LONGEVITY with Nathalie Niddam

In this episode, I sit down with Dr. Ian White—one of the most exciting researchers in regenerative medicine today. If you’re even a little bit curious about how to hack aging or have heard the buzz about things like plasma exchanges, exosomes, or why on earth lobsters never seem to grow old, you’re in for a treat. What we discuss: Expanding autologous hematopoietic stem cells and FDA challenges ... 00:08:28 Heterochronic parabiosis, plasma exchange, and aging signals ... 00:17:35 Nature’s clues: Lobsters, jellyfish, and biological age reset ... 00:24:02 Entropy, epigenetics, and limiting factors in aging ... 00:27:56 Vision: Youthful healthspan, not just longer lifespan ... 00:32:43 Amniotic fluid as a source of rejuvenation ... 00:36:01 Therapeutic results: burns, ulcers, and immune modulation ... 01:03:18 Exosomes vs. stem cells: Definitions and market problems ... 01:02:31 How exosomes function and the importance of source ... 00:51:23 Ensuring safe and effective regenerative therapies ... 01:00:10 Guidance for patients interested in exosome therapy ... 01:09:42 Dr. White’s research legacy and goals ... 01:14:04 Our Amazing Sponsors: Troscriptions - Blue Cannatine - think of it as a small but mighty brain boost that melts in your mouth. A precise blend of methylene blue, caffeine, CBD, and microdosed nicotine gives me steady energy, focus, and mental clarity without the usual ups and downs. Try it for yourself at troscriptions.com and use code NAT10 for 10% off. Get in the zone and stay there. NEW Timeline Gummies: Urolithin A supports muscle strength and cellular energy. It’s about improving how your body functions at the source. Mitopure is the only clinically proven Urolithin A, giving you six times more than you’d get from a glass of pomegranate juice. Visit Timeline.com/nat20 and use code nat20 for 20% off your purchase. Berberine Breakthrough - Take 15 min. before a meal and your body will push carbs and glucose into your muscles to be used as fuel instead of turning them into fat. Enjoy more stable energy without the post-meal crash. Visit bioptimizers.com/bionat and enter the code BIONAT to get 10% off your order. More from Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

Today, I've got something special for you: a solo episode where I look back at the past six months and handpick the five episodes and ideas that truly changed the game for me—and, based on your feedback, for many of you too. Episodes from this podcast: #300: Breast Cancer Overdiagnosis, Mammogram Myths, The REAL Risks For Women And Bold NEW Alternatives With Dr. Jenn Simmons #302: If You Have Creeky or Painful Joints and BIG Dreams of Staying Active, These Nonsurgical Solutions Are The NEW Way Forward - With Dr. Jeff Gross #309: Cordycepin and Methylene Blue: Two Game-Changers For Better Energy, Focus, Sleep, and So Much More With Dr. Scott Sherr #312: Age-Defying Bone Health: Preventing Osteoporosis with Science-Backed Interventions and Reversal Techniques You Can Try TODAY With Doug Lucas #318: Lies He Taught In Medical School: The METABOLIC Secret To Reversing Chronic Disease with Dr. Robert Lufkin What I discuss: Exosomes for regeneration: cartilage, bone, and joint repair ... 00:02:19 Exosomes vs. PRP and stem cells—key differences ... 00:05:20 Managing inflammation before regenerative treatments ... 00:06:09 Exosomes in neurology & anti-aging ... 00:07:01 Regulation, safety, and advances in exosome therapy ... 00:08:33 Mammogram controversy: risks, overdiagnosis, and dense breasts ... 00:10:00 Alternatives: QT scan benefits and radiation-free screening ... 00:15:21 Optimizing mitochondrial health—importance & methylene blue ... 00:18:28 Widespread mitochondrial dysfunction & modern disruptors ... 00:21:03 How methylene blue supports energy & cautions ... 00:23:17 Bone health: density vs. quality, collagen, and vibration plates ... 00:31:17 Mechanical input & gaps in traditional osteoporosis care ... 00:34:22 Lifestyle reversal of chronic disease ... 00:37:15 Medical system limitations & patient health agency ... 00:39:25 Fasting and metabolic health—power & nuance ... 00:48:06 Our Amazing Sponsors: Ultimate GI Repair by LVLUP Health - Whether you're struggling with digestive discomfort or want to strengthen your gut health, Ultimate GI Repair provides the comprehensive support your body needs to restore balance. The ingredients are unmatched! Visit https://lvluphealth.com/ and use code NAT at checkout for 20 % off. More from Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

