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This Week In Virology

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Episodes

TWiV 515: When virus is in retrograde

10/14/2018
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The TWiV team notes the passing of Tom Steitz, an outbreak of acute flaccid myelitis in the US, a continuing Ebola virus outbreak in DRC, respiratory vaccinia due to inhalation of ground up rabbit skin, and how a human papillomavirus capsid protein directs virus-containing endosomes towards the nucleus. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this...

Duration:01:38:49

TWiV 514: Staying below the ADAR

10/7/2018
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The TWiVumvirate reviews this years crop of Nobel Prizes, and how cells prevent leakage of mitochondrial double-stranded RNA into the cytoplasm, which would otherwise lead to the production of interferon. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode programapplication materialspenalized by CNRSpdfpdfpdfPeace PrizeMitochondrial dsRNALetters readJolene...

Duration:01:48:27

TWiV 513: Double-stranded in Belgium

9/30/2018
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From the 13th International Symposium on dsRNA viruses in Belgium, Vincent speaks with Harry Greenberg about his career and his work on rotaviruses, noroviruses, hepatitis B virus, and influenza virus. Host: Vincent Racaniello Guest: Harry Greenberg Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode 13th dsRNA Virus SymposiumHepatitisInterferon treatmentMycoplasmamutantsNorwalk virus infectionRotavirus rescueCold-adaptedcorrelates of...

Duration:01:02:03

TWiV 512: Flexuous SUMO wrestlers

9/23/2018
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Anne Simon joins the TWiV team to talk about plant viruses, including plum pox virus that devastates nut and stone fruit trees, and a geminivirus protein that regulates viral DNA synthesis. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, Brianne Barker, and Anne Simon Click arrow to play Download TWiV 512 (62 MB .mp3, 103 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Gordon ConferencePotyvirusPlum pox...

Duration:01:42:47

TWiV 511: Accessory found guilty in DC

9/16/2018
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Ned Landau joins the TWiV team to discuss restriction of HIV replication by SAMHD1, and a viral antagonist that can be used to produce a dendritic cell vaccine. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker Guest: Ned Landau Become a patron of TWiV! Links for this episode Gordon ConferenceTWiV #1restricts HIV-1 replicationdiverse retrovirusesindependent of uncoatingTransduction of myeloid cellsLetters readJolene Weekly Science...

Duration:01:48:53

TWiV 510: Retroviruses at Cold Spring Harbor

9/9/2018
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Vincent and Dickson travel to the 44th Retrovirus meeting at Cold Spring Harbor Laboratories, where they speak with John Coffin, Stephen Hughes, Ya-Chi Ho, and Matt Takata about the meeting and their work on HIV-1. Hosts: Vincent Racaniello and Dickson Despommier Guests: John Coffin, Stephen Hughes, Ya-Chi Ho, and Matt Takata Become a patron of TWiV! Links for this episode Retrovirus Meeting 2018TWiV 320HIV-1 reservoirHIV-1 latencyCG dinucleotide suppressionJolene Intro music is by...

Duration:01:04:11

TWiV 509: 41,103 bases under the sea

9/2/2018
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The TWiV team considers whether those who can do, can't teach, and newly discovered viruses of planarians and Aplysia with the largest RNA genomes. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Kathy Spindler and Brianne Barker Become a patron of TWiV! Links for this episode Gordon ConferenceBeijerinck Prize Bioterrorism and Biocrimes History of Biological Warfare Those Who Can Do, Can't TeachPlanarianAplysia Image creditLetters read Weekly Science Picks Brianne- Climate...

Duration:01:46:25

TWiV 508: Bioweapon

8/26/2018
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Jens returns to present a brief history of bioweapons, with a focus on the program in the Soviet Union, the largest ever undertaken, and his experience working in the decommissioned Soviet bioweapons laboratory known as Vector. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Kathy Spindler Guest: Jens Kuhn Become a patron of TWiV! Links for this episode Russia's Bioweapons LabsMedical Aspects of Biological WarfareThe Soviet Biological Weapons ProgramBiological Threats in...

Duration:02:07:37

TWiV 507: The fusion of form and function

8/19/2018
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The TWiV team discuss the biology of Ebola viruses, and how localization of the membrane proteins of vaccinia virus drive function: the fusion machinery sits at the tips of virions, and binding proteins are at the sides. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker Become a patron of TWiV! Links for this episode Viruses & Cells Gordon ConferenceOutbreakOutbreakEbola virus outbreakEbola virus outbreaksnomenclaturedistribution...

