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Empowered Patient Podcast

Health, Home & Life

Empowered Patient Podcast with Karen Jagoda is a window into the latest innovations in digital health, the changing dynamic between doctors and patients, and the emergence of precision medicine. The show covers such topics as aging in place, innovative uses for wearables and sensors, advances in clinical research, applied genetics, drug development, and challenges for connected health entrepreneurs.

Empowered Patient Podcast with Karen Jagoda is a window into the latest innovations in digital health, the changing dynamic between doctors and patients, and the emergence of precision medicine. The show covers such topics as aging in place, innovative uses for wearables and sensors, advances in clinical research, applied genetics, drug development, and challenges for connected health entrepreneurs.


San Diego, CA


Empowered Patient Podcast with Karen Jagoda is a window into the latest innovations in digital health, the changing dynamic between doctors and patients, and the emergence of precision medicine. The show covers such topics as aging in place, innovative uses for wearables and sensors, advances in clinical research, applied genetics, drug development, and challenges for connected health entrepreneurs.






Impact of Advancements in Root Canal Therapy with Dr. Sonia Chopra Ballantyne Endodontics

Dr. Sonia Chopra, endodontist and Founder of Ballantyne Endodontics is an expert on alleviating tooth pain. Sonia points out the advantages of using the Sonendo GentleWave procedure to change outcomes and expectations of root canal pain. Not only is this procedure more effective and faster, but it also requires just one dental appointment instead of multiple visits, freeing up resources to handle more patients and respond more quickly to emergencies. Sonia elaborates, "It's really important...


Addressing the Growing Problem of Patient Health Record Accuracy with Gregg Church 4medica

Gregg Church is the President of 4medica, a 24-year-old company that is in the business of aggregating datasets to create an accurate longitudinal view of a patient's health record. The number of different legacy systems that were not initially designed for interoperability is only part of the problem. In the current environment, there is an average 20% duplication rate creating confusion for care providers and payers and potentially causing harm to the patient. Gregg elaborates, "It's...


Why Dentists Should Screen for Sleep Apnea with Dr. Kent Smith Sleep Dallas

Dr. Kent Smith, the Chief Executive Officer at Sleep Dallas, raises concerns about the impact of sleep disorders and untreated sleep apnea. He emphasizes that physicians don't always ask patients about the quality of their sleep and that dentists have more time with patients to explore the underlying reasons for inadequate deep sleep. Kent explains, "I think many in healthcare aren't aware that poor sleep or ineffective sleep or lack of sleep, or unhealthy sleep, can have a severe impact on...


Assessing Adaptive Immune Responses to Viruses to Inform Decisions about Vaccinations with Dr. Tomasz George Virax Biolabs

Dr. Tomasz George, Chief Scientific Officer of Virax Biolabs, has developed a novel test process that assesses adaptive immune responses to viruses. This information can inform decisions by patients and doctors on how to most effectively produce an immune response and boost personal protection from the next virus outbreak. An app delivers data about how an individual might respond to a virus and sends notices of specific viruses in a geographic location, along with links to diet and...


Whole-Genome Sequencing of Cancer Tissue Optimizing Clinical Decisions with Asaf Zviran C2i Genomics

Asaf Zviran is the CEO, CSO, and Co-Founder of C2i Genomics which is both a technology company and a diagnostic company. C2i is providing a decentralized, cloud-based platform that allows global genomic labs, health centers, and pharma companies to do whole-genome sequencing on cancer patient tissue or blood. This technology uses the genomic data to determine the best options for treatment and to monitor treatment response. Asaf explains, "The way that we look at the cancer detection is in...


Genetic Information Increasingly Being Considered Powerful Tool to Reduce Risk and Prevent Diseases with Noura Abul-Husn and Amy Sturm 23andMe

Dr. Noura Abul-Husn is the VP of Genomic Health, and Amy Sturm the Director of Population Health Genomics at 23andMe. With over 13 million customers, 23andMe has built a database that can provide customized and personalized genetic information to individuals that can indicate health predispositions. This kind of information can lead to strategies to reduce the risk of diseases, manage diseases more appropriately, and even prevent diseases. Noura explains, "Well, 23andMe has been delivering...