I’m your host, Nathalie Niddam, and today I’m thrilled to bring you a truly fascinating conversation with Dr. Stephanie Canestraro—a chiropractor, functional medicine practitioner, and someone with an incredible personal story about overcoming chronic illness. Dr. Canestraro works with elite athletes, including NHL players, but her expertise comes from her own journey through mysterious health challenges that eventually led her to discover the vital role of the lymphatic system. What we discuss: Dr. Canestraro’s personal health journey and lymphatic issues ... 00:07:58 Explanation of the lymphatic system ... 00:10:33 Superficial vs. deep lymphatics and fascia’s role ... 00:15:20 Personal stories of lymphatic stagnation and deep lymph solutions ... 00:17:03 Why movement isn’t always enough for lymph flow ... 00:2447 Modern challenges: EMFs, toxins, fascia, and liver ... 00:25:00 Lymph, anxiety, and the vagus nerve ... 00:35:40 Tools and approaches for lymph support ... 00:39:22 Body-wide impact of fascia ... 00:43:47 Frequency medicine and resilience strategies ... 00:51:16 Our Amazing Sponsors: Bio-Shield by Young Goose - It’s a broad-spectrum serum that protects against UVA/UVB, infrared, AND high-energy visible (HEV) light—aka the stuff pouring out of your laptop right now. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you’re an existing customer. Troscriptions - Blue Cannatine - think of it as a small but mighty brain boost that melts in your mouth. A precise blend of methylene blue, caffeine, CBD, and microdosed nicotine gives me steady energy, focus, and mental clarity without the usual ups and downs. Try it for yourself at troscriptions.com and use code NAT10 for 10% off. Get in the zone and stay there. OraltidePro - A unique mouthwash that: Promotes growth of shrinking gums, Speeds healing of mouth & tongue, Prevents oral infections (such as gingivitis), Helps with enamel remineralization, Reduces bacteria growth and etching and Fills slots in damaged enamel. check out OraltidePro at profound-health.com and use code NAT15 for 15% off your first order. More from Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

In this episode, I’m thrilled to sit down with Dr. Robert Melillo, a clinical neuroscientist with nearly 40 years of experience decoding the mysteries of the brain and how our modern lifestyle—and especially technology—are changing it. If you’ve ever worried about what all that screen time means for your kids’ developing brains (or your own), this conversation is going to give you a whole new perspective. What we discuss: Left/right brain imbalance and modern tech’s impact ... 00:12:31 Gut health, peptides, and foundational health tips ... 00:05:37 Dr. Melillo’s journey, research, and clinical experience ... 00:08:04 Technology’s rapid evolution vs. brain adaptation ... 00:12:31 Making brain health more accessible ... 00:15:39 Biohacking brain interventions: risks and basics ... 00:17:34 ADHD, OCD, and the connectivity problem ... 00:20:14 How brain imbalances manifest and can be changed ... 00:23:45 Root causes: movement, milestones, and environment ... 00:39:09 Functional treatment: targeted, practical steps ... 00:47:25 Technology, lifestyle, and the left-brain epidemic ... 00:55:50 Correcting imbalances at any age ... 01:06:02 Dr. Melillo’s resources and how to learn more ... 01:14:38 Our Amazing Sponsors: CAROL Bike: With its cutting-edge, science-backed method, CAROL Bike can boost your VO2max by 12% in just 8 weeks—essentially rewinding your fitness clock by a decade. The folks at CAROL Bike are offering a 100-day FREE trial! Visit http://carolbike.pxf.io/Nat or use code NAT100 for a free 100-day trial. Ultimate GI Repair by LVLUP Health - Whether you're struggling with digestive discomfort or want to strengthen your gut health, Ultimate GI Repair provides the comprehensive support your body needs to restore balance. The ingredients are unmatched! Visit https://lvluphealth.com/ and use code NAT at checkout for 20 % off. Berkeley Life: Nitric oxide is key for blood flow, energy, brain clarity, and even healthy blood pressure. When you subscribe at BerkeleyLife.com/NAT, you’ll get a free tube of 50 nitric oxide test strips with your first delivery, so you can track how your body responds. Visit BerkeleyLife.com/NAT and click “Subscribe” to get started. More from Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

Today I’m joined by my friend and fellow biohacker, Dave Korsunsky, founder of Heads Up Health. In this episode, we take you on a journey through the evolution of biohacking—from the early days when continuous glucose monitors were a novelty and cryotherapy sounded like science fiction, all the way to the sophisticated, data-driven tools we have at our fingertips today. What we discuss: Dave’s journey: Heads Up Health and the rise of health data ... 00:08:18 Making sense of health metrics: Knowing if protocols work ... 00:10:06 GLP-1s: muscle loss risks, proper technique, and hydration ... 00:16:18 Clinical stories: HRV, autoimmune disease, and diabetes management ... 00:25:57 The foundational power of sleep, hydration, and micro-experiments ... 00:34:14 Core metrics: HRV, blood sugar, sleep, and their significance ... 00:40:46 The promise and impact of new longevity diagnostics ... 00:50:42 No-equipment longevity tests: grip, hang, balance, sit-to-stand ... 01:00:31 Aggregate your data and run micro-experiments ... 01:05:25 Our Amazing Sponsors: Bio-Shield by Young Goose - It’s a broad-spectrum serum that protects against UVA/UVB, infrared, AND high-energy visible (HEV) light—aka the stuff pouring out of your laptop right now. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you’re an existing customer. Troscriptions - Blue Cannatine - think of it as a small but mighty brain boost that melts in your mouth. A precise blend of methylene blue, caffeine, CBD, and microdosed nicotine gives me steady energy, focus, and mental clarity without the usual ups and downs. Try it for yourself at troscriptions.com and use code NAT10 for 10% off. Get in the zone and stay there. OraltidePro - A unique mouthwash that: Promotes growth of shrinking gums, Speeds healing of mouth & tongue, Prevents oral infections (such as gingivitis), Helps with enamel remineralization, Reduces bacteria growth and etching and Fills slots in damaged enamel. check out OraltidePro at profound-health.com and use code NAT15 for 15% off your first order. More from Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

