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UpToDate® is the premier evidence-based clinical decision support resource, trusted worldwide by healthcare practitioners to help them make the right decisions at the point of care. It is proven to change the way clinicians practice medicine, and is the only resource of its kind associated with improved outcomes. Support for UpToDate Talk is provided by UpToDate, Wolters Kluwer. UpToDate is entirely funded by the subscriptions of its users and does not accept advertising or funding unrelated to subscriptions. The opinions in such podcasts are entirely those of the discussants, and these discussants are authors and editors for UpToDate. View UpToDate’s conflict of interest policy: http://www.uptodate.com/home/conflict-interest-policy.

UpToDate® is the premier evidence-based clinical decision support resource, trusted worldwide by healthcare practitioners to help them make the right decisions at the point of care. It is proven to change the way clinicians practice medicine, and is the only resource of its kind associated with improved outcomes. Support for UpToDate Talk is provided by UpToDate, Wolters Kluwer. UpToDate is entirely funded by the subscriptions of its users and does not accept advertising or funding unrelated to subscriptions. The opinions in such podcasts are entirely those of the discussants, and these discussants are authors and editors for UpToDate. View UpToDate’s conflict of interest policy: http://www.uptodate.com/home/conflict-interest-policy.
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United States

Description:

UpToDate® is the premier evidence-based clinical decision support resource, trusted worldwide by healthcare practitioners to help them make the right decisions at the point of care. It is proven to change the way clinicians practice medicine, and is the only resource of its kind associated with improved outcomes. Support for UpToDate Talk is provided by UpToDate, Wolters Kluwer. UpToDate is entirely funded by the subscriptions of its users and does not accept advertising or funding unrelated to subscriptions. The opinions in such podcasts are entirely those of the discussants, and these discussants are authors and editors for UpToDate. View UpToDate’s conflict of interest policy: http://www.uptodate.com/home/conflict-interest-policy.

Language:

English


Episodes

Peanut oral immunotherapy in children and young adults

5/30/2018
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This episode features Dr. Robert Wood discussing the results of a trial of oral immunotherapy with a manufactured peanut protein product for peanut desensitization, and its potential role in clinical practice. Dr. Nancy Sokol hosts. Dr. Wood is Professor of Pediatrics and Director of Pediatric Allergy and Immunology at the Johns Hopkins University School of Medicine and Professor of International Health at the Johns Hopkins Bloomberg School of Public Health. He is Editor-in-Chief of the...

Duration:00:17:41

Digoxin levels and mortality in patients with atrial fibrillation

5/23/2018
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Dr. Leonard Ganz discusses pharmacologic rate control of atrial fibrillation (AF) and findings of a recent study published in the Journal of the American College of Cardiology regarding the use of digoxin and mortality in patients with AF. Dr. Nancy Sokol hosts. Dr. Ganz is a clinical cardiologist and Director of Cardiac Electrophysiology at the Heritage Valley Health System, in Western Pennsylvania, and Section Editor of the cardiac arrhythmias section in UpToDate. Reference: Lopes RD,...

Duration:00:15:05

PERC criteria for ruling out pulmonary embolism

5/15/2018
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Dr. Christopher Kabrhel discusses the PERC rule for evaluating patients with suspected pulmonary embolism and a trial exploring the effects of implementing the PERC rule in emergency departments in France, published in JAMA in February 2018. Dr. Nancy Sokol hosts. Dr. Kabrhel is Associate Professor at Harvard Medical School, an Emergency Medicine physician at Massachusetts General Hospital, and author of several topics on pulmonary embolism for UpToDate. Reference: Freund Y, Cachanado M,...

Duration:00:20:45

Under-recognition of fetal alcohol spectrum disorders

5/8/2018
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This episode features Dr. Carol Weitzman discussing a recent study showing a higher incidence of fetal alcohol spectrum disorders in children than previously thought, as well as methods to raise awareness and improve detection. Dr. April Eichler hosts. Dr. Weitzman is Professor of Pediatrics and Director of the Developmental-Behavioral Pediatrics Program at the Yale School of Medicine. She is an author in the Pediatrics specialty at UpToDate. Reference: May PA, Chambers CD, Kalberg WO, et...