Bringing Digital Technology and AI to Care Managers and Healthcare Providers with Jamie Colbert MD Memora Health

Dr. Jamie Colbert is the Senior Vice President of Care Delivery at Memora Health, a technology company automating manual tasks and administrative functions that take up so much time for healthcare providers. It is creating an environment that promotes interoperability with existing electronic medical record systems and other sources of patient data to improve patient care and provide guidance for patients to self-manage their complex conditions. Jamie explains, "In terms of the support that...


Raising Awareness About Causes and Dangers of Clostridium Difficile with Christian Lillis Peggy Lillis Foundation

Christian Lillis is the Executive Director of the Peggy Lillis Foundation -PLF - is on a mission to raise awareness about the highly contagious disease Clostridium difficile and to get C. diff recognized as a nationally notifiable disease. The Foundation is also providing a nutrition and lifestyle guide to give patients the ability to know what to eat to prevent recurrence and help prevent C. diff and other infections. Chris explains, "We've had some polls done that show about a third of...


Digital Musculoskeletal Solution Bringing Relief from Acute and Chronic Pain Avoiding Opioids with Jim Pursley Hinge Health

Jim Pursley is the President of Hinge Health, which offers a digital musculoskeletal solution to help individuals alleviate pain, avoid surgery, and reduce the need for opioids for acute and chronic pain. Hinge is also shining a light on those struggling with neurological and mental health challenges and how those conditions are exacerbating chronic pain and driving abuse of opioids. Jim elaborates, "We have developed a solution that offers virtual physical therapy. It's the elegant...


Repressing Expression of Disease-Causing Genes with Dr. Arthur Suckow DTx Pharma

Dr. Arthur Suckow is the Co-Founder and CEO of DTx Pharma, in search of an approach to administering sRNA therapeutics using a solution of fatty acids, which every cell in the body has a mechanism to take up. Leveraging those mechanisms, receptors, and transporters, the DTx concept is to trick the cells into bringing the sRNA molecules in so they can repress the expression of disease-causing genes. Arthur explains, "Well, the one that everyone is familiar with now because it's on the front...


Opportunities for Using Care Guides to Support Medicare Patients with Dr. Carl Cameron MVP Health Care

Dr. Carl Cameron is the Chief Medical Officer at MVP Health Care, a health services company in the northeast, developing innovative solutions for Medicare enrollees to help them get the care they need by thinking of patients as consumers. Using Care Guides, MVP is solving problems and clarifying benefits for consumers to keep them healthy and out of the hospital. Carl explains, "One thing we did in trying to understand the customers, the potential customers of the health plan, is we tried...


Converting Liver Tumors into Low-Oxygen Environment to Activate Drug to Drive Cell Death with Dr. Ray Lee Teclison

Dr. Ray Lee is the CEO of Teclison, focused on overcoming the limitations of existing immunotherapy for treating liver cancer in part caused by the fact that the liver is a highly immunotolerant organ. The key is to make the tumor a low-oxygen environment and delivering a drug that only works on the tumor. Ray elaborates, "First, let me explain what the TATE represents. It stands for the Trans-arterial TEC-001 Embolization. TEC-001 is the pipeline compound we've been trying to develop. This...


Health Coaches Addressing Stress and Substance Abuse Using Power of Digital Tools with Clark Lagemann Avidon Health

Clark Lagemann is the CEO of Avidon Health, developing technologies for healthcare providers and payers in order to deliver personalized health improvement plans for employees. Health coaches deploy digital tools to address the challenges of substance abuse and stress in order to find the root causes of problems and find paths to behavior change. Clark explains, "Well, the first thing is you need to create a culture in which your employees feel comfortable sharing and speaking about the...