Welcome back to the Longevity Podcast! I’m your host, Nathalie Niddam—a nutritionist, human potential and epigenetic coach, and devoted biohacker. Today, I’m tackling one of your most-requested topics: Thymosin Alpha 1, a peptide that keeps lighting up conversations in my communities. Resources from the episode: Thymosin alpha 1: A comprehensive review of the literature What we discuss: Overview of Thymosin alpha-1 ... 00:02:16 Medical uses, orphan drug status, and immune effects ... 00:03:53 Contraindications and vaccine adjuvant potential ... 00:05:01 Benefits in sepsis, infections, and elderly ... 00:07:40 Mechanisms of action and immune modulation ... 00:08:31 Antimicrobial properties and hospital study highlights ... 00:09:13 Support in aging, cancer, chemo, and mold toxicity ... 00:09:53 Cautions for autoimmune and sensitive individuals ... 00:13:04 Potential cancer therapy support and anti-inflammatory effects ... 00:14:48 Wound healing, safety, and administration ... 00:20:23 Risks, final cautions, and practitioner advice ... 00:23:15 App resource, newsletter, and wrap-up ... 00:25:24 Our Amazing Sponsors: Masszymes by BiOptimizers - is the most complete, most potent digestive enzyme with over 102% MORE PROTEASE than the nearest competitor. That’s crucial, because protein is the most complex macronutrient to break down. Try MassZymes at bioptimizers.com/bionat and enter the coupon code BIONAT to get 10% off your order. More from Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

Welcome back to the Longevity Podcast! In this episode, I have the pleasure of sitting down with James Strole, a beacon in the radical longevity space and the visionary founder behind People Unlimited and RAADfest. James shares the personal journey that led him into the world of life extension—shaped by a spiritually open-minded mother, a pivotal loss, and a lifelong desire to challenge the idea that aging is inevitable. Get 10% off your tickets to RAADfest using code: "niddam" What we discuss: James Strole’s personal journey to radical longevity ... 00:04:00 Spiritual roots and early inspiration ... 00:10:00 Transition from spiritual to scientific approaches ... 00:13:00 Launching RAADfest and the shift toward hard science ... 00:16:00 Evolution of the longevity movement over the decade ... 00:21:00 Access to longevity innovations and RAAD Clinics ... 00:22:00 Most exciting developments: gene therapy and age reversal ... 00:24:00 Daily longevity pillars: diet, movement, mindset ... 00:26:00 Mindset and embracing the possibility of immortality ... 00:35:00 Overcoming skepticism and “against nature” arguments ... 00:41:00 Societal implications of extreme longevity ... 00:44:00 Are we at the tipping point? The “era of immortality” ... 00:47:00 Advice for newcomers: join the conversation and community ... 00:50:00 Our Amazing Sponsors: NEW Timeline Gummies: Urolithin A supports muscle strength and cellular energy. It’s about improving how your body functions at the source. Mitopure is the only clinically proven Urolithin A, giving you six times more than you’d get from a glass of pomegranate juice. Visit Timeline.com/nat20 and use code nat20 for 20% off your purchase. Mitoblue by Wizard Sciences - Everything in the formula is there to help you think clearer, move better, and stay resilient—mentally and physically - Methylene Blue, NMN, PQQ, Apigenin and Ginseng Go to wizardsciences.com and look for MitoBlue. Use code NAT15 at checkout to get 15% off your purchase. Mimio: A supplement that gives you all the cellular, metabolic, and longevity benefits of a prolonged fast—even on the days when you’re eating normally. Visit mimiohealth.com/nat and use code NAT FOR 20% off your first single purchase or subscription order. More from Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

