The Dr. Hyman Show

Dwayne “The Rock” Johnson isn’t just a global icon—he’s a father of three and a passionate advocate for taking control of your health. On this episode of The Dr. Hyman Show, I sit down with Dwayne to talk about what it really means to own your health. From advanced labs and AI tools to the power of functional medicine, he shares how root-cause approaches have helped him stay ahead of health risks, stay grounded through stress, and show up for the people who matter most.We discuss:• The overlooked lab tests that could change the way you manage your health• How gut imbalances can quietly impact your mood, memory, and metabolism• Simple habits that anchor your health—especially when life gets hectic• How prioritizing health helped Dwayne show up better as a father—and why that lesson applies to all of us This lively conversation covers a lot of ground, with insights on fatherhood, aging, and purpose—it’s a powerful reminder that real strength starts from within. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive

Autoimmune disease is explored as a complex and rising health challenge driven largely by lifestyle and environmental factors rather than genetics alone. Conventional treatments often rely on immune-suppressing medications that manage symptoms but fail to address underlying causes like gut dysfunction, chronic infections, toxins, and stress. A functional medicine approach instead emphasizes identifying and treating these root causes—such as gluten sensitivity, dysbiosis, and nutrient deficiencies—through personalized diagnostics and anti-inflammatory diets. Case studies illustrate dramatic improvements in patients' symptoms and lab results when switching from conventional to root-cause-based care. Ultimately, this integrative model empowers individuals to reclaim health by addressing what triggers immune system dysfunction in the first place. In this episode, I discuss, along with Dr. Sunjya Schweig, Dr. Cindy Geyer, and Dr. Todd LePine the root cause approach to healing autoimmune conditions. Dr. Sunjya K. Schweig is dedicated to advancing data-driven approaches to prevent and reverse chronic illness. He is the Founder and President of the California Center for Functional Medicine (CCFM), where he and his team deliver personalized, precision care using innovative technology and a comprehensive team-based model. Since 2016, CCFM has also supported first responders through specialized wellness programs. In 2021, Dr. Schweig launched the Functional Medicine Research and Technology Center to further research, education, and innovation in chronic disease prevention. A graduate of UC Berkeley, he earned his MD from UC Irvine and completed his residency at UCSF Santa Rosa. He is board-certified in family practice and integrative and holistic medicine. Dr. Cindy Geyer received her bachelor of science and her doctor of medicine degrees, with honors, from the Ohio State University. She completed residency in internal medicine at Strong Memorial Hospital in Rochester, N.Y. and is triple board certified in internal medicine, integrative medicine and lifestyle medicine. Dr. Todd LePine graduated from Dartmouth Medical School and is Board Certified in Internal Medicine, specializing in Integrative Functional Medicine. He is an Institute for Functional Medicine Certified Practitioner. Prior to joining The UltraWellness Center, he worked as a physician at Canyon Ranch in Lenox, MA, for 10 years. Dr. LePine’s focus at The UltraWellness Center is to help his patients achieve optimal health and vitality by restoring the natural balance to both the mind and the body. His areas of interest include optimal aging, bio-detoxification, functional gastrointestinal health, systemic inflammation, autoimmune disorders, and the neurobiology of mood and cognitive disorders. Dr. LePine enjoys skiing, kayaking, hiking, camping, and golfing in the beautiful Berkshires, and is a fitness enthusiast. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: Healing Autoimmune Disease Using A Functional Medicine ApproachIs An Autoimmune Condition Driving Your Raynaud's Syndrome?What Really Causes Autoimmune Disease

This special bonus episode features Dr. George Papanicolaou from the UltraWellness Center, diving into how functional medicine approaches ADHD — and why the root cause is rarely just in the brain. In this conversation, Dr. Papanicolaou shares the story of a young woman struggling with ADHD symptoms that conventional medicine failed to resolve. Through a deeper investigation into gut health, nutrient deficiencies, mitochondrial dysfunction, and even genetics, Dr. Papanicolaou explains how addressing the body’s imbalances can dramatically improve focus, energy, and emotional regulation. You’ll learn: • Why ADHD is being diagnosed more than ever—and what you might be missing • How your gut health affects your brain, inflammation, and attention • Why nutrients like omega-3s, vitamin D, and magnesium are essential for cognitive health • How your genes and lifestyle work together to shape your brain health • What you can do—without medication—to support mental clarity and better focusThis is part of a limited bonus series spotlighting the work of the UltraWellness Center team, with new episodes dropping monthly on select Fridays. To learn more about the UltraWellness Center or inquire about becoming a patient, visit: https://ultrawellnesscenter.com

