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This Week in Microbiology

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Episodes

176: Elio has lots of colanic acid

5/17/2018
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Vincent, Michael and Elio note the passing of Stanley Falkow, give E. coli an archaeal membrane, and how the microbiome can make worms live longer. Hosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter. Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a patron of TWiM. Links for this episode Fecal transplants in the good old days (STC) Stanley Falkow, 84 Loss of an old army buddy...

Duration:00:59:47

175: Neomycin is antiviral

5/2/2018
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The TWiM team notes the passing of Allan Campbell, and explains how aminoglycoside antibiotics like neomycin enhance host resistance to viral infection. Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson. Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a patron of TWiM. Links for this episode Happy Birthday, Elio! (STC) Allan Campbell, 88 (Stanford News) Life in Science by Allan...

Duration:01:03:05

174: A Gathering Typhoid Storm

4/19/2018
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The TWiMsters explain why untreatable typhoid fever might be on the way, and the evolution of fungal virulence in tropical frogs. Hosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter. Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a patron of TWiM. Links for this episode Extensively drug resistant Salmonella typhi (mBio) A Gathering Storm (mBio) Typhoid vaccine recommendations...

Duration:01:02:24

173: Gee whiz in style

3/30/2018
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The Masters of the Microbiological Universe discuss the humongouest fungus, and a commensal bacterium that protects against skin neoplasia. Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter. Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a patron of TWiM. Links for this episode Fertile prototaxites (Proc Royal Soc B) The humongousest fungus (STC) Commensal...

Duration:00:58:33

Unfolding relaxases and soil malacidins - TWiM 172

3/15/2018
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The TWiMmers discuss culture-independent discovery of malacidin antibiotics, and unfolding of relaxase during bacterial conjugation. Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter. Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a patron of TWiM. Links for this episode Malacidins from soils (Nat Micro) Excellent antibiotic resistance threat report (CDC,...

Duration:01:13:31

171: If you give a bee a fungus

2/22/2018
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The TWiM team explores a stingless bee that requires a fungal steroid to pupate, and colonic biofilms containing tumorigenic bacteria in patients with colorectal polyps. Hosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter. Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a patron of TWiM. Links for this episode Bee larvae require fungal steroid to pupate (Sci Rep) Biofilm refuge for...

Duration:01:00:32

TWiM #170: Rats, lice, and nanoparticles

2/7/2018
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The TWiM team reveals that spread of plague was likely by human ectoparasites, not rats, and deconstruct a durable, broadly protective protein nanoparticle influenza virus vaccine. Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter. Become a patron of TWiM. Links for this episode Ectoparasites and plague (PNAS) SIR model for spread of disease (MAA) Protein nanoparticle flu vaccines (Nat Commun) Food washing (USDA) Image credit Letters read on TWiM...

Duration:00:55:53

169: Breatharian Bacteria

1/23/2018
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The cast of TWiM reveals how uropathogenic E. coli use a copper-binding protein to treat copper as a nutrient or a toxin, and Antarctic soil bacteria that survive on trace atmospheric gases. Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter. Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a patron of TWiM. Links for this episode Copper import in E. coli (Nat Chem...

Duration:01:02:27

TWiM #168: The lesser of two weevils

1/4/2018
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Dickson joins the TWiM team to discuss the nasal microbiota of dairy farmers, and attenuation of bacterial virulence by quorum sensing in the maize weevil. Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson. Guest: Dickson Despommier Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a patron of TWiM. Links for this episode: Nasal microbiota of dairy farmers (PLoS One) Measuring...

Duration:01:16:34

TWiM #167: I have one word for you: Flink

12/21/2017
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How pandemic influenza viruses suppress immunogenic cell death, and 3D printing of bacteria into functional materials.

