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This Week in Evolution

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Episodes

TWiEVO 42: Who's who in your genome

4/24/2019
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Nels and Vincent review the contribution of multiple Denisovan lineages to the modern Papuan genome. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Denisovan ancestriesProf Murray CoxImage creditLetters readJolene Science Picks Nels- Sydney Brenner - What Genomes Can Tell Us About the Past Vincent- Scientific Communication in a Post-Truth Society Music on TWiEVO is performed by Trampled by Turtles Send your...

Duration:01:18:29

TWiEVO 41: Where do baby genes come from?

3/20/2019
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Nels and Vincent explore the evolution of new protein-coding genes de novo from nocoding DNA sequences, using the antifreeze protein of northern codfish as a model. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO diversity FrankentomatoesImage creditJolene Science Picks Nels- Science at Sundance reviews Vincent- The Rise and Fall of Scientific Authority Music on TWiEVO is performed by Trampled by Turtles Send...

Duration:01:24:07

TWiEVO 40: Eau de bee

2/14/2019
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Nels and Vincent move back to reproductive isolation - this time, pre-zygotic, in the charismatic orchid bee where the males make chemically distinct perfumes to attract mates of the same species. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Olfactory receptor gene Image creditJolene Science Picks Nels- Nature Zen: Orchid Bees Are Shiny Vincent- What You Believe About Science Denial May Be All Wrong Music on...

Duration:01:11:36

TWiEVO 39: In a Legionella of their own

1/26/2019
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Nels and Vincent look at the intracellular bacteria Legionella from an evolutionary perspective: the role of gene acquisition and reshuffling from plants, animals, fungi, and archaea in the emergence of human pathogens. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO 18,000 effectorsLegionella Carmen Buchrieser labHoward Shuman Science Picks Nels - Science in Film (twitter) Vincent - Lunar...

Duration:01:17:09

TWiEVO 38: Evolving to evolve

12/24/2018
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Nels and Vincent reveal a highly conserved protein that acts as an evolvability factor, increasing mutation and the ability of bacteria to become resistant to antibiotics. Hosts: Nels Elde and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO antibiotic resistance error thresholdImage creditLetters read Science Picks Nels- Science/nature illustrator/artist Rachel Ignotofsky (website, Etsy shop) Vincent- Life Ascending by Nick Lane Music...

Duration:01:20:39

TWiEVO 37: A tangled tree on the Quammens

11/17/2018
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David Quammen joins Nels and Vincent to talk about his new book, A Tangled Tree, including evolutionary trees, Carl Woese, Lynn Margulis, horizontal gene transfer, and much more. Hosts: Nels Elde and Vincent Racaniello Guest: David Quammen Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO TWiV 408, Boston QuammensGilroy Gardens Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Duration:01:31:01

TWiEVO 36: All's not quiet on the telomeric front

10/24/2018
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Mia joins Nels and Vincent to unravel their finding that the transposons that maintain the ends of chromosomes in Drosophilahave evolved in conflict with the genome. Hosts: Nels Elde and Vincent Racaniello Guest: Mia Levine Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO Levine Lab at U Pennwithout telomeraseLetters read Science Picks Nels - Cinema Science podcast Vincent - Mastodon bones unearthed (Instagram, Grand Rapids News) Music on TWiEVO is...

Duration:01:15:05

TWiEVO 35: Strawberry sex chromosomes forever

9/21/2018
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Nels and Vincent reveal that female-specific DNA associated with sex in strawberries has repeatedly changed its genomic location, possibly linking new genes with sex. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO Jumping sex genesRed Queen by Matt Ridley Image creditLetters read Science Picks Nels - New snailfish and Cloned crayfish Vincent - A PhD Lab Coat Ceremony Listener Picks Steve - Diversity in simple blobs Justin - On Growth and Forms by D'Arcy...

Duration:01:36:09

TWiEVO 34: You don’t know what you’ve got ‘til it’s PON

8/16/2018
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Nels and Vincent discuss how the loss of an enzyme in marine mammals millions of years ago now makes them at risk for neurotoxicity caused by human-made organophosphorous pesticides. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO Ancient lossesBig Yellow TaxiImage creditLetters read Hey farmer farmer put away the chlor-pyri-fus I don’t care about spots on my apples Leave me the manatee and walruses Science Picks Nels - New dinosaur discovered in Utah Vincent -The...

Duration:01:22:25

TWiEVO 33: Fly by virus

7/24/2018
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Nels and Vincent are astounded by the finding of an insect-derived virus in a fungus that manipulates the behavior of flies. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO Virus in fungus in flyTWiV 443Benzer Lecturefungal fly pathogenE. muscae genomenew iflavirus Science Picks Nels - Mindsuckers; getting photos; Anand Varma photos Vincent - Happy Birthday Gregor Mendel Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to...