Dr. Jeff Bland has been a guiding force in my life—and in the world of Functional Medicine. For decades, his work has helped shift medicine away from naming and blaming disease, toward truly understanding and addressing its root causes. In this episode of The Dr. Hyman Show, Jeff and I continue our conversation about how to turn the tide on chronic disease—starting with the immune system. We discuss: • How aging quietly weakens your immune system—and why you don’t have to accept it • How phytochemicals act as gene regulators—not just antioxidants • Why your diet might be accelerating immune dysfunction (and how to fix it) • Why Himalayan Tartary Buckwheat may be the most powerful food you’re not eating (yet) • What it means to rejuvenate your immune system—and how to start doing it today This conversation is personal for both of us—and a powerful reminder that when we care for the body, it has an incredible capacity to heal. View Show Notes From This EpisodeGet Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Healthhttps://drhyman.com/pages/10-day-detoxJoin the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive This episode is brought to you by BON CHARGE, Big Bold Health, Pique, PerfectAmino and AirDoctor. Go to boncharge.com and use code DRMARK to save 15% on your PEMF mat today. Try Omega-3 Rejuvenate®, visit bigboldhealth.com and use code DRMARK25 at checkout for 25% discount. Head to piquelife.com/hyman to get 20% off + a free beaker and frother today. Get pure essential amino acids today. Go to bodyhealth.com and use HYMAN20 to get 20% off your first order. Get cleaner air. Right now, you can get up to $300 off at airdoctorpro.com/drhyman.

Many chronic health conditions—such as IBS, asthma, and autoimmune disorders—can be traced back to imbalances in the gut. Disruptions to the microbiome caused by antibiotics, poor diet, food sensitivities, and environmental exposures can lead to inflammation, malabsorption, and increased intestinal permeability (leaky gut). Addressing gut health through a structured Functional Medicine approach called the 5R’s of gut repair—removing harmful triggers, replacing missing digestive factors, reinoculating with beneficial bacteria, repairing the gut lining, and rebalancing lifestyle factors—can restore balance and improve systemic health. In this episode, I discuss, along with Dr. Elizabeth Boham and Raja Dhir, the Functional Medicine approach to healing the gut and why the gut is at the center of imbalances in the body, including many health conditions. Dr. Elizabeth Boham is Board Certified in Family Medicine from Albany Medical School, and she is an Institute for Functional Medicine Certified Practitioner and the Medical Director of The UltraWellness Center. Dr. Boham lectures on a variety of topics, including Women’s Health and Breast Cancer Prevention, insulin resistance, heart health, weight control and allergies. She is on the faculty for the Institute for Functional Medicine. Raja Dhir is the co-founder and co-CEO of Seed Health, a microbiome science company developing innovative probiotics and living medicines to advance human and planetary health. He specializes in translating cutting-edge microbial research into impactful products and leads Seed Health’s academic collaborations with institutions such as MIT, Harvard, Stanford, Caltech, and the NIH. Raja co-chairs Seed’s Scientific Board alongside Dr. Jacques Ravel, guiding research across microbiology, immunology, genetics, and ecology. He also directs LUCA Biologics, a company focused on the vaginal microbiome and women's health, and oversees SeedLabs, which drives environmental initiatives. Through this work, Raja plays a key role in accelerating microbiome-based solutions from discovery to market. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: What Is Leaky Gut And How Can You Treat It?How to Select a Probiotic and the Future of the MicrobiomeHow To Do The 10-Day Detox

Dr. Jeff Bland has been called the father of Functional Medicine—and for good reason. His groundbreaking work helped shift our understanding of chronic disease and inspired a generation of doctors to look beyond symptoms and toward root causes. On this episode of The Dr. Hyman Show, I sit down with Jeff to talk about what he’s learned from more than 50 years of studying the science of health, aging, and disease prevention. We explore: • Why your biology is not predetermined by your genes—and how to unlock your full potential • What Jeff’s own health journey reveals about inflammation, biomarkers, and aging well • How what you eat can shape everything from inflammation to longevity • Long-term disease risk is shaped by what surrounds you—and how your body responds Tune in for an insightful conversation with one of my greatest mentors—and discover how science, curiosity, and personal agency can help you live a longer, healthier life. View Show Notes From This EpisodeGet Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcastSign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcastJoin the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detoxJoin the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive This episode is brought to you by Seed, BON CHARGE, Timeline, Paleovalley, and AirDoctor. Visit seed.com/hyman and use code 25HYMAN for 25% off your first month of Seed's DS-01® Daily Synbiotic. Go to boncharge.com and use code DRMARK to save 15% on your PEMF mat today. Support essential mitochondrial health and save 10% on Mitopure. Visit timeline.com/drhyman to get 10% off today. Get nutrient-dense, whole foods. Head to paleovalley.com/hyman for 15% off your first purchase. Get cleaner air. Right now, you can get up to $300 off at airdoctorpro.com/drhyman.