Duration:00:52:39

TWiM #166: Dark fermentation

12/7/2017
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Vincent and Elio discuss the reason for poor efficacy of one of the influenza virus vaccines, and using a hyperthermophilic anaerobe to produce hydrogen from fruit and vegetable wastes in seawater. Hosts: Vincent Racaniello and Elio Schaechter. Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the ASM Podcast app. Become a patron of TWiM. Links for this episode Glycosylation site on influenza H3N2 viruses (PNAS) Biohydrogen...

Duration:00:51:12

TWiM #165: Pumping Copper

11/30/2017
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The TWiM team discusses the use of copper on exercise weights to reduce bacterial burden, and the mechanism of antigenic variation by which a fungus that causes severe pneumonia escapes the immune system. Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt, and Michele Swanson Links for this episode: Reducing bacteriaon exercise weights with copper (Am J Inf Contr)Antigenic variationinPneumocystis jirovecii(mBio)Letters read on TWiM 165

Duration:01:03:18

TWiM #164: Indiana Quorum

11/16/2017
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From Indiana University, Vincent speaks with Ankur, Julia, and Xindan about their careers and their work on horizontal gene transfer, quorum sensing, and chromosome organization in bacteria. Guests: Ankur Dalia, Julia Van Kessel, and Xindan Wang Watch the video version! https://www.youtube.com/watch?v=ifGCe-qfnA0 Become a patron of TWiM. Links for this episode: Dalialaboratory Van Kessellaboratory WanglaboratoryIndiana UDept of BiologyVibrio DNA uptake and chitin(Environ...

Duration:00:59:09

TWiM #163: Saliva and sptR/S

11/2/2017
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This episode is all about saliva: how certain bacteria survive in it, and how swallowing saliva might cause intestinal inflammation. Links for this episode: Genes for theStreptococcus pyogenesfitness in human saliva (mSphere)Swallowed bacteriadrive colonic inflammation (Science)Intestinal inflammationinduced by oral bacteria (Science)Humanoral microbiome(J Bact) T cell subsets(Nat Rev Imm)Image credit

Duration:01:06:16

TWiM #162: Intracellular bacteria with flagella

10/12/2017
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The TWiM hosts and associated microbiomes review a fungus destroying salamanders in Europe, and genes for flagella in intracellular bacteria. Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter. Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a patron of TWiM. Links for this episode Fungus killing fire salamanders (Nature) Chlamydia with flagella (ISME J) Flagellar...

Duration:00:52:41

TWiM #161: Eros, a bacterial aphrodisiac

9/21/2017
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From the TWiM team, a discussion of Hurricane Harvey microbiology, and a bacterial enzyme that induces eukaryotic mating. Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter. Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a patron of TWiM. Links for this episode Tainted Houston floodwaters (NYTimes) Peter Hotez on TWiP 29 FAQ: Microbiology of Built Environments,...

Duration:00:55:55

TWiM #160: On the road to virus

9/8/2017
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The TWiM team provides an update on Zika virus, and reveals a plasmid on the road to becoming a virus.

Duration:01:07:03

TWiM 159: Immunophage synergy

8/31/2017
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The TWiM team pays a tribute to Chris Condayan, and investigates the synergy between virus and the innate immune system for clearing bacterial pneumonia by phage therapy.

Duration:01:00:35

TWiM #158: The bottom line

8/10/2017
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The TWiM team considers a report on prokaryotic viral DNA in mammalian brain, and how diarrhea is beneficial, by clearing enteric pathogens. Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson and Elio Schaechter. Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a patron of TWiM. Links for this episode Prokaryotic viral sequence in the brain (PNAS) Diarrhea clears enteric pathogens...

Duration:01:05:00

TWiM #157: Back to the ancestor

7/27/2017
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The TWiMbionts explore the role of bacteria in the genesis of moonmilk, and how ancient host proteins can be used to engineer resistance to virus infection. Hosts: Vincent Racaniello, Michele Swanson and Elio Schaechter. Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Become a patron of TWiM. Links for this episode Role of Streptomyces in moonmilk (bioRxiv) TWiM 51: Cave science with Hazel...

Duration:00:56:42

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