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This Week In Virology

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Episodes

TWiV 544: Immunogaga

4/21/2019
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The TWiV team reveals the repertoire of anti-viral antibodies in newborn humans, and a complement protein that binds the adenovirus capsid and prevents release of the viral DNA. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode anti-viral antibodies Complement protein inside cellsImage creditLetters readJolene Weekly Science Picks Brianne - Doctors use HIV in...

Duration:01:47:29

TWiV 543: Stoned and senile

4/14/2019
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The TWiV team discusses Medusavirus, isolated from a hot spring in Japan, and induction of neurodegeneration by recurrent herpes simplex virus 1 infection of mice. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Medusavirus herpes simplex virus-1Image creditLetters readJolene Weekly Science Picks Brianne - How to Take a...

Duration:01:48:09

TWiV 542: Inside Microbiotix

4/7/2019
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Vincent travels to Microbiotix, Inc, a biopharmaceutical company in Worcester, MA to speak with four members of the company about their discovery and development of small molecule drugs that target serious infectious diseases. Host: Vincent Racaniello Guests: Terry Bowlin, Zach Aron, Grace Lui, and Islam Hussein Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Microbiotix, Inc.MBX-400pipelinepublicationsJolene Listener Pick Islam- ...

Duration:01:04:59

TWiV 541: Cloaking devices

3/31/2019
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The TWiVers present mitoviruses, which infect mitochondria, and how quasi-enveloped hepatitis A virus gets naked again. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode plant mitovirusesquasi-enveloped HAVImage creditLetters readJolene Weekly Science Picks Alan- Where and when to see cherry blossoms Dickson- Nebraska floods Kathy- Peeps fungal infection...

Duration:01:28:45

TWiV 540: Wascally wiruses

3/24/2019
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The TWiVstars reveal the diversity of herpes simplex virus type 2 in a neonatal population, and parallel adaptation of rabbits in three countries to myxoma virus. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Alan Dove, and Kathy Spindler Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Diversity of HSV2Adaptation of rabbitsPrincipal component analysis Image creditLetters readJolene Weekly Science Picks Alan- The...

Duration:01:48:46

TWiV 539: Multitudes contain me

3/17/2019
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The TWiV hosts present two potentially seminal papers, on long-distance chemoattraction of a host by a chlorovirus, and replication of a nanovirus across multiple cells in a plant. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Paul Has Measles Germanlure hostsMulticellular replication Image creditLetters readJolene Weekly Science...

Duration:01:41:45

TWiV 538: An Iowa caucus of viruses

3/9/2019
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TWiV travels to the University of Iowa to speak with Wendy Maury and Stanley Perlman about their research on Ebolavirus entry and coronavirus pathogenesis. Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Guests: Wendy Mauryand Stanley Perlman Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode TIM-1 is receptorLassa virusneuronal deathviral demyelinationJolene Intro music is by Ronald Jenkees. Send your virology questions...

Duration:01:01:33

TWiV 537: Boundary issues

3/3/2019
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The Scholars of the Podcast reveal ribosomal proteins encoded in viral genomes, and a protein cell receptor for bat influenza viruses. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode European Congress of Virology 2019Clinical Virology Symposiumjudges needed endorses measles vaccineencode ribosomal proteinsreceptorTWiV 173Letters readJolene...

Duration:01:43:49

TWiV 536: A flock of seagulls, a herd of seals

2/24/2019
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Vincent and Alan travel to Tufts Veterinary School where they meet up with members of the Runstadler lab to talk about their work on influenza virus circulation in water birds and seals. Hosts: Vincent Racaniello and Alan Dove Guests: Jonathan Runstadler, Nichola Hill, Wendy Puryear, and Kate Sawatzki Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Cummings School of Veterinary Medicinegrey sealsAlaskan wild birdsreplication in...

Duration:01:28:18

TWiV 535: Miles to go before I leak

2/17/2019
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The TWiV team discuss the use of quantum dots to study uncoating of influenza virus in real time, and induction of endothelial dysfunction by flavivirus NS1 proteins in a tissue-specific manner. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode European Congress of Virology 2019Clinical Virology Symposiumjudges neededvisualize influenza entryQuantum dots...