Skin issues like acne, eczema, and rosacea are deeply connected to internal imbalances, especially those originating in the gut. It is important to explore diet—particularly sugar, refined carbs, and dairy—because it can drive inflammation, insulin resistance, and hormonal disruption, all of which contribute to poor skin health. Topical treatments and antibiotics may provide short-term relief, but they often disrupt the skin and gut microbiome, worsening conditions over time. A Functional Medicine approach focuses on restoring gut balance, identifying food sensitivities, and supporting detoxification pathways with nutrient-dense foods, supplements, and lifestyle practices. Addressing the root causes not only improves skin but also promotes systemic healing and resilience. In this episode, I speak with three of our doctors at The UltraWellness Center—Dr. Elizabeth Boham, Dr. Cindy Geyer, and Dr. Todd LePine—about why, when it comes to skin care, we need to look inside the body first. Dr. Elizabeth Boham is Board Certified in Family Medicine from Albany Medical School, and she is an Institute for Functional Medicine Certified Practitioner and the Medical Director of The UltraWellness Center. Dr. Boham lectures on a variety of topics, including Women’s Health and Breast Cancer Prevention, insulin resistance, heart health, weight control and allergies. She is on the faculty for the Institute for Functional Medicine. Dr. Cindy Geyer received her bachelor of science and her doctor of medicine degrees, with honors, from the Ohio State University. She completed residency in internal medicine at Strong Memorial Hospital in Rochester, N.Y. and is triple board certified in internal medicine, integrative medicine and lifestyle medicine. Dr. Todd LePine graduated from Dartmouth Medical School and is Board Certified in Internal Medicine, specializing in Integrative Functional Medicine. He is an Institute for Functional Medicine Certified Practitioner. Prior to joining The UltraWellness Center, he worked as a physician at Canyon Ranch in Lenox, MA, for 10 years. Dr. LePine’s focus at The UltraWellness Center is to help his patients achieve optimal health and vitality by restoring the natural balance to both the mind and the body. His areas of interest include optimal aging, bio-detoxification, functional gastrointestinal health, systemic inflammation, autoimmune disorders, and the neurobiology of mood and cognitive disorders. Dr. LePine enjoys skiing, kayaking, hiking, camping, and golfing in the beautiful Berkshires, and is a fitness enthusiast. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: Treating Acne From The Inside OutChoosing Skin Care Products that Won’t Make You SickTreating Adult Acne & Rosacea From The Inside Out

Dr. Joel Warsh was trained in conventional pediatrics—but he quickly realized that vaccine conversations often overlook what matters most to you and your child’s unique health needs. On this episode of The Dr. Hyman Show, discover how Dr. Warsh blends medical research with real patient experience to offer an honest, balanced conversation about vaccines. Together, we share a practical discussion—exploring what we know and what we don’t—to empower you to make informed decisions. We explore: • How you can better understand vaccine risks and benefits to protect your child wisely • What questions to ask your pediatrician to ensure your concerns are heard • Ways you can strengthen your child’s immune system naturally before and after vaccination • Why focusing on prevention and root health supports your child’s long-term wellness Tune in for a grounded, thoughtful look at a complex topic—one that respects your questions, your values, and your role as a parent. View Show Notes From This EpisodeGet Free Weekly Health Tips from Dr. Hymanhttps://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcastSign Up for Dr. Hyman’s Weekly Longevity Journalhttps://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcastJoin the 10-Day Detox to Reset Your Healthhttps://drhyman.com/pages/10-day-detoxJoin the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive This episode is brought to you by Fatty15, PerfectAmino,Big Bold Health, LMNT, Pique Head to fatty15.com/hyman and use code HYMAN for 15% off your 90-day subscription Starter Kit. Get pure essential amino acids today. Go to bodyhealth.com and use HYMAN20 to get 20% off your first order. Try HTB Immune Energy Chews for yourself, visit bigboldhealth.com and use code DRMARK 25 at checkout to get 25% off your purchase today. Get a free LMNT Sample Pack with any order—just head to drinklmnt.com/hyman. Head to piquelife.com/hyman to get 20% off + a free beaker and frother today.