Treating Tumors Using Subtractive Approach to Remove Molecules Suppressing Immune System with Amir Jafri Immunicom

Amir Jafri is the CEO and Founder of Immunicom, targeting the molecules and proteins produced by cancer. Using a subtractive approach, Immunicom has developed technology intended to remove the elements that are suppressing the immune system and allowing the tumor to shield itself from the immune system. After treatment, patients in clinical trials are seeing immune cells infiltrate their solid tumor cancers. Amir explains, "What we will do is then design our own molecules that will...


Developing Biosimilars to Drive Down Costs and Incentivize Innovation with Ming Li Alvotech

Ming Li is the Chief Strategy Officer at Alvotech, a biosimilar-only company developing biosimilar drugs to provide lower-cost alternatives in the global marketplace. Biosimilars are analogous to generic medicines, but these drugs are complex molecules developed and produced out of living systems, requiring sophisticated manufacturing processes and often litigation. The bulk of success in biologics has been in oncology, immunology, gastrointestinal diseases, asthma, and osteoporosis. Ming...


Advancing Wearable Biometric Monitoring and Analysis Technology with Phillip Bogdanovich Cipher Skin

Phillip Bogdanovich is the CEO and Co-Founder of Cipher Skin, developing wearable biometric monitoring technology for a wide range of applications. Their BioSleeve is providing data without the wires generally required to collect bio-signals. Development is underway for using this next-to-skin device to be embedded into clothing to capture a variety of biometrics. Phillip explains, "Cipher Skin is a hardware-enabled SaaS tool. We're focused on providing really good patient outcomes and...


Targeting Hippo Pathway to Inhibit NF2 Mutant Cancers with Mark Manfredi Ikena Oncology

Mark Manfredi is the CEO and President of Ikena Oncology, which is exploring the Hippo Pathway and how it relates to the RAS Pathway and RAS Network in order to inhibit genes that are associated with cancer initiation, progression, and cancer cell survival. Ikena is learning a great deal about drugging these pathways for therapeutic intervention and therapeutic resistance for NF2 mutant cancers. Mark elaborates, "We're working on two interconnected pathways. One is called the Hippo Pathway,...


Inducing Immune Tolerance to Overcome Hurdles of Gene Therapy with Dr. Peter Traber Selecta Biosciences

Dr. Peter Traber is the Chief Medical officer at Selecta Biosciences, which is enabling and increasing the effectiveness of gene therapy by inhibiting the body's immune response. Their drug platform ImmTOR is a nano-encapsulated immunomodulatory drug that causes the immune system to be tolerant of antigens and inhibits the immune response. This approach may overcome an important hurdle in gene therapy and biologic therapy by allowing repeated dosing. Peter explains, "Our immune response is...


Applying AI to Radiology Enabling Holistic Approach for Radiologists with Dr. Ryan Lee Einstein Healthcare Network and Dr. Peter Seidensticker Bayer Radiology

Dr. Ryan Lee, Chairman of the Department of Radiology at the Einstein Healthcare Network, now part of Jefferson health, and Dr. Peter Seidensticker, the VP of Medical Affairs and Clinical Development at Bayer Radiology join me to talk about how Bayer's Calantic Digital Solutions is empowering radiologists. Applying AI to the workflow allows the radiologist to improve efficiency, reduce fatigue, and focus on the most important suspicious markers. Ryan explains, "You specifically asked about...


Treating Obstructive Sleep Apnea with Precision Oral Device with Len Liptak ProSomnus Sleep Technologies

Len Liptak is the Co-Founder and CEO of ProSomnus Sleep Technologies, which is providing new options for patients suffering from the chronic disease obstructive sleep apnea. This condition means that the airways are blocked while people are sleeping. The most common treatment is a CPAP device that pushes air through the blockage and down the throat to ensure the sleeper has access to oxygen. ProSomnus has designed a personalized noninvasive oral device that holds the jaw forward to create a...