Welcome back to the Longevity Podcast! I’m so excited to share today’s episode with you, because it’s one that’s deeply personal and truly inspiring. I had the pleasure of sitting down with Dr. Tudor Marinescu, a remarkable physician I met during one of the Sedona retreats I co-host. Although he began his career as a trauma and orthopedic surgeon in Germany, Dr. Tudor’s path soon led him far beyond traditional medicine. Now, he’s known for his transformative work in osteopathy, neural therapy, and the exploration of how trauma—both physical and emotional—can shape our health and longevity. Find an amazing practitioner like Dr. Tudor near you: https://klinghardtinstitute.com/art-practitioners/ for A.R.T https://cranialacademy.org/find-a-physician/ for Osteopathy https://naant.org/by-any-word/ for Neural therapy https://www.doctortudor.com/ What we discuss: Dr. Tudor’s pivotal moments and holistic shift ... 00:08:23 Osteopathy principles and the body as a memory bank ... 00:14:30 How emotions, trauma, and fascia affect healing ... 00:18:58 History of mind-body separation in medicine ... 00:21:38 Integration of spiritual, emotional, and physical healing ... 00:26:11 Understanding fascia: structure, hydration, and movement ... 00:38:00 Neural therapy and procaine’s role in trauma release ... 00:54:08 Breaking trauma cycles: autonomic nervous system reset ... 00:59:54 Linking physical symptoms to emotional and spiritual health ... 01:09:38 Blending allopathic with holistic and ancestral medicine ... 01:20:46 How to find qualified holistic practitioners ... 01:26:39 Dr. Tudor’s contact info and Sedona retreat details ... 01:31:07 Final thoughts and disclaimer ... 01:33:53 Our Amazing Sponsors: Peptide Pro App: can help manage every part of your peptide protocol. From smart scheduling to real-time dose checklists, note taking, and easy calculations. Listeners receive 50% off for the first month. Visit www.peptidepro.app to download the app and use code NATHALIE50 to get started today. BEAM Minerals - are one of the most overlooked contributors to a healthy gut. They help feed and support your microbiome. Research shows that good gut bacteria rely on essential minerals like calcium, magnesium, zinc, iron, and phosphorus to thrive.. Head over to www.beamminerals.com and use code NAT20 for 20% off your first order and give your gut the simple support it deserves! Ultimate GI Repair by LVLUP Health - Whether you're struggling with digestive discomfort or want to strengthen your gut health, Ultimate GI Repair provides the comprehensive support your body needs to restore balance. Filled with key peptides for healing! Visit https://lvluphealth.com/ and use code NAT at checkout for 20 % off. More from Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

Welcome back to the Longevity Podcast! I’m so excited for today’s episode, where I sit down with Chris Rhodes—nutritional biochemist, fasting researcher, and CEO of Mimio Health—to dive deep into one of the most fascinating emerging topics in longevity science: fasting mimetics. If you’ve ever wanted to get the regenerative, anti-inflammatory, and health-boosting effects of fasting, but struggled to actually fast for 36 hours or more (trust me, I get it!), this conversation is for you. Listeners of this podcast can visit mimiohealth.com/nat and use code NAT FOR 20% off your first single purchase or subscription order. What we discuss: Meet Chris Rhodes and his biomimetic research journey ... 00:05:18 Unlocking fasting benefits without prolonged fasting ... 00:09:10 Supplements vs. pharmaceuticals for longevity ... 00:10:53 Fasting protocols, timing, and metabolic switching ... 00:15:23 Risks of fasting, evolutionary adaptation, and muscle/bone loss ... 00:18:34 Ketones, brain energy, and cognitive adaptation ... 00:22:48 How fasting activates longevity and repair pathways ... 00:26:23 Key cellular pathways: AMPK, mTOR, NAD, sirtuins ... 00:28:04 Mimio research: discovering and testing fasting metabolites ... 00:33:35 The four main fasting mimetic molecules explained ... 00:42:04 Practical benefits: who should use fasting mimetics & safety ... 00:59:00 Mimio in use: hunger control, GLP-1 support, and older adults ... 01:03:37 Our Amazing Sponsors: Qualia NAD+ - This vital molecule powers cellular energy, supports DNA health, aids detox, and helps keep your body remain youthful. Visit qualialife.com/nathalie to try Qualia NAD+, backed by a 100-day money-back guarantee, and use promo code NATHALIE for 15% off! OraltidePro - A unique mouthwash that: Promotes growth of shrinking gums, Speeds healing of mouth & tongue, Prevents oral infections (such as gingivitis), Helps with enamel remineralization, Reduces bacteria growth and etching and Fills slots in damaged enamel. Check out OraltidePro at profound-health.com and use code NAT15 for 15% off your first order. Bio-Shield by Young Goose - A broad-spectrum serum that protects against UVA/UVB, infrared, AND high-energy visible (HEV) light. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you’re an existing customer. More from Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

Welcome back to the Longevity Podcast! I’m your host, Nathalie Niddam—nutritionist, human potential and epigenetic coach, and I’m excited to share another solo episode with you. Today, I’m diving into a topic that really resonated with my community on Instagram: five essential habits I wish everyone in their 40s (and honestly, any age!) knew to set themselves up for better health and longevity—without spending a dime. Resources from the episode: • Grounding – The universal anti-inflammatory remedy • Associations between bedtime eating or drinking, sleep duration and wake after sleep onset: findings from the American time use survey • Meal Timing and Anthropometric and Metabolic Outcomes • Meal Timing, Aging, and Metabolic Health • Obstructive sleep apnea and neurodegenerative diseases: A bidirectional relation • Investigation on the Effect of Oral Breathing on Cognitive Activity Using Functional Brain Imaging What we discuss: Digestive bitters before meals: benefits and how to use ... 00:02:10 Digestive bitters: impact on digestion, absorption, and immune system ... 00:04:01 Digestive bitters: sources, supplements, and usage tips ... 00:08:17 Training your glymphatic system for brain health ... 00:09:12 Tips to support glymphatic drainage: sleep, exercise, hydration, nutrition, sleep position ... 00:10:19 Grounding: definition, science, and health impact ... 00:13:39 How to ground in urban environments; grounding sheets and tools ... 00:17:08 Eating dinner three hours before bed: why and how ... 00:19:02 Early dinner vs. skipping breakfast for metabolic health ... 00:21:36 Circadian rhythm alignment tips and jet lag hacks ... 00:24:05 Nasal breathing vs. mouth breathing: importance and intro to solutions ... 00:24:36 Mouth breathing risks, sleep apnea, and cognitive implications ... 00:26:52 Practical tools and professionals for correcting mouth breathing ... 00:29:12 Summary of the five key longevity tips ... 00:31:59 Our Amazing Sponsors: MitoBlue by Wizard Sciences - Everything in the formula is there to help you think clearer, move better, and stay resilient—mentally and physically—Methylene Blue, NMN, PQQ, Apigenin and Ginseng. Go to wizardsciences.com and look for MitoBlue. Use code NAT15 at checkout to get 15% off your purchase. More from Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

