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Master Your Health Learn // Master // Achieve

Master Your Health Learn // Master // Achieve
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Master Your Health Learn // Master // Achieve






Interpersonal Neurobiology and the Power of Mindsight. Podcast with Dan Siegel

On this episode of humanOS Radio, I talk with Dan Siegel. Dr. Siegel is a clinical professor of psychiatry at the UCLA School of Medicine, and is the founding co-director of the Mindful Awareness Research Center at UCLA. He is a pioneer in a field known as interpersonal neurobiology (sometimes referred to as relational neuroscience). Interpersonal neurobiology characterizes human development and function as a product of interactions between the body, the mind, and relationships with one...


Sleep and DNA Repair. Podcast with Lior Appelbaum

Why do we sleep? This is a question that has bedeviled researchers for decades. But we think one major reason may be to facilitate DNA repair. In this episode of humanOS Radio, I speak with Lior Appelbaum. Dr. Appelbaum and colleagues have performed some elegant studies elucidating the molecular mechanisms that underlie sleep, using zebrafish as a model organism. In a recent study, the team engineered zebrafish larvae to express colorful tags on their chromosomes, making it easy to monitor...


Does Metformin Block the Health Benefits of Exercise? Podcast with Ben Miller

On this episode of humanOS Radio, we welcome Ben Miller to the show. Ben is a principal investigator in the aging and metabolism research program at the Oklahoma Medical Research Foundation. In his study, Miller and his team randomly assigned 53 participants to consume either placebo or metformin for 12-weeks, while completing a supervised aerobic exercise program. This exercise regimen elicited measurable improvements in blood sugar control, insulin sensitivity, and aerobic fitness for the...


Optimizing Your Gut Microbiome with Personalized Probiotics. Podcast with Richard Lin

On this episode of humanOS Radio, I speak with Richard Lin. Like all too many of us, Richard became personally invested in his health when he developed a problem that failed to respond to conventional medical interventions. He eventually realized that a disruption in the gut microbiota was the likely cause of his illness. This inspired him to start Thryve Inside. Thryve helps consumers test and learn about their own microbiota by providing at-home microbiome test kits. But here's what sets...


Increasing Mitochondrial Autophagy for Better Aging. Podcast with Davide D'Amico.

We associate getting older with a loss of energy. On the molecular level, this is quite literally true, because one of the hallmarks of aging is mitochondrial dysfunction. Mitochondria are often referred to as “the powerhouse of the cell,” because they convert nutrients from the food we eat into usable energy, in the form of ATP. But as we age, mitochondria become less effective at generating the energy we need for various chemical processes. So why does this happen? As with most things in...


Are You Biologically Older or Younger Than Your Chronological Age? Podcast with Ken Raj

We tend to think of age in terms of the number of years we have been alive - meaning our chronological age. But the year that you were born is not necessarily an accurate measure of your health or your life expectancy. We are coming to realize that a better predictor is your biological age - and that can be quite different from your chronological age. So how do you learn your biological age? And what can you do with this information? In this episode of humanOS Radio, I speak with Ken Raj....


Is the Ketone BHB (beta-Hydroxybutyrate) Good for Memory? With John Newman, MD, PhD

In this episode of humanOS Radio, I speak with John Newman. Dr. Newman is a geriatrician (a physician who specializes in the care of older people) at UCSF, as well as a professor at the Buck Institute for Research on Aging. He is chief investigator at the Newman Lab, where he is exploring ways to harness metabolic signals to promote health and resilience, particularly in older adults. Dr. Newman’s research focuses predominantly on ketone bodies - molecules produced in the liver when glucose...


Is the Paleo Diet Good or Bad for Aging? Podcast with Michael Rose.

Why do we age? The fundamental causes of aging at the molecular level are relatively well established. But the question of why aging happens in the first place is a more challenging one, one which has bedeviled evolutionary biologists and philosophers for years. You might think, intuitively, that the process of natural selection would gradually eliminate senescence. Aging increases mortality, and organisms that experience impaired function and ultimately die would not be able to produce as...


Studying Preindustrial Societies Informs us About How to Be Healthy. Podcast with Herman Pontzer

For the vast majority of human history, our species lived hunter-gatherer lifestyles. We can therefore learn much about how humans probably once lived by studying preindustrial societies. Research on preindustrial societies has consistently shown that these people have exemplary metabolic health. And when we consider that modern humans are succumbing to chronic diseases at an alarming rate, we clearly have much to learn from preindustrial people. In this episode of humanOS Radio, Greg Potter...


Research on Smartphones and Sleep (Prof. Jeanne Duffy from Harvard)

Do smartphones really affect the timing and quality of your sleep? In this episode of humanOS Radio, Dan speaks with Professor Jeanne Duffy from Harvard Medical School on her most recent research investigating this question.