Duration:01:58:31

TWiV Special: David Tuller is PACEman

8/17/2018
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David Tuller returns to provide an update of his investigative work to expose the methodological and ethical problems with the PACE trial for ME/CFS. Host: Vincent Racaniello Guest: David Tuller Become a patron of TWiV! Links for this episode ArticleAustralian tripown goalLightning processParliamentconflict of interestLancet 3.0still champions GETImage Credit Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

Duration:01:08:35

TWiV 506: A Cafeteria full of jelly rolls

8/12/2018
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The TWiVniks explain how the three-dimensional structure of the giant Cafeteria roenbergensis virus suggests a new mode of assembly, and the apparent elimination of dengue fever in an Australian city by release of mosquitoes harboring Wolbachia. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Brianne Barker Become a patron of TWiV! Links for this episode Viruses & Cells Gordon Conferencestrains distinctImmunizationsCafeteria roenbergensis viruslaboratoryCroV moviesScaled...

Duration:01:37:27

TWiV 505: Rosebola

8/5/2018
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The TWiV hosts review persistence of Ebola virus after the end of the Liberian outbreak, and the potential role of two herpesviruses in the pathogenesis of Alzheimer's disease. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, Kathy Spindler and Brianne Barker Become a patron of TWiV! Links for this episode Viruses & Cells Gordon Conferencescience advisorhorses racingPersistenceEbolavirus outbreakherpesvirusesbeta-amyloidLetters read Weekly Science Picks Alan -...

Duration:02:02:09

TWiV 504: Flying foxes and barking pigs

7/29/2018
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The TWiVerinos discuss Nipah virus and the recent outbreak in India, and the first cast of polio in Papua New Guinea in 18 years. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker Become a patron of TWiV! Links for this episode Viruses & Cells Gordon ConferenceTWiV 501: OutbreakNipah virusoutbreakDo we need to worry of batsno longer polio-freeendgameLetters read Weekly Science Picks Alan - Glaciers of the Rockies aerial photos Rich - SpaceX...

Duration:01:50:29

TWiV 503: The greening of TWiV

7/22/2018
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Vincent, Rich and Kathy travel to ASV 2018 at the University of Maryland to speak with Svetlana Folimonova and Anne Simon about their work on viruses that infect plants. Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Guests: Svetlana Folimonova and Anne Simon Become a patron of TWiV! Links for this episode SimonFolimonovasuperinfection exclusion3'-CITEsVideo Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

Duration:01:01:31

TWiV 502: Texas road phage

7/13/2018
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The TWiV team travels to Texas A&M University, home of the Center for Phage Technology, where they speak with Ry Young and Jason Gill about their work on viruses that infect bacteria. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Guests: Jason Gill and Ry Young Become a patron of TWiV! Links for this episode Center for Phage Technologyphage therapybiolipid extractionantibioticAcinetobacter phage depolymerasephage QβVideo Intro music is by Ronald Jenkees. Send...

Duration:01:31:51

TWiV 501: Outbreak

7/8/2018
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Vincent visits the Smithsonian Institution and speaks with Sabrina Sholts, Jon Epstein, and Ed Niles about the exhibit Outbreak: Epidemics in a Connected World. Host: Vincent Racaniello Guests: Sabrina Sholts, Jon Epstein, and Ed Niles Become a patron of TWiV! Links for this episode Sabrina SholtsJonathan EpsteinOutbreakASM partnersmuseum objectVideo Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

Duration:01:29:35

TWiV 500: Keep virology weird

6/30/2018
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The entire TWiV team visits The University of Texas in Austin to record episode #500 with guests Jinny Suh, Jason McClellan, and Jon Huibregtse. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Guests: Jinny Suh, Jason McClellan, and Jon Huibregtse Become a patron of TWiV! Links for this episode science podcastsImmunize TexasMcClellan LabHuibregtse LabCenter for Infectious DiseaseVideo of this episode Weekly Science Picks Alan - The Airplane...

Duration:02:00:09

TWiV 499: Good virologists go to Halifax

6/24/2018
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Vincent and Alan travel to the Canadian Society for Virology meeting in Halifax, Nova Scotia to speak with Nathalie and Craig about their vision for the society, and with Kate and Ryan about their careers and their research. Hosts: Vincent Racanielloand Alan Dove Guests: Nathalie Grandvaux, Craig McCormick, Kate O'Brien, and Ryan Noyce Become a patron of TWiV! Links for this episode World TourCSV 2018To wheezeSynthetic Intro music is by Ronald Jenkees. Send your virology questions and...

Duration:00:58:13

TWiV 498: Salivating at ASM Microbe

6/17/2018
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Vincent, Kathy and Rich travel to ASM Microbe 2018 in Atlanta where they speak with Stacy Horner and Ken Stapleford about their careers and their research. Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Guests: Stacy Hornerand Ken Stapleford Become a patron of TWiV! Links for this episode World Tourgo viralN6-methyladenosineevolution Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

Duration:01:08:27

TWiV 497: Europic 2018

6/10/2018
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At Europic 2018, a meeting on picornaviruses in the Netherlands, Vincent speaks with Sasha Gorbalenya, Jim Hogle, Ann Palmenberg and Frank van Kuppeveld about their careers and their research. Hosts: Vincent Racanielloand Rich Condit Guests: Sasha Gorbalenya, Jim Hogle, Ann Palmenberg, and Frank van Kuppeveld Become a patron of TWiV! Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

Duration:00:59:43