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Genetics Unzipped

Science Podcasts

From Mendel's peas to personal genome sequencing, Genetics Unzipped brings you stories from the world of genes, genomes and DNA. In association with The Genetics Society.

From Mendel's peas to personal genome sequencing, Genetics Unzipped brings you stories from the world of genes, genomes and DNA. In association with The Genetics Society.

Location:

United Kingdom

Description:

From Mendel's peas to personal genome sequencing, Genetics Unzipped brings you stories from the world of genes, genomes and DNA. In association with The Genetics Society.

Language:

English


Episodes

S3.24 Best bits of 2020

11/19/2020
We look back over our favourite bits from the podcast over the year, from dark family secrets revealed by genetic testing to the secret scientific history of bird poop. Jack Nunn - hidden family secrets revealed Listen to the full episode The bird poop boom Listen to the full episode Ewen’s angry birds Listen to the full episode Darwin’s finches Listen to the full episode Sarah Tishkoff Listen to the full episode Full show notes, transcript, music credits and references online at...

Duration:00:32:07

Genetics Shambles 10: In conversation with Prof Aoife McLysaght

11/12/2020
Robin Ince sits down for a chat with Aoife McLysaght, Professor in the Molecular Evolution Laboratory of the Smurfit Institute of Genetics, University of Dublin, Trinity College and one of the 2018 Royal Institution Christmas Lecturers. This series of Genetics Shambles is presented in association with The Genetics Society and The Milner Centre for Evolution. Find out more at CosmicShambles.com. To view previous episodes in the Genetics Shambles series head to Cosmicshambles.com Follow us...

Duration:00:50:15

S3.23 Heat, Stick, Duplicate, Repeat: The Story Of The Polymerase Chain Reaction (PCR)

11/5/2020
Anyone who has worked with DNA in the laboratory is undoubtedly familiar with the polymerase chain reaction - PCR, as it’s usually known. Invented in 1985, PCR is an indispensable molecular biology tool that can replicate any stretch of DNA, copying it billions of times in a matter of hours, providing enough DNA to use in sequencing or further research, or for applications like forensics, genetic testing, ancient DNA analysis or medical diagnostics. It’s hard to overstate the...

Duration:00:30:01

Genetics Shambles 9: The ethics of genetics

10/29/2020
Whenever the topic of genetics is mentioned this is always a question of ethics not far behind. Whether that is in Stem Cell research, genetic modification or even basic healthcare. In this show Robin chats to two experts in the field. Dr Sarah Chan is Chancellor’s Fellow in Ethics and Science Communicator in The Usher Institute at the University of Edinburgh. Professor Anna Middleton leads the Society and Ethics Research Group in Connecting Science. She is also Professor/Affiliate Lecturer...

Duration:00:53:38

S3.22 The Past, Present and Future of the Human Genome Project

10/22/2020
Thirty years ago this month saw the birth of one of the most audacious research programmes in biology: The Human Genome Project, an ambitious plan to read the DNA sequence of the entire human genome. Ten years later, in June 2000 - after billions of dollars, countless hours of DNA sequencing, and a huge amount of effort from an international collaboration from 20 institutions in six countries - the first draft of the Human Genome was unveiled. Dr Eric Green has seen the Human Genome Project...

Duration:00:30:33

Genetics Shambles 8: New genetic technologies

10/15/2020
Genetic technologies are improving all the time. Not just in sequencing, but in ways that improve our lives. From better crops to curing diseases. And, by pure chance, just hours before we went live with this show it was announced that Emmanuelle Charpentier and Jennifer Doudna had won the 2020 Nobel Prize for chemistry for their work with CRISPR and the technology of genome editing. Robin Ince chats to two experts in the field. Professor Alison Bentley leads the National Institute of...

Duration:00:50:49

S321 From Philadelphia to Baltimore: Tales of Chromosomes, Cancer Cells and Henrietta Lacks

10/8/2020
In this episode we’re taking a road trip from Philadelphia to Baltimore, exploring stories of chromosomal cut-and-paste, cancer cures and Henrietta Lacks’ incredible cancer cells. Studying human cells in the lab allows us to understand more about how they work, investigate the causes of disease, and design new treatments. But growing cells in the lab isn’t as easy as you might think. We explore the story of how Henrietta Lacks’s immortal cells (known today as HeLa cells) became the go-to...

Duration:00:33:19

Genetics Shambles 7: COVID expert panel 3

10/1/2020
Every couple of months we gather a new panel of experts for a Q&A on where things are at with our current understanding of the ongoing COVID-19 pandemic. With so much misinformation out there it’s important that you, the public and viewers, get a change to ask a panel of experts directly and unfiltered. For this, volume 3 of our COVID-19 Q&As Robin is joined by three experts. Dr Emma Hodcroft is a researcher at the University of Basel in Switzerland working on sequencing and builds of...

Duration:01:16:24

S3.20 The Future of Cancer: How Genomics is Transforming Research and Treatment for All

9/24/2020
In this episode, sponsored by Thermo Fisher Scientific, we’re taking a look at how genomic technologies are transforming cancer care - now and in the future, and the importance of making sure that these advances are available to all. With: - Greg Simon, past president of the Biden Cancer Initiative and former executive director of the White House Cancer Moonshot Task Force. - Jim Downing - president and CEO of St Jude Children’s Research Hospital - Dr Marianne Grantham, Head of...

