Xavier B plays a wide variety of music. The time period he generally focuses on is from the 1950s through the mid 2000s. However, he's been known to go back further in time when the situation calls for it. Each week's show is based on a theme, artist, genre or era of music. He plays artists as diverse as The Temptations, R.E.M., Nina Simone, Public Enemy, The Andrews Sisters, and Garth Brooks. Along with the hits, Xavier B also features songs/artists that don't get a lot of airplay.