The Lab Report

Such a random topic – gray hair? The technical term for hair graying is canities – again, what a strange word. Who knew? The basic physiology of hair growth and coloration is not something we really think about, but your hair can be a reflection of underlying health or disease. We often talk about the aging process as a marker of oxidative stress -So too with your hair. In this episode, we dive into the science of graying hair. From melanin loss to genetics to some surprising lifestyle connections, we separate fact from fiction and uncover the truth about your hair. Today on The Lab Report: Additional Resources: Genova Connect NutrEval Metabolomix+ Endo+ Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

Hiccups- that annoying and at times, painful reflex that sneaks up on you when you least expect it, and sometimes refuses to leave. But what are they really? Is there an evolutionary reason we’ve developed this reflex? When should you be concerned? Can we prevent them? In this episode, we break down the pathophysiology of hiccups (yes, there’s real science behind it) Knowing the science of why they occur, we can separate fact from fiction on how to cure them. From medical insights to strange home remedies, we’re getting to the root of the world’s most inconvenient reflex. Today on The Lab Report: Additional Resources: Genova Connect Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

Akkermansia muciniphila has been getting tons of great press recently. It’s a bacterium in the gut microbiome that thrives by supporting mucin production. However, its potential to enhance metabolic health and support weight management has paved the way for innovative probiotic solutions – which is exactly what a company called Pendulum has done! Pendulum’s products are backed by cutting-edge research showing clinical efficacy. Today we speak with Christina O’Connor, registered dietician and Senior Healthcare Account Manager at Pendulum Therapeutics. Christina breaks down all the latest research on Akkermansia muciniphila and how optimizing levels can lead to greater health outcomes. Today on The Lab Report: AkkermansiaAkkermansia Additional Resources: Pendulum Discount Codes: Healthcare professionals: Create a provider account HERE for wholesale pricing and get $50 off with code WSGENOVA50. Not a healthcare professional or just want to try it out? Get 20% off your first membership order at pendulumlife.com with code GENOVA at checkout. Genova Connect Discount Code: Are you a consumer interested in checking your levels of Akkermansia? Use the promo code PENDULUM20 for 20% off Genova Diagnostics’ Akkermansia Assessment Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

Advanced technologies and personalized approaches have been the hallmark of what we do here at Genova Diagnostics. We are frequently asked how this testing can be applied in pediatrics. Our testing is widely used to help empower parents to get to the root cause of some common childhood concerns. But there are some caveats to consider when interpreting results. Every child is unique – so why shouldn’t their healthcare be? In this episode, we dive into the world of personalized medicine for children and how Genova’s cutting-edge testing can unlock better health outcomes for kids. Today on The Lab Report: Additional Resources: GI Effects Metabolomix+ Food Sensitivity+ Cardio Check Genova Connect Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

We all know sugar isn’t great for our health. But is all sugar created equal? In this eye-opening podcast, we speak with the team from RxSugar. Their company creates and promotes a healthy sugar called allulose. Yes, a healthy sugar! Dr. Rick Johnson is a leading researcher on the hidden dangers of sugar. He discusses the impact of how sugar and fructose can hijack your cravings, fuel inflammation, and contribute to chronic disease. We also meet former Google Exec Neil Gyte. His personal journey toward metabolic health found him crossing paths with the science team at RxSugar. Neil joined their company and now continues his mission to make 1 billion people world-wide metabolically healthy while promoting the benefits of allulose. Listen in and enjoy this fascinating conversation! Today on The Lab Report: Additional Resources: RxSugar.com **PROMO CODE 1BMH for 20% Discount!*** (expires in June) YouTube Videos Dr. Nicholas Norwitz: Allulose: Healthiest Sugar in the World & GLP-1Thomas DeLauer: The Only Sweetener that Literally Shrinks Belly Fat Published Papers: Alluose RCT, glucose and insulin - Journal of Functional Foods Allulose and Weight Loss - Nutrients Allulose and GLP-1 release - NatureThe Metabolic and Endocrine Effects of a 12-week Allulose-Rich Diet - NutrientsBrain activity and sugar - Nutr Neuroscience Sweet Taste Receptor Activation related articleAllulose, Fructose, Glucose and the Small Intestine - NutrientsAlluose & Tight Junction Regulation - Journal of Functional Foods Allulose and the gut MicrobiotaAllulose and High Fat Diets - Microbiome - Nutrients Fructose & Metabolic Syndrome - Cell Metabolism Fructose, Intracellular Pathway - J Biol Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

Garlic isn't just a kitchen staple—it’s a natural powerhouse of health benefits! Packed with antioxidants and sulfur compounds like allicin, garlic supports heart health by lowering blood pressure and cholesterol, strengthens the immune system, fights inflammation, and so much more. With its antibacterial and antiviral properties, garlic has been used for centuries as a natural remedy for colds, infections, and overall wellness. Whether eaten raw, cooked, or taken as a supplement, garlic is a simple yet powerful way to boost your health naturally. Join us as we discuss this unsung herbal hero. Today on The Lab Report: Additional Resources: Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

