the world has gotten even madder and many people are clutching their smartphones, wringing their hands, managing their anxiety, or merely existing. What does it mean to flourish and what do people, relationships, and professions look like and feel like when they flourish? In this book, authors Andrew Briggs and Michael J. Reiss and painter Roger Wagner weave together a beautiful picture of the material and immaterial, the concrete and the spiritual. Included here is a reproduction of Roger Wagner's painting It Keeps Me Seeking. The original painting hangs in The Auckland Project Faith Museum: https://aucklandproject.org/attraction/faith-museum/ Hosted on Acast. See acast.com/privacy for more information.

Andrew Briggs started to write the book Human Flourishing just before COVID and then the world went mad. Since then, the world has gotten even madder and many people are clutching their smartphones, wringing their hands, managing their anxiety, or merely existing. What does it mean to flourish and what do people, relationships, and professions look like and feel like when they flourish? In this book, authors Andrew Briggs and Michael J. Reiss and painter Roger Wagner weave together a beautiful picture of the material and immaterial, the concrete and the spiritual. Included here is a reproduction of Roger Wagner's painting It Keeps Me Seeking. The original painting hangs in The Auckland Project Faith Museum: https://aucklandproject.org/attraction/faith-museum/ Hosted on Acast. See acast.com/privacy for more information.

Derek Dearden from the UK and Perry Marshall discuss how to hold deeply held beliefs while also making space for people with widely differing views. Hosted on Acast. See acast.com/privacy for more information.

Tim Howard interviews me and Sy Garte about our new paper with Stuart Kauffman, The Reasonable Ineffectiveness of Mathematics in the Biological Sciences. Join us for a fascinating discussion about a new revolution underfoot in biology: Hosted on Acast. See acast.com/privacy for more information.

Two of my favorite scientists, Michael Levin and Azra Raza with Aastha Jain Simes, put their heads together in this provocative and touching interview. Azra describes the technology of our new company PredictRX that detects cancer at Stage Negative One. We do this with a “Stentinel,” (starts at 15 minutes in) a stent with electronic sensors that is implanted in the arm and sense Polyploid Giant Cancer Cells (PGCCs) within 18 days of appearing in a patient. Azra begins with an unusual definition of cancer and offers a detailed theory of Hybrid Cells based on her 35 years treating patients. This is a heart-gripping conversation. “If you find a single giant cell in a patient who’s in remission, a 2nd cancer is inevitable.” Hosted on Acast. See acast.com/privacy for more information.

She's 86, yet she looks like she's in her 60s. After 35 years of Myelodysplastic Syndrome, she is still beating the odds every day. In our conversation, she explains her radical outlook and her success under the watchful eye of oncologist Dr. Azra Raza at Columbia University in New York City. To learn more about Azra's work, visit www.reversingcancer.org or contact John Correll jon@reversingcancer.org. Hosted on Acast. See acast.com/privacy for more information.

Edward Kelly is a neuroscientist whose research overturns the current popular definition of the mind. We had a fantastic conversation about his non-traditional path in scientific research. He is a scientist at the University of Virginia. Hosted on Acast. See acast.com/privacy for more information.

Why are important conversations so difficult, and why is curiosity the greatest virtue? Dov Baron from British Columbia describes the emotional source code rules that govern our discussions about politics, religion, evolution, cancer, and relationships. Dov Baron has a unique ability to stab at the roots of a problem and recognize its signature pattern. It’s amazing to watch him problem-solve in real-time, and he’s famous for navigating difficult conversations. His website is dovbaron.com. Hosted on Acast. See acast.com/privacy for more information.

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Perry Marshall spoke at the Society for Brain Mapping and Therapeutics 21st annual conference in Los Angeles, 16 March 2024. He describes how outdated textbook evolution is inhibiting research and keeping us stuck in the old, gene-centric paradigm, and how the Polyploid Giant Cancer Cell model, advocated at a recent conference at MD Anderson in Houston, is a far more elegant model for detecting and treating cancer at the very earliest stages. Hosted on Acast. See acast.com/privacy for more information.

EXACTLY 20 years ago this week, I flew to China to see my brother Bryan. We got into an argument on a bus (a story I’ve told 1000 times). He was bailing on his missionary career and his entire Christian upbringing, and I found this deeply upsetting. Odds are you’ve heard my version of the story: the Evolution 2.0 book and prize, my work in virology and cancer research, and the 1/3 of my life I spent as a member of the science community. It has redefined my life. People always ask how this turned out for Bryan. Odds are you have NOT heard his side of the story! You might be surprised how attentively he has watched as this has unfolded. www.coffeehousetheology.com https://evo2.org/meeting-grendels-mother-in-the-spiritual-swamp/ www.evo2.org/bryan Books on Amazon "Understanding Living Systems" by Denis and Ray Noble "Evolution 2.0" by Perry Marshall "Master and his Emissary" by Iain McGilchrist Hosted on Acast. See acast.com/privacy for more information.

Well-known biologist and author Sy Garte, author of the new book “Science and Faith in Harmony” joins Perry. They explore the alignment between science and faith and probe purpose in biology. They discuss the challenges of applying mathematical concepts to biological systems, recognizing that EVERY rule in biology has an exception. The two discuss changing norms in academic discourse, the new journal Biocosmos and "The Unreasonable Ineffectiveness of Mathematics in the Life Sciences.” Sy's book: https://amzn.to/49px5MD Sy's website: www.sygarte.com Sy's X feed: x.com/sygarte Hosted on Acast. See acast.com/privacy for more information.

"The Open Source Tissue Search Engine". This "Tissue Search Engine" will allow us to detect the early evolution of cancer -- THE KEY to reversing it. And this is why we should all be so excited by its breakthrough potential. The best part? With a little bit of help from you... We'll be intercepting hundreds of patients with early-stage, treatable cancers in 12 months! Hosted on Acast. See acast.com/privacy for more information.

What does quantum physics have to do with business decision-making, art, and AI? Perry Marshall spoke to Brian Kurtz’s Titans group in Connecticut in April and covered a dizzying range of topics from quantum physics to ChatGPT and the real problems of AI that no one seems to be talking about. Titans Xcelerator (www.briankurtz.net/xl) Hosted on Acast. See acast.com/privacy for more information.

Bob Regnerus digs into the real story behind Azra Raza's day long fireside chat in Vancouver, British Columbia Sept 23 & 24, 2023. Full information at evo2.org/vancouver. Hosted on Acast. See acast.com/privacy for more information.