Lasting change begins with a shift in both mindset and behavior. Many people remain stuck in self-defeating patterns because of unconscious narratives, emotional triggers, and a disconnection from their body’s inner wisdom. Change isn’t just about willpower or information—it’s about learning to rewire the brain through small, intentional actions that generate powerful emotional feedback loops. Identity transformation happens not through repetition, but through experiences that create a sense of success. In a world flooded with conflicting advice and manipulative marketing, reclaiming agency requires tuning into your own signals, building self-trust, and recognizing that behavior change is a design challenge—not a character flaw. Empowerment comes from realizing that the ability to change is built into who we are as humans. In this episode, I speak with Tom Bilyeu, Dr. Rangan Chatterjee, and Dr. BJ Fogg about cracking the nut of behavior change. Tom Bilyeu is a filmmaker and serial entrepreneur best known as the co-founder of Quest Nutrition, a billion-dollar company built to combat metabolic disease through value-driven innovation. After nearly a decade of chasing financial success and feeling unfulfilled, he realized the importance of loving the struggle itself. This insight led him and his partners to shift focus from profit to purpose. Quest quickly became the second fastest-growing company in North America, according to Inc. Magazine. After achieving significant personal wealth, Tom turned to the other global crisis he saw—disempowering mindsets. To address this, he co-founded Impact Theory, a media studio with his wife, Lisa Bilyeu. Their mission is to scale mindset transformation by producing empowering content that shifts the cultural subconscious. Just as Disney built the most magical place on Earth, the Bilyeus aim to build the most empowering one. Dr. Rangan Chatterjee is regarded as one of the most influential doctors in the UK. A practicing GP for the last two decades, Dr. Chatterjee wants to inspire people to transform their health by making small, sustainable changes to their lifestyles. Host of the #1 Apple podcast, Feel Better, Live More, and presenter of BBC 1’s Doctor in the House, Dr. Chatterjee is the author of 5 Sunday Times bestselling books and his TED Talk, “How to Make Diseases Disappear,” has now been viewed over 4.8 million times. His newest book is Happy Mind, Happy Life: The New Science of Mental Well-Being. Dr. BJ Fogg is a behavior scientist, author, and founder of the Behavior Design Lab at Stanford University, where he has researched human behavior since 1998. He developed the groundbreaking “Behavior Design” system, which explains how behavior works and how to design it effectively. Over the past decade, his lab has focused on practical applications—from helping people navigate coronavirus-related challenges to training climate change professionals in behavior change strategies. BJ is also the creator of the “Tiny Habits” method, a simple, science-backed approach to habit formation that has helped over 40,000 people make lasting life changes. His work empowers individuals and organizations to design behavior that benefits both people and the planet. He shares his insights in the New York Times best-selling book, Tiny Habits: The Small Changes That Change Everything. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: Why Your Mindset Matters If You Want Health And WealthHow to Make Change That Lasts with Dr. Rangan ChatterjeeHow to Make Behavior Change Stick

With so many supplements on the market, how do you know what’s actually worth taking—and what’s just a waste of money? In this episode of The Dr. Hyman Show, I sit down with Steve Martocci, a tech entrepreneur who’s applying smart tools and real data to help people finally make sense of their supplements. We talk about why most people still aren’t getting the nutrients they need—even if they’re taking vitamins—and how Steve’s new platform, SuppCo, is making it easier to figure out what to take, what to skip, and what to trust. You’ll learn: • Why 70% of people are still low in at least one important nutrient (and how that affects your energy, mood, sleep, and more) • The truth about getting everything you need from food (and why that’s harder than it sounds) • How to spot low-quality supplements and avoid harmful fillers and contaminants • Why your doctor may not know how supplements interact with your medications • How to SuppCo’s app can help you track all your supplements, avoid taking too much of certain nutrients, and personalize your health routine (BTW, when you download the SuppCo app, you can view my personal supplement Stack and Protocols). If you take supplements—or are thinking about it—this episode will help you do it smarter, safer, and more effectively. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive +++ SPONSOR COPY This episode is brought to you by Big Bold Health, Timeline, AirDoctor, and Sunlighten. Try HTB Immune Energy Chews for yourself, visit bigboldhealth.com and use code DRMARK 25 at checkout to get 25% off your purchase today. Support essential mitochondrial health and save 10% on Mitopure. Visit timeline.com/drhyman to get 10% off today. Get cleaner air. Right now, you can get up to $300 off at airdoctorpro.com/drhyman. Visit sunlighten.com and save up to $1400 on your purchase with code HYMAN.

