The Pound of Cure Weight Loss Podcast

What if your struggle with weight loss isn't about willpower at all, but about brain patterns you were born with? In this groundbreaking conversation, Dr. Matthew Weiner and registered dietitian Zoe sit down with neuroscientist Dr. Steve Rondeau, who has conducted over 50,000 EEG brain scans and just released his book Think Like a Brain. Dr. Rondeau reveals that emotional eating, stress eating, and food cravings aren't character flaws—they're measurable brain patterns that show up differently in every person. His research has identified that what we call "stress eating" can manifest in 4,096 different combinations of brain patterns, explaining why the same diet works for one person but fails for another. One of the most exciting revelations is the potential to use brain scans to predict who will respond to GLP-1 medications like Ozempic, Wegovy, and Zepbound before they even take their first dose. Dr. Rondeau discusses the "overwhelmed pattern"—a specific brain biomarker where brain activity slows down under stress, strongly correlated with using food as an escape mechanism. He draws fascinating parallels between GLP-1 medications and psychedelic therapy, explaining how both create a window of opportunity where the usual noise quiets down enough for real behavioral change to happen. The key is using that window effectively with proper integration work. This episode challenges the entire foundation of mental health diagnosis, revealing why the DSM is fundamentally flawed and how brain scan technology can finally match treatments to individual biology rather than broad symptom categories. Dr. Rondeau uses the powerful analogy of a husky in the desert versus the mountains—your brain patterns may be perfectly adapted for certain situations but set you up for failure in others. The conversation explores emerging wearable EEG technology, the inheritance of brain patterns, and the future of truly personalized medicine. Essential listening for anyone who has ever wondered why willpower never seems to be enough. Connect with Dr. Steve Rondeau: thinklikeabrain.comDownload the Pound of Cure App: gololi.ai - AI-powered personalized weight loss planning

In this inspiring episode, Moira shares her transformative journey through weight loss, bariatric surgery, and lifestyle changes. Discover practical strategies for sustainable health, the importance of exercise safety, and how combined treatments can empower lasting weight management. Sign up to beta test our new app! gololi.ai

In this episode, Dr. Weiner and Zoe discuss the latest advancements in obesity medicine, including the beta launch of their new app Loli, the evolution of GLP-1 medication dosing with the Quick Pen, and insights from recent research on GLP-1 prescribing practices. They also address patient questions on post-bariatric care and the future of medication delivery. Sign up to be a beta tester for our new app - https://gololi.ai

In this candid patient interview, Taylor Hultquist shares her complete bariatric surgery journey one year post-op, revealing the physical, mental, and emotional transformations that extended far beyond the number on the scale. This episode covers the real, unfiltered experience of bariatric surgery including: Post-Surgery Physical Changes: Taylor discusses her weight loss progress, strength training routine, and unexpected non-scale victories like hiking without knee pain and jogging for the first time in years. She breaks down what recovery actually looked like and the physical milestones that mattered most. Mental Health Improvements After Weight Loss Surgery: One of the most significant aspects of Taylor's journey was the dramatic reduction in anxiety and depression symptoms post-surgery. She shares how her mental clarity improved and why the psychological benefits were just as important as the physical changes. The Importance of Personal Choice in Bariatric Surgery: Taylor emphasizes that the decision to undergo weight loss surgery must be entirely personal. She discusses how to navigate pressure from family members, set healthy boundaries around weight discussions, and advocate for yourself throughout the process. Mindful Eating and Body Awareness Post-Op: Learn how Taylor developed new relationships with food and hunger cues after surgery. She shares practical strategies for mindful eating, recognizing fullness signals, and adjusting to her body's new needs and limitations. Non-Scale Victories and Redefining Success: Beyond weight loss numbers, Taylor celebrates the smaller wins that transformed her daily life - from increased energy levels to improved mobility to newfound confidence in social situations. These victories became the foundation of her sustainable transformation. Setting Boundaries with Loved Ones: Taylor provides honest advice about communicating needs to family and friends, especially when it comes to unsolicited weight loss advice or commentary. She discusses how setting clear boundaries protected her mental health during a vulnerable time. Strength Training and Physical Activity Post-Surgery: Discover how Taylor incorporated strength training into her routine and why building muscle became a priority. She shares her approach to exercise that focuses on feeling strong rather than just losing weight. This patient success story offers valuable insights for anyone considering bariatric surgery, currently in their post-op journey, or supporting a loved one through weight loss surgery. Taylor's transparency about both challenges and triumphs provides a realistic perspective on what life looks like after this major medical decision. Whether you're researching gastric sleeve, gastric bypass, or other bariatric procedures, this conversation covers the topics that matter most: mental health support, realistic expectations, lifestyle changes, body image struggles, and the ongoing process of self-improvement after surgery. Connect with Pound of Cure Weight Loss Podcast: New episodes released weekly featuring expert interviews, patient stories, and evidence-based weight loss strategies from Dr. Matthew Weiner and registered dietitian Zoe. For more information about bariatric surgery, GLP-1 medications, nutrition counseling, and sustainable weight loss approaches, visit our practice or check out previous episodes on metabolic health, set point theory, and medical weight loss options. Visit our website. Vote for Linda Jones to be on the cover of Ms. Health & Fitness 2026 here.