Duration:00:45:07

Genetics Shambles 6: Dealing with pathogens

9/17/2020
Bacteria are all around us, and inside us. Some of these of these are fine, even good, but others are pathogens and cause disease. How do they evolve and how are we learning to cope with them through new research. And are we in danger of a new age of antibiotic resistance? Robin Ince is joined by three experts in the field. Dr Siouxsie Wiles is a microbiologist specialising in infectious diseases at the University of Auckland and has been one of the most prominent public faces of New...

Duration:00:55:10

S3.19 Making Babies and Getting Organised: Celebrating Hilde Mangold and Salome Gluecksohn-Waelsch

9/10/2020
In this episode we’re going back to the very beginning, telling the stories of the midwives of the field of developmental genetics, two talented researchers whose work helped to reveal the secrets of life in its very earliest stages: Hilde Mangold and Salome Gluecksohn-Waelsch. The tale of developmental genetics is a thrilling one, with everything you need for a good story. There’s politics, drama, upheaval, prejudice, and even a suspicious death. So hold on tight, this is a good one. Full...

Duration:00:26:44

Genetics Shambles 5: The evolution of cancer

9/3/2020
Cancer is the second leading cause of death in humans globally. But the catch all term of ‘cancer’ is often misunderstood. So what exactly is this cell disease that impacts so many of our lives? How long has it been around? How does it spread? What is our current understanding of its evolution and genetics? And the big question many of us have, where are we at with our fight against it? Robin Ince is joined by three experts in the field. Dr Kat Arney is a writer and presenter and former...

Duration:00:59:31

S3.18 Rare, Well Done: Progress and challenges in rare genetic disorders

8/27/2020
We take a look at the progress that’s been made in tackling rare genetic disorders (and the challenges that remain) and we hear from a prenatal genetic counsellor about how new tests are helping people carrying genetic variations make decisions about starting a family. With Dr Ron Jortner (founder and CEO of Masthead Biosciences and trustee of the Cambridge Rare Disease Network) and Genetic counsellor Kira Dineen. Full show notes, transcript, music credits and references online at...

Duration:00:35:22

Genetics Shambles 4: The sequence of everything

8/20/2020
Over the first four episodes of this series we’ve looked at COVID-19, historic epidemics, human evolution and the human genome and in each episode we’ve invariably talked about ‘sequencing’. Sequencing genomes and DNA of living things. So we thought it time to discuss the very act of sequencing itself. What is it, how do we do it, why do we do it and how can we get better at as technology improves. Robin Ince is joined by three experts in the field. Professor Jay Shendure is a human...

Duration:00:55:14

S3.17 Rebel Cell: Cancer, evolution and the science of life

8/13/2020
We bring you exclusive excerpts from my new book, Rebel Cell: Cancer, evolution and the science of life, exploring where cancer came from, where it’s going, and how we might beat it. Full show notes, transcript, music credits and references online at GeneticsUnzipped.com. Follow us on Twitter @GeneticsUnzip Genetics Unzipped is written and presented by Kat Arney with audio production by Hannah Varrall. This podcast is produced by First Create the Media for the Genetics Society - one of...

Duration:00:38:07

Genetics Shambles 3: Humans - Evolved and evolving

8/6/2020
Over millions of years Humans have evolved into becoming quite the dominant species on the planet. So, how did we get to now? What have we come from and how are we still evolving as a species? And what changes can we expect in the future in terms of diet, life span and population? Robin Ince is joined by three experts in the field. Professor Chris Stringer is an anthropologist and Research Leader in Human Evolution at the Natural History Museum in London. Dr Becky Wragg Sykes is an...

Duration:00:53:55

S3.16 Sickness and susceptibility: The ancient war between genes and disease

7/30/2020
We look at the ancient war between our genes and the pathogens that infect us, going back thousands of years to the Black Death and before, through to our very latest foe. With Claire Steves (King’s College London), Christiana Scheib (University of Tartu) and Lucy van Dorp (UCL). Full show notes, transcript, music credits and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip Genetics Unzipped is written and presented by Kat Arney with audio production by...

Duration:00:34:33

Genetics Shambles 2: A guide to the human genome

7/23/2020
The Human Genome Project has been referred to as one of the great feats of scientific exploration and discovery in human history. But what was it, and, more to the point, what is the human genome and why was sequencing it such a big deal? And in 2020, some 17 years after it was deemed completed, what has it helped us with in the fields of biology and medicine, and what is there still to discover? Robin Ince is joined by three experts in the field. Geneticist, broadcast and author of a...

Duration:01:05:03

S3.15 Pimp My Genome: the wonderful world of epigenetics

7/16/2020
We take a look at the world of epigenetics - finding out if more than DNA passes on to the next generation, whether Darwin was wrong and Lamarck was right, and how to pimp your genome. Plus - meet the Mickey Mouse Mice. Full show notes, transcript, music credits and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip Genetics Unzipped is written and presented by Kat Arney with audio production by Hannah Varrall. This podcast is produced by First Create the Media...

Duration:00:31:30

Genetics Shambles 1: COVID-19 and Learning from the Past

7/9/2020
What can research into past viruses and epidemics tell us about this new pandemic of COVID-19? What has changed in the world of genetics research since the time of HIV for example? Robin Ince chats to Dr Emma Hodcroft, a phylogenetics researcher from the University of Bath and Professor Sir Munir Pirmohamed, pharmacologist, geneticist and the NHS Chair of Pharmacogenetics at the University of Liverpool. To view previous episodes in the Genetics Shambles series head to...

Duration:00:51:36