I had the chance to sit down with one of the original pioneers of the biohacking movement: Dave Asprey. You probably know Dave as the founder of Bulletproof, the mastermind behind putting butter in coffee, and the creator of Upgrade Labs and the Biohacking Conference. He’s also a four-time New York Times bestselling author. What we discuss: Biohacking’s relationship with longevity and functional medicine ... 00:10:47 The importance of energy, joy, and personalization in longevity ... 00:14:28 Democratizing lab tests and health optimization with AXO Health ... 00:24:00 Most common health imbalances: thyroid, hormones, minerals ... 00:33:25 Danger Coffee and foundational supplement protocols ... 00:39:43 Pitfalls of oversimplification in health and biohacking ... 00:45:52 Making advanced therapies and tech more accessible ... 00:53:23 Ethical and societal considerations in radical longevity ... 01:07:00 Where to find Dave Asprey and closing remarks ... 01:11:58 Our Amazing Sponsors: Mitolux NEW Second Generation - This second-generation red and near-infrared light therapy panel hits all the marks. Two new wavelengths—810nm and 940nm—target brain performance, deep muscle recovery, and circulation. I use GAMA mode when I want to lock in focus, and Fireplace 2 when I want to wind down. Get a Mitolux BTS2 Sunlamp for 10% off at https://mitolux.com/NAT10, NAT10 will be automatically applied at checkout. Mimio: A supplement that gives you all the cellular, metabolic, and longevity benefits of a prolonged fast—even on the days when you’re eating normally. Visit mimiohealth.com/nat and use code NAT FOR 20% off your first single purchase or subscription order. NEW Timeline Gummies: Urolithin A supports muscle strength and cellular energy. It’s about improving how your body functions at the source. Mitopure is the only clinically proven Urolithin A, giving you six times more than you’d get from a glass of pomegranate juice. Visit shop.timeline.com/NAT10 and use code NAT10 for 10% off. More from Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

I’m joined today by Oliver Amdrup-Chamby, the co-founder of Puori and a true trailblazer in supplement transparency and quality. We break down everything you need to know to become a more informed consumer, from how to avoid hidden contaminants like heavy metals, pesticides, and microplastics, to why oxidation in fish oil is such a big deal, and the real story behind protein powders—especially the plant-based ones. Listeners of this podcast get 20% off of Puori protein, a one-time purchase or if you choose the already discounted subscription, you get almost a third off the price! Visit Puori.com/NAT and use my promo code NAT. What we discuss: Supplements: contamination, purity, and Danish regulation ... 00:08:46 Fish oil: contaminants, microplastics, and oxidation ... 00:12:37 Fish oil quality: what to look for ... 00:15:19 Protein needs, trends, and bioavailability ... 00:24:08 Whey protein vs. plant protein ... 00:27:30 Making protein accessible for families ... 00:31:56 Heavy metals in protein powders ... 00:37:04 Sourcing and batch-level testing ... 00:41:19 Flavorings, sweeteners, and ingredient transparency ... 00:52:10 Tips for selecting clean protein and fish oil ... 01:07:36 Encouraging transparency and consumer advocacy ... 01:11:14 Our Amazing Sponsors: Profound Health - - Nature’s Marvels have been making bioregulators for over a decade, working directly with Prof. Khavinson, the pioneer of Bioregulator science! They’re manufactured in the UK. They’re GMP and HACCP certified and FDA-compliant. Whatever your health needs, there’s a bioregulator for you. Head to profound-health.com and use code NAT15 for 15% off your first order. CAROL Bike - With its cutting-edge, science-backed method, CAROL Bike can boost your VO2max by 12% in just 8 weeks—essentially rewinding your fitness clock by a decade. The folks at CAROL Bike are offering a 100-day FREE trial! Visit http://carolbike.pxf.io/Nat or use code NAT100 for a free 100-day trial. Quantum Upgrade - Imagine plugging yourself into a limitless power source. It’s been rigorously tested and shown to improve blood flow, reduce stress, and even boost cellular energy by up to 29%. Try it today at quantumupgrade.io/NAT and start running life, instead of life running you. Use my code NAT15 to get a 15-day free trial on the All-in-One Frequency Bundle. Good through June 1st, 2025 Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