Up to 80% of people may be living with insufficient levels of vitamin D, magnesium, and omega-3 fatty acids—three essential nutrients involved in critical functions like immune defense, cardiovascular health, mood regulation, and brain function. Modern lifestyles—marked by nutrient-poor diets, low sun exposure, chronic stress, and overuse of medications—disrupt the body’s ability to absorb and maintain these key nutrients. Deficiencies often go undiagnosed due to outdated testing, yet they’re strongly linked to conditions like depression, fatigue, diabetes, and heart disease. In this episode, I talk about, along with Andrew Huberman, how modern lifestyles and diets lead to widespread nutrient deficiencies and chronic disease—and how targeted nutrition and lifestyle changes can restore optimal health. Dr. Andrew Huberman is a neuroscientist and tenured Professor in the Department of Neurobiology at the Stanford University School of Medicine. He has made numerous important contributions to the fields of brain development, brain function, and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills, and cognitive functioning. Dr. Huberman is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award in 2017, which is given to the scientist making the largest discoveries in the study of vision. His lab’s most recent work focuses on the influence of vision and respiration on human performance and brain states such as fear and courage. Work from the Huberman Laboratory at Stanford University School of Medicine has been published in top journals including Nature, Science, and Cell and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: Do you need to take Vitamin D? How Magnesium Deficiency Impacts Your HealthHow to Rewire Your Brain For Sleep

Cory Richards has summited Everest without oxygen, survived avalanches, and photographed some of the world’s most remote regions. But his most grueling expeditions didn’t happen on a mountain—they happened within. In this revealing episode of The Dr. Hyman Show, you’ll hear how a life shaped by mental health struggles, institutionalization, and homelessness led Cory to push the limits of endurance—and how those experiences can offer powerful lessons on healing and self-discovery. We explore: • Why big achievements don’t guarantee fulfillment—and what actually does • How spending time in nature and solitude can help you reconnect with yourself and find clarity • What Cory’s journey through trauma and recovery can teach you about your own capacity to heal • Why creativity, purpose, and self-reflection are essential tools for building a meaningful life Don’t miss this powerful conversation about what it really takes to overcome adversity. View Show Notes From This EpisodeGet Free Weekly Health Tips from Dr. Hymanhttps://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcastSign Up for Dr. Hyman’s Weekly Longevity Journalhttps://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcastJoin the 10-Day Detox to Reset Your Healthhttps://drhyman.com/pages/10-day-detoxJoin the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive This episode is brought to you by Seed, BON CHARGE, Paleovalley, and Pique. Visit seed.com/hyman and use code 25HYMAN for 25% off your first month of Seed's DS-01® Daily Synbiotic. Go to boncharge.com and use code DRMARK to save 15% on your PEMF mat today. Get nutrient-dense, whole foods. Head to paleovalley.com/hyman for 15% off your first purchase. Head to piquelife.com/hyman to get 20% off + a free beaker and frother today.

