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ReachMD

Welcome to On the Frontlines of Multiple Sclerosis, a ReachMD series with the latest education and information on diagnostic and prognostic advancements and treatment options for patients with Multiple Sclerosis.

Welcome to On the Frontlines of Multiple Sclerosis, a ReachMD series with the latest education and information on diagnostic and prognostic advancements and treatment options for patients with Multiple Sclerosis.
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Location:

United States

Networks:

ReachMD

Description:

Welcome to On the Frontlines of Multiple Sclerosis, a ReachMD series with the latest education and information on diagnostic and prognostic advancements and treatment options for patients with Multiple Sclerosis.

Language:

English


Episodes

How Childhood Food Allergies Impact Public Health

12/5/2018
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Guest: Ruchi Gupta, MD, MPH Despite the increasing prevalence of food allergies in children nationwide, accurate and comprehensive statistics regarding its impacts didn’t exist, which is exactly why The Public Health Impact of Parent-Reported Childhood Food Allergies in the United States study was conducted. Here to walk us through its findings is Dr. Ruchi Gupta, Professor of Pediatrics at Northwestern University’s Feinberg School of Medicine and lead author of the study.

Duration:00:04:29

Is There a Link Between IUD Use & Breast Cancer Risk?

4/27/2018
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This episode of Audio Abstracts reviews two studies conducted in Finland that investigated the link between premenopausal use of hormonal intrauterine treatment for menorrhagia and breast cancer incidence rates. The first study, Cancer Risk in Women Using the Levonorgestrel-Releasing Intrauterine System in Finland, examined the incidence rates of several common cancers among intrauterine treatment users. The authors found that the risk of breast cancer increased within this patient...

Duration:00:05:00

Cervical Cancer Screening: The Latest Research on the Impact of Different Cytology Methods

1/16/2018
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Comparing SurePath, ThinPrep, and conventional cytology as primary test method: SurePath is associated with increased CIN II+ detection rates. Rozemeijer K, Penning C, Siebers AG, Naber SK, Matthijsse SM, van Ballegooijen M, van Kemenade FJ, de Kok IM. Cancer Causes Control. 2016 Jan;27(1):15-25.doi: 10.1007/s10552-015-0678-1. Epub 2015 Oct 12. Background Information: In the previous audio abstract summarizing the results from these researchers from the Erasmus Medical Center in the...

Duration:00:03:29

Infliximab Trough Levels at Induction to Predict Treatment Failure During Maintenance

1/2/2018
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Infliximab Trough Levels at Induction to Predict Treatment Failure During Maintenance. Liefferinckx C1, Minsart C, Toubeau JF, Cremer A, Amininejad L, Quertinmont E, Devière J, Gils A, van Gossum A, Franchimont D. BACKGROUND: Infliximab (IFX) is indicated for the treatment of inflammatory bowel diseases (IBD). Nevertheless, loss of response (LOR) to IFX is reported in up to 10% to 30% of patients within the first year of treatment. Our objective was to evaluate the impact of the...

Duration:00:04:29

Anti-TNF Treatment for Extraintestinal Manifestations of Inflammatory Bowel Disease in the Swiss IBD Cohort Study

10/30/2017
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Anti-TNF Treatment for Extraintestinal Manifestations of Inflammatory Bowel Disease in the Swiss IBD Cohort Study. Vavricka SR1, Gubler M, Gantenbein C, Spoerri M, Froehlich F, Seibold F, Protic M, Michetti P, Straumann A, Fournier N, Juillerat P, Biedermann L, Zeitz J, Misselwitz B, Scharl M, Heinrich H, Manser CN, Safroneeva E, Raja Ali RA, Rogler G, Schoepfer AM, Greuter T; Swiss IBD Cohort Study Group. BACKGROUND: Extraintestinal manifestations (EIMs) in patients with inflammatory...

Duration:00:06:29

Anti-TNFα Treatment After Surgical Resection for Crohn's Disease Is Effective Despite Previous Pharmacodynamic Failure

7/28/2017
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Anti-TNFα Treatment After Surgical Resection for Crohn's Disease Is Effective Despite Previous Pharmacodynamic Failure Assa A1, Bronsky J, Kolho KL, Zarubova K, de Meij T, Ledder O, Sladek M, van Biervliet S, Strisciuglio C, Shamir R. BACKGROUND: The outcome of patients with Crohn's disease who failed anti-tumor necrosis factor alpha (anti-TNFα) therapy despite adequate serum drug levels (pharmacodynamic failure) is unclear. We aimed to assess such pediatric patients who underwent...

Duration:00:05:59

Vedolizumab as Induction and Maintenance Therapy for Crohn’s Disease in Patients Naïve to or Who Have Failed Tumor Necrosis Factor Antagonist Therapy

5/4/2017
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Vedolizumab as Induction and Maintenance Therapy for Crohn's Disease in Patients Naïve to or Who Have Failed Tumor Necrosis Factor Antagonist Therapy. Sands BE1, Sandborn WJ, Van Assche G, Lukas M, Xu J, James A, Abhyankar B, Lasch K. BACKGROUND: Vedolizumab is a gut-selective α4β7 integrin antagonist for the treatment of moderately to severely active Crohn's disease (CD). Aims of this study were to characterize the efficacy and safety of vedolizumab induction and maintenance therapy in...