Today, I’m joined by Teo Soleymani, MD—a double board-certified dermatologist, fellowship-trained Mohs and facial reconstructive surgeon, and an expert in all things skin cancer—plus, he’s as entertaining as he is knowledgeable. If you’ve ever wondered whether you should slather on sunscreen religiously, or if embracing more sunlight is actually good for you, we’re here to offer the clarity and nuance that’s so often missing from the conversation. Listeners of this podcast can receive 15% off of SunPowder when you go to sunpowder.co/discount/NAT15 (it’s .co not .com or else you won’t find it). What we discuss: Sun exposure: fear vs. benefits debate ... 00:06:38 Genetics vs. sun in driving skin cancer risk ... 00:09:04 Types of skin cancer explained ... 00:10:38 HPV, environmental toxins, and non-UV causes ... 00:22:35 Burning vs. safe sun—practical advice ... 00:21:24 Sunscreen: mineral vs. chemical, what matters ... 00:36:01 Problems with spray sunscreens ... 00:40:45 Melanin, UV damage, and skin aging ... 00:13:40 Melasma: hormones and stubborn pigmentation ... 00:47:19 Estrogen, collagen, and topical supplements ... 00:49:18 Astaxanthin and polypodium—internal sun protection ... 00:56:01 Nicotinamide: strong evidence for cancer prevention ... 01:04:11 Sunpowder supplement: trials and benefits ... 01:07:43 Laser resurfacing and reduced cancer risk ... 01:12:33 Genetics, immune health, and testing limits ... 01:15:31 Where to find Sunpowder + connect with Teo ... 01:18:53 Our Amazing Sponsors: LVLUP - Neuro Re-Generate the world's first liposomal triple peptide formula, designed to support mental clarity, focus, and overall brain health. Visit www.lvluphealth.com and use code NAT for 20% off your order. Qualia - Senolytic - Clinically tested formula with 9 plant-based, vegan ingredients designed to help your body clear out zombie cells—so you can feel younger, faster. Visit qualialife.com/nathalie and use promo code NATHALIE to save 15% Young Goose L.A.D.R. Serum - Powered by light-activated DNA repair enzymes, NAD+, and collagen peptides, it reverses damage while you go about your life. Sunlight? Red light therapy? It all helps this serum work smarter, not harder. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you’re an existing customer. Future-proof your face. More from Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group More from Teo Soleymani: Website: www.californiadermatology.com and https://sunpowder.co/discount/NAT15 Instagram: @teosoleymanimd Instagram: @drinksunpowder

In this special solo episode, it’s just me, Nathalie Niddam—nutritionist, human potential and epigenetic coach—returning to my roots and diving deep into the world of peptides. Today, I’m shining a spotlight on KPV, a fascinating and often overlooked peptide with powerful anti-inflammatory, antimicrobial, and healing properties. What We Discuss: What are peptides? Clearing up misconceptions ... 00:01:00 KPV explained: structure and origins ... 00:03:00 How KPV works (anti-inflammatory mechanisms) ... 00:05:00 Comparison to Melanotan and tanning ... 00:08:00 KPV benefits: gut, antimicrobial, healing, immune modulation ... 00:09:00 KPV for gut and skin health ... 00:14:00 Neuroprotection and research potential ... 00:18:00 Administration methods: oral, topical, injectable ... 00:19:00 Safety profile and side effects ... 00:22:00 Tracking protocols and the Peptide Pro app ... 00:24:00 Recap and concluding remarks ... 00:30:00 Our Amazing Sponsor: BiOptimizers - MassZymes is the most complete, most potent digestive enzyme with over 102% MORE PROTEASE than the nearest competitor. That’s crucial because protein is the most complex macronutrient to break down. Try MassZymes at bioptimizers.com/bionat and enter the coupon code BIONAT to get 10% off your order. More From Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

Today, I’m joined by Cynthia Thurlow, a remarkable nurse practitioner, podcast host, and true hormone whisperer who is on a mission to help women thrive through perimenopause and beyond. What We Discuss: Perimenopause, menopause, and longevity connection ... 00:06:09 Hormone misunderstandings and HRT discussion ... 00:07:34 Cynthia’s clinical experience and women's health ... 00:07:53 Recognizing hormonal imbalances and PCOS in young women ... 00:12:09 Autoimmunity risks and thyroid issues ... 00:19:55 Lifestyle factors: aging, processed food, and alcohol ... 00:24:02 Fasting, digestive rest, and metabolic flexibility ... 00:35:02 Practical fasting tips for different age groups ... 00:36:38 Diet flexibility and protein-forward meals ... 00:41:26 Meal timing, circadian rhythm, and satiety ... 00:56:04 Muscle loss, strength training, and optimal protein ... 01:00:36 Gut microbiome recovery and dietary diversity ... 01:06:15 Creatine: benefits, dosing, and sourcing ... 01:08:36 Where to find Cynthia and her products ... 01:15:30 Thank You To Our Sponsors: Peptide Pro App: can help manage every part of your peptide protocol. From smart scheduling to real-time dose checklists, note taking, and easy calculations. Listeners receive 50% off for the first month. Visit www.peptidepro.app to download the app and use code NATHALIE50 to get started today. BEAM - These minerals come from humate, a natural substance formed over millions of years as freshwater plants broke down and deposited their nutrients into the soil. Over time, those minerals concentrated into this black, crystalline material that’s now one of the most mineral-dense substances on earth. That’s what’s going into your body—and your cells absorb it within minutes. Visit https://www.beamminerals.com/NAT20 and use code NAT20 for 20% off. Wizard Sciences - Mitoblue - Everything in the formula is there to help you think clearer, move better, and stay resilient—mentally and physically - Methylene Blue, NMN, PQQ, Apigenin and Ginseng. Go to wizardsciences.com and look for MitoBlue. Use code NAT15 at checkout to get 15% off your purchase. Learn more from Cynthia Thurlow: Website Twitter Instagram Facebook LinkedIn Youtube Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