Cutting-edge medical advances are unlocking new ways to slow aging and enhance health. Plasmapheresis removes harmful inflammatory molecules, toxins, and cellular waste from plasma, helping to reduce biological aging and improve resilience. Muse cells, a powerful form of stem cell therapy, show promise in regenerating tissue and treating complex conditions like ALS and stroke. And peptides—small, naturally occurring signaling molecules—support healing, immune balance, and cellular repair, offering practical tools for longevity and optimized health. In this episode, I talk with Dr. Darshan Shah, Dr. Adeel Khan, and Dr. Edwin Lee about medical advancements that are the ultimate longevity biohacks. Dr. Darshan Shah is a board-certified surgeon, longevity medicine expert, author, and founder of Next Health—the world’s largest Health Optimization and Longevity clinic. He has performed over 20,000 surgical procedures and advised thousands on extending healthspan and lifespan. A prodigy in medicine, Dr. Shah earned his MD at 21 and trained at the Mayo Clinic. He has since launched multiple health ventures, authored a book, and patented medical devices. Committed to ongoing learning, he holds alumni status at Harvard Business School and Singularity University. Dr. Shah is a sought-after speaker on health and longevity. Dr. Adeel Khan, M.D. is a cell and gene therapy specialist with a visionary approach that is changing the way we perceive healthcare worldwide. Khan has cemented his reputation as a regenerative medicine expert and a driven entrepreneur. Dr. Edwin Lee is a board-certified endocrinologist, author, and international speaker specializing in hormonal balance, regenerative, and functional medicine. He founded the Institute for Hormonal Balance in Orlando in 2008 and completed fellowships in Critical Care and Endocrinology at the University of Pittsburgh. Dr. Lee is the lead investigator of an IRB-approved senolytic study exploring compounds like Dasatinib, Quercetin, and Fisetin, and recently published the first human trial using BPC157 for knee pain. He is an assistant professor at the University of Central Florida College of Medicine, co-founder of the Clinical Peptide Society, and founder of SavePeptides.org. His latest book is The Fountain of Youth with Peptides. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: This Breakthrough Blood Therapy Could Add Years To Your LifeStem Cells & Peptides: The Secret to Reversing Chronic Pain and Aging?How Peptides Enhance Healing and Longevity

Who in the world would try to lower their cholesterol by eating an entire sleeve of Oreos every day for a month? Meet Nick Norwitz, PhD, an Oxford graduate and Harvard medical student who did just that—in an effort to test a hypothesis about cholesterol and metabolic health. After reversing a serious inflammatory condition with a ketogenic diet, Nick saw his LDL cholesterol spike. Instead of panicking, he turned to research—and self-experimentation—to better understand what those numbers really meant. In this episode of The Dr. Hyman Show, we explore: • The health crisis that led Nick to a ketogenic diet • Why his LDL cholesterol jumped—and what questions it raised • The Oreo experiment and what it did (and didn’t) reveal • The nuance around LDL, metabolic health, and cardiovascular risk • What the science—and Nick’s own experience—suggests about meat, veganism, and finding a diet that works Check out the episode to hear this fascinating conversation. View Show Notes From This EpisodeGet Free Weekly Health Tips from Dr. Hymanhttps://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcastSign Up for Dr. Hyman’s Weekly Longevity Journalhttps://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast

There has been a fundamental shift in understanding metabolic health and chronic disease, particularly Type 2 diabetes, challenging long-standing dietary dogma by emphasizing that insulin resistance is largely driven by overconsumption of refined carbohydrates, not dietary fat or red meat. While highlighting the success of carbohydrate restriction and ketogenic approaches, nutrition is being seen as a powerful tool for reversing diabetes—often more effective and sustainable than conventional medication. The implications are far-reaching, not only for individual health outcomes, but also for reshaping public health strategies in addressing today’s chronic disease epidemic. In this episode, I speak with Gary Taubes, Sami Inkinen, and Dr. Greeshma Shetty about an approach to treating Type 2 Diabetes that works. I also discuss how red meat is not to blame, but we should be looking at high sugar and starch diets. Gary Taubes is an award-winning science and health journalist, and co-founder and director of the Nutrition Science Initiative (NuSI). He is the author of The Case Against Sugar, Why We Get Fat, Good Calories, Bad Calories, and, most recently, The Case for Keto. Gary is a former staff writer for Discover and correspondent for Science. He has written three cover articles on nutrition and health for The New York Times Magazine, and his writing has also appeared in The Atlantic, Esquire, and numerous "best of" anthologies, including The Best of the Best American Science Writing (2010). He has received three Science in Society Journalism Awards from the National Association of Science Writers, and is also the recipient of a Robert Wood Johnson Foundation Investigator Award in Health Policy Research. He lives in Oakland, CA. Sami Inkinen is the CEO and Co-Founder of Virta Health, a pioneer in reversing diseases like obesity and type 2 diabetes through a nutrition-first approach. Sami's personal connection to diabetes and passion to advance global health was the motivation behind Virta and its innovative care model. Previously, Inkinen was the co-founder of the leading online real estate marketplace Trulia, serving as its COO and president and board member until its IPO and eventual sale to Zillow Group. Dr. Greeshma Shetty, board certified in Internal Medicine and Endocrinology, currently serves as a Lead Clinician in the Virta Medical Group and the Director of Quality and Safety at Virta Health. Prior to joining Virta, she was clinical physician educator at Harvard Medical School, where she directed the combined Joslin - Beth Israel Deaconess Endocrine Fellowship program and Co-Directed the Asian American Diabetes Initiative. She is dedicated to clinical excellence, leveraging health technology, transforming healthcare delivery, driving health equity and building high performing teams. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: The Evolution of Diabetes Treatment How to Reverse Diabetes Naturally Does Red Meat Cause Type II Diabetes?

