Big Picture Science

Heredity was once thought to be straightforward. Genes were passed in an immutable path from parents to you, and you were stuck – or blessed – with what you got. DNA didn’t change. But now we know that’s not true. Epigenetic factors, such as your environment and your lifestyle, control how your genes are expressed. Meanwhile, the powerful tool CRISPR allows us to tinker with the genes themselves. DNA is no longer destiny. Hear the results from the NASA twin study and what happened to...

Okay you animals, line up: stoned sloths, playful pandas, baleful bovines, and vile vultures. We’ve got you guys pegged, thanks to central casting. Or do we? Our often simplistic view of animals ignores their remarkable adaptive abilities. Stumbly sloths are in fact remarkably agile and a vulture’s tricks for thermoregulation can’t be found in an outdoors store. Our ignorance about some animals can even lead to their suffering and to seemingly intractable problems. The South American...

(Repeat) We’re hearing about harassment of, and barriers to, women seeking careers in politics and entertainment. But what about science? Science is supposed to be uniquely merit-based and objective. And yet the data say otherwise. A new study reveals widespread harassment of women of color in space science. We look at the role that a hostile work environment plays in keeping women from pursuing scientific careers. While more women than ever are holding jobs in science, the percentage in...

Do we still need doctors? There are umpteen alternative sources of medical advice, including endless and heartfelt health tips from people without medical degrees. Frankly, self-diagnosis with a health app is easier and cheaper than a trip to a clinic. Since we’re urged to be our own health advocate and seek second opinions, why not ask Alexa or consult with a celebrity about what ails us? Find out if you can trust these alternative medical advice platforms. Plus, lessons from an AIDS...

(Repeat) The biotech tool CRISPR lets us do more than shuffle genes. Researchers have embedded an animated GIF into a living organism’s DNA, proving that the molecule is a great repository for information. This has encouraged speculation that DNA could be used by aliens to send messages. Meanwhile, nature has seized on this powerful storage system in surprising ways. Scientists have learned that the 98% of our genome – once dismissed as “junk” – contains valuable genetic treasure. Find out...

(repeat) Changed your computer password recently? We all try to stay one step ahead of the hackers, but the fear factor is increasing. The risks can range from stolen social security numbers to sabotaging a national power grid. Sixty years ago, when hacking meant nosing around the telephone network, it seemed innocent enough. And not all modern hacking has criminal intent. Today, there are biohackers who experiment with implanted electronic devices to improve themselves, and geoengineers...

(repeat) Long before cyber criminals were stealing ATM passwords, phone phreaks were tapping into the telephone system. Their motivation was not monetary, but the thrill of defeating a complex, invisible network. Today “hacking” can apply to cyberwarfare, biological tinkering, or even geoengineering. Often it has negative connotations, but the original definition of “hacking” was something else. In this first of two episodes on hacking, we look at the original practitioners – the teenagers...

The seas are rising. It’s no longer a rarity to see kayakers paddling through downtown Miami. By century’s end, the oceans could be anywhere from 2 to 6 feet higher, threatening millions of people and property. But humans once knew how to adapt to rising waters. As high water threatens to drown our cities, can we learn do it again. Hear stories of threatened land: submerged Florida suburbs, the original sunken city (Venice), and the U.S. East Coast, where anthropologists rush to catalogue...

(Repeat) Celebrations are in order for the physicists who won the 2017 Nobel Prize, for the detection of gravitational waves. But the road to Stockholm was not easy. Unfolding over a century, it went from doubtful theory to daring experiments and even disrepute. 100 years is a major lag between a theory and its confirmation, and new ideas in physics may take even longer to prove. Why it may be your great, great grandchildren who witness the confirmation of string theory. Plus, the exciting...

There’s evidence for a subsurface lake on Mars, and scientists are excitedly using the “h” word. Could the Red Planet be habitable, not billions of years ago, but today? While we wait – impatiently – for a confirmation of this result, we review the recipe for habitable alien worlds. For example, the moon Titan has liquid lakes on its surface. Could they be filled with Titanites? Dive into a possible briny, underground lake on Mars … protect yourself from the methane-drenched rain on a moon...