Longevity isn’t about adding years to your life- it’s about adding life to your years! We know there are many variables to health such as diet, movement, sleep, social connection, fresh air and sunlight. Each are important but some aren’t easily measured. The Roseto Effect reveals the surprising power of tight-knit communities, social bonds, and old-world traditions in shaping our health. Join us as we tell the story of a small town in Pennsylvania called Roseto. Can community be the ultimate medicine? Today on The Lab Report: Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

Ever wonder what happens when your voice suddenly decides to take a vacation? In this episode, we explore the mysterious condition of laryngitis. From causes to symptoms, we can help you discover the best ways to recover and protect your voice. Whether you're dealing with laryngitis now or just curious about how it works, this episode will give you the answers you need. Tune in for all the insights into a silent struggle! Today on The Lab Report: Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

When it comes to holiday traditions, we think of decorating Christmas trees, baking cookies, the Elf on the Shelf, or lighting a menorah. But holiday traditions are far more unusual and diverse throughout the world. Some might really surprise you! On today’s episode, we touch on some unusual international holiday customs you’ve likely never heard while sprinkling in some clinical pearls. We also continue our podcast tradition of reading The Lab Report’s special rendition of ‘Twas the Night Before Christmas. Today on The Lab Report: Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

As the days get shorter and the air turns crisp, cold and flu season sneaks in bringing sniffles, coughing, fatigue, and fever. It’s a time when germs spread easily, and our immune systems face a tough challenge. When you add holiday stress in the mix, it becomes even more important to boost your defenses, and optimize your immunity. In today’s episode, we offer tips to help you unlock your body’s natural defenses as we try to navigate cold and flu season. This podcast has everything you need to stay ahead of seasonal sickness so you can enjoy your holiday. Today on The Lab Report: · 3:00 Yep -Patti is still sick · 5:05 Vitamin D is awesome · 8:50 Sleep quantity and quality · 12:00 Michael’s rant on herbal therapies · 17:40 The importance of zinc · 20:05 Cortisol and dampened immunity · 22:55 Honorable mentions Additional Resources: Genova Connect Manna Food Bank Eblen Charities United Way Asheville Beloved Asheville Habitat for Humanity - AVL Rural Organizing and Resilience Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

The holiday season is a time of joy, connection, and celebration – but to be honest, it can also be incredibly stressful. Between hosting dinners, finding the perfect gifts, managing finances, and navigating family dynamics, it’s easy to feel overwhelmed. The good news? You’re not alone and there are ways to reclaim the magic of the season without losing your sanity. In today’s podcast, we dive into the science of stress and how the vagus nerve holds the key to calm. Discover how breathwork, mindfulness, and gratitude can transform your holiday experience, helping you stay grounded, joyful, and resilient. Tune in and gift yourself some peace this season! Today on The Lab Report: · 3:10 Holiday season is here! · 6:20 Stressors and getting to the root cause of expectations · 8:40 Sympathetic vs. Parasympathetic – neuroendocrine responses · 11:30 Vagus nerve · 13:15 Breathwork techniques, singing, gargling, laughing · 18:15 Mortality of holiday season · 20:15 Mindfulness and joy · 24:00 Gratitude Additional Resources: Genova Connect Manna Food Bank Eblen Charities United Way Asheville Beloved Asheville Habitat for Humanity - AVL Rural Organizing and Resilience Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

Where to begin? It’s been a few weeks since you’ve heard from us – thank you so much for your amazing support and patience. As you may know, Hurricane Helene brought devastation to western North Carolina, eastern Tennessee, South Carolina, Georgia, and Florida. Genova Diagnostics is headquartered in the heart of Asheville, North Carolina. With that, it’s been a challenging few weeks. But the heroic efforts of many, and the resilient spirit of our team have us back up and running. Genova continues to support our local community- many of whom are still struggling and have lost everything. #WNCStrong Today’s episode is a bit different than usual. It’s our story. Our lessons learned. Genova’s story of resilience when faced with a devastating, historic hurricane. Additional Resources: Genova Connect Manna Food Bank Eblen Charities United Way Asheville Beloved Asheville Habitat for Humanity - AVL Rural Organizing and Resilience Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

Gastroesophageal reflux disease (GERD), or heartburn, is incredibly common as is the use of stomach acid suppressing medication. But what if there is far more to the story than stomach acid? There are many other factors to consider in a patient with heartburn. We are going to dive into the physiology of gastric acid, gastric hormonal signaling, and a slew of medications and foods that might be the real culprit. Are PPI’s over prescribed? Are we missing the picture? Tune in to find out. In today’s episode, we tackle some burning questions about GERD and try to get to the root cause. Are acid suppressing medications always the answer? Perhaps the story is not that simple. Today on The Lab Report: Additional Resources: Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