Duration:01:20:07

TWiEVO 32: Never not neutral

6/19/2018
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Matt joins Nels and Vincent to discuss the neutral theory of evolution and its rejection in light of genome-scale data. Hosts: Nels Elde and Vincent Racaniello Guest: Matt Hahn Become a patron of TWiEVO Hahn LabMolecular Population GeneticsNeutral theoryFallacySplendor and miseryImage creditLetters read Science Picks Nels - Inaugural Transposon Day Vincent - How many human genes? Listener Pick Anne- Plants repeatedly lose ability to obtain nitrogen Music on TWiEVO is performed by...

Duration:01:19:09

TWiEVO 31: Virus archaeology, or when the human genome is the junk

5/19/2018
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Nels and Vincent present ancient hepatitis B virus genome sequences from Bronze Age to Medieval period human remains. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO hepatitis B virus genomesancient HBV genomesImage creditLetters read Science Picks Nels - Sampling whale breathwith drones (Preprint) Vincent - Verge Science Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Duration:01:21:21

TWiEVO 30: Driving Miss Maize-y

4/21/2018
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Nels and Vincent reveal how a motor protein in corn causes preferential transmission of chromosomes to egg cells, leading to non-Mendelian inheritance. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO Molecular Evolution and the CellSelfishDawe LabImage creditLetters read Science Picks Nels - Craypot stinkhorn mushroom (Colus pusilus) Vincent -Doubts raised over plan to release herpesvirus to wipe out carp Music on TWiEVO is performed by Trampled by Turtles Send your...

Duration:01:15:05

TWiEVO 29: Evolution on the wing

3/21/2018
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Nels and Vincent discuss the evolution of blood feeding to nonbiting in a mosquito, and evolution of bacterial virulence in the house finch caused by incomplete host immunity. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO Molecular Evolution and the Cellblood feeding to nonbitingnot a free lunchevolution of virulenceImage creditLetters read Science Picks Nels - IDEA and Impossible Foods Vincent - it is NOT junk Music on TWiEVO is performed by Trampled by...

Duration:01:42:21

TWiEVO 28: Genetics of skin pigmentation in Africa

2/27/2018
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Sarah Tishkoff joins Nels and Vincent to explain work from her laboratory on the genetic basis of skin pigmentation in Africans. Hosts: Nels Elde and Vincent Racaniello Guest: Sarah Tishkoff Become a patron of TWiEVO Molecular Evolution and the CellAMA on Redditskin pigmentationImage credit Science Picks Nels - In Defense of Plants (Shrew Loo) Vincent - Contribution of NIH funding to new drug approvals Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions...

Duration:01:19:35

TWiEVO 27: Coldevo

1/13/2018
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Taking a cue from the recent frigid weather, Nels and Vincent explore how modifications of a neuronal cold-sensing channel regulate diminished cold sensitivity in hibernating mammals. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO don't mind the coldImage creditLetters read Science Picks Nels - Undergrad podcasters from Stonehill College Vincent - Viruses at Target Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to...

Duration:01:18:23

TWiEVO 26: My Scientist Vinny

12/7/2017
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Vinny Lynch joins Nels and Vincent to discuss how a zombie gene in elephants protects these large, long lived animals from cancer. Hosts: Nels Elde and Vincent Racaniello Guest: Vinny Lynch Become a patron of TWiEVO Lynch Labinduces apoptosisImage credit Science Picks Nels - Animalism Vincent - Voyager I fires up thrusters after 37 years Vinny - Rollin' Wild Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Duration:01:13:33

TWiEVO 25: Pigeons show the way

11/22/2017
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Nels and Vincent discuss a genomic analysis of the passenger pigeon, which shows that species with large and stable populations may be at risk of extinction after a sudden environmental change. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO genomic diversityImage creditLetters read Science Picks Nels - Video of nematophagous fungi Vincent - How should novelty be valued in science? John - Evo-Devo (Despacito Biology Parody) Melanie - What's in John's Freezer Music...

Duration:01:38:23

TWiEVO 24: Good viruses visiting bad neighborhoods

10/26/2017
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Marco Vignuzzi joins Nels and Vincent to discuss recent work from his laboratory on redirecting RNA virus evolution in sequence space. Hosts: Nels Elde and Vincent Racaniello Guest: Marco Vignuzzi Become a patron of TWiEVO Vignuzzi LaboratoryRedirecting evolution of RNA viruses in sequence spacequasispecies concept This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. Get $30 off your first order and free shipping...

Duration:01:33:57

TWiEVO 23: The Alus are going to be alright

9/20/2017
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Nels and Vincent reveal how the protein DHX9 suppresses RNA processing defects caused by invasion of the Alu retroelement into the human genome. Hosts: Nels Elde and Vincent Racaniello Become a patron of TWiEVO Alu defectsAsifa Akhtar This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free with your first purchase – WITH FREE SHIPPING – by going to...

Duration:01:14:39