Looking to boost your brainpower? Luckily, there are products promising to help. Smart drugs, neurofeedback exercises, and brain-training video games all promise to improve your gray matter’s performance. But it’s uncertain whether these products really work. Regulatory agencies have come down hard on some popular brain training companies for false advertising. But other brain games have shown benefits in clinical trials. And could we skip the brain workout altogether and pop a genius pill...

(Repeat) Astronauts are made of the “right stuff,” but what about their spacesuits? NASA’s pressurized and helmeted onesies are remarkable, but they need updating if we’re to boldly go into deep space. Suiting up on Mars requires more manual flexibility, for example. Find out what innovative materials might be used to reboot the suit. Meanwhile, strange new materials are in the pipeline for use on terra firma: spider silk is kicking off the development of biological materials that are...

DNA is the gold standard of identification. Except when it’s not. In rare cases when a person has two complete sets of DNA, that person’s identity may be up in the air. Meanwhile, DNA ancestry tests are proving frustratingly vague: dishing up generalities about where you came from rather than anything specific. And decoding a genome is still relatively expensive and time-consuming. So, while we refine our ability to work with DNA, the search is on for a quick and easy biomarker test to tell...

ENCORE Water is essential for life – that we know. But the honeycomb lattice that forms when you chill it to zero degrees Celsius is also inexorably intertwined with life. Ice is more than a repository for water that would otherwise raise sea levels. It’s part of Earth’s cooling system, a barrier preventing decaying organic matter from releasing methane gas, and a vault entombing ancient bacteria and other microbes. From the Arctic to the Antarctic, global ice is disappearing. Find out...

ENCORE It’s not just tin cans and newspapers. One man says that, from a technical standpoint, everything can be recycled – cigarette butts, yoga mats, dirty diapers. Even radioactive waste. You name it, we can recycle it. But we choose not to. Find out why we don’t, and how we could do more. Plus, a solar-powered device that pulls water from the air – even desert air. And, something upon which life depends that seems dirt cheap, but can’t be replenished: soil. What happens when we pave...

ENCORE It’s one of the most bizarre biological experiments ever. In the 18th century, a scientist fitted a pair of tailor-made briefs on a male frog to determine the animal’s contribution to reproduction. The process of gestation was a mystery and scientists had some odd-ball theories. Today, a 5th grader can tell you how babies are made, but we still don’t know exactly what life is. In our quest to understand, we’re still at the frogs’ pants stage. Find out why conception took centuries...

Dinosaurs are once again stomping and snorting their way across the screen of your local movie theater. But these beefy beasts stole the show long before CGI brought them back in the Jurassic Park blockbusters. Dinosaurs had global dominance for the better part of 165 million years. Compare that with a measly 56 million years of primate activity. We bow to our evolutionary overlords in this episode. Our conversation about these thunderous lizards roams freely as we talk with the...

ENCORE Get ready for compassionate computers that feel your pain, share your joy, and generally get where you’re coming from. Computers that can tell by your voice whether you’re pumped up or feeling down, or sense changes in heart rate, skin, or muscle tension to determine your mood. Empathetic electronics that you can relate to. But wait a minute – we don’t always relate to other humans. Our behavior can be impulsive and even self-sabotaging – our emotions are often conflicted and...

The Earth is not round. Technically, it’s an oblate spheroid. But for some people, the first statement is not even approximately correct. Flat Earthers believe that our planet resembles – not a slightly squashed grapefruit – but a thick pancake. A journalist who covered a Flat Earth convention describes the rationale behind this ever-more popular belief. So how do you establish science truth? We look at the difference between a truly scientific examination of extraordinary claims and...

Pluto, we hardly knew ye. Well, not anymore! Until recently, Pluto and Mars were respectively the least-known and best-known planet-sized bodies in our Solar System. Thanks to the New Horizons spacecraft, our picture of Pluto has changed from a featureless dot to a place where we can name the geologic features. And with rovers and orbiters surveying the red planet, we now know much more about Mars than our parents ever did. Examining our planetary backyard has provided insight into the...