Duration:00:13:57

Time window for mechanical thrombectomy after acute ischemic stroke

5/1/2018
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This episode features Dr. Jose Biller discussing two recent studies showing that intra-arterial mechanical thrombectomy improves neurologic outcomes when performed up to 24 hours after symptom onset for selected patients with ischemic stroke. Dr. April Eichler hosts. Dr. Biller is a Professor of Neurology and Neurological Surgery and Chairman of the Department of Neurology at the Loyola University Chicago Stritch School of Medicine. He is Section Editor in the Neurology specialty at...

Duration:00:15:32

Indications for surgery after a first episode of acute diverticulitis

4/24/2018
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Dr. John Pemberton discusses a cohort study of patients with acute diverticulitis followed for 4 years for recurrence rates and need for surgery following the initial episode, published in Diseases of the Colon & Rectum in March 2018. Dr. Nancy Sokol hosts. Dr. Pemberton is Professor of Surgery at the Mayo Clinic and Mayo Medical School, and authors several topics on diverticular disease for UpToDate. Reference: El-Sayed C, Radley S, Mytton J, et al. Risk of Recurrent Disease and Surgery...

Duration:00:11:25

Catheter ablation for atrial fibrillation with heart failure

4/17/2018
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Dr. Brian Olshansky discusses a paper in the February 2018 New England Journal of Medicine regarding a trial of catheter ablation for atrial fibrillation with heart failure. Dr. Nancy Sokol hosts. Dr. Olshansky is Professor Emeritus of Internal Medicine at the University of Iowa, Adjunct Professor of Medicine at Des Moines University, and Section Editor for UpToDate cardiology topics. Reference: Marrouche NF, Brachmann J, Andresen D, et al. Catheter Ablation for Atrial Fibrillation with...

Duration:00:15:55

Vaccination to prevent herpes zoster

4/10/2018
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This episode features Dr. Kenneth Schmader discussing new guidelines from the Advisory Committee on Immunization Practices regarding the herpes zoster vaccines. Dr. Sadhna Vora hosts. Dr. Schmader is a Professor of Medicine and Chief of the Division of Geriatrics at Duke University. He is Section Editor in Primary Care and Editor-in-Chief of the Geriatrics specialty at UpToDate. Reference: Dooling KL, Guo A, Patel M, et al. Recommendations of the Advisory Committee on Immunization Practices...

Duration:00:13:52

Partially closed loop glucose monitoring in children and adolescents with type 1 diabetes

4/3/2018
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This episode features Dr. Joseph Wolfsdorf discussing advances in devices to manage children and adolescents with type 1 diabetes. Dr. Sadhna Vora hosts. Dr. Wolfsdorf is a Professor of Pediatrics at Harvard Medical School and Director of the Diabetes Program at Boston Children's Hospital. He is also Section Editor in Pediatric Endocrinology at UpToDate. Reference: Abraham MB, Nicholas JA, Smith GJ, et al. Reduction in Hypoglycemia with the Predictive Low-Glucose Management System: A...

Duration:00:14:11

Third dose of MMR vaccine for prevention of mumps in an outbreak setting

3/27/2018
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This episode features Dr. Sheldon Kaplan discussing the use of a third dose of the MMR vaccine for the prevention of mumps in an outbreak setting. Dr. Jennifer Mitty hosts. Dr. Kaplan is Professor of Pediatrics and head of the Pediatric Infectious Disease section at Baylor College of Medicine, and he is Chief of the Infectious Disease service and head of the Department of Pediatric Medicine at Texas Children's Hospital in Houston. References: Marin M, Marlow M, Moore KL, et al....

Duration:00:15:54

Naltrexone versus buprenorphine for opioid use disorder

3/20/2018
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This episode features Dr. Andrew Saxon discussing treatments for opioid use disorder. Dr. Jennifer Mitty hosts. Dr. Saxon is a Professor in the Department of Psychiatry and Behavioral Sciences at the University of Washington in Seattle, and he is Chair of the American Psychiatric Association's Council on Addiction Psychiatry. References: Lee JD, Nunes EV Jr, Novo P, et al. Comparative effectiveness of extended-release naltrexone versus buprenorphine-naloxone for opioid relapse prevention...