We all know emotional maturity is essential for a healthy relationship—but how do you actually get there? In this episode of The Dr. Hyman Show, I talk with Diego Perez, the #1 New York Times bestselling author known as Yung Pueblo, about the small mindset shifts that can make a huge difference in how you show up for yourself and your partner. Drawing from his new book, How to Love Better, Diego shares how to stop repeating the same old patterns and start building relationships grounded in awareness, honesty, and real emotional growth. In this conversation, we explore: Why emotional maturity is the #1 skill for resolving conflict How letting go of control can lead to more trust, connection, and ease in your relationship How your old emotional patterns might be causing tension you don’t even realize Why owning your emotions can help you avoid blame and grow together Simple mindset shifts that can make love feel more secure, stable, and honest Check out the episode for a practical, compassionate guide to loving better. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast This episode is brought to you by Sunlighten, Timeline Nutrition, Paleovalley, and LMNT. Visit sunlighten.com and save up to $1400 on your purchase with code HYMAN. Support essential mitochondrial health and save 10% on Mitopure. Visit timeline.com/drhyman to get 10% off today. Get nutrient-dense, whole foods. Head to paleovalley.com/hyman for 15% off your first purchase. Get a free LMNT Sample Pack with any order—just head to drinklmnt.com/hyman.

Many people struggle with mysterious symptoms like fatigue, brain fog, food sensitivities, and skin issues—only to be misdiagnosed or dismissed altogether. This conversation highlights how histamine intolerance and mast cell activation syndrome can be the hidden drivers behind a wide range of chronic conditions, and why they're often overlooked in conventional medicine. From the role of gut health, food triggers, and environmental toxins to deeper root causes like Lyme disease or mold exposure, it’s clear that personalized, Functional Medicine is key to uncovering real answers. Understanding the immune system’s role in histamine reactions—and how even “healthy” foods can be inflammatory for some—is a critical step toward healing. In this episode, I talk with Dr. Todd LePine, Dr. Elizabeth Boham, and Dr. Mark Pimentel about what histamine intolerance is, how it can be related to gut health, and why it’s important to address it. Dr. Todd LePine graduated from Dartmouth Medical School and is Board Certified in Internal Medicine, specializing in Integrative Functional Medicine. He is an Institute for Functional Medicine Certified Practitioner. Prior to joining The UltraWellness Center, he worked as a physician at Canyon Ranch in Lenox, MA, for 10 years. Dr. LePine’s focus at The UltraWellness Center is to help his patients achieve optimal health and vitality by restoring the natural balance to both the mind and the body. His areas of interest include optimal aging, bio-detoxification, functional gastrointestinal health, systemic inflammation, autoimmune disorders, and the neurobiology of mood and cognitive disorders. Dr. LePine enjoys skiing, kayaking, hiking, camping, and golfing in the beautiful Berkshires, and is a fitness enthusiast. Dr. Elizabeth Boham is Board Certified in Family Medicine from Albany Medical School, and she is an Institute for Functional Medicine Certified Practitioner and the Medical Director of The UltraWellness Center. Dr. Boham lectures on a variety of topics, including Women’s Health and Breast Cancer Prevention, insulin resistance, heart health, weight control and allergies. She is on the faculty for the Institute for Functional Medicine. Dr. Mark Pimentel is a Professor of Medicine and Gastroenterology through the Geffen School of Medicine and an Associate Professor of Medicine at Cedars-Sinai. Dr. Pimentel is also the Executive Director of the Medically Associated Science and Technology (MAST) program at Cedars-Sinai, an enterprise of physicians and researchers dedicated to the study of the gut microbiome in order to develop effective diagnostic tools and therapies to improve patient care. Dr. Pimentel has over 150 publications in many high-profile journals, and he is the author of the book, The Microbiome Connection: Your Guide to IBS, SIBO, and low fermentation eating. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: Is Histamine Intolerance The Cause Of Your Mysterious Symptoms? What is Histamine Intolerance? Surprising Symptoms You Need to Know IBS: It’s Not In Your Head—Advances In Diagnosing And Treating, Bloating And Tummy Troubles