Today, I’m joined by Ulrich Dempfle, the innovative mind behind the CAROL Bike. Ulrich’s journey is fascinating—he started as a mechanical engineer in Europe, became a pioneer in hospital AI systems, and is now laser-focused on bringing cutting-edge fitness tech to regular people, like you and me. What we discuss: Zone 2 training: hype, benefits, and limitations ... 00:08:00 VO2 max: definition and importance for longevity ... 00:10:00 The impracticality and issues with Zone 2 for most people ... 00:15:00 Downsides of long-duration steady-state cardio ... 00:18:00 Why strength and mobility also matter ... 00:17:00 Carol Bike and REHIT: efficient fitness for longevity ... 00:31:00 REHIT’s proven VO2 max and metabolic improvements ... 00:36:00 Personalization and ease-of-use with Carol Bike ... 00:49:00 Carol Bike’s versatility: multiple workouts and app integrations ... 00:57:00 Who Carol Bike is for and safety notes ... 01:10:00 Carol Bike trial info, research, and closing ... 01:12:00 Our Amazing Sponsors: Troscriptions - Blue Cannatine - think of it as a small but mighty brain boost that melts in your mouth. A precise blend of methylene blue, caffeine, CBD, and microdosed nicotine gives me steady energy, focus, and mental clarity without the usual ups and downs. Try it for yourself at troscriptions.com and use code NAT10 for 10% off. Get in the zone and stay there. Timeline: Mitopure®️ is a breakthrough supplement that promotes cellular renewal. It contains Urolithin A, which helps your body clear out damaged mitochondria and create new, efficient ones—giving you more sustainable energy. Timeline is offering 10% off your order of Mitopure now. Go to timeline.com/NAT10. Profound Health - Nature’s Marvels have been making bioregulators for over a decade, working directly with Prof. Khavinson, the pioneer of Bioregulator science! They’re manufactured in the UK. They’re GMP and HACCP certified and FDA-compliant. Whatever your health needs, there’s a bioregulator for you. Head to profound-health.com and use code NAT15 for 15% off your first order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

Today, I sit down with Dr. Christy Sutton, author of The Iron Curse and an expert whose personal journey through her husband’s long and confusing health saga opened her eyes to the often-missed danger of hereditary hemochromatosis. What we discuss: Meet Dr. Christy Sutton and Her Personal Story ... 00:06:00 Hemochromatosis: Genetics, Diagnosis, and Mistreatment ... 00:11:00 Multi-Organ Impact of Iron Overload ... 00:33:00 Childhood Hemochromatosis and Clinical Blind Spots ... 00:37:00 A five-year-old’s story reveals difficulties in pediatric diagnosis and innovative, non-blood-removal strategies. Symptoms, Infections, and Iron ... 00:47:00 Systemic issues like joint pain, anxiety, dementia, and heightened risk of deadly infections. Managing and Lowering Iron Levels ... 01:01:00 Genetic Roots: Red Hair, Irish Heritage, and Family Risk ... 01:09:00 Key Takeaways and Resources ... 01:17:00 Screening recommendations, where to find Dr. Sutton’s work, and closing comments for listeners. Our Amazing Sponsors: Puori: If you want clean, high-quality protein without the mystery contaminants, check out Puori PW1. Receive 20% off a one-time purchase or if you choose the already discounted subscription, you get almost a third off the price! Visit Puori.com/NAT and use my promo code NAT. Young Goose L.A.D.R. Serum - Powered by light-activated DNA repair enzymes, NAD+, and collagen peptides, it reverses damage while you go about your life. Sunlight? Red light therapy? It all helps this serum work smarter, not harder. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you’re an existing customer. Future-proof your face. Fresh-Pressed Olive Oil Club: As an introduction to his Fresh-Pressed Olive Oil Club, T. J. is willing to send you a full-size $39 bottle of one of the world’s finest artisanal olive oils — fresh from the new harvest—for just $1 to help him cover shipping. No commitment to buy anything, now or ever. Go to GetFreshLongevity.com for a free bottle and pay just $1. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

