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Medical Breakthroughs from Penn Medicine

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Medical Breakthroughs features the newest medical advancements in the areas of oncology, cardiology, neurology, orthopedics, and genetics featuring America's leading physicians and medical researchers from Penn Medicine.

Medical Breakthroughs features the newest medical advancements in the areas of oncology, cardiology, neurology, orthopedics, and genetics featuring America's leading physicians and medical researchers from Penn Medicine.
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United States

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ReachMD

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Medical Breakthroughs features the newest medical advancements in the areas of oncology, cardiology, neurology, orthopedics, and genetics featuring America's leading physicians and medical researchers from Penn Medicine.

Language:

English


Episodes

Are VADs the Answer to the Heart Failure Epidemic?

6/8/2018
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Host: Jennifer Caudle, DO Guest: Eduardo Rame, MD Following a successful ventricular assist device clinical trial, Dr. Jennifer Caudle is joined by Dr. Eduardo Rame, Medical Director of the Ventricular Assist Device Program and Associate Professor of Medicine at the Hospital of the University of Pennsylvania, to discuss how this innovative technology is improving survival rates and decreasing the risk of adverse effects, such as stroke, gastrointestinal bleeding, and infection, in heart...

Duration:00:18:00

FDA-Approved Gene Therapy Reverses Blindness in Children & Adults

4/23/2018
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Host: Jennifer Caudle, DO Guest: Jean Bennett, MD, PhD Guest: Albert Maguire, MD Power couple Drs. Jean Bennett and Albert Maguire discuss how their new therapy for the RPE65 gene, which causes retinal blindness, was recently approved by the FDA to become the first gene therapy treatment for a genetic disease in the United States and the first worldwide treatment for inherited blindness. Not only do they delve into the mechanics of the corrected gene injection, but they also explain...

Duration:00:13:30

When Your Patient Has a Spinal Deformity: Clinical Priorities

2/2/2018
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Host: Barnett Mennen, MD Guest: Comron Saifi, MD Spinal deformity places strain on the vertebrae and supporting muscles, tendons, ligaments, and tissues supporting the spinal column. The treatment and management of this condition becomes centrally important to maintain patient quality of life through functional mobility and activity levels. Host, Dr. Barry Mennen and Dr. Comron Saifi discuss the leading assessment and treatment options for spinal deformity. Dr. Saifi is an Assistant...

Duration:00:16:29

What to Know About a State-of-the-Art Approach to GIST Treatment

1/17/2018
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Host: Shira Johnson, MD Guest: Ronald DeMatteo, MD, FACS A Gastrointestinal Stromal Tumor (GIST) is a rare sarcoma that begins in the digestive tract or stomach, with an incident rate in the United States of approximately 4,000 to 6,000 cases per year. Since these tumors behave differently from other gastrointestinal cancers, they require a specialized treatment plan. Host Dr. Shira Johnson chats with Ronald DeMatteo, MD, FACS, Chair of the Department of Surgery and a surgical oncologist...

Duration:00:12:29

Penn Medicine Neurosurgery Expert on Focused Ultrasound for Essential Tremor

1/3/2018
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Host: Jennifer Caudle, DO Guest: Gordon Baltuch, MD, PhD Essential Tremor is one of the most common movement disorder, affecting an estimated 3% of the population or approximately 10 million individuals in the United States. A new technology, Focused Ultrasound offers an alternative to traditional surgery that requires no incision or opening of the skull. Host Dr. Jennifer Caudle is joined by Dr. Gordon Baltuch a professor of Neurosurgery and director of the Penn Center for Functional...

Duration:00:11:29

CAR-T Cell Therapy: A Breakthrough Treatment for Fighting Cancer

10/23/2017
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Host: Shira Johnson, MD Guest: Robert Vonderheide, MD For years, the foundations of cancer treatment, surgery, chemotherapy, and radiation therapy were utilized with the objective of weakening cancer. But over the past several years, immunotherapy – therapies that enlist and strengthen the power of a patient’s immune system to attack tumors - has emerged as a new tool for fighting cancer. In August 2017, one such treatment approach, called Chimeric Antigen Receptor or CAR T-cell Therapy,...