Ultra-processed food is the new cigarette—and it's fueling a global health crisis hiding in plain sight. In today’s episode, I’m joined by Dr. Chris van Tulleken—infectious disease physician, BBC broadcaster, and author of Ultra-Processed People—to expose the truth behind ultra-processed foods and the industries driving their consumption. To find out what this food is really doing to us, Dr. van Tulleken became the first subject in a groundbreaking clinical trial—eating 80% of his calories from ultra-processed food for a full month. We unpack what makes ultra-processed food fundamentally different from real food—even when the ingredients look similar, and why its impact on your brain, metabolism, and long-term health is far worse than anyone thought… You’ll learn: How ultra-processed food hijacks your brain’s reward system The science behind food addiction and satiety hormones Why food labels and front-of-package claims are designed to mislead you What the latest data says about UPFs and 32 chronic diseases The global policy movements and lawsuits now underway to fight back This episode is part science, part exposé, and a wake-up call for anyone who thinks food is just about calories and willpower. If you care about your health, your kids, or the future of our food system, you need to hear this. https://linktr.ee/ultraprocessedpeople View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast

Sleep is not just a luxury—it’s a foundational pillar of health that influences nearly every aspect of our well-being. Sleep deprivation doesn’t just cause fatigue; it disrupts hormones, drives inflammation, damages metabolism, and accelerates aging. From the gut microbiome to stress hormones like cortisol, sleep is deeply intertwined with brain, immune, and metabolic health. Yet our modern world—filled with late-night screens, ultra-processed foods, and chronic stress—works against quality rest. In this episode, I discuss, along with Dr. Matt Walker and Shawn Stevenson, why we need to address sleep as a core health priority to unlock healing, prevention of chronic disease, and renewed vitality. Matthew Walker earned his PhD in neuroscience from the Medical Research Council in the UK, and subsequently became a Professor of Psychiatry at Harvard Medical School. He is currently a Professor of Neuroscience and Psychology at the University of California, Berkeley, and director of the Center for Human Sleep Science. Matt’s research focuses on the effect of sleep on human health and disease, brain, and body. He has published more than 100 scientific research studies and has received numerous funding awards from the National Science Foundation and the National Institutes of Health. Matt has given a main-stage TED Talk that has been viewed over 13 million times, has also created several TED Miniseries on sleep, a MasterClass series on sleep, and is author of the New York Times bestseller, Why We Sleep. Matt is also the host of the 5-star-rated, The Matt Walker Podcast. Shawn Stevenson is the author of the USA Today National bestseller Eat Smarter, and the international bestselling book Sleep Smarter. He’s also the creator of The Model Health Show, featured as the number #1 health podcast in the U.S. with millions of listener downloads each month. A graduate of the University of Missouri–St. Louis, Shawn studied business, biology, and nutritional science and became the cofounder of Advanced Integrative Health Alliance. Shawn has been featured in Forbes, Fast Company, The New York Times, Muscle & Fitness, ABC News, ESPN, and many other major media outlets. This episode is brought to you by BIOptimizers. Head to bioptimizers.com/hyman and use code HYMAN10 to save 10%. Full-length episodes can be found here: How to Optimize Your Sleep with Dr. Matthew Walker How To Stay Asleep And Sleep More Deeply Hack Your Sleep

Are U.S. food companies cutting corners at the expense of your health? Vani Hari, known to many as the Food Babe, thinks so—and she’s spent over a decade sounding the alarm. In this episode of The Dr. Hyman Show, she shares why she believes many American products are still made with harmful additives and dyes, even though companies have found ways to remove them in versions sold abroad. In our conversation, she explains: Why she believes Kellogg’s and other U.S. brands aren’t doing enough to protect American consumers. The FDA loophole she says allows companies to self-approve food chemicals without oversight. How food dyes could be contributing to rising rates of behavioral issues in kids. The labeling gaps and industry tactics she says are keeping consumers in the dark. How everyday people can push back—and why she believes activism still works. Don’t miss this insightful episode! View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast This episode is brought to you by Sunlighten, Timeline Nutrition, Big Bold Health, and PaleoValley. Visit sunlighten.com and save up to $1400 on your purchase with code HYMAN. Support essential mitochondrial health and save 10% on Mitopure. Visit timeline.com/drhyman to get 10% off today. Try Big Bold Health’s HTB Rejuvenate and get 25% off by going to bigboldhealth.com and use code DRMARK25 at checkout. Get nutrient-dense, whole foods. Head to paleovalley.com/hyman for 15% off your first purchase.