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neuroscience... served fresh!

neuroscience... served fresh!
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Location:

United States

Description:

neuroscience... served fresh!

Twitter:

@GrossBrains

Language:

English


Episodes

Recovery in Severe TBI

11/1/2019
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How good are we at predicting outcome in severe TBI? Do all patients do bad, or are there some that recover? On this episode Karl dives into the data to give us an update on what the data supports. Literature Referenced: What early predictions do we make? Barlow, P., Teasdale, G. (1986). Prediction of Outcome and the Management of Severe Head Injuries: The Attitudes of Neurosurgeons Neurosurgery 19(6), 989-991. https://dx.doi.org/10.1227/00006123-198612000-00014 How good are we at...

Duration:00:47:39

Ketamine in TBIs

10/6/2019
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Is ketamine safe to use in TBI patients (or anyone with increased ICP)? The usual answer is “heck no!”, but where does this come from, and is it true? This week, Karl and I talk about the origin of this believe and the evidence behind the safety of ketamine in TBIs (and how it might actually improve outcome...) Literature Referenced: Original Lancet letter that started everything. Four cases of increased ICP after ketamine administration. Evans, J., Rosen, M., Weeks, R., Wise, C. (1971)....

Duration:00:37:11

Does dexamethasone worsen mortality in GBM?

9/20/2019
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Really? Decadron can worsen mortality in GBMs? This week Karl and I go over the evidence showing that steroids might not be the best thing for GBM patients. Specifically, it looks like dexamethasone might interfere with the effectiveness of chemo and radiation, leading to worse outcomes. Literature Referenced: Opinion paper that summarizes the argument against using Decadron in GBM patients: Wong, E., Swanson, K. (2019). Dexamethasone—Friend or Foe for Patients With Glioblastoma? JAMA...

Duration:00:35:48

Trailer episode

9/12/2019
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Want a taste of what's to come? The first full episode will be released shortly! Here's something to tide you over...

Duration:00:02:18