After getting completely hacked and losing our entire social media presence, we're pivoting HARD - and it might be exactly what we needed. In this raw, unfiltered episode, Dr. Matthew Weiner and Zoe break down: - WHY we stopped prescribing the "new" Wegovy pill (spoiler: it's 5 years old and we have data you need to hear) - The GLP-1 medication coming in 2026 that could change everything - Retatrutide clinical trial results revealed - How to get REAL Eli Lilly medication for $150/month (not compounded) through a program most people don't know exists - The AI-powered weight loss app Dr. Weiner is coding himself that does what he does in the office (beta testers wanted!) - Why we're ditching Instagram for Reddit and YouTube - and the surprising reason long-form content beats 30-second clips PLUS: Real patient stories including a VSG + breast cancer + GLP-1 combination success, the truth about oral vs. injectable semaglutide, home-ground flour health claims investigated, and why that "bulge" when you cough isn't what you think it is. If you're on GLP-1s, considering them, or just tired of BS weight loss advice - this episode cuts through the noise with real data, real experience, and real talk. Like, subscribe, and share with someone who needs to hear this (since we can't share it on Instagram anymore)

What does the future of weight loss and obesity care really look like? In this special annual predictions episode of the Pound of Cure Weight Loss Podcast, Dr. Matthew Weiner, registered dietitian Zoë, and Deidre review their 2025 weight loss predictions and share bold, evidence-based predictions for 2026. They break down what’s coming next in GLP-1 medications, including pricing, insurance coverage, injectable vs oral GLP-1s, and how medications will increasingly be combined with nutrition, lifestyle changes, and bariatric surgery. The episode also explores major shifts in nutrition trends, including why protein quality will matter more than quantity, why fiber may be the next big focus, and how whole-food diets outperform processed “GLP-1 support” products. You’ll also hear forward-looking conversations about: • AI-powered meal planning and obesity care • Personalized nutrition tools and body composition tracking • Maintenance-phase weight loss becoming its own specialty • The future role of bariatric surgery alongside GLP-1 medications • Why sustainable habits matter more than ever This episode is ideal for anyone using or considering GLP-1 medications, navigating insurance coverage, or looking for realistic, long-term weight loss strategies grounded in science—not trends. Download our FREE APP from your app store today: Search "Pound of Cure"

In this powerful patient interview, Ray and Lisa open up about more than 25 years of weight management struggles, even while “eating like a mouse” and strictly following traditional dieting guidelines. They describe the emotional toll of feeling like their bodies were working against them—until they finally learned about food noise, the brain-driven hunger signals that make portion control and willpower-based dieting nearly impossible. Guided by their PCP and cardiologist, they began a GLP-1 medication and immediately discovered that their challenges weren’t due to lack of discipline but physiology. They explain how GLP-1 therapy helped quiet food noise, curb impulse eating, and make portion control feel natural for the first time in decades. But their transformation didn’t come from medication alone. Ray and Lisa share how combining GLP-1s with consistent strength training, intentional daily movement, balanced nutrition, and sustainable habits led to life-changing results — from better cholesterol and blood pressure to increased stability, stamina, and the ability to fully engage with their grandchildren again. Their story is a relatable, inspiring roadmap for anyone navigating weight loss after 40, metabolic changes, thyroid issues, menopause, emotional eating, or long-term dieting frustration. This episode highlights the science behind food noise, the importance of muscle maintenance on GLP-1s, and why a whole-body, personalized approach creates lasting change. Download the free Pound of Cure Weight Loss app from your app store today!

In this episode of the Pound of Cure Weight Loss Podcast, Dr. Matthew Weiner breaks down the surprising connection between gastric bypass surgery and alcohol metabolism. You’ll learn why a single drink can hit harder post-op, how the altered digestive system impacts blood alcohol levels, and what this means for addiction risk after surgery. If you’ve had bariatric surgery—or work with patients who have—this episode offers must-know insights into post-surgery physiology, safety, and long-term success. Whether you’re questioning if you can still enjoy alcohol or are concerned about the risk of transfer addiction, Dr. Weiner separates myth from fact in a way only he can. Download our FREE app from your app store today. Search "Pound of Cure"!