An Introduction to Heart Rate Variability (HRV). Podcast with Phyllis Stein

Stress is something we all experience all too frequently. The effects of different stressors accumulate, and when the resultant load is excessive, we are at increased risk of a range of diseases. So, to avoid the amount of stress we experience exceeding our bodies’ capacities to cope, it would be useful to have a way to monitor how we’re responding to stressors. In the last few years, numerous wearable devices that claim to monitor how we’re responding to stress have become available, and...


Stephan Guyenet vs. Gary Taubes on the Joe Rogan Experience - Post Discussion

Nutrition is perhaps the most emotionally charged of all of the applied sciences. It’s not hard to see why. For one thing, all of us eat, meaning that every single one of us is personally invested in this topic, and we interact with it all the time. We all develop a sense of expertise, in a way that we might not for something a bit more removed from our daily life, like robotics or civil engineering. In addition, food is arguably the most powerful and primal motivator for animals, ourselves...


How to Perform Better at Work (Guest James Hewitt)

In this podcast, Greg Potter speaks with James Hewitt, who has a particular interest in how people can achieve sustainable high performance. In addition to his role as Chief Innovation Officer at Hintsa Performance, James is doing a PhD at Loughborough University, where his research focuses on how workers’ lifestyle and work patterns influence their wellbeing and performance. In this interview James shares many useful insights regarding how to perform better at work. This podcast also...


Ketones for Brain Injury? Podcast with Tommy Wood

Brain injury is more pervasive and problematic than many people think. Every day, about 150 people die from traumatic brain injury-related deaths in the US alone, and whether you participate in a contact sport, work in the military, or simply travel on roads, you may at some point suffer the kind of event that incites brain injury. The problem is that brain injury is associated with numerous negative health consequences, including mental health issues and diseases such as Parkinson’s....


Protein and Muscle Mass. Podcast with Stu Phillips

Whether you want to look great at the beach, perform better at sports, or ward off disease, it’s important to optimize your protein intake. This brings us to the latest episode of humanOS Radio, in which I speak with Professor Stu Phillips from McMaster University. Tune in to find out more!


Clearing Zombie-Like Senescent Cells Reserves Signs of Aging. Podcast with Paul Robbins

Aging is arguably the leading risk factor for chronic diseases in the modern world. We have historically thought of aging as an inexorable decline of function, driven by the passage of time - something that we simply have to accept, and that cannot be changed. But what if aging were actually a modifiable risk factor? Your chronological age, meaning the length of time that you have been alive, obviously cannot be changed. But we know that biological aging can vary significantly, even among...


Atomic Habits for Achieving Your Goals. Podcast with James Clear

Why is it so hard for us to make healthy lifestyle changes - even when we have the knowledge to do better? Most of us have a list of things we would like to change. Maybe you’d like to lose thirty pounds, or be able to do fifty pushups, or run a marathon. But each of these comes with a long list of associated behaviors - many of which aren’t intrinsically rewarding - that are required to achieve and maintain these goals. It’s no wonder the statistics on weight loss are so underwhelming. On...


Good Sleep Helps Reduce Oxidative Stress. Podcast with Mimi Shirasu-Hiza

Why do we need to sleep? Part of what makes sleep so fascinating, as a field of research, is that it is such an enigma. Sleep is a profoundly vulnerable state, leaving us at the mercy of predators and the environment, and unable to defend ourselves or our possessions. It's also largely unproductive. Yet we spend about a third of our life in slumber. Moreover, sleep also seems to be nearly universal in the animal kingdom. Indeed, we have yet to identify an animal that clearly does not sleep...


Can Enhancing Slow Wave Sleep Boost Your Brain Function? Podcast with Kristine Wilckens

All of us know that lack of sleep impairs cognitive performance. But we are now realizing that sleep quality, and how long that you spend in deeper restorative sleep, also plays an important role in brain function. Today on humanOS Radio, I talk to Kristine Wilckens. Kristine is an assistant professor in the Sleep and Chronobiology Center in the Department of Psychiatry at the University of Pittsburgh. Her research has focused on how sleep structure can be altered to enhance cognitive...


What Are Natural Wines? Podcast with Todd White of Dry Farm Wines

The subject of alcohol and health is complex. There is evidence that alcohol can be health-promoting, but more recent evidence has suggested it isn't healthy for humans in any amount. The ancient Greeks only drank their wine diluted. They believed that only barbarians would drink unmixed or undiluted wine as it would bring out a type of behavior that would cause mayhem. In this episode, Dan speaks with Todd White, CEO of Dry Farm Wines, to discuss and compare the differences between...