Occasionally, there are new and novel things introduced into the functional medicine and biohacker space that catch our attention. Lately, you might have heard a lot of people talking about the amazing health benefits of “nootropics,” but what are they? Coming from the name of the Greek word Nous (meaning “mind”), nootropics are medicines designed to improve cognitive function and protect the brain. Many of us could use a healthy dose of cognitive support to help us through our busy lives, but what is the truth about nootropics and where can we find them? In today’s episode, we discuss the what, how, and why of nootropics. We explain what things are considered nootropics and how they work in the body. We also discuss what may be unexpected nootropic things you can do everyday that may not even be termed a nootropic. Listen for more information on how you can help get the most out of your cognition. Today on The Lab Report: not Additional Resources: Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

Ok, we know what you’re thinking…. Artichokes? Really? Yes really. It may seem a bit out of left field, but you’d be surprised at the many health benefits from either eating artichokes or taking an extract supplement. As a vegetable, it contains fiber, vitamins, minerals, and antioxidants. Extracts made from artichoke leaves, stems, and roots have been used as nutraceutical agents to support the GI tract, liver, and cardiovascular system. But why? In this episode, we peel back the layers of the artichoke – a very mysterious plant indeed. Is it possible to boost your health with artichoke leaf extract? Tune in to find out! Today on The Lab Report: Additional Resources: Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

Mast Cell Activation Syndrome (MCAS) has become a hot topic in functional medicine. Mast cells are an integral part of the body’s immune system. They can be found in areas of exposure such as mucosal membranes, the lining of the GI tract, skin, and airways. Mast cells are responsible for storing important chemical mediators like histamine and others which help to instigate allergic responses. Mast cell disorders arise when there are too many mast cells, or they become hyperreactive. That being said, these conditions are often misunderstood, and diagnoses are sometimes misused. In today’s episode, we focus on the role of mast cells and histamine in the immune response. We discuss the different mast cell activation disorders, how to diagnose them, and what you can do about it. Today on The Lab Report: Additional Resources: IgE Food Antibodies Profile IgE Inhalants - Allergy Profile IgE Mold - Allergy Profile Methylation Panel Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

The gut microbiome harbors trillions of commensal organisms which play a central role in our health. This community is sometimes referred to as our hidden metabolic organ due to its immense impact. Our diet and lifestyle play an important role in feeding the microbiome and keeping the colonies in balance. Should we be concerned if any one bacterial colony overgrows? Today we discuss the commensal bacteria Desulfovibrio. Since this genus of bacteria can reduce sulfate and make hydrogen sulfide gas, overgrowth can have clinical implications. Listen in for more information on why you should care and what you can do about it. Today on The Lab Report: DesulfovibrioDesulfovibrio Desulfovibrio Desulfovibrio Additional Resources: Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase** GI Effects Stool Profile Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

There are a lot of terms bantered about in the biohacker and longevity space. With that, you’ve likely heard of mTOR – mechanistic (mammalian) target of rapamycin. But what exactly is it? mTOR is a key regulator in your body’s metabolic and growth processes. It integrates various signals, including nutrients and growth factors, to control processes like protein synthesis, autophagy, and lipid metabolism. Because it regulates growth, dysregulation of mTOR has been implicated in various diseases, including cancer. In today’s episode, we simplify the science behind mTOR – mechanistic target of rapamycin. This crucial enzyme may be the key to unlocking groundbreaking advancements in wellness, anti-aging, disease prevention, and health optimization. Today on The Lab Report: Additional Resources: Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

Multi-omics is the layering of genetic information (genomics) with laboratory biomarker results (metabolomics) to understand the root cause of disease and risk. This educational series focuses on genetic variants in specific enzymes and explains how to evaluate the systemic effects. Today’s episode revolves around the enzyme cystathionine-beta-synthase (CBS). This enzyme is important for homocysteine metabolism, sitting at a branch point between two important cycles: methylation and transsulfuration. The action of this enzyme is important for balancing the critical functions of methylation with the creation of glutathione and energy. Listen to understand why this enzyme is important and what a genetic variant in CBS might mean for you and your patients. Today on The Lab Report: Additional Resources: Methylation Panel Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase** Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and show not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.

Many of us have heard of glutathione and understand that it is a powerful antioxidant – but why? What is it? How does it work? Understanding the mechanisms of this crucial molecule can help you fully grasp its importance. Oxidative stress and the damage of free radicals underlie the aging process and many chronic conditions. There’s no greater tool to combat oxidative stress than glutathione. In today’s episode, we break down the science of glutathione and redox reactions. You will learn how glutathione works, how to support optimal levels, and how it connects to the methylation cycle! Today on The Lab Report: Additional Resources: Genova Connect **PROMO CODE** TheLabReport20 for 20% off your purchase NutrEval Methylation Panel Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests. See omnystudio.com/listener for privacy information.