In this episode, Dr. Matthew Weiner takes a bold look at the future of healthcare — predicting that by 2030, the current U.S. healthcare payment system could collapse under its own weight. But instead of doom and gloom, he explores why this shift might actually improve patient care, reduce costs, and finally force the system to prioritize quality over profit. You’ll learn: If you’ve ever wondered why healthcare feels broken — and what it might take to fix it — this episode is for you. Learn more about our Platinum Program here. Download our FREE APP today - search "Pound of Cure Weight Loss" in your app store!

In this episode of the Pound of Cure Weight Loss Podcast, Dr. Matthew Weiner and long-time surgical partner Deidre Schodroski dive deep into the real-world challenges bariatric patients face after surgery. From the surge in heartburn after gastric sleeve procedures to long-term PPI use, iron deficiencies, protein shake intolerance, hypoglycemia, and muscle loss—this episode delivers practical, science-backed solutions for every stage of the journey. They also discuss the synergistic benefits of combining GLP-1 medications with bariatric surgery, how to manage complications, and why technology like the Pound of Cure app and Sage, the AI dietitian, is transforming personalized weight loss care. If you’ve ever felt lost in the complexity of postop life or medications, this conversation offers clarity, direction, and support. - Discover why PPIs aren't always the enemy - Learn how to build muscle after surgery - Understand how meds + surgery = better results - Get protein shake tips that actually work for your gut - Start using our free app to optimize your care Learn more about how POC can help you: https://poundofcureweightloss.com/

In this episode of the Pound of Cure Weight Loss Podcast, Chef Healthy Henry shares his journey from a culinary background to becoming a nutrition advocate after undergoing bariatric surgery. He discusses his philosophy of healthy eating, the importance of meal prep, and introduces his innovative 'Protein Flip' method, which emphasizes a balanced approach to protein and fiber. The conversation also touches on the role of plant proteins, the use of AI in cooking, and the significance of eating with purpose. Follow Chef Henry on Instagram and check out his website here. Download the Pound of Cure app from your app store for free today!

In this episode of the Pound of Cure Weight Loss Podcast, Dr. Matthew Weiner and registered dietitian Zoë dive into some of the most talked-about topics in the world of weight loss, nutrition, and healthcare innovation. They unpack the growing influence of AI in healthcare — including how it powers the Sage AI Dietitian in the Pound of Cure app — and why AI may be the future of accessible, personalized nutrition support. They also break down the "protein obsession" sweeping the food industry and explore why more protein isn’t always better, especially when it’s coming from ultra-processed sources like whey protein bars and shakes. This episode also tackles: Whether you’re post-op, on GLP-1s, or just trying to make smarter nutrition choices, this episode brings nuance, compassion, and clarity to a space often dominated by judgment and diet culture myths. Download the Pound of Cure App today! Free on the app store.

In this episode of the Pound of Cure Weight Loss Podcast, Dr. Matthew Weiner and registered dietitian Zoë answer listener questions covering some of the most common — and most misunderstood — challenges in the weight loss journey. They break down how to set a realistic goal weight based on body composition, not BMI, and explore why nutrition quality matters more than calorie counting. You’ll also learn what causes sugar cravings, how to manage hunger after bariatric surgery, and why ultra-processed foods are designed to keep you overeating. Whether you’re using GLP-1 medications, recovering from bariatric surgery, or trying to lose weight without extreme restriction, this episode gives you practical strategies grounded in real science — not diet culture myths. Download the free Pound of Cure App! Apple: https://apps.apple.com/us/app/a-pound-of-cure/id6741747271 Android: https://play.google.com/store/apps/details?id=com.digitalbariatrics.poundofcure

In this episode of the Pound of Cure Weight Loss Podcast, Dr. Matthew Weiner and registered dietitian Zoë dive deep into the latest research on GLP-1 medications and their evolving role in weight loss, muscle preservation, and even potential cancer treatment. They break down what the newest studies actually show — including why so many headlines are misleading, and how to interpret scientific research through a more critical lens. You’ll also learn why strength training is non-negotiable during GLP-1 therapy or bariatric weight loss, what to know about oral semaglutide vs. injectable versions, and how nutrition plays a key role in maintaining muscle mass while losing weight. Whether you're a patient on Ozempic, Wegovy, Zepbound, or considering medication as part of your obesity treatment, this episode helps you make more informed, science-based decisions. Download our NEW FREE APP now! For Apple: https://apps.apple.com/us/app/a-pound-of-cure/id6741747271 For iOS: https://play.google.com/store/apps/details?id=com.digitalbariatrics.poundofcure