Today I’m excited to bring you a conversation with my friend and special guest, Ben Azadi—founder of Keto Kamp and author of Metabolic Freedom. In this episode, Ben and I take on some of the most stubborn myths around metabolism and weight loss, especially the widely held belief that “calories in, calories out” is the key to health. What we discuss: Why calorie-counting fails and metabolic flexibility matters ... 00:03:39 Biggest Loser study and gut health ... 00:11:14 Processed foods, seed oils, and saturated fats explained ... 00:17:07 Keto diet evolution, mistakes, and carb cycling ... 00:26:48 Dr. Pompa’s metabolic variation protocols ... 00:37:41 Intermittent fasting pitfalls and how to fast smart ... 00:41:54 Meal frequency and metabolism myths ... 00:45:59 Muscle mass as metabolic health foundation ... 00:47:00 Who benefits—and who doesn’t—from keto ... 00:50:12 Hidden blood sugar spikes from “health foods” ... 00:53:23 Ben’s top tip: Vitamin G (gratitude) ... 00:55:15 Why weight regain happens after keto—self-image ... 00:58:27 Gender differences in keto response ... 01:01:50 Where to find Ben Azadi and Metabolic Freedom ... 01:03:37 Our Amazing Sponsors: Quantum Upgrade - Imagine plugging yourself into a limitless power source. It’s been rigorously tested and shown to improve blood flow, reduce stress, and even boost cellular energy by up to 29%.Try it today at quantumupgrade.io/NAT and start running life, instead of life running you. Use my code NAT15 to get a 15-day free trial on the All-in-One Frequency Bundle. Good through June 1st, 2025 Peptide Pro App: can help manage every part of your peptide protocol. From smart scheduling to real-time dose checklists, note taking, and easy calculations. Listeners receive 50% off for the first month. Visit www.peptidepro.app to download the app and use code NATHALIE50 to get started today. BiOptimizers - MassZymes is the most complete, most potent digestive enzyme with over 102% MORE PROTEASE than the nearest competitor. That’s crucial, because protein is the most complex macronutrient to break down. Try MassZymes at bioptimizers.com/bionat and enter the coupon code BIONAT to get 10% off your order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

If you’ve been anywhere near health optimization circles, you already know Ben Greenfield as a NYT bestselling author, former Ironman triathlete, coach, one of the OGs of biohacking. Today, he’s my guest on the Longevity podcast. What we discuss: Ben’s new home, cold exposure, and microdosing cryotherapy ... 00:06 Writing, updating, and revising “Boundless” ... 00:09 Key updates: Self-quantification, longevity, new detox protocols ... 00:12 High-tech blood filtration and its impact ... 00:15 Daily detox strategies: Lymphatic movement, sauna, exercise ... 00:17 Ben’s evolution: From strict keto to Mediterranean-style eating ... 00:21 Genetics, ancestry, and personalized nutrition lessons ... 00:23 Impact of endurance training, hormone and gut issues, recovery via flexible dieting ... 00:27 Addressing high coronary plaque: Statins, PCSK9 inhibitors, supplementation ... 00:35 Tracking heart health non-invasively (CIMT) ... 00:38 Thoughtful, limited use of pharmaceuticals for health ... 00:44 Peptides: Orals, protocols, favorites (BPC-157, TA1, etc.) ... 00:47 GLP-1 agonists: Powerful but require careful dosing ... 00:51 Biohacks gone wrong: Dosing mishaps and psychedelic stories ... 00:55 Ben’s three core tips: Family time, naps, and prayer ... 00:58 Our Amazing Sponsors: Wizard Sciences - Mitoblue Everything in the formula is there to help you think clearer, move better, and stay resilient mentally and physically - Methylene Blue, NMN, PQQ, Apigenin and Ginseng. Go to wizardsciences.com and look for MitoBlue. Use code NAT15 at checkout to get 15% off your purchase. Mitolux NEW Second Generation - This second-generation red and near-infrared light therapy panel hits all the marks. Two new wavelengths—810nm and 940nm—target brain performance, deep muscle recovery, and circulation. I use GAMA mode when I want to lock in focus, and Fireplace 2 when I want to wind down. Get a Mitolux BTS2 Sunlamp for 10% off at https://mitolux.com/NAT10, NAT10 will be automatically applied at checkout. LVLUP - Neuro Re-Generate the world's first liposomal triple peptide formula, designed to support mental clarity, focus, and overall brain health. Visit www.lvluphealth.com and use code NAT for 10% off your order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

In this episode, I dive deep into the transformative world of regenerative medicine with Dr. Ed Park—a leader who has spent nearly two decades pushing the boundaries of aging and healing. Curious about exosomes and how these tiny biological messengers are redefining our ability to recover from injury, illness, and even chronic conditions? You’ll love this conversation. What we discuss: Why exosomes? Origins, discovery, and benefits of stem cells ... 00:03:00 How exosomes communicate and trigger healing ... 00:06:00 Exosomes for neurological repair and brain injuries ... 00:10:00 Exosome delivery: IV, targeting, and blood-brain barrier ... 00:12:00 Exosomes in musculoskeletal injuries and healing rates ... 00:18:00 Patient selection, expectations, and placebo effects ... 00:23:00 Exosomes for immune system support and aging ... 00:30:00 Lifestyle pillars alongside regenerative medicine ... 00:32:00 Exosomes in cardiac and nerve repair ... 00:34:00 Provider training, resources, and Dr. Park’s practice ... 00:43:00 Closing remarks and medical disclaimer ... 00:45:00 Our Amazing Sponsors: Timeline: Mitopure: is a breakthrough supplement that promotes cellular renewal. It contains Urolithin A, which helps your body clear out damaged mitochondria and create new, efficient ones—giving you more sustainable energy. Timeline is offering 10% off your order of Mitopure now. Go to timeline.com/NAT10. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group