Duration:01:36:09

TWiV 534: Portal to the METTL

2/10/2019
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The TWiV crew reveal a unique portal on the calcivirus capsid formed upon receptor engagement, and the regulation of interferon responses in virus-infected cells by methylation of mRNA. Hosts: Vincent Racaniello, Dickson Despommier, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode European Congress of Virology 2019Clinical Virology Symposiumjudges neededCalicivirus portal long versionm6A...

Duration:01:34:43

TWiV 533: Recurring threads

2/3/2019
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The TWiVosophers review the Chinese plasma virome revealed by non-invasive prenatal testing, and a new filovirus genome from bats in China. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode ASV 2019European Congress of Virology 2019Clinical Virology Symposiumjudges needed Jerard Hurwitznow in Frenchplasma viromeTWiV 435Měnglà filovirus virus nameOrtervirales...

Duration:01:51:57

TWiV 532: Morbillivirus had a little lamb

1/27/2019
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The TWiVers discuss the spread of African swine fever virus and its threat to pig farming, and the zoonotic potential of peste des petits ruminants virus. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode TWiV listener surveyASV 2019European Congress of Virology 2019Clinical Virology Symposiumjudges needed does not let go ASF outbreak African swine feverreview wild...

Duration:01:38:51

TWiV 531: Circ du RNA

1/20/2019
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Patrick Moore returns to TWiV to discuss the discovery from the Chang-Moore laboratory of circular RNAs in cells infected with herpesviruses. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler Guest: Patrick Moore Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode TWiV listener surveyASV 2019European Congress of Virology 2019Clinical Virology Symposiumjudges neededCancer virology DI particlescircular...

Duration:01:47:11

TWiV 530: Quiet please!

1/13/2019
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Steve Goff returns to TWiV to discuss the work of his laboratory on how retroviral genomes are silenced in infected cells. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler Guest: Steve Goff Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! 🎼 They’ll histone you when you start to transcribe, And they’ll histone you just for tryin’ to get by, So be careful when you uncoat your genome, ‘Cause everybody must histone. Links for...

Duration:01:42:47

TWiV 529: Rueckert Road

1/8/2019
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At the University of Wisconsin-Madison, Vincent meets up with one of his virology heroes, Roland R. Rueckert, to talk about his research and his second career as a forest manager. Host: Vincent Racaniello Guest: Roland R. Rueckert Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Videofirst paperPurificationviral structuregel fractionatorgene orderprotease discoveryprocessing mapNomenclatureBlack beetlecrystallizationmAb binding...

Duration:01:15:51

TWiV 528: Our annual recapsidation

1/6/2019
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In the first episode for 2019, the TWiV team reviews the amazing virology stories of the past year. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode TWiV listener survey ASV 2019 Satellite SymposiaCrowdfundingTWiV World Tour 2018 t-shirtTWiV 505TWiV 519 one twoWolbachiaTWiV 506World Mosquito ProgramTWiV 491TWiV 526TWiV 478TWiV 494TWiV 495TWiV...

Duration:02:07:53

TWiV 527: City mouse, country mouse

12/30/2018
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The TWiV team summarizes the discovery of Sin Nombre virus, and presents evidence that neurotropic flaviviruses can cause intestinal dysmotility syndromes after systemic infection of mice. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode TWiV listener survey ASV 2019 Satellite SymposiaCrowdfundingexhibitTWiV 501 hantavirus outbreakDeath at the...

Duration:01:26:41

TWiV 526: In the beginning there was pol

12/23/2018
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The TWiV hosts discuss the distribution of prions in the eyes of patients with sporadic Creutzfeldt-Jacob disease, and the origins and evolution of RNA viruses. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode TWiV listener survey ASV 2019 Satellite SymposiaCrowdfundingAaron KlugsCJD eyesEvolutionThe RNA WorldImage creditLetters readJolene Weekly Science Picks Alan -...

Duration:01:44:17

TWiV Special: Vaccines Did Not Cause Rachel's Autism

12/19/2018
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Vaccine scientist, pediatrician, and autism dad Peter Hotez talks about his new book, Vaccines Did Not Cause Rachel's Autism. Host: Vincent Racaniello Guest: Peter Hotez Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Peter Hotez Peter HotezVaccines Did Not Cause Rachel's AutismJolene Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

Duration:00:18:59