Duration:00:04:30

Predictors of Emergency Department Use by Persons with Inflammatory Bowel Diseases: A Population-Based Study

2/27/2017
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Predictors of Emergency Department Use by Persons with Inflammatory Bowel Diseases: A Population-based Study Nugent, Zoann PhD; Singh, Harminder MD, MPH; Targownik, Laura E. MD; Strome, Trevor MS; Snider, Carolyn MD, MPH; Bernstein, Charles N. MD Background: To describe the patterns and predictors of emergency department (ED) attendance and post-ED hospitalization by persons with inflammatory bowel disease (IBD). Methods: We linked the University of Manitoba IBD Epidemiology Database with...

Duration:00:04:30

The Burden of Bacterial Vaginosis and Women’s Experiences with Clinical Care

1/20/2017
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Guest: Caroline Mitchell, MD, MPH The Burden of Bacterial Vaginosis: Women’s Experience of the Physical, Emotional, Sexual and Social Impact of Living with Recurrent Bacterial Vaginosis Jade E. Bilardi, Sandra Walker, Meredith Temple-Smith, Ruth McNair, Julie Mooney-Somers, Clare Bellhouse, Christopher K. Fairley, Marcus Y. Chen, Catriona Bradshaw Bilardi JE, Walker S, Temple-Smith M, McNair R, Mooney-Somers J, et al. (2013) The Burden of Bacterial Vaginosis: Women’s Experience of the...

Duration:00:05:30

Impact of Specialized Inpatient IBD Care on Outcomes of IBD Hospitalizations

10/31/2016
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Impact of Specialized Inpatient IBD Care on Outcomes of IBD Hospitalizations: A Cohort Study Law, Cindy C. Y. MD; Sasidharan, Saranya MD; Rodrigues, Rodrigo MD; Nguyen, Deanna D. MD; Sauk, Jenny MD; Garber, John MD; Giallourakis, Cosmas MD; Xavier, Ramnik MD, PhD; Khalili, Hamed MD, MPH; Yajnik, Vijay MD, PhD; Ananthakrishnan, Ashwin N. MD, MPH Host: Dr. Manish Singla, Gastroenterology Division, Department of Internal Medicine, Walter Reed National Military Medical Center, Bethesda, MD...

Duration:00:03:29

Tissue-Specific Protein Clusters May Help Predict Risk of Alzheimer’s Disease

10/25/2016
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A protein homeostasis signature in healthy brains recapitulates tissue vulnerability to Alzheimer’s disease Rosie Freer, Pietro Sormanni, Giulia Vecchi, Prajwal Ciryam, Christopher M. Dobson, and Michele Vendruscolo Science Advances 10 Aug 2016: Vol. 2, no. 8, e1600947 DOI: 10.1126/sciadv.1600947 Abstract: In Alzheimer’s disease, aggregates of Aβ and tau in amyloid plaques and neurofibrillary tangles spread progressively across brain tissues following a characteristic pattern, implying a...

Duration:00:02:59

Dry Eye Disease: Effect of Re-esterified Omega-3 Supplementation

10/14/2016
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Effect of Oral Re-esterified Omega-3 Nutritional Supplementation on Dry Eyes Alice T. Epitropoulos, MD, Eric D. Donnenfeld, MD, Zubin A. Shah, MPH, Edward J. Holland, MD, Michael Gross, MD, William J. Faulkner, MD, Cynthia Matossian, MD, Stephen S. Lane, MD, Melissa Toyos, MD, Frank A. Bucci, Jr, MD, and Henry D. Perry, MD Cornea Volume 35, Number 9, September 2016 Abstract: Purpose: To assess the effect of oral re-esterified omega-3 fatty acids on tear osmolarity, matrix...

Duration:00:05:29

Cell Death and Differentiation: A Novel Treatment of Cystic Fibrosis Acting On-Target

8/1/2016
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A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR. Tosco A, De Gregorio F, Esposito S, De Stefano D, Sana I, Ferrari E, Sepe A, Salvadori L, Buonpensiero P, Di Pasqua A, Grassia R, Leone CA,Guido S, De Rosa G, Lusa S, Bona G, Stoll G, Maiuri MC, Mehta A, Kroemer G, Maiuri L, Raia V. Cell Death Differ. 2016 Aug;23(8):1380-93. doi: 10.1038/cdd.2016.22. Epub 2016 Apr 1. AbstractWe...

Duration:00:03:30

Journal of Cystic Fibrosis: Microbial Colonization and Lung Function in Adolescents With Cystic Fibrosis

8/1/2016
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Microbial colonization and lung function in adolescents with cystic fibrosis. Hector A, Kirn T, Ralhan A, Graepler-Mainka U, Berenbrinker S, Riethmueller J, Hogardt M, Wagner M, Pfleger A, Autenrieth I, Kappler M, Griese M, Eber E, Martus P, Hartl D. J Cyst Fibros. 2016 May;15(3):340-9. doi: 10.1016/j.jcf.2016.01.004. Epub 2016 Feb 5. Abstract With intensified antibiotic therapy and longer survival, patients with cystic fibrosis (CF) are colonized with a more complex pattern ofbacteria and...