Duration:00:16:25

Monoclonal antibodies to prevent migraine; Oral fecal microbiota transplant for C. diff infection

3/6/2018
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Today’s episode of UpToDate Talk features Dr. Jerry Swanson discussing novel monoclonal antibody therapies to prevent migraines, and Dr. Ciarán Kelly discussing oral fecal microbiota transplantation for the treatment of C. difficile infection. The second segment begins at 14:58. Dr. Nancy Sokol hosts.

Duration:00:29:32

Edoxaban vs low molecular weight heparin in cancer-related VTE; New treatment for cystic fibrosis

2/20/2018
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Today’s UpToDate Talk episode features discussions related to three papers published in the New England Journal of Medicine. Dr. Jess Mandel discusses anticoagulation options for cancer-associated venous thromboembolism, and Dr. George Mallory discusses two studies of tezacaftor-ivacaftor in patients with cystic fibrosis. Segment two begins at 11:32. Dr. Helen Hollingsworth hosts.

Duration:00:25:37

Management of suicide risk in children and adolescents; Increasing prevalence of syphilis in the US

2/6/2018
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Today’s episode of UpToDate Talk features Dr. Gregory Simon discussing the management of suicide risk in children and adolescents, and Dr. Khalil Ghanem discussing the increasing prevalence of syphilis in the United States. The second segment begins at 18:10. Dr. Nancy Sokol hosts.

Duration:00:38:23

Frequency for dosing of oral iron; Risk of late recurrence after endocrine therapy for breast cancer

1/23/2018
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In this episode of UpToDate Talk, Dr. Stanley Schrier joins us to discuss an article from Lancet Haematology on a new paradigm for the dosing of oral iron, and Dr. Dan Hayes discusses his meta-analysis from the New England Journal of Medicine on the risk of late recurrence after adjuvant endocrine therapy for breast cancer. Dr. Jennifer Tirnauer hosts. Figure on hepcidin in UpToDate: https://www.uptodate.com/contents/image?imageKey=HEME%2F105245

Duration:00:31:04

Revised recommendations for endoscopy in dyspepsia; New hypertension criteria in ACC/AHA guidelines

1/9/2018
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This edition of UpToDate Talk features Dr. Nicholas Talley, who joins us to discuss the evaluation and management of dyspepsia in adults, and Dr. William White, who discusses the new ACC/AHA guidelines for the evaluation and management of high blood pressure in adults. Dr. April Eichler hosts.

Duration:00:37:54

PFO closure for prevention of recurrent stroke; Cost-effectiveness of triple therapy in RA

12/13/2017
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This episode of UpToDate Talk begins with Dr. Scott Kasner, who outlines three recent NEJM studies investigating the effects of PFO device closure on recurrent stroke risk. The second segment features Dr. James O’Dell, discussing the cost effectiveness of triple therapy in the treatment of rheumatoid arthritis. Dr. Helen Hollingsworth hosts.

Duration:00:28:05

Investigational gene editing in human embryos to prevent disease; Tests for diagnosis of influenza

11/29/2017
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This episode features Dr. Benjamin Raby discussing a recent paper on correcting a pathogenic gene mutation in human embryos, and Dr. Martin Hirsch discussing testing for diagnosing influenza. Dr. Nancy Sokol hosts.

Duration:00:30:49

Prevention of HIV in high risk adolescents; ICDs for treatment of nonischemic cardiomyopathy

11/15/2017
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This episode features Dr. Kenneth Mayer, discussing use of pre-exposure HIV prophylaxis for high-risk adolescents, and Dr. Samuel Lévy, discussing use of an implantable cardioverter defibrillator for the primary prevention of sudden death in patients with nonischemic cardiomyopathy. Dr. Nancy Sokol hosts.

Duration:00:30:36

Zika virus prenatal infection and birth outcome; Evaluation for occult cancer in unprovoked VTE

11/1/2017
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This episode features Dr. Karin Nielsen discussing maternal Zika virus and potential factors associated with birth outcomes, and Dr. Jess Mandel discussing screening for occult cancer in patients with unprovoked venous thromboembolism. Dr. Jennifer Mitty hosts.

Duration:00:23:01