Duration:00:11:00

Unclog the Arteries: Treatment Options for Arterial Disease

6/7/2017
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Host: Barnett Mennen, MD Guest: Grace Wang, MD, FACS Unclogging patient arteries is a key step to preventing stroke in patients with arterial disease. Whether it be preventing the operative stage, or surgery itself, advances in treatment at Penn Medicine are seeking to lessen the effects of arterial disease. Host Dr. Barry Mennen welcomes Dr. Grace Wang, vascular surgeon and Director of the Vascular Laboratory at the Hospital of the University of Pennsylvania. Dr. Wang highlights the...

Duration:00:14:59

Pancreatic Cancer: Associated Signs, Symptoms, Risk Factors and Treatment Approaches

5/23/2017
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Host: Jennifer Caudle, DO Guest: Major Kenneth Lee, IV, MD, PhD Though a relatively rare disease, pancreatic cancer remains at the forefront of clinical discussion due to its highly aggressive nature. Dr. Major Kenneth Lee, Assistant Professor of Surgery at Penn Medicine, estimates that pancreatic cancer will become the number 2 cause of cancer death by the year 2020. This projected rise in mortality is largely due to the need for better advancement in treatment options. Join host Dr....

Duration:00:17:59

Hepatitis C Virus (HCV): Current Screening Guidelines and Treatment Approaches

5/3/2017
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Host: Jennifer Caudle, DO Guest: Vincent Lo Re, MD, MSCE In 2014, the CDC estimated a total of 2,194 cases of acute hepatitis across 40 states and estimates that 2.7-3.9 million people in the United States have chronic hepatitis C. Of every 100 persons affected by the disease, 75 to 85 will go on to develop chronic infection, 60 to 70 will go on to develop chronic liver disease, 5 to 20 will go on to develop cirrhosis over a period of 20–30 years, and 1 to 5 will die from the...

Duration:00:17:00

Neck and Back Pain: When Should You Refer Your Patients to a Neurosurgeon?

2/13/2017
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Host: Matt Birnholz, MD Guest: Patrick J. Connolly, MD Back and neck pain is extremely common, with 80-90% of people experiencing some pain within their lifetime. About 90% of cases resolve within six weeks, but for those patients whose pain persists, questions arise as to who should be referred next for further consultation. While patients often see a spine specialist at first, the care journey sometimes leads to a neurosurgeon or orthopaedic spine surgeon. Can this pathway from primary...

Duration:00:11:59

Hot Topics in Counseling Patients Who are Trying to Conceive

2/6/2017
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Host: Matt Birnholz, MD Guest: Robert H. Debbs, DO Joining Dr. Matt Birnholz to discuss counseling methods for patients who are trying to conceive is Dr. Robert Debbs, Director of the Pennsylvania Hospital Maternal Fetal Medicine Network in New Jersey and Clinical Professor of Obstetrics and Gynecology at Penn Medicine. Dr. Debbs will discuss pre-conceptual counseling on a range of topics such as obesity, congenital heart disease, depression, and conceiving after a miscarriage.

Duration:00:14:00

Hot Topics in Breast Cancer Innovations

2/6/2017
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Host: Matt Birnholz, MD Guest: Ari Brooks, MD Guest: Brian Englander, MD Host Dr. Matt Birnholz is joined by Dr. Ari Brooks, Director of Endocrine and Oncology Surgery and Director of the Integrated Breast Center at Pennsylvania Hospital, and Dr. Brian Englander, Clinical Assistant Professor and Chair of the Department of Radiology at Pennsylvania Hospital. Drs. Brooks and Englander discuss the hot topics within breast cancer innovations. They touch upon the increase in involvement of...

Duration:00:19:30

A Thoracic Surgeon's Viewpoint on Screening, Diagnosis and Treatment of a Lung Cancer Patient

2/2/2017
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Host: Matt Birnholz, MD Guest: Taine Pechet, MD Dr. Taine Pechet, chief of surgery at Penn Presbyterian Medical Center and associate professor of clinical surgery at Penn Medicine joins host Dr. Matt Birnholz to discuss his thoughts on who should be regularly screen for lung cancer and the various diagnostic techniques from his perspective as a thoracic surgeon. Dr. Pechet also discusses the surgical outcomes for these patient and his thoughts on what is on the horizon for the lung...