In this episode of the Pound of Cure Weight Loss Podcast, Dr. Matthew Weiner and Zoë discuss the recent updates to their podcast, including a new app launch and the integration of AI in weight loss strategies. Discover how AI is transforming the way we approach weight management, offering personalized guidance and amplifying the effectiveness of traditional methods. From meal planning to surgical decisions, learn how AI is set to provide answers and strategies that rival expert advice, paving the way for a more accessible and efficient weight loss journey. Tune in to understand the future of weight loss with AI and how it can support your health goals. They delve into various listener questions regarding GLP-1 therapy, post-surgery nutrition, and the implications of vaping on health. The conversation emphasizes the importance of a holistic approach to weight loss, combining medication, surgery, and lifestyle changes. Download the Pound of Cure app for free now! For Apple click here. For Android click here.

In this episode of the Pound of Cure Weight Loss Podcast, Julie shares her transformative journey with weight loss, detailing her struggles with insurance, medication, and the emotional toll of her experiences. She discusses the challenges of finding the right dosage of GLP-1 medication, the positive side effects she has experienced beyond weight loss, and the importance of understanding inflammation in weight management. Julie emphasizes the need for a supportive healthcare system and the liberation she feels from finally being in control of her health and relationship with food. Learn more about our Platinum Program here.

In this episode of the Pound of Cure Weight Loss Podcast, Dr. Matthew Weiner and Zoë discuss various topics related to weight loss, including the challenges surrounding obesity drugs, the impact of antidepressants on weight gain, and the effectiveness of bariatric surgery compared to GLP-1 medications. They emphasize the importance of individualized patient care, the flaws in the healthcare system, and the need for a comprehensive approach to weight management that includes nutrition, medication, and surgery when necessary. Learn more about the Platinum Program here.

In this episode of the Pound of Cure weight loss podcast, Zoë and Dr. Matthew Weiner address various listener questions regarding weight loss strategies, particularly focusing on post-surgery weight regain, the importance of fiber, the role of protein shakes, and the challenges faced by non-responders to weight loss treatments. They also discuss the broader issues within the healthcare system, including the impact of pharmaceutical companies and the need for reform. Learn more about our Platinum Program here. Chapters: 00:00 Introduction to Weight Loss Q&A 01:02 Post-Surgery Weight Regain and Lifestyle Changes 07:13 Protein Shakes and Weight Loss Stalling 12:16 Understanding Non-Responders to Weight Loss Medications 20:09 Addressing Healthcare System Issues 29:34 Future of Weight Loss Care and Community Support

In this episode of the Pound of Pure Weight Loss Podcast, hosts Zoë and Dr. Matthew Weiner discuss the evolving landscape of weight loss medications, particularly focusing on GLP-1 medications and the implications of recent changes in compounding laws. They explore the concept of microdosing these medications, highlighting its potential benefits and the importance of personalized patient care. The conversation emphasizes the need for innovative dosing strategies and the future of weight loss treatments in conjunction with nutrition and lifestyle changes. Interested in learning more about our Pound of Cure Platinum Program? Click here.

In this episode, Kelly shares her transformative journey through weight loss and bariatric surgery. Starting from her struggles with weight since childhood, she discusses her decision to undergo gastric bypass after experiencing the limitations of a lap band. Kelly reflects on the emotional challenges of weight regain and the pivotal moments that led her to seek a more effective solution. Post-surgery, she describes a complete lifestyle overhaul, emphasizing the importance of nutrition, exercise, and a positive mindset. The conversation highlights the significance of understanding obesity as a disease and the need for self-compassion in the weight loss journey. Learn more about how to become a patient with our nationwide Platinum Program here. Chapters 00:21 Kelly's Journey to Bariatric Surgery 01:41 The Emotional Impact of Weight Loss and Regain 08:27 Transitioning from Lap Band to Gastric Bypass 09:26 Life After Gastric Bypass: A New Beginning 16:46 Maintaining Weight Loss and Lifestyle Changes 20:42 Nutritional Strategies Post-Surgery 25:04 The Hormonal Connection in Weight Loss 29:39 Shifting Perspectives on Food and Nutrition 31:35 The Role of Exercise in Weight Management 33:49 Transformative Experiences and Self-Perception 34:23 Advice for Those Considering Weight Loss Surgery 37:29 The Importance of Research and Persistence