Duration:00:02:30

Journal of Cystic Fibrosis: Efficacy and Safety of Levofloxacin Inhalation Solution (APT-1026) in Stable Cystic Fibrosis Patients

8/1/2016
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A phase 3, multi-center, multinational, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of levofloxacin inhalation solution (APT-1026) in stable cystic fibrosis patients. Flume PA, VanDevanter DR, Morgan EE, Dudley MN, Loutit JS, Bell SC, Kerem E, Fischer R, Smyth AR, Aaron SD, Conrad D, Geller DE,Elborn JS. J Cyst Fibros. 2016 Jul;15(4):495-502. doi: 10.1016/j.jcf.2015.12.004. Epub 2016 Feb 4. Abstract RATIONALE: For patients with cystic fibrosis...

Duration:00:03:30

Individual Detection of 14 High-risk HPV Genotypes by the PapType Test for the Prediction of High-grade Cervical Lesions

7/29/2016
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Individual detection of 14 high risk human papilloma virus genotypes by the PapType test for the prediction of high grade cervical lesions. Cuzick J, Ho L, Terry G, Kleeman M, Giddings M, Austin J, Cadman L, Ashdown-Barr L, Costa MJ, Szarewski A. J Clin Virol. 2014 May;60(1):44-9. doi: 10.1016/j.jcv.2014.02.002. Epub 2014 Feb 14. Abstract BACKGROUND: HR HPV genotypes when assayed collectively, achieve high sensitivity but low specificity for the prediction of CIN2+. Knowledge of the...

Duration:00:05:30

A study of HPV typing for the management of HPV-positive ASC-US cervical cytologic results

7/28/2016
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Host: Thomas C. Wright, Jr., MD A study of HPV typing for the management of HPV-positive ASC-US cervical cytologic results. Schiffman M, Vaughan LM, Raine-Bennett TR, Castle PE, Katki HA, Gage JC, Fetterman B, Befano B, Wentzensen N. Gynecol Oncol. 2015 Sep;138(3):573-8. doi: 10.1016/j.ygyno.2015.06.040. Epub 2015 Jul 4. Abstract BACKGROUND: In US cervical screening, immediate colposcopy is recommended for women with HPV-positive ASC-US(equivocal) cytology. We evaluated whether partial...

Duration:00:04:29

The Lancet: Postural Modification to the Standard Valsalva Maneuver for Emergency Treatment of Supraventricular Tachycardias (REVERT)

9/4/2015
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Postural modification to the standard Valsalva manoeuvre for emergency treatment of supraventricular tachycardias (REVERT): a randomised controlled trial Andrew Appelboam, FRCEM, Adam Reuben, FRCEM, Clifford Mann, FRCEM, James Gagg, FRCEM, Prof Paul Ewings, PhD, Andrew Barton, MSc, Trudie Lobban, MRCP, Mark Dayer, FRCP, Jane Vickery, MSc, Prof Jonathan Benger, MD on behalf of the REVERT trial collaborators The Lancet. 2015; DOI:10.1016/S0140-6736(15)61485-4 Published Online: 24 August 2015...

Duration:00:03:00

NEJM: Outcomes of Daytime Procedures Performed by Attending Surgeons after Night Work

9/4/2015
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Outcomes of Daytime Procedures Performed by Attending Surgeons after Night Work Anand Govindarajan, M.D., David R. Urbach, M.D., Matthew Kumar, M.Sc., Qi Li, M.Sc., Brian J. Murray, M.D., David Juurlink, M.D., Ph.D., Erin Kennedy, M.D., Ph.D., Anna Gagliardi, Ph.D., Rinku Sutradhar, Ph.D., and Nancy N. Baxter, M.D., Ph.D. N Engl J Med 2015; 373:845-853 DOI: 10.1056/NEJMsa1415994 August 27, 2015 Background: Sleep loss in attending physicians has an unclear effect on patient outcomes. In...

Duration:00:03:29

JAMA: Noninvasive Prenatal Testing and Incidental Detection of Occult Maternal Malignancies

9/4/2015
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Noninvasive Prenatal Testing and Incidental Detection of Occult Maternal Malignancies Diana W. Bianchi, MD; Darya Chudova, PhD; Amy J. Sehnert, MD; Sucheta Bhatt, MD; Kathryn Murray, MS; Tracy L. Prosen, MD; Judy E. Garber, MD; Louise Wilkins-Haug, MD, PhD; Neeta L. Vora, MD; Stephen Warsof, MD; James Goldberg, MD; Tina Ziainia, MD; Meredith Halks-Miller, MD JAMA. 2015;314(2):162-169. doi:10.1001/jama.2015.7120 Importance: Understanding the relationship between aneuploidy detection on...

Duration:00:04:29