Duration:00:15:00

Full Spectrum of Breast Reconstruction Surgeries: From Cosmetic to Breast Cancer Diagnosis

2/2/2017
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Host: Matt Birnholz, MD Guest: Paris D. Butler, MD, MPH Host Dr. Matt Birnholz welcomes Dr. Paris D. Butler, who will be discussing breast reduction surgery for women who suffer from chronic back pain and breast cancer patients undergoing reconstructive surgery following a diagnosis. Dr. Butler will go into detail about the pros and cons of taking an immediate versus a delayed reconstruction approach and the various techniques associated.

Duration:00:13:30

Curing Blindness: How Researchers are Utilizing Gene Therapy

1/5/2017
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Host: Shira Johnson, MD Guest: Jean Bennett, MD, PhD There are 39 million people worldwide who are in total blindness and another 246 million with very low vision. The most frequent forms of visual impairment are caused by problems that can be corrected. Dr. Shira Johnson welcomes Dr. Jean Bennett, Professor of Ophthalmology and Cell and Developmental Biology at the University of Pennsylvania and researcher at the Children’s Hospital of Philadelphia. Dr. Bennett discusses her innovative...

Duration:00:18:30

Cranial Base Disorders: Etiologies, Surgical Approaches, and Research Innovations

10/10/2016
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Host: Matt Birnholz, MD Guest: John Y.K. Lee, MD Guest: Jason G. Newman, MD, FACS Joining Dr. Matt Birnholz to discuss innovative surgical approaches to cranial base disorders are Doctors John Y. K. Lee and Jason G. Newman. Dr. Lee is Medical Director of the Gamma Knife Center and Associate Professor of Neurosurgery and Otorhinolaryngology-Head and Neck Surgery at the Pennsylvania Hospital. Dr. Newman is Associate Professor of Otorhinolaryngology-Head and Neck Surgery at the Center for...

Duration:00:17:29

Time is Brain: Diagnosing and Treating Stroke in the Golden Window

8/8/2016
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Host: Jennifer Caudle, DO Guest: Michael Mullen, MD Every second counts for stroke patients. During a stroke, two-million brain cells die every minute, making the urgent administration of therapies and treatment vital to ensure a positive outcome. Host Dr. Jennifer Caudle is joined by Dr. Michael Mullen, Assistant Professor of Neurology at Penn Medicine. They discuss the clinical hallmarks and priority treatment consideration for stroke.

Duration:00:12:59

Innovations in Diagnosis and Treatment of Multiple Sclerosis

8/1/2016
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Host: Jennifer Caudle, DO Guest: Joseph Berger, MD, FACP, FAAN, FANA Multiple sclerosis is a notoriously difficult disease to diagnose early on. With no singular confirmatory tests yet available, physicians often become reluctant to identify MS in their patients, leading to years of diagnostic and treatment uncertainty. But new innovations are helping doctors establish earlier diagnoses and start more targeted treatments for MS patients. Dr. Jennifer Caudle welcomes Dr. Joseph Berger,...

Duration:00:23:29

4 Latest Advances in Epilepsy Treatment at Penn

7/18/2016
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Host: Jennifer Caudle, DO Guest: Kathryn Davis, MD, MTR Guest: Timothy Lucas, MD, PhD According to the epilepsy foundation, epilepsy is the 4th most common neurological problem in the U.S. – only migraine, stroke and Alzheimer’s disease occur more frequently. The average incidence of epilepsy each year in the U. S is estimated at 150,000, or 48 for every 100,000 people. Host Dr. Jennifer Caudle talks with Doctors Kathryn Davis and Timothy Lucas about advances in treatment for epilepsy at...

Duration:00:16:30

Groundbreaking Child Bilateral Hand Transplant

7/4/2016
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Host: Shira Johnson, MD For the first time, Penn Medicine surgeons were able to complete a bilateral hand transplant on a child. The surgical team successfully transplanted donor hands and forearms onto 8-year-old Zion Harvey who, several years earlier, had undergone amputation of his hands and feet and a kidney transplant following a serious infection. Host Dr. Shira Johnson sits down with Dr. Scott Levin, who led the surgical team and is Chairman of the Department of Orthopaedic Surgery...

Duration:00:25:00